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Ileal loop interposition:an alternative biliary bypass technique

Hepatobiliary & Pancreatic Diseases International 2010年第6期9卷 654-657页

作者： Felipe JF Coimbra Alessandro L Diniz Heber SC Ribeiro Wilson L costa Jr. Eduardo NP Lima andréL Montagnini Abdominal Surgery Department Hospital do Cncer A.C.CamargoRua Professor Antnio Prudente 211LiberdadeSo PauloSP 01509-010Brazil Nuclear Medicine Imaging Department Hospital do Cncer A.C.CamargoRua Professor Antnio Prudente 211LiberdadeSo PauloSP 01509-010Brazil

BACKGROUND:Obstructive jaundice is a common condition in advanced digestive *** procedures can improve quality of life and allow patients to attempt a systemic *** anastomosis is still the procedure of choice for patients in many *** a surgical bypass is not possible,biliary drainage can be done by placing endoscopic or transparietal stents,which are less durable methods even when an expandable stent is employed. METHODS:A 47-year-old male with an excellent clinical status and a previous cholecystectomy and an exploratory laparotomy for advanced gastric cancer was referred with obstructive jaundice.A preoperative CT scan showed a dilated bile duct and a small mass at the distal hepatic *** other signs of metastasis were found.A surgical bilioenteric anastomosis was *** surgery,a distal choledochal obstruction and a mesenteric retraction by a lymph node mass prevented the jejunum to ascend for a bilioenteric anastomosis. Surgically,an alternative bilioenteric bypass was performed by means of an ileal loop interposition between the bile duct and the jejunum. RESULT:The recovery of the patient was uneventful and his bilirubin levels normalized after one *** patient was then referred for systemic chemotherapy. CONCLUSIONS:This alternative biliary bypass can be safely and easily performed,and may be a good alternative for patients already referred for surgery because of a better life expectancy and when the jejunum is not an alternative.

关键词： biliary bypass ileal loop interposition biliary cancer

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Biochar influences the cane fields’microbiota and the development of pre-sprouted sugarcane seedlings

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Waste Disposal and Sustainable Energy 2023年第1期5卷 75-88页

作者： Bruna Cristina Pinto Adriana Barboza Alves Osania Emerenciano Ferreira Gustavo Henrique Gravatim costa Magno andréde Oliveira Augusto Cesar da Silva Bezerra Alan Rodrigues Teixeira Machado Postgraduate Program in Environmental Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38202-436Brazil Department of Agricultural and Biological Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38208-436Brazil Postgraduate Program in Geotechnical Engineering Federal University of Ouro PretoOuro PretoMinas Gerais35400-000Brazil Department of Transport Engineering Federal Center for Technological Education of Minas GeraisBelo HorizonteMinas Gerais30421-169Brazil Department of Exact Sciences State University of Minas GeraisJoão Monlevade UnityJoão MonlevadeMinas Gerais35930-314Brazil

This research investigates the soil conditioning effect of sugar cane fields with biochar produced from sugarcane *** influence on the physicochemical and microbiological conditions of the soil and the agronomic performance of sugarcane seedlings was *** this end,the biochar from sugarcane bagasse was produced by pyrolysis in a double drum oven and mixed with soil at rates of 0,1%,3%,and 5%(in weight).The experiment was installed in a greenhouse with two evaluation periods(30 days and 60 days)and five *** pot received a pre-sprouted cane seedling,and the analysis of colony-forming units(bacteria and fungi),physicochemical characteristics of the soil,and growth and development of sugarcane were performed per *** biochar showed a high fixed carbon content(72%)and a specific surface area estimated by the adsorption of methylene blue of 50 m2 g−***,its structure is porous and contains important nutrients(e.g.,CaO,K2O,and P2O5).In the periods evaluated,the applications of the 3%and 5%(in weight)rates of biochar reduced most of the soil fertility ***,the chemical analyses indicated that the sugarcane field soil collected already possessed high *** microbiota was influenced,but only the application of the 3%(in weight)rate at 60 days after planting showed a significant positive effect on the number of bacteria forming units,with an increase of approximately 385%.On the other hand,no significant positive effect on sugarcane development was ***,biochar application in high-fertility sugarcane plantation soil did not result in gains for sugarcane development in the periods evaluated.

关键词： Soil Biometry Microbiology Double drum oven Biochar

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International cooperation in science,technology,and health,challenges and perspectives

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hLife 2024年第5期2卷 207-210页

作者： andrécosta Lobato Carlos Medicis Morel Yi Shen Institute of Economics Federal University of Rio de JaneiroRio de JaneiroBrazil Center for Technology Development in Health Oswaldo Cruz FoundationRio de JaneiroBrazil Federal University of Rio de Janeiro Rio de JaneiroBrazil International Research Institution of Global Cyberspace Governance Fudan UniversityShanghaiChina

International cooperation in science and technology is a major challenge for developing countries such as Brazil and *** the“safari research,”in which poor countries enter with the disease and the rich countries with technology,to new frameworks such as the BRICS,professors Carlos Medicis Morel,from Brazil’s Oswaldo Cruz Foundation,and Yi Shen,from China’s Fudan University,have a dialogue mediated by andrécosta Lobato,on the challenges and perspectives for cooperation in the global *** the bottom-up process usually leads to fruitful cooperation,the top–down political support is relevant to provide a proper environment for *** dialogue explored the differences in scientific structures between Brazil and China,language barriers,and the need for effective *** discussed the evolution of BRICS beyond economic cooperation,emphasizing its role in global governance,science,technology,and *** professors addressed the benefits of international collaboration,including knowledge exchange,exposure to different cultures,and solving common problems.

关键词： cooperation Brazil technology

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Influence of fire on woody vegetation of savanna and forest formations in the Cerrado biome

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Journal of Forestry Research 2023年第5期34卷 1207-1216页

作者： Aline das Gracas costa Fillipe Tamiozzo Pereira Torres Gumercindo Souza Lima Fabiano Rodrigues de Melo Carlos Moreira Miquelino Eleto Torres Bruno Leao Said Schettini Vicente Paulo Santana Neto andréLuiz Lopes de Faria Department of Forest Engineering Federal University of VicosaUFVVicosaMG 36570-900Brazil Department of Geography Federal University of VicosaUFVVicosaMG 36570-900Brazil

Wildfires have environmental,economic,and social impacts,and can shape the landscape and benefit ecosystems such as the *** study evaluated the diversity,similarity,and floristic and structural differences of woody savanna and forest formations of the Cerrado,when affected and not affected by ***-eight 25-400m2 plots were randomly allocated and divided into Burnt Cerrado and Unburnt Cerrado,Burnt Forest,and Unburnt Forest,and divided into three levels of inclusion according to diameter class(smaller than 2 cm,2-5 cm and larger than5 cm).Species were identified,DBH and height measured,and phyto sociological parameters such as volume,diversity,and floristic similarity *** Cerrado had lower diversity,density,and dominance at all inclusion levels compared to the Unburnt Cerrado,and showed similarities between treatments at the inclusion *** Forest had smaller differences in diversity,density,and dominance than Unburnt *** formation was similar at level 1 of inclusion and in the total ***,it was dissimilar at lower *** lower density and diversity of species at the lowest levels of inclusion was associated with mortality from fire.

关键词： Biodiversity Brazil Burning Floristic Phytosociology

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CRISPR/Cas9: Development and Application in Rice Breeding

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Rice science 2019年第5期26卷 265-281页

作者： Fernando Matías ROMERO andrés GATICA-ARIAS Laboratory of Plant Biotechnology School of Biology/Research Center in Cellular and Molecular Biology University of Costa Rica

Rice(Oryza sativa L.)is an important staple food crop worldwide due to its adaptability to different environmental *** of its great economic and social importance,there is a constant requirement for new varieties with improved agronomic characteristics,such as tolerance to different biotic(such as bacterium,fungus,insect and virus)and abiotic stresses(such as salinity,drought and temperature),higher yield and better organoleptic and nutritional *** the new genome editing technologies,the clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein(Cas)(CRISPR/Cas)system allows precise and specific edition in a targeted genome *** is one of the most frequently used techniques for the study of the function of new genes and for the development of mutant lines with enhanced tolerance to biotic and abiotic stresses,herbicide resistance or improved *** wide varieties of applications for this technology include simple non-homologous end joining,homologous recombination,gene replacement,and base *** this review,we analyzed how some of these applications have been used in rice cultivars to obtain rice varieties better adapted to current environmental conditions and market requirements.

关键词： rice CRISPR Cas genome editing biotic stress abiotic stress yield off-target mutation

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Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

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World Journal of Gastroenterology 2017年第37期23卷 6854-6867页

作者： Diego Marques Layse Raynara Ferreira-costa Lorenna Larissa Ferreira-costa Romualdo da Silva Correa Aline Maciel Pinheiro Borges Fernanda Ribeiro Ito Carlos Cesar de Oliveira Ramos Raul Hernandes Bortolin andré Ducati Luchessi andrea Ribeiro-dos-Santos Sidney Santos Vivian Nogueira Silbiger Laboratório de Bioanálise e Biotecnologia Molecular Universidade Federal do Rio Grande do Norte Programa de Pós-graduacao em Ciências Farmacêutica Universidade Federal do Rio Grande do Norte Laboratório de Genética Humana e Médica Universidade Federal do Pará Departamento de Cirurgia Oncológica Liga Norte Riograndense Contra o Cancer Laboratório de Patologia eCitopatologia Liga Norte Riograndense Contra o Cancer Depart-amento de Análises Clínicas e Toxicológicas Universidade Federal do Rio Grande do Norte Núcleo de Pesquisas em Oncologia Universidade Federal do Pará

AIM To investigate the association between 16 insertiondeletions(INDEL) polymorphisms, colorectal cancer(CRC) risk and clinical features in an admixed *** O n e h u n d re d a n d fo r ty p a t i e n t s w i t h C R C a n d 140 cancer-free subjects were examined. Genomic DNA was extracted from peripheral blood samples. Polymorphisms and genomic ancestry distribution were assayed by Multiplex-PCR reaction, separated by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and analyzed on Gene Mapper ID v3.2. Clinicopathological data were obtained by consulting the patients' clinical charts, intra-operative documentation, and pathology *** Logistic regression analysis showed that polymorphism variations in IL4 gene was associated with increased CRC risk, while TYMS and UCP2 genes were associated with decreased risk. Reference to anatomical localization of tumor Del allele of NFKB1 and CASP8 were associated with more colon related incidents than rectosigmoid. In relation to the INDEL association with tumor node metastasis(TNM) stage risk, the Ins alleles of ACE, HLAG and TP53(6 bp INDEL) were associated with higher TNM stage. Furthermore, regarding INDEL association with relapse risk, the Ins alleles of ACE, HLAG, and UGT1A1 were associated with early relapse risk, as well as the Del allele of TYMS. Regarding INDEL association with death risk before 10 years, the Ins allele of SGSM3 and UGT1A1 were associated with death *** The INDEL variations in ACE, UCP2, TYMS, IL4, NFKB1, CASP8, TP53, HLAG, UGT1A1, and SGSM3 were associated with CRC risk and clinical features in an admixed population. These data suggest that this cancer panel might be useful as a complementary tool for better clinical management, and more studies need to be conducted to confirm these findings.

关键词： Colorectal cancer Ins-del polymorphism Admixed population Potential biomarker Diagnostic Risk stratification Prognostic Clinical features

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Observing Network Performance and Congestion on Managing Assets with RFID and Cloud Computing

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Journal of Computer and Communications 2017年第9期5卷 43-66页

作者： Leandro andrioli Rodrigo da Rosa Righi Cristiano andré da costa Lucas Graebin Applied Computing Graduate Program Universidade do Vale do Rio dos Sinos (Unisinos) S&#227 o Leopoldo RS Brazil

Today, we observe that more and more, radio frequency identification (RFID) technology has been used to identify and track objects in enterprises and institutions. In addition, we also perceive the growing adoption of cloud computing, either public or private, to process and store data from the objects. In this context, the literature does not present an initiative that looks into the network on enterprise-cloud interactions, so neglecting network performance and congestion information when transmitting data to the cloud. Thus, we are presenting a model named ACMA—Automatic Control and Management of Assets. ACMA employs context awareness to control and monitor corporate assets in companies with multiple units. ACMA provides a centralized point of access in the cloud in which interested actors can get online data about each corporate asset. In particular, our scientific contribution consists in considering network congestion to control dynamically the data updating interval from sensors to the cloud. The idea is to search for reliability and integrity of operations, without losing or corrupting data when updating the information to cloud. Thus, this article describes the ACMA model, its architecture, algorithms and features. In addition, we describe the evaluation methodology and the results obtained through experiments and simulations based on the developed prototype.

关键词： Internet of Things RFID Cloud Computing Network Congestion Adaptivity Assets

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打造友善合作空间:中国和巴西基于多学科领域的全球健康合作

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Science Bulletin 2023年第20期68卷 2293-2294页

作者： andre costa Lobato Carlos Medicis Morel George Fu Gao Institute of Economics Federal University of Rio de JaneiroRio de Janeiro 22290-902Brazil Center for Technology Development in Health Oswaldo Cruz FoundationRio de Janeiro 21040-361Brazil Federal University of Rio de Janeiro Rio de Janeiro 22290-902Brazil CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China

Brazilian president Luiz Inacio Lula da Silva’s visit to China in April 2023 was an opportunity to elevate health cooperation between the two countries to scientific and technological cooperation standards,exemplified by the China-Brazil Earth Resources Satellite(CBERS).The satellite programme can be traced back to the Basic Agreement on Scientific and Technological Cooperation signed by the two nations in 1982(https://***/ccivil03/decreto/1990-1994/***).This framework serves as a reference for health cooperation between Chinese science and health institutions and the Oswaldo Cruz Foundation(Fiocruz),the Brazilian Minister of Health’s core industrial and research facility.

关键词： cooperation Basic Brazil

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Trichomonas vaginalis perturbs the junctional complex in epithelial cells

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Cell Research 2005年第9期 29-41页

作者： Rodrigo Furtado MADEIRO da costa,Wanderley de SOUZA,Marlene BENCHIMOL,John F ALDERETE,José andrés MORGADO-DíAZ Programa de Pós Graduao em Ciências Morfológicas Universidade Federal do Rio de Janeiro Rio de Janeiro RJ 20231- 050 Brazil Grupo de Biologia Estrutural Diviso de Biologia Celular Centro de Pesquisa Instituto Nacional de Cancer Rio de Janeiro RJ 20231-050 Brazil Grupo de Biologia Estrutural Diviso de Biologia Celular Centro de Pesquisa Instituto Nacional de Cancer Rio de Janeiro RJ 20231-050 Brazil Laboratório de Ultraestrutura Celular Hertha Meyer Instituto de Biofísica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Centro de Ciências da Saúde Rio de Janeiro RJ 21944-900 Brazil Laboratório de Ultraestrutura Celular Universidade Santa úrsula Rio de Janeiro RJ 22231-010 Brazil Department of Microbiology University of Texas Health Science Center San Antonio TX 78229-3900 USA Grupo de Biologia Estrutural Diviso de Biologia Celular Centro de Pesquisa Instituto Nacional de Cancer Rio de Janeiro RJ 20231-050 Brazil

Trichomonas vaginalis, a protist parasite of the urogenital tract in humans, is the causative agent of trichomonosis, which in recent years have been associated with the cervical cancer development. In the present study we analyzed the modifications at the junctional complex level of Caco-2 cells after interaction with two isolates of T. vaginalis and the influence of the iron concentration present in the parasite’s culture medium on the interaction effects. Our results show that T. vaginalis adheres to the epithelial cell causing alterations in the junctional complex, such as: (a) a decrease in transepithelial electrical resistance; (b) alteration in the pattern of junctional complex proteins distribution as observed for E-cadherin, occludin and ZO-1; and (c) enlargement of the spaces between epithelial cells. These effects were dependent on (a) the degree of the parasite virulence isolate, (b) the iron concentration in the culture medium, and (c) the expression of adhesin proteins on the parasite surface.

关键词： Trichomonas vaginalis Caco-2 junctional complex proteins transepithelial electrical resistance adhesins.

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Paleoproterozoic juvenile magmatism within the northeastern sector of the Sao Francisco paleocontinent:Insights from the shoshonitic high Ba-Sr Montezuma granitoids

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Geoscience Frontiers 2020年第5期11卷 1821-1840页

作者： Samuel Moreira Bersan Alice Fernanda de Oliveira costa andre Danderfer Francisco Roberio de Abreu Cristiano Lana Glaucia Queiroga Craig Storey Hugo Moreira Universidade Federal de Ouro Preto Programa de Pos-graduacaoDepartamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Universidade Federal de Ouro Preto Departamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Sustain Geologia Ltda Teresa M.Valadares 503/502Belo HorizonteMGCEP 30575-160Brazil University of Portsmouth School of Earth and Environmental SciencesBurnaby BuildingBurnaby RoadPortsmouthPO13QLUK

New,integrated petrographic,mineral chemistry,whole rock geochemical,zircon and titanite UPb geochronology,and zircon Hf isotopic data from the Montezuma granitoids,as well as new geochemical results for its host rocks represented by the Corrego Tingui Complex,provides new insights into the late-to post-collisional evolution of the northeastern Sao Francisco paleocontinent.U-Pb zircon dates from the Montezuma granitoids spread along the Concordia between ca.2.2 Ga to 1.8 Ga and comprise distinct *** I have crystallization ages between ca.2.15 Ga and 2.05 Ga and are interpreted as inherited *** II zircon dates vary from 2.04 Ga to1.9 Ga and corresponds to the crystallization of the Montezuma granitoids,which were constrained at ca.2.03 Ga by the titanite U-Pb *** age zoning is common within the ca.1.8 Ga Group III zircon ages,being related to fluid isotopic re-setting during the Espinhaco rifiting ***εHf(t)analysis show dominantly positive values for both Group I(-4 to+9)andⅡ(-3 to+8)zircons and TDM2 model ages of 2.7-2.1 Ga and 2.5-1.95 Ga,***,the Montezuma granitoids are weakly peraluminous to metaluminous magnesian granitoids,enriched in LILES and LREE,with high to moderate Mg#and depleted in some of the *** lithochemical signature,added to the juvenile signature of both inherited and crystallized zircons,allowed its classification as a shoshonitic high Ba-Sr granitoid related to a late-to post-collisional lithosphere delamination followed by asthenospheric *** this scenario,the partial melting of the lithospheric mantle interacted with the roots of an accreted juvenile intra-oceanic arc,being these hybrid magma interpreted as the source of the Montezuma *** Corrego Tingui Complex host rocks are akin to a syn-to late-collisional volcanic arc granitoids originated from the partial melting of ancient crustal *** results presented in this study have revealed the occurrence of j

关键词： Zircon U–Pb-Hf Titanite U–Pb High Ba–Sr Late-to post-collisional Sao Francisco paleocontinent

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