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New-onset diabetes after kidney transplantation:Incidence and associated factors

World Journal of Diabetes 2018年第7期9卷 132-137页

作者： Vania Gomes Florbela ferreira joséGuerra Maria Joao Bugalho Endocrinology Diabetes and Metabolism DepartmentSanta Maria HospitalLisbon 1649-035Portugal Nephrology and Kidney Transplantation Department Santa Maria HospitalLisbon 1649-035Portugal

AIM To determine the incidence and associated factors of new-onset diabetes after transplantation(NODAT) in a Portuguese central hospital. METHODS This single-center retrospective study involved consecutive adult nondiabetic transplant recipients, who had undergone kidney transplantation between January 2012 and March 2016. NODAT was diagnosed according to the criteria of the American Diabetes Association. Data were collected from an institutional database of the Nephrology and Kidney Transplantation Department(Santa Maria Hospital, Lisbon, Portugal) and augmented with data of laboratorial parameters collected from the corresponding patient electronic medical records. Exclusion criteria were preexisting diabetes mellitus, missing information and follow-up period of less than 12 mo. Data on demographic and clinical characteristics as well as anthropometric and laboratorial parameters were also collected. Patients were divided into two groups: With and without NODAT-for statistical *** A total of 156 patients received kidney transplantduring the study period, 125 of who were included in our analysis. NODAT was identified in 27.2% of the patients(n = 34; 53% female; mean age: 49.5 ± 10.8 years; median follow-up: 36.4 ± 2.5 mo). The incidence in the first year was 24.8%. The median time to diagnosis was 3.68 ± 5.7 mo after transplantation, and 76.5% of the patients developed NODAT in the first 3 mo. In the group that did not develop NODAT(n = 91), 47% were female, with mean age of 46.4 ± 13.5 years and median follow-up of 35.5 ± 1.6 mo. In the NODAT group, the pretransplant fasting plasma glucose(FPG) levels were significantly higher [101(96.1-105.7) mg/d L vs 92(91.4-95.8) mg/d L, P = 0.007] and pretransplant impaired fasting glucose(IFG) was significantly more frequent(51.5% vs 27.7%, P = 0.01). Higher pretransplant FPG levels and pretransplant IFG were found to be predictive risk factors for NODAT development [odds ratio(OR): 1.059, P = 0.003; OR: 2.77

关键词： New-onset diabetes after transplant Incidence Kidney transplantation Impaired fasting glucose Immunosuppression

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Effect of ECAP processing on distribution of second phase particles,hardness and electrical conductivity of Cu-0.81Cr-0.07Zr alloy

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Transactions of Nonferrous Metals Society of China 2022年第1期32卷 217-232页

作者： Filipe CALDATTO DALAN Gisele ferreira de LIMA ANDREANI Dilermando Nagle TRAVESSA Ilshat albertovich FAIZOV Svetlana FAIZOVA Kátia Regina cardoso Institute of Science and Technology Federal University of São Paulo330 Talim St.São Josédos Campos12231-280Brazil Institute for Metals Superplasticity Problems RAS 39 S.Khalturin St.Ufa450001Russia Ufa State Aviation Technical University 12 K.Marx St.Ufa450008Russia

The effect of equal-channel angular pressing(ECAP)processing at room temperature and 300℃on the distribution of the second phase particles and its influence on hardness and electrical conductivity of the commercial Cu-0.81Cr-0.07Zr alloy were *** characterization indicated that the area fraction of coarse Cr-rich particles decreased after ECAP *** reduction was attributed to the Cr dissolution induced by plastic *** electrical conductivity of the alloy decreased by 12%after 4 ECAP passes at room temperature due to the increase of electrons scattering caused by higher Cr content in solid solution and higher density of defects in the *** results were supported by the reduction of the Cu lattice parameter and by the exothermic reactions,during differential scanning calorimetry(DSC)analysis,observed only in the samples subjected to ECAP *** heat treatment after ECAP processing promoted an additional hardening effect and the complete recuperation of the electrical conductivity,caused by the re-precipitation of the partially dissolved *** better combination of hardness(191 HV)and electrical conductivity(83.5%(IACS))was obtained after 4 ECAP passes at room temperature and subsequent aging at 380℃for 1 h.

关键词： ECAP Cu-Cr-Zr alloy second phase particles phase transition

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An esophageal submucosal tumor treated with submucosal tunneling endoscopic resection:an unexpected result

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Gastroenterology Report 2021年第3期9卷 269-271,I0003页

作者： Ming-Yan Cai Mariana ferreira cardoso Yan Zhu Yun-Shi Zhong Ping-Hong Zhou Endoscopy Center Zhongshan HospitalFudan UniversityShanghaiP.R.China Gastroenterology Department Hospital Professor Doutor Fernando FonsecaAmadoraPortugal

Case presentation A 66-year-old female patient underwent esophagogastroduodenoscopy(EGD)in our center because of occasional dysphagia,and a large submucosal tumor(SMT)was identified 32–36cm from the incisors,occupying nearly half of the luminal circumference(Figure 1A).Mini-probe endoscopic ultrasonography(EUS)revealed a hypoechoic submucosal lesion,measuring 20×15mm and originating from the superficial muscularis propria layer(Figure 1B).It was covered by normal-appearing mucosa.

关键词：食管黏膜下肿瘤 superficial Figure

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Effect of Homogenizing Procedures on the Properties of Reaction Sialon Suspension

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厦门大学学报（自然科学版） 2002年第S1期41卷 132-133页

作者： Xavier Venceslau Kexin Chen josé M F ferreira Department of Ceramics and Glass Engineering CICECO University of AveiroDepartment of Ceramics and Glass EngineeringCICECO University of AveiroDepartment of Ceramics and Glass EngineeringCICECO University of Aveiro PortugalPortugalPortugal

Homogeneous, high concentrated ceramic suspensions wi th low viscosity are the key controlling factors for the production of ceramic c omponents through colloidal processing. A well-dispersed suspension can be obta ined by choosing suitable dispersant, solvent, particle size distribution etc. B esides these factors, the homogenizing procedure is also a key step. In this paper, reaction sialon suspensions were prepared using 3-wt% KD1 as dis persant in organic media composed of 60-vol% methyletheylketone and 40-vol% et hanol. Different homogenizing procedures have been used and compared, including planetary milling, low energy ball milling and ultrasonic disaggregation. The ef fects of different homogenizing routes and mixing times on the rheology and stab ility of suspensions, and on the microstructure of slip casting green bodies, ha ve been studied. The varying dispersion efficiencies observed could be attribute d to differences in deagglomeration degrees achieved and in adsorption amount of dispersant onto the surface of reaction sialon powders.

关键词： Effect of Homogenizing Procedures on the Properties of Reaction Sialon Suspension

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Application of data science in the prediction of solar energy for the Amazon basin:a study case

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Clean Energy 2023年第6期7卷 1344-1355页

作者： AndréLuis ferreira Marques Márcio joséTeixeira Felipe Valencia de Almeida Pedro Luiz Pizzigatti Corrêa Polytechnic School of the University of Sao Paulo Av.Prof.Luciano Gualberto380-ButantaSao Paulo-SP05508-010Brazil Institute of Physics of the University of Sao Paulo Brazil

The need for renewable energy sources has challenged most countries to comply with environmental protection actions and to handle climate *** energy figures as a natural option,despite its *** has a green energy matrix with significant expansion of solar form in recent *** preserve the Amazon basin,the use of solar energy can help communities and cities improve their living standards without new hydroelectric units or even to burn biomass,avoiding harsh environmental *** novelty of this work is using data science with machine-learning tools to predict the solar incidence(W.h/m^(2))in four cities in Amazonas state(north-west Brazil),using data from NASA satellites within the period of ***-tree-based models and vector autoregressive(time-series)models were used with three time aggregations:day,week and *** predictor model can aid in the economic assessment of solar energy in the Amazon basin and the use of satellite data was encouraged by the lack of data from ground *** mean absolute error was selected as the output indicator,with the lowest values obtained close to 0.20,from the adaptive boosting and light gradient boosting algorithms,in the same order of magnitude of similar references.

关键词： solar energy renewable energy Amazon basin machine learning time series data science decision-trees ensemble vector autoregression

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MYC and gastric adenocarcinoma carcinogenesis

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World Journal of Gastroenterology 2008年第39期14卷 5962-5968页

作者： Danielle Queiroz Calcagno Mariana ferreira Leal Paulo Pimentel Assumpo Marília de Arruda cardoso Smith Rommel Rodríguez Burbano Human Cytogenetics Laboratory Biology Science InstituteFederal University of ParáBelém PA 66075-900Brazil Genetics Division Department of Morphology and GeneticsFederal University of So PauloSo Paulo SP 04023-900Brazil Joo de Barros Barreto University Hospital Federal University of ParáBelém PA 66073-000Brazil

MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been described as a key element of several carcinogenesis processes in humans. Many studies have shown an association between MYC deregulation and gastric cancer. MYC deregulation is also seen in gastric preneoplastic lesions and thus it may have a role in early gastric carcinogenesis. Several studies have suggested that amplification is the main mechanism of MYC deregulation in gastric cancer. In the present review, we focus on the deregulation of the MYC oncogene in gastric adenocarcinoma carcinogenesis, including its association with Helicobacterpylori （Hpylon] and clinical applications.

关键词： MYC Gastric adenocarcinoma Gastric preneoplastic lesions Gastric carcinogenesis Helicobacter pylori

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Drying of pasty and granular materials in mechanically and conventional spouted beds

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Particuology 2019年第1期17卷 176-183页

作者： Robson C. Sousa Maria C. ferreira Haritz Altzibar Fábio B. Freire josé T. Freire Rural and Chemical Engineering Department Federal University of Espirito SantoAlegreES. Brazil Chemical Engineering Department Federal University of Sao CarlosSao CarlosSPBrazil Chemical Engineering Department University of Basque CountryBilbaoSpain

A contactor vessel was built to operate as either a mechanically or a conventional spouted bed for the purpose of analyzing the drying of pasty and granular materials under comparable conditions in both configurations. A classical conical–cylindrical spouted bed with a 60° conical base and an air inlet central orifice was modified to enable the switch by introducing in the vessel’s center an open helicoidal conveyor screw placed above the air inlet orifice. This screw is removable and conveniently returns the bed to its conventional spouted configuration. Experiments on drying solutions (calcium carbonate suspensions and skimmed milk) and granular materials (porous alumina particles) were performed for various bed parameter settings. The spouting pressure drop, outlet air temperature, and relative humidity were measured over time under different conditions. Mechanical agitation is proved effective in drying diluted carbonate calcium liquid suspensions and coarse porous alumina particles at an air velocity approximately 50% lower in comparison to drying in a conventional spouted bed. The conventional spouted bed performed better at drying liquid skimmed milk as the mechanical agitation combined with the axial inlet air flow is not effective in mitigating sticking and powder agglomeration in the bed when handling pastes of complex composition. Introducing mechanical agitation in the designed setup broadens the operating range of a conventional spouted bed with axial air flow in the inlet.

关键词： Characteristic curve Drying kinetic Spouted-bed dynamics Mechanical agitation Alumina particles Paste drying

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The changes on intimate partner violence against women in the health system in Portugal

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Health 2013年第7期5卷 65-70页

作者： Raquel cardoso josé Ornelas Instituto Superior de Psicologia Aplicada Instituto Universitário Lisbon Portugal Instituto Superior de Psicologia Aplicada Instituto Universitário Lisbon Portugal

In Portugal, over the last 20 years, we have seen great strides in addressing intimate partner violence against women by their male partners. Measuring and understanding progress, and achieving sustainable systems change is a major challenge and to achieve this aim we need to identify events, persons and settings that contribute for the critical factors that create long term transformations in the systems and the creation of new resources [1]. Since the healthcare system is one of the main actors of intervention with survivors, the goal of this project was to interview key stakeholders from the healthcare system in order to understand the main changes they perceive have happened over the past two decades. Based on interviews with key stakeholders, our study explores the evidences of the changes that occurred in the healthcare system, the intersections with other systems and their visions for the future.

关键词： Social Change Intimate Partner Violence against Women Health System

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Empty Soul Syndrome

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Journal of Behavioral and Brain Science 2018年第1期8卷 26-40页

作者： josé Humberto cardoso Resende Alfredo Nasser College (UNIFAN) Goiania Brazil

It is a syndrome with a set of signs and symptoms distinct from depression or panic syndrome, which is not characterized by the fear of dying, but by the desire to die in the form of suicide or in another quick way. Unlike depression or panic, it occurs more frequently between 60 and 80 years of age, according to the World Health Organization (WHO) report, which puts Brazil in eighth place among the countries with the highest incidence of suicides in the age range of 70 years. The report estimates a death every 40 seconds in the world, with India ranking first among the countries surveyed, according to the United Nations agency, in the WHO 2012 registries. It can occur in any person, regardless of color, religion, social class or schooling, being more common, however, among men, in the ratio of nine men to two women. It is very common among health practitioners or the self-employed. Causes are related to the general delusion involving body and mind, focusing on the lack of care. By the description of the dictionary, soul is the union of body and spirit, which some prefer to call mind. “Empty Soul” represents the lack of the very essence of life, a total void of wills, a finding of abandonment. For these symptoms or illness, the treatment has followed the line of “antidepressants” aimed at the reuptake of serotonin, such as SSRIs, MAOIs, anxiolytics (benzodiazepines) and painless techniques that reach the brain, used in neurology and psychiatry. We suggest, as a therapeutic idea, the realization of “Healing Workshops”, with the support being given in the form of meetings with motivational orientations, through positive stimuli, daily and constant psychotherapies, which the client will attend until cure is verified. This degree of disorder has presented in alarming proportions, especially after 2015. This work is justified by to the dramaticity of the deaths, such as: knife, shot, fall of great height, hunger strikes and forced isolation in prisons or kidnappings. In

关键词： Depression Panic Suicide Soul Disillusionment

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Widely tunable,high-power,femtosecond noncollinear optical parametric oscillator in the visible spectral range

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Photonics Research 2021年第9期9卷 1715-1718页

作者： ROBIN MEVERT YULIYA BINHAMMER CHRISTIAN M.DIETRICH LUISE BEICHERT joséR.cardoso DE ANDRADE THOMAS BINHAMMER JINTAO FAN UWE MORGNER Institute of Quantum Optics Leibniz University HannoverWelfengarten 1D-30167 HannoverGermany Cluster of Excellence PhoenixD Welfengarten 1D-30167 HannoverGermany neoLASE GmbH Hollerithallee 17D-30419 HannoverGermany

Ultrafast visible radiation is of great importance for many applications ranging from spectroscopy to *** some regions in the visible range are not covered by laser gain media,optical parametric oscillators offer an added *** a high-power broadband laser source,the ability to rapidly tune the frequency of pulses with high-power spectral density offers an extra benefit for experiments such as multicolor spectroscopy or ***,we demonstrate a broadband,high-power,rapidly tunable femtosecond noncollinear optical parametric oscillator with a signal tuning range of 440–720 nm in the visible *** oscillator is pumped by the third harmonic of an Yb-fiber laser at 345 nm with a repetition rate of 50.2 ***,the signal wavelength is tuned by changing the cavity length only,and output powers up to 452 m W and pulse durations down to 268 fs are *** is,to the best of our knowledge,the first demonstration of a quickly tunable femtosecond optical parametric oscillator that covers nearly the entire visible spectral range with high output power.

关键词： tunable power tuning

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