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Nano Research 2024年第1期17卷 407-415页

作者： Yumei Ma Lijie Zhang kang Zhu Binze Zhang Ranran Peng Changrong Xia Ling huang State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources College of ChemistryXinjiang UniversityUrumqi 830046China Department of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

Promoting the oxygen reduction reaction(ORR)is critical for commercialization of intermediate-temperature solid oxide fuel cells(IT-SOFCs),where Sr_(2)Fe_(1.5)Mo_(0.5)O_(6)−δ(SFM)is a promising cathode by working as a mixed ionic and electronic *** this work,doping of In^(3+)greatly increases the oxygen vacancy concentration and the content of adsorbed oxygen species in Sr_(2)Fe_(1.5)Mo_(0.5−x)InxO_(6−δ)(SFMInx),and thus effectively promotes the ORR *** a typical example,SFMIn_(0.1)reduces the polarization resistance(R_(p))from 0.089 to 0.046Ω∙cm^(2)at 800°C,which is superior to those doped with other metal *** addition,SFMIn0.1 increases the peak power density from 0.92 to 1.47 W∙cm^(−2)at 800°C with humidified H_(2)as the fuel,indicating that In3+doping at the Mo site can effectively improve the performance of SOFC cathode material.

关键词： solid oxide fuel cell cathode In3+doping oxygen reduction reaction(ORR) Sr_(2)Fe_(1.5)Mo_(0.5)O_(6-δ)

Fabrication and modification of implantable optrode arrays for in vivo optogenetic applications

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Biophysics Reports 2018年第2期4卷 82-93页

作者： Lulu Wang kang huang Cheng Zhong Liping Wang Yi Lu Shenzhen Key Lab of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science CAS Center for Excellence in Brain Science and Intelligence Technology The Brain Cognition and Brain Disease Institute Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen College of Advanced Technology University of Chinese Academy of Sciences

Recent advances in optogenetics have established a precisely timed and cell-specific methodology for understanding the functions of brain circuits and the mechanisms underlying neuropsychiatric disorders. However, the fabrication of optrodes, a key functional element in optogenetics, remains a great challenge. Here, we report reliable and efficient fabrication strategies for chronically implantable optrode arrays. To improve the performance of the fabricated optrode arrays, surfaces of the recording sites were modified using optimized electrochemical processes. We have also demonstrated the feasibility of using the fabricated optrode arrays to detect seizures in multiple brain regions and inhibit ictal propagation in vivo. Furthermore, the results of the histology study imply that the electrodeposition of composite conducting polymers notably alleviated the inflammatory response and improved neuronal survival at the implant/neural-tissue interface. In summary, we provide reliable and efficient strategies for the fabrication and modification of customized optrode arrays that can fulfill the requirements of in vivo optogenetic applications.

关键词： Optogenetics Optrode Neural electrode Electrodeposition Optical stimulation Electrophysiological recording

基于希尔伯特—黄变换的铁路桥梁结构健康监测

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中国铁道科学 2006年第1期27卷 1-7页

作者： Norden huang kang huang 王成国（译）齐法琳（译）李海涛（译） NASA Goddard Space Flight Center Greenbelt Maryland 20771 USA Accelerated Cost-Effect Transit for Century 21 1201 Main Street Suite 800 Dallas TX 75202 USA 不详

桥梁结构健康监测直观检查法具有一定的局限性。新的基于希尔伯特—黄变换(HHT)的非破坏性桥梁结构健康监测方法,依赖于瞬变荷载测试和简便的数据收集,核心是近年来针对非稳态和非线性时间序列分析而新发展起来的HHT,由经验模态分解和Hi... 详细信息

桥梁结构健康监测直观检查法具有一定的局限性。新的基于希尔伯特—黄变换(HHT)的非破坏性桥梁结构健康监测方法,依赖于瞬变荷载测试和简便的数据收集,核心是近年来针对非稳态和非线性时间序列分析而新发展起来的HHT,由经验模态分解和Hilbert谱分析构成。该方法对桥梁结构健康性的最终判断依据是基于数据的非线性特征、自由振动和强迫振动的频率对比、桥梁对轻荷载及重荷载的响应。该方法的优点是:无需以前的数据,简便的数据采集,最少程度地干扰交通,以及细微差别的精确定量解释。工程实例的分析结果表明这种新方法应用于铁路桥梁结构健康监测的可行性。

关键词：希尔伯特-黄变换铁路桥梁结构健康监测

Review of the Tuned Mass Damper Inerter(TMDI)in Energy Harvesting and Vibration Control:Designs,Analysis and Applications

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2361-2398页

作者： Xiaofang kang Qiwen huang Zongqin Wu Jianjun Tang Xueqin Jiang Shancheng Lei School of Civil Engineering Anhui Jianzhu UniversityHefei230601China Key Laboratory of Intelligent Underground Detection Technology Anhui Jianzhu UniversityHefei230601China Chengnan College Changsha University of Science and TechnologyChangsha410015China

Tuned mass damper inerter(TMDI)is a device that couples traditional tuned mass dampers(TMD)with an inertial *** inertial device produces resistance proportional to the relative acceleration at its two ends through its“inertial”*** to its unique mechanical properties,TMDI has received widespread attention and application in the past twenty *** different configurations are required in different practical situations,TMDI is still active in the research on vibration control and energy harvesting in *** paper provides a comprehensive review of the research status of *** work first examines the generation and important vibration control characteristics of ***,the energy harvesting performance of electromagnetic tuned mass damper inerter(EM-TMDI)is *** work emphasizes the formation of a passive dynamic vibration absorber by coupling traditional TMD with inertial *** paper also summarizes the design and implementation of optimal vibration control and energy harvesting for ***,this paper details the applications of TMDI in the fields of bridges and building ***,this paper summarizes the necessity of research on tuned mass-damper-inertia,the challenges faced currently,and future research directions,such as control of parameters in electromagnetic energy harvesting TMDI systems and low-cost TMDI.

关键词： TMDI EM-TMDI energy harvesting vibration control inertial device

A New Lyapunov Based Robust Control for Uncertain Mechanical Systems

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自动化学报 2014年第5期40卷 875-882页

作者： ZHEN Sheng-Chao ZHAO Han CHEN Ye-Hwa huang kang School of Mechanical and Automotive Engineering Hefei University of Technology Hefei 230009 China The George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta Georgia 30332 USA

We design a new robust controller for uncertain mechanical systems. The inertia matrix's singularity and upper bound property are first analyzed. It is shown that the inertia matrix may be positive semi-definite due to over-simplified model. Further-more, the inertia matrix's being uniformly bounded above is also limited. A robust controller is proposed to suppress the effect of uncertainty in mechanical systems with the assumption of uniform positive definiteness and upper bound of the inertia matrix. We theoretically prove that the robust control renders uniform boundedness and uniform ultimate boundedness. The size of the ultimate boundedness ball can be made arbitrarily small by the designer. Simulation results are presented and discussed.

关键词：鲁棒控制器 Lyapunov 机械系统惯性矩阵一致有界系统不确定性一致最终有界仿真结果

Fractionation characteristics of magnesium isotope in the ancient weathering crust

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Petroleum Science 2023年第3期20卷 1446-1457页

作者： Jia-Qi Yang Jun-Tao Zhang Zhi-Liang He Ni-Na Luo Xiao-Hui Jjin Tao Zhang Ning Gu kang-Jun huang jian Gao School of Energy Resources China University of GeosciencesBeijing100083China SINOPEC Exploration and Production Research Institute Beijing100083China China Petrochemical Corporation Ltd. Beijing100728China Key Laboratory of Deep Geology and Resources SINOPECBejing102206China Chongqing Gas Field of Petro China Southwest Oil and Gas Field Company Chongqing400021China Shaanxi Key Laboretory of Early Life and Environments Department of GeologyNorthwest UniversityXi'anShaanxi710069China

Weathering has always been a concerned around the world,as the first and most important step in the global cycle of elements,which leads to the fractionation of isotopes on the scale of geological *** Middle Ordovician Majiagou Formation in Daniudi area of the Ordos Basin had experienced weathering for>130 *** thin section observation,major and trace element analysis,carbon,oxygen,and magnesium isotopes composition analysis,the dolomitization modes and weathering of ancient dolo-mite in Daniudi area were analyzed in *** results showed that the Sabkha and brine-reflux dolomitization modes had developed,and the Mg isotopes in different layers of the karst crust were fractionated by various *** vertical vadose zone was affected by weathering,the Mg isotope of dolomite(δ^(26)Mgdol)showed a downward decreasing trend;the horizontal underflow zone was controlled by diagenesis and formation fluid,δ^(26)Mgdol showed a vertical invariance and negative;the main reason for Mg isotope fractionation in the deep slow-flow zone was the brine-reflux dolomitization mode during early burial period,which showed a vertical downward ***,the Mg isotope characteristic data of the ancient weathering crust were provided and the process of Mg isotope frac-tionationinthekarstcrust was explained.

关键词： Magnesium isotope Dolomitization mode Weathering Ancient weathering crust Ordos Basin

体外冲击波治疗通过激活Wnt5a/Ca^(2+)信号通路改善大鼠股骨牵张成骨的分子机制

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河北医科大学学报 2024年第1期45卷 40-46页

作者：黄康斌陈曾凤陈从山张远洋邱志伟湖北省十堰市太和医院推拿科湖北十堰442000 湖北省十堰市太和医院中西医结合科湖北十堰442000

目的探究体外冲击波治疗通过激活Wnt5a/Ca^(2+)信号改善大鼠股骨牵张成骨的机制。方法 60只8周龄Sprague Dawley雄性大鼠分为对照组、股骨牵张模型组和体外冲击波疗法(extracorporeal shock wave therapy,SWT)组(n=20)。使用Cat Walk X... 详细信息

目的探究体外冲击波治疗通过激活Wnt5a/Ca^(2+)信号改善大鼠股骨牵张成骨的机制。方法 60只8周龄Sprague Dawley雄性大鼠分为对照组、股骨牵张模型组和体外冲击波疗法(extracorporeal shock wave therapy,SWT)组(n=20)。使用Cat Walk XT系统测量大鼠步态参数。通过显微CT(Micro-CT)扫描分析大鼠股骨形态。组织病理学分级采用Mankin评分标准,并分析软骨下骨各区域Wnt5a阳性细胞百分比。实时聚合酶链反应分析大鼠股骨Ⅰ型胶原和骨桥蛋白mRNA表达。免疫组织化学染色分析骨形态发生蛋白2(bone morphogenetic protein 2,BMP2)、血管内皮生长因子(vascular endothelial growth factor,VEGF)和增殖细胞核抗原(proliferating cell nuclear antigen,PCNA)的表达。蛋白印迹分析Wnt5a/Ca^(2+)信号通路蛋白表达。结果模型组摆动速度、最大接触面积、单站姿、占空比和支架摆动时间低于对照组,ESWT组摆动速度、最大接触面积、单站姿、占空比和支架摆动时间高于模型组(P<0.05)。模型组骨小梁体积分数、小梁厚度和骨密度小于对照组,ESWT组骨小梁体积分数、小梁厚度和骨密度大于模型组(P<0.05)。模型组股关节病理组织学(Mankin)评分高于对照组,Wnt5a阳性细胞数量少于对照组,ESWT组股关节Mankin评分低于模型组,Wnt5a阳性细胞数量多于模型组(P<0.05)。与对照组相比,模型组大鼠软骨下骨板浅表区可见骨细胞陷窝,ESWT组股关节面损伤程度明显减轻(P<0.05)。ESWT诱导模型大鼠Wnt5a标记明显增加(P<0.05)。模型组Ⅰ型胶原和骨桥蛋白mRNA表达低于对照组,ESWT组Ⅰ型胶原和骨桥蛋白mRNA表达高于模型组(P<0.05)。模型组BMP2、VEGF和PCNA染色阳性细胞少于对照组,ESWT组BMP2、VEGF和PCNA染色阳性细胞多于模型组(P<0.05)。模型组CaMKⅡ、PLC、Wnt5a蛋白表达高于对照组,PKC蛋白表达高于对照组,ESWT组CaMKⅡ、PLC、Wnt5a蛋白表达低于模型组,PKC蛋白表达低于模型组(P<0.05)。结论体外冲击波治疗通过激活Wnt5a/Ca^(2+)信号通路促进大鼠股骨牵张成骨新生血管形成、细胞增殖和成骨生长因子的表达,改善骨力学性能和骨矿化加速。

关键词：股骨骨生成牵张体外冲击波疗法

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微线段齿轮系统动力学特性分析

振动与冲击 2018年第2期37卷 248-253页

作者：黄康汪涛合肥工业大学机械工程学院合肥230009

利用有限元法求出了微线段齿轮的时变啮合刚度,考虑微线段齿轮齿廓的特殊性,建立了单自由度微线段齿轮传动系统的动力学模型,模型中考虑了综合误差、时变啮合刚度以及齿侧间隙。通过数值仿真分析了比对两种齿轮系统在不同转速、载荷下... 详细信息

利用有限元法求出了微线段齿轮的时变啮合刚度,考虑微线段齿轮齿廓的特殊性,建立了单自由度微线段齿轮传动系统的动力学模型,模型中考虑了综合误差、时变啮合刚度以及齿侧间隙。通过数值仿真分析了比对两种齿轮系统在不同转速、载荷下的动力学响应,并指出了系统的亚谐共振及其幅值跳跃特性。对比分析了两种齿轮的分叉特性,结果表明,微线段齿轮相比普通渐开线齿轮具有更好的稳定性,其系统的混沌转速区间小,在中高速重载时其系统振动幅值小,传动更加平稳。

关键词：非线性动力学微线段齿轮分叉混沌

MouseVenue3D:A Markerless Three-Dimension Behavioral Tracking System for Matching Two-Photon Brain Imaging in Free-Moving Mice

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Neuroscience Bulletin 2022年第3期38卷 303-317页

作者： Yaning Han kang huang Ke Chen Hongli Pan Furong Ju Yueyue Long Gao Gao Runlong Wu Aimin Wang Liping Wang Pengfei Wei Shenzhen Key Laboratory of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science Guangdong Provincial Key Laboratory of Brain Connectome and BehaviorCAS Center for Excellence in Brain Science and Intelligence TechnologyBrain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen-Hong Kong Institute of Brain ScienceShenzhen Fundamental Research InstitutionsShenzhen518055China University of Chinese Academy of Sciences Beijing100049China University of Rochester RochesterNY14627USA Honam University Gwangju62399South Korea State Key Laboratory of Membrane Biology Institute of Molecular MedicinePeking UniversityBeijing100101China Department of Electronics Peking UniversityBeijing100871China State Key Laboratory of Advanced Optical Communication Systems and Networks Peking UniversityBeijing100101China

Understanding the connection between brain and behavior in animals requires precise monitoring of their behaviors in three-dimensional(3-D)***,there is no available three-dimensional behavior capture system that focuses on ***,we present MouseVenue3D,an automated and low-cost system for the efficient capture of 3-D skeleton trajectories in markerless *** improved the most time-consuming step in 3-D behavior capturing by developing an automatic calibration ***,we validated this process in behavior recognition tasks,and showed that 3-D behavioral data achieved higher accuracy than 2-D ***,MouseVenue3D was combined with fast high-resolution miniature two-photon microscopy for synchronous neural recording and behavioral tracking in the freely-moving ***,we successfully decoded spontaneous neuronal activity from the 3-D behavior of *** findings reveal that subtle,spontaneous behavior modules are strongly correlated with spontaneous neuronal activity patterns.

关键词： Computational neuroethology Behavioral and neural recording 3-D pose estimation Multi-view cameras Automatic calibration

Hydrogel-Assisted Electrokinetics for High-Resolution and Non-invasive Flow Monitoring in Microfluidic Chips

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Chinese Journal of Chemistry 2024年第6期42卷 571-577页

作者： Na Zhao Yanni Ma Zehua Yu Jun huang Xiangqian Fu Tao Qiu kang Liu MOE Key Laboratory of Hydraulic Machinery Transients School of Power and Mechanical EngineeringWuhan UniversityWuhanHubei430072 China Department of Urology Renmin Hospital of Wuhan UniversityWuhanHubei430072 China Department of Organ Transplantation Renmin Hospital of Wuhan UniversityWuhanHubei430072 China

Convenient non-invasive flow monitoring would facilitate the operation and control in microfluidic chips,but is challenging due to the small space of microchannels and complex operation required in traditional optical *** this work,we propose a novel non-invasive strategy to probe microfluidic flows via streaming potential *** sealing one side of the microchannel with a piece of hydrogel film,streaming potential inside the channel can be clearly detected by electrodes at outer surface of the hydrogel due to ion diffusion in the *** is detected without sensors contacting with the internal ***,the electrodes shape like a tiny probe,which can move around mapping the flow distribution in a chip with the spatial resolution of 1 mm and flow rate detection limit of 3μL·min–*** inside the channels can also be detected,due to the fluctuation of streaming voltage when gas-liquid interface flows through the electrode,showing an easy and potential way for multi-functional flow monitoring in microfluidic chips.

关键词： Microfluidics Hydrogels Electrokinetics Flow monitoring Non-invasive Sensor Charge transport