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Accuracy of Patient Age Estimation from Frontal Chest Radiographs of Adult Patients

Open Journal of Radiology 2022年第2期12卷 37-48页

作者： Sarah Chibane Alexandre Semionov John Kosiuk Josephine Pressacco karl sayegh Gianni Giancaspro Aline Khatchikian Paul S. Benvenuto Joshua Chin Sukhmanjit Ghumman Abdulrahman Maimani Department of Diagnostic Radiology McGill University Health Centre Montreal Canada

Objective: The objective of this study is to evaluate the accuracy of patient age estimation from frontal chest radiographs of adult patients. Methods: 195 posterior-anterior chest radiographs without significant abnormalities were shown to 5 staff radiologists and 6 radiology residents, who were asked to provide their estimates of patient age to the nearest decade. Real patient age distribution ranged from 16 to 91 years of age. Results: On average, correct estimate of patient age decade was made in 22% of cases. Staff radiologists were overall more accurate in their estimations compared to residents. Best accuracy was achieved by the radiologist with the most years of clinical experience, however overall accuracy did not tend to correlate with number of years in practice for staff, nor years of post-graduate training for residents. Overall, patient age was most often overestimated. The least accurate estimates were made for patients younger than 20 years and older than 90. Best accuracy was seen for patients between 50 and 70 years of age. For patients between 20 and 90 years of age, overall estimates were within 11 - 15 years of their true age. There was no significant difference in accuracy of age estimation between radiographs of women and men. Conclusions: Average rate of correct age estimation to the nearest decade from normal frontal chest radiographs in our study was 22%. Staff radiologists were more accurate than radiology residents. Best estimates were made for middle-aged patients, and worst for extremes of age.

关键词： Age Estimation Chest Radiography Radiology Residents

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Development and Validation of a Scaled Electric Combat Vehicle Tire Model

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World Journal of Engineering and Technology 2024年第1期12卷 24-39页

作者： Haniyeh Fathi Aricha Mehrotra Zeinab El-sayegh Department of Automotive and Mechatronics Engineering Ontario Tech University Oshawa Canada

Pneumatic tire modeling and validation have been the topic of several research papers, however, most of these papers only deal with pneumatic passenger and truck tires. In recent years, wheeled-scaled vehicles have gained lots of attention as a feasible testing platform, nonetheless up to the authors’ knowledge there has been no research regarding the use of scaled tires and their effect on the overall vehicle performance characteristics. This paper presents a novel scaled electric combat vehicle tire model and validation technique. The pro-line lockdown tire size 3.00 × 7.35 is modeled using the Finite Element Analysis (FEA) technique and several materials including layered membrane, beam elements, and Mooney-Rivlin for rubber. The tire-rim assembly is then described, and the rigid body analysis is presented. The tire is then validated using an in-house custom-made static tire testing machine. The tire test rig is made specifically to test the pro-line tire model and is designed and manufactured in the laboratory. The tire is validated using vertical stiffness and footprint tests in the static domain at different operating conditions including several vertical loads. Then the tire is used to perform rolling resistance and steering analysis including the rolling resistance coefficient and the cornering stiffness. The analysis is performed at different operating conditions including longitudinal speeds of 5, 10, and 15 km/h. This tire model will be further used to determine the tractive and braking performance of the tire. Furthermore, the tire test rig will also be modified to perform cornering stiffness tests.

关键词： Tire Modeling Tire Testing Machine Vehicle Dynamics Unmanned Vehicle Modeling Finite Element Analysis Tire Mechanics

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Robotic management of urinary fistula

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Asian Journal of Urology 2024年第3期11卷 357-365页

作者： Luis G.Medina Randall A.Lee Valeria Celis Veronica Rodriguez Jaime Poncel Aref S.sayegh Rene Sotelo The Catherine and Joseph Aresty Department of Urology USC Institute of UrologyKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Division of Urology Department of SurgeryFox Chase Cancer CenterTemple University Health SystemPhiladelphiaPAUSA

Objectives:To highlight critical preoperative and intraoperative considerations in approaching fistula repair ***:A search of the literature was conducted to identify relevant articles pertaining to robotic management of urinary ***:Fistulae of the genitourinary tract can be a challenging dilemma for urologists,as definitive management may require surgical *** of both enteric and non-enteric fistulae are multifactorial,and successful repair hinges on the meticulous perioperative evaluation,planning,and *** open techniques can subject patients to increased morbidity and prolonged *** its introduction,the robotic surgical platform has continued to expand its *** three-dimensional visualization and tremor free wristed instrument movements have made the robotic platform an attractive option for genitourinary fistula ***:Robotic management of complex urinary fistulae is feasible in expert hands;more studies are needed to define its role in the treatment algorithm of this devastating conditions.

关键词： Fistula Robotic surgery Rectourethral Rectovesical Vesicovaginal

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Single-atom catalysts for the electrochemical reduction of carbon dioxide into hydrocarbons and oxygenates

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Carbon Energy 2024年第3期6卷 64-117页

作者： karl Adrian Gandionco Juwon Kim Lieven Bekaert Annick Hubin Jongwoo Lim Department of Chemistry Seoul National UniversitySeoulRepublic of Korea Research Group Electrochemical and Surface Engineering(SURF) Department of Materials and ChemistryVrije Universiteit BrusselBrusselsBelgium

The electrochemical reduction of carbon dioxide offers a sound and economically viable technology for the electrification and decarbonization of the chemical and fuel *** this technology,an electrocatalytic material and renewable energy-generated electricity drive the conversion of carbon dioxide into high-value chemicals and carbon-neutral *** the past few years,single-atom catalysts have been intensively studied as they could provide near-unity atom utilization and unique catalytic ***-atom catalysts have become one of the state-of-the-art catalyst materials for the electrochemical reduction of carbon dioxide into carbon ***,it remains a challenge for single-atom catalysts to facilitate the efficient conversion of carbon dioxide into products beyond carbon *** this review,we summarize and present important findings and critical insights from studies on the electrochemical carbon dioxide reduction reaction into hydrocarbons and oxygenates using single-atom *** is hoped that this review gives a thorough recapitulation and analysis of the science behind the catalysis of carbon dioxide into more reduced products through singleatom catalysts so that it can be a guide for future research and development on catalysts with industry-ready performance for the electrochemical reduction of carbon dioxide into high-value chemicals and carbon-neutral fuels.

关键词： electrocatalysis electrochemical CO_(2)reduction hydrocarbons oxygenates single-atom catalysts

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Endogenous hormones matters in evaluation of endocrine disruptive effects mediated by nuclear receptors

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Eco-Environment & Health 2024年第3期3卷 257-259页

作者： Yanbin Zhao karl Fent State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants School of Environmental Science and EngineeringShanghai Jiao Tong University800 Dongchuan RoadShanghai 200240China ETH Zürich Institute of Biogeochemistry and Pollution DynamicsDepartment of Environmental Systems ScienceCH-8092 ZürichSwitzerland

In recent decades,endocrine-disrupting chemicals(EDCs)have emerged as a prominent focus on environmental science and ***,extensive use of in vitro bioassays founded on ligand-receptor binding has facilitated the identification of a substantial number of potential EDCs,particularly agonists/antagonists of nuclear receptors such as estrogen receptors and thyroid hormone receptors[1].These datasets have significantly augmented the discovery of potential ***,when subjecting these compounds to in vivo exposures,spanning from teleost fish to rodents and humans,observations frequently deviated from in vitro anticipation[2,3].This discrepancy and the apparent lack of prognostic value are shared with the difficulties of in vitro-in vivo extrapolations in classical toxicological *** the utility of in vitro identification is without doubt,its potential EDCs require in vivo *** resulting complexity in EDCs outcomes,nevertheless,has not yet received adequate attention and thorough interpretation.

关键词： doubt confirmation identification

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Enemies atpeace:Recentprogressin Agrobacterium-mediated cereal transformation

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The Crop Journal 2024年第2期12卷 321-329页

作者： Shaoshuai Liu Ke Wang Shuaifeng Geng Moammar Hossain Xingguo Ye Aili Li Long Mao karl-Heinz Kogel State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Institute of Phytopathology Centre for BioSystemsLand Use and NutritionJustus Liebig UniversityHeinrich Buff-Ring 26-32D-35392GiessenGermany

Agrobacterium tumefaciens mediated plant transformation is a versatile tool for plant genetic engineering following its discovery nearly half a century *** modifications were made in its application to increase efficiency,especially in the recalcitrant major cereals *** breakthroughs in transformation efficiency continue its role as a mainstream technique in CRISPR/Cas-based genome editing and gene *** modifications led to higher transformation frequency and lower but more stable transgene copies with the capability to revolutionize modern *** this review,we provide a brief overview of the history of Agrobacterium-mediated plant transformation and focus on the most recent progress to improve the system in both the Agrobacterium and the host recipient.A promising future for transformation in biotechnology and agriculture is predicted.

关键词： Agrobacterium tumefaciens Cereal species Genome editing Genetic engineering Plant breeding

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Making the case for the evolving role of social media in health professions education and a literature review on the application of some in ophthalmology

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Annals of Eye Science 2024年第2期9卷 1-11页

作者： Helena Prior Filipe Mila Kostic Mildred Lopez karl Golnik West Lisbon Hospitals Center Hospital Egas MonizLisbonPortugal Egas Moniz Center for Interdisciplinary Research LisbonPortugal Continuing Education and Development in Health Professions RichboroPAUSA Coordinación de Educación en Salud Instituto Mexicano del Seguro Social(IMSS)Mexico CityMexico Department of Neurology Barrow Neurological InstitutePhoenixAZUSA Department of Ophthalmology University of CincinnatiCincinnatiOHUSA

Background and Objective:Social media(SoMe)has emerged as a tool in health professions education(HPE),particularly amidst the challenges posed by the coronavirus disease 2019(COVID-19)*** the academia’s initial skepticism SoMe has been gaining traction in supporting learning communities,and offering opportunities for innovation in *** study aims to explore the integration of SoMe in *** key components were outlined as necessary for a successful integration,and include designing learning experiences,defining educator roles,selecting appropriate platforms,and establishing educational ***:This article stemmed from the online Teaching Skills Series module on SoMe in education from the Ophthalmology Foundation,and drew upon evidence supporting learning theories relevant to SoMe integration and models of ***,we conducted a literature review considering Englishlanguage articles on the application of SoMe in ophthalmology from PubMed over the past *** Content and Findings:Early adopters of SoMe platforms in HPE have leveraged these tools to enhance learning experiences through interaction,dialogue,content sharing,and active learning *** integrating SoMe into educational programs,both online and in-person,educators can overcome time and geographical constraints,fostering more diverse and inclusive learning *** consideration is,however,necessary to address potential limitations within ***:This article lays groundwork for expanding SoMe integration in HPE design,emphasizing the supportive scaffold of various learning theories,and the need of furthering robust research on examining its advantages over traditional educational *** literature review underscores an ongoing multifaceted,random application of SoMe platforms in ophthalmology *** advocate for an effective incorporation of SoMe in HPE education,with the need to comply with good educational practice.

关键词： Social media(SoMe) health professions education(HPE) active learning social learning technology enhanced learning

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Dynamic convergent shock compression initiated by return current in high-intensity laser-solid interactions

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Matter and Radiation at Extremes 2024年第4期9卷 40-53页

作者： Long Yang Martin Rehwald Thomas Kluge Alejandro LasoGarcia Toma Toncian karl Zeil Ulrich Schramm Thomas E.Cowan Lingen Huang Helmholtz-Zentrum Dresden-Rossendorf 01328 DresdenGermany Technische Universitat Dresden 01062 DresdenGermany

We investigate the dynamics of convergent shock compression in solid cylindrical targets irradiated by an ultrafast relativistic laser *** particle-in-cell simulations and coupled hydrodynamic simulations reveal that the compression process is initiated by both magnetic pressure and surface ablation associated with a strong transient surface return current with density of the order of 10^(17) A/m^(2) and lifetime of 100 *** results show that the dominant compression mechanism is governed by the plasma β,i.e.,the ratio of thermal pressure to magnetic *** targets with small radius and low atomic number Z,the magnetic pressure is the dominant shock compression *** to a scaling law,as the target radius and Z increase,the surface ablation pressure becomes the main mechanism generating convergent ***,an indirect experimental indication of shocked hydrogen compression is provided by optical shadowgraphy measurements of the evolution of the plasma expansion *** results presented here provide a novel basis for the generation of extremely high pressures exceeding Gbar(100 TPa)to enable the investigation of high-pressure physics using femtosecond J-level laser pulses,offering an alternative to nanosecond kJ-laser pulse-driven and pulsed power Z-pinch compression methods.

关键词： shock convergent return

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Cytoplasmic DNA: sources, sensing, and role in aging and disease

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四川生理科学杂志 2024年第4期46卷 89-89页

作者： karl N Miller Aging Cancer and Immuno-oncology Program Sanford Burnham Prebys Medical Discovery Institute La Jolla CA 92037 USA Department of Physiology and Biomedical Engineering Mayo Clinic Rochester MN 55905 USA

Endogenous cytoplasmic DNA(cytoDNA)species are emerging as key mediators of inflammation in diverse physiological and pathological *** the role of endogenous cytoDNA in innate immune activation is well established,the cytoDNA species themselves are often poorly characterized and difficult to distinguish,and their mechanisms of formation,scope of function and contribution to disease are incompletely understood.

关键词： endogenous inflammation incomplete

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Ultra-high spatio-temporal resolution imaging with parallel acquisition-readout structured illumination microscopy(PAR-SIM)

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Light(Science & Applications) 2024年第6期13卷 1140-1158页

作者： Xinzhu Xu Wenyi Wang Liang Qiao Yunzhe Fu Xichuan Ge Kun Zhao karl Zhanghao Meiling Guan Xin Chen Meiqi Li Dayong Jin Peng Xi Department of Biomedical Engineering College of Future TechnologyPeking UniversityBeijing100871China Wallace H.Coulter Dept.of Biomedical Engineering Georgia Institute of Technology and Emory UniversityAtlanta30332GAUSA National Biomedical Imaging Center Peking UniversityBeijing100871China Department of Biomedical Engineering College of EngineeringSouthern University of Science and TechnologyShenzhen518055GuangdongChina Airy Technologies Co. Ltd.Beijing100086China Eastern Institute for Advanced Study Eastern Institute of TechnologyNingboZhejiang315200China School of Life Science Peking UniversityBeijing100871China Institute for Biomedical Materials and Devices(IBMD) Faculty of ScienceUniversity of Technology SydneySydneyNSW2007Australia

Structured illumination microscopy(SIM)has emerged as a promising super-resolution fluorescence imaging technique,offering diverse configurations and computational strategies to mitigate phototoxicity during real-time imaging of biological *** efforts to enhance system frame rates have concentrated on processing algorithms,like rolling reconstruction or reduced frame reconstruction,or on investments in costly sCMOS cameras with accelerated row readout *** this article,we introduce an approach to elevate SIM frame rates and region of interest(ROI)coverage at the hardware level,without necessitating an upsurge in camera expenses or intricate ***,parallel acquisition-readout SIM(PAR-SIM)achieves the highest imaging speed for fluorescence imaging at currently available detector *** using the full frame-width of the detector through synchronizing the pattern generation and image exposure-readout process,we have achieved a fundamentally stupendous information spatial-temporal flux of 132.9 MPixels·s^(−1),9.6-fold that of the latest techniques,with the lowest SNR of−2.11 dB and 100 nm ***-SIM demonstrates its proficiency in successfully reconstructing diverse cellular organelles in dual excitations,even under conditions of low signal due to ultra-short exposure ***,mitochondrial dynamic tubulation and ongoing membrane fusion processes have been captured in live COS-7 cell,recorded with PAR-SIM at an impressive 408 *** posit that this novel parallel exposure-readout mode not only augments SIM pattern modulation for superior frame rates but also holds the potential to benefit other complex imaging systems with a strategic controlling approach.

关键词： hardware illumination resolution

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