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Field Trial of 40 Gbit/s ETDM Prototype System over 219 km of Installed Single Mode Fiber

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光学学报 2003年第S1期23卷 659-660页

作者： Sang Soo Lee Hyun Woo Cho Sang Kyu Lim Ki Ho han Jin Soo han Moo jung Chu Je Soo Ko Kyeong-Mo yoon Yong-Gi Lee Optical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Communication Department Electronics and Telecommunications Research Institute Deajeon KoreaOptical Transmission Research Team Technical Laboratory KT Deajeon KoreaOptical Transmission Research Team Technical Laboratory KT Deajeon Korea

Transmission of 40Gbit/s NRZ signal was successfully demonstrated over 219km of installed SMF in KT's Daejeon area network. After transmission, the measured power penalty was 0.5dB for all the tributary channels.

关键词： of ET be over Field Trial of 40 Gbit/s ETDM Prototype System over 219 km of Installed Single Mode Fiber

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Peroral endoscopic myotomy for treatment of Guillain-Barre syndrome-associated achalasia: A rare case

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World Journal of Gastroenterology 2017年第5期23卷 926-930页

作者： Seung Kak Shin Kyoung Oh Kim Eui Joo Kim Su Young Kim jung Ho Kim yoon Jae Kim Jun-Won Chung Kwang An Kwon Dong Kyun park Department of Internal Medicine Gachon University Gil Medical CenterIncheon 21565South Korea

Guillain-Barre syndrome (GBS)-associated achalasia is a very rare disease of uncertain cause. We report the case of a patient diagnosed with GBS-associated type I achalasia who was successfully treated with peroral endoscopic myotomy (POEM). A 30-year-old man who was diagnosed with GBS 3 mo before was referred to our department with dysphagia and meal-related regurgitation. The results of esophagography, endoscopy, and high-resolution manometry (HRM) revealed type I achalasia. POEM that utilized a submucosal tunneling technique was performed to treat the GBS-associated type I achalasia. After POEM, smooth passage of a contrast agent into the stomach was shown in follow-up esophagography, and follow-up HRM revealed a decrease in the mean integrated relaxation pressure 22.9 mmHg to 9.6 mmHg. The patient remained without dysphagia for 7 mo, even though the patient’s neurological problems were not fully resolved. POEM may be a safe and effective treatment for GBS-associated type I achalasia.

关键词： Peroral endoscopic myotomy Achalasia Guillain-Barre syndrome

Scalp electroacupuncture at the Baihui acupoint (DU 20) improves functional recovery in rats with cerebral ischemia Association with increased expression of vascular endothelial growth factors

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Neural Regeneration Research 2011年第36期6卷 2822-2828页

作者： Min-Wook Kim You Chul Chung Hee Chan jung Moon-Seo park Young-Min han Yong-An Chung Lee-So Maeng Sang-In park Jiyeon Lim Seung Chan Kim Woo-Seok Im Jin Young Chung Minky Kim Manho Kim Institute of Catholic Integrative Medicine (ICIM) Incheon St. Mary’s Hospital Catholic University of Korea Incheon Korea Department of Rehabilitation Medicine Catholic University of Korea Seoul Korea Department of Neurology Seoul National University Hospital SNUMRC Seoul Korea Department of Biotechnology Yonsei University Seoul Korea Department of Neurology Seoul Medical Center Seoul Korea

In this study, we induced cerebral infarction in rats by occluding the right middle cerebral artery, and tested the effects of electroacupuncture at the Baihui acupoint （DU 20）. Motor and sensory function was tested using Garcia’s scale and motor weakness grading, and the expression of vascular endothelial growth factor in the brain was quantified using immunoblotting and immunohistochemistry. We found that scalp electroacupuncture at DU 20 significantly improved motor performance and sensory function in rats with stroke, and this was accompanied by an increased expression of vascular endothelial growth factor in the ischemic brain tissue and peri-ischemic area. In addition, Pearson correlation analysis showed that the improvements in functional recovery were correlated with the increased expression of vascular endothelial growth factor.

关键词： electroacupuncture cerebrovascular disorder vascular endothelial growth factor Baihui acupoint functional improvement

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Defect engineering of ternary Cu-In-Se quantum dots for boosting photoelectrochemical hydrogen generation

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Carbon Energy 2023年第12期5卷 215-228页

作者： Shi Li Sung-Mok jung Wookjin Chung Joo-Won Seo Hwapyong Kim Soo Ik park Hyo Cheol Lee Ji Su han Seung Beom Ha In Young Kim Su-Il In Jae-Yup Kim Jiwoong Yang Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Chemical Engineering Dankook UniversityYonginRepublic of Korea Department of Chemistry and Nanoscience College of Natural ScienceEwha Womans UniversitySeoulRepublic of Korea Energy Science and Engineering Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea

Heavy-metal-free ternary Cu–In–Se quantum dots(CISe QDs)are promising for solar fuel production because of their low toxicity,tunable band gap,and high light absorption *** defects significantly affect the photophysical properties of QDs,the influence on photoelectrochemical hydrogen production is not well ***,we present the defect engineering of CISe QDs for efficient solar-energy *** acid–base reactions between metal halide–oleylamine complexes and oleylammonium selenocarbamate are modulated to achieve CISe QDs with the controlled amount of Cu vacancies without changing their *** them,CISe QDs with In/Cu=1.55 show the most outstanding photoelectrochemical hydrogen generation with excellent photocurrent density of up to 10.7 mA cm-2(at 0.6 VRHE),attributed to the suitable electronic band structures and enhanced carrier concentrations/lifetimes of the *** proposed method,which can effectively control the defects in heavy-metal-free ternary QDs,offers a deeper understanding of the effects of the defects and provides a practical approach to enhance photoelectrochemical hydrogen generation.

关键词： copper-indium-selenide defect engineering photoelectrochemical hydrogen generation quantum dots solar hydrogen

Surgical failure after colonic stenting as a bridge to surgery

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World Journal of Gastroenterology 2014年第33期20卷 11826-11834页

作者： jung Ho Kim Kwang An Kwon Jong Joon Lee Won-Suk Lee Jeong-Heum Baek yoon Jae Kim Jun-Won Chung Kyoung Oh Kim Dong Kyun park Ju Hyun Kim Department of Internal Medicine Gachon University Gil Medical Center Incheon 405760 South Korea Department of Surgery Gachon University Gil Medical Center Incheon 405760 South Korea

AIM: To identify risk factors for surgical failure after colonic stenting as a bridge to surgery in left-sided malignant colonic obstruction.

关键词： Colorectal neoplasms Endoscopy Intesti-nal obstruction Risk factors Stents

Changes in smoking behavior and adherence to preventive guidelines among smokers after a heart attack

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Journal of Geriatric Cardiology 2013年第2期10卷 146-150页

作者： yoon-jung Choi Jong-Seon park Ung Kim Sang-Hee Lee Jang-Won Son Dong-Gu Shin Young-Jo Kim Myung-Ho Jeong Young-Keun Ahn Myeong-Chan Cho Jang-Whan Bae Chong-Jin Kim Jin-Man Cho Kyoo-Rok han Jun-Hee Lee Divison of Cardiology Department of Internal Medicine Yeungnam University Hospital 170 Hyeonchung-ro Nam-gu Daegu 705-717 South Korea Division of Cardiology Department of Internal Medicine Chonnam National University Hospital 42 Jebong-ro Dong-gu Kwangju 501-757 South Korea Divison of Cardiology Department of Internal Medicine Chungbuk National University Hospital 410 Sungbong-ro Heungdeok-gu Cheongju Chungcheongbuk-do 361-711 South Korea Division of Cardiology Department of Internal Medicine Kyunghee University Hospital 892 Dongnam-ro Gandong-gu Seoul 134-727 South Korea Division of Cardiology Department of Internal Medicine Hanrim University Hospital 94-195 Yeongdeungpo-dong Yeongdeungpo-gu Seoul 150-030 South Korea

Objective Risk factor modification is key to preventing subsequent cardiac events after a heart attack. This study was designed to investigate the disparity between preventive guidelines and clinical practice among smoking patients. Methods The study was carried out in smokers admitted with myocardial infarction (MI). Atotal of 275 patients who had been regularly followed for over one year after MI were randomly selected and enrolled in this *** investigated changes in smoking behavior and the adherence rate to ACC/AHA Guidelines for secondary prevention in patients with coronary artery disease at the time of, and one year after, the index event. Results The study population consisted of 275 patients (97.1% males) with a mean age of 57.0 ±11.2 years. Achievement of target goals at one year was as follows: smoking cessation, 52.3%; blood pressure, 83.9%; HbA1c, 32.7%; lipid profile, 65.5%; and body mass index (BMI), 50.6%. Over one year, 80% of the patients attempted to quit smoking; 27% of them re-started smoking within one month after discharge while 65% succeeded in cessation of smoking. At one year, only 52% of the patients overall had stopped smoking. From the multivariate logistic analysis including smoking patterns and clinical characteristics, the severity of coronary artery disease was the only independent predictor for smoking cessation (Relative risk (RR): 1.230; P = 0.022). Conclusions Only a small percentage of MI patients adhere to guidelines for secondary prevention and a sizable proportion fail to stop smoking. These findings underscore the need for an effective patient education system.

关键词： Coronary artery disease Myocardial infarction Prevention Smoking

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Je-Chun-Jun induced apoptosis of human cervical carcinoma HeLa cells

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Acta Pharmacologica Sinica 2004年第10期 132-139页

作者： han-jung CHAE,Kyung-mi park,Geun-youn LEE,Gi-seup JEONG,Hyung-rae park,Hyung-min KIM,Soo-wan CHAE,Shim-keun YOO,Hyung-ryong KIM Department of Pharmacology and the Institute of Cardiovascular Research School of Medicine Chonbuk National University Jeonju Chonbuk 464-701 South Korea Department of Gynecology School of Oriental Medicine Wonkwang University Iksan Chonbuk 470-739 South Korea Department of Dental Pharmacology and Nano-Science & Technology Research Institute School of Dentistry Wonkwang University Iksan Chonbuk 570-749 South Korea Department of Dental Pharmacology and Nano-Science & Technology Research Institute School of Dentistry Wonkwang University Iksan Chonbuk 570-749 South Korea Department of Dental Pharmacology and Nano-Science & Technology Research Institute School of Dentistry Wonkwang University Iksan Chonbuk 570-749 South Korea Department of Pharmacology College of Oriental Medicine Kyung Hee University Seoul South Korea Department of Pharmacology and the Institute of Cardiovascular Research School of Medicine Chonbuk National University Jeonju Chonbuk 464-701 South Korea Department of Gynecology School of Oriental Medicine Wonkwang University Iksan Chonbuk 470-739 South Korea Department of Dental Pharmacology and Nano-Science & Technology Research Institute School of Dentistry Wonkwang University Iksan Chonbuk 570-749 South Korea

AIM: To study the mechanism of Je-Chun-Jun (JCJ)-inducing the apoptosis of the human cervical carcinoma, HeLa cells. METHODS: The cell viability was assessed using MTT assay. The optical density was measured at 570 nm. The caspase activity was measured using 50 mmol/L of fluorogenic substrate, AC-DEVD-AMC (caspase-3), AC-VEID-AMC (caspase-8) or AC-LEHD-AFC (caspase-9). To confirm the expression of proteins, Western blotting was performed. To detect the characteristic of apoptosis chromatin condensation, HeLa cells were stained with Hoechst 33258 in the presence of JCJ. For the cell cycle analysis, HeLa cells were incubated with Propidium iodide (PI) solution. Fluorescence intensity of cell cycle was measured using flow cytometry system. RESULTS: The loss of viability occurred following the exposure of 10 g/L JCJ. Cells treated with 10 g/L JCJ for 3 d exhibited the apoptotic morphology (brightly blue-fluorescent condensed nuclei by Hoechst 33258-staining) and the reduction of cell volume. Cells incubated

关键词： herbal medicine apoptosis p38 MAPK HeLa cells

Clinical outcomes and predictive factors in oral corticosteroid-refractory active ulcerative colitis

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World Journal of Gastroenterology 2013年第2期19卷 265-273页

作者： han Ho Jeon Hyun jung Lee Hui Won Jang Jin Young yoon yoon Suk jung Soo jung park Sung Pil Hong Tae Il Kim Won Ho Kim Jae Hee Cheon Department of Internal Medicine Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea Brain Korea 21 Project for Medical Science Yonsei University College of MedicineSeoul 120-752South Korea

AIM:To evaluate the clinical outcomes and prognostic factors after intravenous corticosteroids following oral corticosteroid failure in active ulcerative colitis ***:Consecutive patients with moderate to severe ulcerative colitis who had been treated with a course of intravenous corticosteroids after oral corticosteroid therapy failure between January 1996 and July 2010 were recruited at Severance Hospital,Seoul,South *** disease activity was measured by the Mayo score,which consists of stool frequency,rectal bleeding,mucosal appearance at flexible sigmoidoscopy,and Physician Global *** retrospectively evaluated clinical outcomes at two weeks,one month,three months,and one year after the initiation of intravenous corticosteroid *** weeks outcomes were classified as responders or *** month,three month and one year outcomes were classified into prolonged response,steroid dependency,and ***:Our study included a total of 67 eligible *** two weeks,56(83.6%) patients responded to intravenous *** one month,complete remission was documented in 18(32.1%) patients and partial remission in 26(46.4%).Eleven patients(19.7%) were refractory to the *** three months and one year,we found 37(67.3%) and 25(46.3%) patients in prolonged response,ten(18.2%) and 23(42.6%) patients in corticosteroid dependency,8(14.5%) and 6(11.1%) patients with no response,*** 9 patients were underwent elective proctocolectomy within 1 *** duration of oral corticosteroid therapy(> 14 d vs ≤ 14 d,P = 0.049) and lower hemoglobin level(≤ 11.0 mg/dL vs >11.0 mg/dL,P = 0.02) were found to be poor prognostic factors for response at two *** one year outcome,univariate analysis revealed that only a partial Mayo score(≥ 6 vs <6,P = 0.057) was found to be associated with a poor ***:The duration of oral corticosteroid therapy and lower hemoglobin level were strongly associ

关键词： Clinical outcome Prognosis Corticosteroid Ulcerative colitis

Effect of Hoechunyangkyeok-San Extract on Melanogenesis

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Journal of Cosmetics, Dermatological Sciences and Applications 2016年第3期6卷 85-95页

作者： Mi Jin Kim Taek Kyu jung Hyun-Chul park Kyung-Sup yoon Skin Science R&D Center Saimdang Cosmetics Co. Ltd. Cheongju-si South Korea

Forsythia fructus has been shown to have antioxidative, anti-inflammatory, antibacterial, anti-aging and whitening effects. Hoechunyangkyeok-san (Forsythia viridissima-prescription) is a traditional herbal medicine, which has been clinically used for treating febrile and inflammatory disorders. This work was carried out to investigate the skin whitening effects of Forsythia viridissima-prescription extract (a hydrolyzed extract of Hoechunyangkyeok-san: SID White HYC) on skin. The effects of SID White HYC were assessed the melanin contents in B161 melanoma cells and the pigmented equivalent with HMB45 and Fontana Masson staining in 3D skin model. Then, we examined the expression of major pigment enzymes regulating melanin synthesis and melanosome transport related proteins in B16F1 cells. SID White HYC significantly inhibited the melanin synthesis (56.7% and 30.6% inhibition at 100 μg/mL, intracellular and secreted, respectively) in B16F1 cells and 3D skin model. In addition, western blotting analysis showed that SID White HYC reduced the expression of melanin synthesis and melanosome transport related proteins in B16F1 cells. In clinical trials, the cream containing 0.05% SID White HYC showed skin depigmentation effect without any irritation. These results suggest that SID White HYC may be useful inhibition of melanogenesis and melanosome transport. Therefore, SID White HYC may have potential as a skin-whitening ingredient in cosmetics.

关键词： Hoechunyangkyeok-San (Formula Extract Containing Forsythia viridissima Fruit Platycodon grandiflorum Root Glycyrrhiza glabra Root Paeonia japonica Root Angelica gigas Root Scutellaria baicalensis Root Gardenia jasminoides Fruit Coptis chinensis Root Mentha arvensis Leaf Rehmannia glutinosa Root Poncirus trifoliate Fruit) Melanogenesis Melanosome Transport Melanin Whitening