Hydrogel-Assisted Electrokinetics for High-Resolution and Non-invasive Flow Monitoring in Microfluidic Chips

作     者：Na Zhao Yanni Ma Zehua Yu Jun Huang Xiangqian Fu Tao Qiu Kang Liu Na Zhao;Yanni Ma;Zehua Yu;Jun Huang;Xiangqian Fu;Tao Qiu;Kang Liu

作者机构：MOE Key Laboratory of Hydraulic Machinery TransientsSchool of Power and Mechanical EngineeringWuhan UniversityWuhanHubei430072 China Department of UrologyRenmin Hospital of Wuhan UniversityWuhanHubei430072 China Department of Organ TransplantationRenmin Hospital of Wuhan UniversityWuhanHubei430072 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2024年第42卷第6期

页      面：571-577页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.51976141 52006123 62161160311) 

主　　题：Microfluidics Hydrogels Electrokinetics Flow monitoring Non-invasive Sensor Charge transport 

摘      要：Convenient non-invasive flow monitoring would facilitate the operation and control in microfluidic chips,but is challenging due to the small space of microchannels and complex operation required in traditional optical *** this work,we propose a novel non-invasive strategy to probe microfluidic flows via streaming potential *** sealing one side of the microchannel with a piece of hydrogel film,streaming potential inside the channel can be clearly detected by electrodes at outer surface of the hydrogel due to ion diffusion in the *** is detected without sensors contacting with the internal ***,the electrodes shape like a tiny probe,which can move around mapping the flow distribution in a chip with the spatial resolution of 1 mm and flow rate detection limit of 3μL·min–*** inside the channels can also be detected,due to the fluctuation of streaming voltage when gas-liquid interface flows through the electrode,showing an easy and potential way for multi-functional flow monitoring in microfluidic chips.