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Differential bonding behaviors of sodium/potassium-ion storage in sawdust waste carbon derivatives

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Chinese Chemical Letters 2024年第4期35卷 496-501页

作者： Jun-Ming Cao kai-Yang Zhang Jia-lin Yang Zhen-Yi Gu Xing-Long Wu MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun 130024China Department of Chemistry Northeast Normal UniversityChangchun 130024China

Sodium-ion batteries(SIBs) and potassium-ion batteries(PIBs) are the most promising alternatives to lithium-ion batteries, and thus have drawn intensive research attention. Porous carbon materials from different precursors have been widely used as anode materials owing to their compatible storage effectiveness of both larger radii sodium and potassium ions. However, the differential bonding behaviors of Na and K ions with porous carbon-based anode are the significant one worth investigating, which could provide a clean picture of alkali ions storage mechanism. Therefore, in this work, we prepare a porous carbon network derived from sawdust(SDC) wastes, to further analyze the differences on sodium and potassium ions storage behaviors in terms of bond-forming process. It is found that, as-prepared SDC anodes could deliver stable sodium and potassium storage capacities, however, there are notable distinctions in terms of electrochemical behaviors and diffusion processes. By virtue of ex-situ XRD and Raman spectroscopy, the phase transition reaction of potassium ions could be well-observed, and the results shows that the multiple intercalated compounds was formed in SDC network during ions insertion, further resulting in slower diffusion kinetics and larger resistance compared to non-bonded process of sodium ions storage. This study provides more insights into the differences between sodium and potassium ions storage, as well as the energy storage mechanism of porous carbon as anodes for secondary batteries.

关键词： Porous carbon Sodium-ion storage Potassium-ion storage Bonding behaviors Batteries

Development of a magnetite-gene complex for gene transfection

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Frontiers of Medicine 2010年第2期4卷 241-246页

作者： Jian XIN Yan LUO Ze-Feng XIA kai-Xiong TAO kai-lin CAI Gao-Xiong HAN Xiao-Ming SHUAI Ji-Liang WANG Han-Song DU Guo-Bin WANG Department of Laparoscopic Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Ophthalmology Wuhan No.1 HospitalWuhan 430022China

The key to successful gene therapy is toﬁnd a suitable method and carrier for transfection to allow a gene to be transferred into a cell and integrated into the target *** aim of this study was to determine whether biomagnetic material could be combined with the nucleic acid for gene ***-coated iron oxide nanoparticles(DCIONPs)were prepared and mixed with the plasmid pGenesil-1 containing the test gene,which expresses enhanced greenﬂuorescent protein(eGFP).PGenesil-1 empty vector was used as a *** binding ability was assessed by electrophoresis of the DNA on agarose gels and quantiﬁcation using BANDS-CAN *** different gene carriers,Lipofecta-mine 2000,Sofast,and DCIONPs,the large intestine cancer(Lovo)cell line was transfected in vitro with or without a magneticﬁ*** expression of eGFP was observed byﬂuorescence microscopy,and the transfection efﬁciency was *** results showed there was a rapid increase in combining rate when the quality ratio of DCIONPs and pGenesil-1 ascended from 1∶1 to 5∶***,the combining rate increased less rapidly as the quality ratio continued *** expression of eGFP showed that the early transfection rate could be improved by applying a magneticﬁ*** conclusion,the DCIONPs we synthesized are able to carry plasmid DNA and enhance the early transfection efﬁciency when using a magneticﬁeld.

关键词： nanoparticle magnetite gene therapy mag-netofection

Microstructure and Mechanical Behavior of Mg-Based Bimetal Plates with High Formability Sleeve by Co-extrusion

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Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 499-512页

作者： Yue-Hui Dang Sheng-lin Liu Xiao-Lei Ai Xiao-Wei Feng Bo Feng Zhuo Tian Ying-Fei lin Huan-Tao Chen kai-Hong Zheng School of Materials Science and Engineering Chang’an UniversityShaanxi 710064China Guangdong Key Laboratory of Metal Toughening Technology and Application Institute of New MaterialsGuangdong Academy of SciencesGuangzhou 510650China

In this study,microstructure and mechanical behavior of two types of Mg-based bimetal plates with a high formability sleeve were systematically studied,with a great emphasis on the effect of the interface characteristic and the sleeve fraction on the plasticity of composite *** rule of mixtures(ROM)for elongation was also *** results show that when there is no or thin diffusion layer with thickness of about 3μm,Mg-based bimetal plates have a good plasticity with elongation of about 19-24%,and the ROM predicted elongations are very close to the experimental *** contrast,with a diffusion layer about 95-155μm thick,Mg-based bimetal plates exhibit a poor plasticity with elongation of about 11-17%,and the experimental elongations largely deviate from the ROM *** plasticity of Mg-based bimetal plates increases with increasing sleeve *** study provides new insights on the plastic deformation of Mg-based bimetal composites with a high formability sleeve.

关键词： Mg-based composites Co-extrusion Microstructure Mechanical behavior Plastic deformation

Diagnostic accuracy of transient elastography (Fibro Scan) in detection of esophageal varices in patients with cirrhosis: A meta-analysis

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World Journal of Gastroenterology 2017年第2期23卷 345-356页

作者： Ke Pu Jing-Hong Shi Xu Wang Qian Tang Xin-Jie Wang kai-lin Tang Zhong-Qi Long Xing-Sheng Hu School of Clinical Medicine Dazhou College of Chinese Medicine Department of Immunology Shaanxi University of Chinese Medicine Department of Hepatobiliary Surgery Dachuan Southern Hospital School of Nursing Georgia Southern University School of Life Science Northwest University General Surgery Department of Jinshan Hospital The First Affiliated Hospital of Chongqing Medical University Department of Oncology Nanchong Central Hospital(The Second Affiliated Hospital of North Sichuan Medical College)

AIM To investigate the diagnostic accuracy of Fibro Scan(FS) in detecting esophageal varices(EV) in cirrhotic *** Through a systemic literature search of multiple databases, we reviewed 15 studies using endoscopy as a reference standard, with the data necessary to calculate pooled sensitivity(SEN) and specificity(SPE), positive and negative LR, diagnostic odds ratio(DOR) and area under receiver operating characteristics(AUROC). The quality of the studies was rated by the Quality Assessment of Diagnostic Accuracy studies-2 tool. Clinical utility of FS for EV was evaluated by a Fagan plot. Heterogeneity was explored using meta-regression and subgroup analysis. All statistical analyses were conducted via Stata12.0, MetaD isc1.4 and RevM *** In 15 studies(n = 2697), FS detected the presence of EV with the summary sensitivities of 84%(95%CI: 81.0%-86.0%), specificities of 62%(95%CI: 58.0%-66.0%), a positive LR of 2.3(95%CI: 1.81-2.94), a negative LR of 0.26(95%CI: 0.19-0.35), a DOR of 9.33(95%CI: 5.84-14.92) and an AUROC of 0.8262. FS diagnosed the presence of large EV with the pooled SEN of 0.78(95%CI: 75.0%-81.0%), SPE of 0.76(95%CI: 73.0%-78.0%), a positive and negative LR of 3.03(95%CI: 2.38-3.86) and 0.30(95%CI: 0.23-0.39) respectively, a summary diagnostic OR of 10.69(95%CI: 6.81-16.78), and an AUROC of 0.8321. A meta-regression and subgroup analysis indicated different etiology could serve as a potential source of heterogeneity in the diagnosis of the presence of EV group. A Deek's funnel plot suggested a low probability for publication *** Using FS to measure liver stiffness cannot provide high accuracy for the size of EV due to the various cutoff and different etiologies. These limitations preclude widespread use in clinical practice at this time; therefore, the results should be interpreted cautiously given its SEN and SPE.

关键词： Transient elastography FibroScan Liver cirrhosis Meta-analysis Esophageal varices

Six2 is negatively correlated with prognosis and facilitates epithelial-mesenchymal transition via TGF-β/Smad signal pathway in hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2019年第6期18卷 525-531页

作者： Zheng-Hua Wan Yun-Han Ma Tian-Yi Jiang Yun-kai lin Yuan-Yuan Shi Ye-Xiong Tan Li-Wei Dong Hong-Yang Wang International Cooperation Laboratory on Signal Transduction Eastern Hepatobiliary Surgery InstituteThe Second Military Medical UniversityShanghai 200438China National Center for Liver Cancer The Second Military Medical UniversityShanghai 201805China No.971 Hospital of Peoples’Liberation Army Navy Qingdao 266071China State Key Laboratory of Oncogenes and related Genes Shanghai Cancer InstituteRenji HospitalShanghai Jiaotong University School of MedicineShanghai 200127China

Background: Increasing evidence indicates that Six2 contributes to tumorigenesis in various tumor in- cluding hepatocellular carcinoma (HCC). This study aimed to determine the role of Six2 in HCC and to elucidate the association of Six2 with clinical pathological characteristics. Methods: The expressions of Six2 in HCC tumor, para-tumor tissue and portal vein tumor thrombus (PVTT) were detected by tissue microarray technique, immunohistochemistry, real-time RT-PCR and West- ern blotting. Chi-square and Kaplan-Meier analysis were used to analyze the correlation between Six2 expression and prognosis of HCC patients. Lentivirus mediated Six2 knockdown, spheroid formation as- say, proliferation assay and subcutaneous tumor implantation were performed to determine the function of Six2. Results: In 274 HCC samples, Six2 was strongly expressed. Kaplan-Meier analysis revealed that high ex- pression of Six2 was correlated with a shorter overall survival (OS) and disease-free survival (DFS). More- over, Six2 expression was associated with sex, alpha-fetoprotein, tumor size and portal vein invasion. Six2 was highly expressed in PVTT. Six2 knockdown inhibited HCC cell lines proliferation, migration, and self-renewal in vitro and in vivo. In addition, low-expression of Six2 weakened TGF-β induced Smad4 activation and epithelial-mesenchymal transition in HCC cell lines. Conclusions: Elevated Six2 expression in HCC tumor patients was associated with negative prognosis. Upregulated Six2 promoted tumor growth and facilitated HCC metastasis via TGF-β/Smad signal pathway.

关键词： Hepatocellular carcinoma Six2 Prognosis Metastasis

Identification of biomarkers for hepatocellular carcinoma by semiquantitative immunocytochemistry

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World Journal of Gastroenterology 2014年第19期20卷 5826-5838页

作者： Hong Mu kai-Xuan lin Hong Zhao Shu Xing Cong Li Fang Liu Hai-Zhen Lu Ze Zhang Yu-lin Sun Xi-Yun Yan Jian-Qiang Cai Xiao-Hang Zhao State Key Laboratory of Molecular Oncology Cancer Institute HospitalChinese Academy of Medical Sciences and Peking Union Medical College Center of Basic Medical Sciences Navy General Hospital of Chinese PLA Department of Abdominal Surgery Cancer Institute HospitalChinese Academy of Medical Science and Peking Union Medical College Key Laboratory of Protein and Peptide Pharmaceutical National Laboratory of BiomacromoleculesInstitute of BiophysicsChinese Academy of Sciences Department of Pathology Cancer Institute HospitalChinese Academy of Medical Sciences and Peking Union Medical College

AIM: To investigate the expression of key biomarkers in hepatoma cell lines, tumor cells from patients’ blood samples, and tumor tissues.

关键词： Hepatocellular carcinoma Biomarker Immunocytochemistry Semiquantitative analysis Three-dimensional reconstruction

国家文化数字化下乡村文化旅游产业发展——以西安市鄂邑区黄河流域乡村为例

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西安交通工程学院学术研究 2024年第1期9卷 103-107页

作者：薛凯琳乔佳西安交通工程学院陕西西安710300

党的二十大报告对于加快建设数字中国、实施国家文化数字化战略作出了重要部署,明确提出"加快发展数字经济,促进数字经济和实体经济深度融合"乡村旅游是促进民营经济和县域经济突破和发展的关键,也是推动产业结构调整和转型升级的关键... 详细信息

党的二十大报告对于加快建设数字中国、实施国家文化数字化战略作出了重要部署,明确提出"加快发展数字经济,促进数字经济和实体经济深度融合"乡村旅游是促进民营经济和县域经济突破和发展的关键,也是推动产业结构调整和转型升级的关键。并且社会各界对黄河流域治理的关注度较大,在产学研界关于黄河治理的研究成果丰硕,并且黄河流域附近村庄的治理改进从产业兴旺、文化传承、生态修复、乡村治理等不同视角对黄河流域的乡村振兴进行了大量的理论研究,为本项目的研究和开展实施打下了良好的理论支撑。但是,与东部地区相比,西部地区的乡村文化旅游在发展过程中尚存在一系列的问题仍然存在一些问题还未解决。党的十九届六中全会提出,要通过发展工业来促进农村经济的发展,让农民过上更好的生活。因此,在黄河流域治理和乡村振兴战略要求下,研究探讨西安市鄂邑区在文旅产业融合发展方面存在的主要问题,并提出有针对性的意见和建议,对促进文旅产业高质量发展具有重要的意义。

关键词：数字中国黄河流域治理文旅融合乡村振兴高质量发展乡村创客之家

我国儿童奶酪食品现状及挑战:奶酪营养与儿童健康

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乳业科学与技术 2024年第3期47卷 41-48页

作者：郝欣悦邹俊哲刘靓任静林凯易华西张兰威公丕民中国海洋大学食品科学与工程学院山东青岛266000 内蒙古国家乳业技术创新中心内蒙古呼和浩特150100

随着我国的发展,儿童奶酪逐渐受到乳业的重视,成为我国乳业发展的新增长点。但是当前市场上儿童奶酪质量良莠不齐,不能完全根据儿童营养需求进行营养强化,风味相似,卖点雷同,引起大众的感官疲劳,同时也与消费者对清洁标签的追求背道而驰... 详细信息

随着我国的发展,儿童奶酪逐渐受到乳业的重视,成为我国乳业发展的新增长点。但是当前市场上儿童奶酪质量良莠不齐,不能完全根据儿童营养需求进行营养强化,风味相似,卖点雷同,引起大众的感官疲劳,同时也与消费者对清洁标签的追求背道而驰,儿童奶酪行业的发展面临新的挑战。本文从儿童健康和奶酪营养角度出发,将不同年龄段儿童对营养风味与质构的需求与奶酪的营养、风味和质构相联系,综述我国儿童奶酪食品的现状、挑战及可能的发展方向。

关键词：儿童奶酪营养健康需求风味质构

抽水蓄能机组水轮机工况启动过程内部流场分析

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大电机技术 2024年第1期 1-7页

作者：杨小龙王焕茂林恺靳发业雷兴春毕慧丽罗永要南方电网储能股份有限公司广州510630 水力发电设备全国重点实验室(哈尔滨电机厂有限责任公司) 哈尔滨150040 哈尔滨电机厂有限责任公司哈尔滨150040 哈尔滨大电机研究所哈尔滨150040 水圈科学与水利工程全国重点实验室(清华大学) 北京100084 清华大学能源与动力工程系北京100084

本文采用CFD数值模拟的方法,模拟计算了抽水蓄能机组在水轮机工况启动过程内部流场特征。得到了在活动导叶开启过程中的速度、压力随时间的瞬态分布规律,讨论了蓄能机组开启过程中外特性的变化曲线。结果表明:活动导叶的开启规律可以大... 详细信息

本文采用CFD数值模拟的方法,模拟计算了抽水蓄能机组在水轮机工况启动过程内部流场特征。得到了在活动导叶开启过程中的速度、压力随时间的瞬态分布规律,讨论了蓄能机组开启过程中外特性的变化曲线。结果表明:活动导叶的开启规律可以大体分为五个阶段。活动导叶的开启规律是先缓慢开启,然后以较快的速度关闭,最后再保持到空载的开度,从第四阶段,导叶再逐渐打开直到额定开度。转轮扭矩和机组流量呈现出先增大后减小的趋势,当导叶逐渐打开时,转轮扭矩和机组流量再逐渐上升。本文为研究蓄能机组水轮机工况下启动过程的内部流动变化提供了参考依据,同时对提高水轮机工况的启动稳定性具有重要意义。

关键词：抽水蓄能机组数值模拟水轮机工况导叶开启外特性曲线内部流场分析

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