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西班牙华人移民的特性及社会文化对比

华夏文化论坛 2019年第1期 258-262页

作者：马康淑罗慧玲西班牙马德里康普顿斯大学东亚研究教研室

中国已经不再遥远,而是离我们越来越近:这个国内生产总值排名世界前列的经济体,自从加入了世界贸易组织(WTO)以后,产品在欧洲市场大受欢迎;2000年诺贝尔文学奖高行健、2012年的莫言都来自中国;中国来源女孩儿的国际收养成功案例屡见不鲜... 详细信息

中国已经不再遥远,而是离我们越来越近:这个国内生产总值排名世界前列的经济体,自从加入了世界贸易组织(WTO)以后,产品在欧洲市场大受欢迎;2000年诺贝尔文学奖高行健、2012年的莫言都来自中国;中国来源女孩儿的国际收养成功案例屡见不鲜;西班牙的街道上、学校里时常会见到中国人的身影;此外,2008年北京奥运会和2010年上海世博会的成功举办,也吸引了越来越多的西班牙企业家到中国投资……随着时代的发展,我们双方相互接近的愿望日渐强烈。本文旨在简单论述在新时期西班牙的华人移民现状~①。

关键词：西班牙华人移民社会融合文化差异

Adaptive optics as a tool for controlling the optical signals reaching the retina

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Annals of Eye Science 2017年第1期 331-333页

作者： joséJ.Esteve-Taboada Teresa Ferrer-Blasco Robert Montés-Micó Department of Optics and Optometry and Vision Sciences University of ValenciaValenciaSpain

The use of adaptive optics systems in ophthalmic research studies has increased in the last years thanks to the development of more accurate *** optics was first introduced in Astronomy for the correction of the effects produced by the turbulences of the Earth’s atmosphere when observing astronomical objects(1,2).Sophisticated deformable mirrors controlled by computers can correct in real time atmospheric disturbances,allowing for much finer details on the images of distance *** optics technology makes it possible to correct many of the aberrations with which the wavefront,i.e.,the geometric envelope of all the rays of light that emerged at the same time of the observed object,*** optics allows for obtaining sharper images,and thus,with better spatial resolution.

关键词： optics details correction

Preservation of platelet function in patients with cirrhosis and thrombocytopenia undergoing esophageal variceal ligation

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Hepatobiliary & Pancreatic Diseases International 2020年第6期19卷 555-560页

作者： Evandro de Oliveira Souza Elbio Antonio D’Amico Tania Rubia Flores da Rocha Caroline marcondes Ferreira Juliana Medeiros Batista Luiz Augusto CarneiroD’Albuquerque Flair jose Carrilho Alberto Queiroz Farias Division of Gastroenterology and Hepatology University of Sao Paulo School of MedicineAv.Dr.Eneas Carvalho de Aguiar2559th flooroffice 9159Sao PauloSP 05403-000Brazil Hemostasis Laboratory Hematology ServiceUniversity of Sao Paulo School of MedicineAv.Dr.Eneas Carvalho de Aguiar2552nd floorSao PauloSP 05403-000Brazil

Background:Thrombocytopenia is a possible risk factor for bleeding after band ligation of esophageal ***,elevated von Willebrand factor(VWF)in cirrhosis improves platelet function and could decrease this *** objective was to assess platelet function in patients with cirrhosis undergoing esophageal variceal ligation(EVL).Methods:The assessment consisted of platelet count,antigen and activity of VWF and VWF-cleaving protease ADAMTS-13 activity,and a platelet adhesion and aggregation test simulating vascular flow in vivo(Impact-RR)prior to ***:Totally 111 patients were divided into three groups according to platelet count:(1)100×109/L(n=26,23.4%).No statistically significant difference was found in the aggregate size of platelets[group 1:41.0(31.8–67.3)μm 2;group 2:47.0(33.8–71.3)μm 2;and group 3:47.0(34.0–66.0)μm 2;P=0.60]and no significant correlation was found between aggregate size and platelet count(Spearman r=0.07;P=0.47).Surface coverage was 4.1%(2.8%–6.7%),8.5%(4.0%–10.0%),and 9.0%(7.1%–12.0%)(P<0.001)in groups 1,2 and 3,respectively and correlated with platelet count(Spearman r=0.39;P<0.0001).There was no significant difference between groups in VWF or ***-EVL bleeding occurred in six(5.4%)patients(n=2 in group 1,n=1 in group 2,and n=3 in group 3;P=0.32).Patients with bleeding had higher MELD scores[15.0(11.3–20.3)versus 12.0(10.0–15.0);P=0.025],but no difference was demonstrated for platelet function ***:Platelet function is preserved even in the presence of thrombocytopenia,including in the patients with post-EVL bleeding.

关键词： Cirrhosis Hemostasis Thrombocytopenia Platelet aggregation Endoscopy Hemorrage

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秘鲁人面部形态特征的全基因组关联分析

基因组学与应用生物学 2021年第7期40卷 2810-2818页

作者：宋春波 Macarena Fuentes-Guajardo Kaustubh Adhikari 孙畅张曼菲李晴杨光睿 Rolando Gonzalez-josé Lavinia Schüler-Faccini Maria-Cátira Bortolini Victor Acuña-Alonzo Samuel Canizales-Quinteros Carla Gallo Giovanni Poletti Gabriel Bedoya Francisco Rothhammer Andrés Ruiz-Linares 复旦大学生命科学学院现代人类学教育部重点实验室上海200438

人类面部形态由神经外胚层发育而来,是区别个体的最显著特征之一。研究人面部特征的遗传机制可为生物医学、司法鉴定等应用领域提供依据。虽然目前已经在正常人群和患病人群中发现了一些与面部特征相关的基因,但是还有许多面部特征的基... 详细信息

人类面部形态由神经外胚层发育而来,是区别个体的最显著特征之一。研究人面部特征的遗传机制可为生物医学、司法鉴定等应用领域提供依据。虽然目前已经在正常人群和患病人群中发现了一些与面部特征相关的基因,但是还有许多面部特征的基因有待发现。本研究基于拉美人群进化和多样性研究联合会(consortium for the analysis of the diversity and evolution of Latin America,CANDELA)队列中的1140个秘鲁健康人群,通过标定其面部的47个特征点来计算中部和下部脸部面积,并计算47个特征点之间的欧式距离,以其结果作为表型;与约七十万个单核苷酸多态性(single nucleotide polymorphisms,SNPs)的全基因组分型数据进行全基因组关联分析(genome-wide association study,GWAS),并在CANDELA队列中的384个巴西和智利的独立健康人群中进行结果验证。本研究用一个加性遗传模型来进行线性回归关联检验,其中因变量为表型的数量性状,协变量为年龄、性别、身体质量指数(body mass index,BMI)及基因组群体分层分析中的前5个主成分(principal components,PCs)。研究结果表明,位于LD基因区(EDAR,LIMS1,RANBP2,SULT1C4,CCDC138,GCC2)的17个单核苷酸多态性与7个数量表型有很强的相关性;其中EDAR作为影响头面发育的一因多效性基因,在本研究中影响中部颅面形态。

关键词：面部形态特征全基因组关联分析加性遗传模型 EDAR LIMS1

Elastic Smart Contracts in Blockchains.

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自动化学报（英文版） 2021年第12期

作者： Schahram Dustda Pablo Fernández josé María García Antonio Ruiz-Cortés

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马南蒂亚莱斯大楼

建筑技艺 2010年第5期16卷 80-85页

作者： Luis Izquierdo W.,Antonia Lehmann S.B.,Raimundo Lira V.,josé Domingo Peafiel E. Miguel Villegas G.

马南蒂亚莱斯大楼位于圣地亚哥的一个始于20世纪50年代的花园社区规划的区域内，这个区域在过去的20年间经历了快速的城市化进程，社区内遍布着7～20层高的建筑，而且这里的土地价值也是目前圣地亚哥最高的，达到了2800USD／m2。该项目... 详细信息

马南蒂亚莱斯大楼位于圣地亚哥的一个始于20世纪50年代的花园社区规划的区域内，这个区域在过去的20年间经历了快速的城市化进程，社区内遍布着7～20层高的建筑，而且这里的土地价值也是目前圣地亚哥最高的，达到了2800USD／m2。该项目的客户是地产商，他们提出了以下几点要求：

关键词：大楼莱斯社区规划圣地亚哥城市化进程土地价值地产商花园

压力、含水量和温度对生活垃圾在模拟填埋过程中降解的影响

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环境卫生工程 2021年第1期29卷 96-96页

作者： Swanand Tupsakhare Tasnuva Moutushi marco J.Castaldi Morton A.Barlaz Scott Luettich Craig H.Benson 袁徐康(译) 施建勇(审查) 纽约市立大学化学工程系美国纽约100C1 北卡罗莱纳州立大学土木、建筑和环境工程学院美国 Geosyntec咨询公司美国缅因州奥古斯塔弗吉尼亚大学工学院美国弗吉尼亚州夏洛茨维尔河海大学

1研究亮点*在不同压力和温度条件下对模拟试样进行试验,在85℃时,CH_(4)/CO_(2)从1.0变为0.3,与现场监测结果吻合;*高压力比高温度对生成H2影响更大;城市固体废弃物中木材成分焦化速度比其他成分快;*CH_4/CO_(2)的变化趋势与高温填埋场... 详细信息

1研究亮点*在不同压力和温度条件下对模拟试样进行试验,在85℃时,CH_(4)/CO_(2)从1.0变为0.3,与现场监测结果吻合;*高压力比高温度对生成H2影响更大;城市固体废弃物中木材成分焦化速度比其他成分快;*CH_4/CO_(2)的变化趋势与高温填埋场非常吻合。

关键词：城市固体废弃物生活垃圾填埋场变化趋势现场监测结果 CH 含水量

Beneficial effects of saffron(Crocus sativus L.) in ocular pathologies, particularly neurodegenerative retinal diseases

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Neural Regeneration Research 2020年第8期15卷 1408-1416页

作者： jose A.Fernandez-Albarral Rosa de Hoz Ana I.Ramirez Ines Lopez-Cuenca Elena Salobrar-Garcia Maria D.Pinazo-Duran jose M.Ramirez Juan J.Salazar Instituto de Investigaciones Oftalmologicas Ramon Castroviejo MadridSpain Departamento de Inmunologia Oftalmologia y ORLFacultad de Optica y OptometriaMadridSpain Departamento de Inmunologia Oftalmologia y ORLFacultad de MedicinaMadridSpain Unidad de Investigacion Oftalmologica Santiago Grisolia Universidad de ValenciaValenciaSpain

Saffron(Crocus sativus L.)has been traditionally used in food preparation and as a medicinal *** currently has numerous therapeutic properties attributed to it,such as protection against ischemia,as well as anticonvulsant,antidepressant,anxiolytic,hypolipidemic,anti-atherogenic,anti-hypertensive,antidiabetic,and anti-cancer *** addition,saffron has remarkable beneficial properties,such as anti-apoptotic,anti-inflammatory and antioxidant activities,due to its main metabolites,among which crocin and crocetin stand ***,increasing evidence underwrites the possible neuroprotective role of the main bioactive saffron constituents in neurodegenerative diseases,such as Parkinson’s and Alzheimer’s diseases,both in experimental models and in clinical studies in ***,saffron supplementation is being tested for ocular neurodegenerative pathologies,such as diabetic retinopathy,retinitis pigmentosa,age-related macular degeneration and glaucoma,among others,and shows beneficial *** present article provides a comprehensive and up to date report of the investigations on the beneficial effects of saffron extracts on the main neurodegenerative ocular pathologies and other ocular *** review showed that saffron extracts could be considered promising therapeutic agents to help in the treatment of ocular neurodegenerative diseases.

关键词： AMD crocetin crocin Crocus sativus L. diabetic retinopathy glaucoma neuroprotection ocular diseases retinitis pigmentosa saffron safranal

MicroRNAs expression dynamics reveal post-transcriptional mechanisms regulating seed development in Phaseolus vulgaris L.

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Horticulture Research 2021年第1期8卷 195-211页

作者： jose Ricardo Parreira Michela Cappuccio Alma Balestrazzi Pedro Fevereiro Susana de Sousa Araujo Instituto de Tecnologia Quimica e Biologica Antonio Xavier Universidade Nova de LisboaAvenida da Republica2780-157 OeirasPortugal Department of Biology and Biotechnology“L.Spallanzani” University of Paviavia Ferrata 927100 PaviaItaly InnovPlantProtect Collaborative Laboratory Estrada de Gil Vaz7351-901 ElvasPortugal Present address:Association BLC3-Technology and Innovation Campus Centre Bio R&D UnitRua Nossa Senhora da Conceicao 2Lagares da Beira3405-155 Oliveira do HospitalPortugal

The knowledge on post-transcriptional regulation mechanisms implicated in seed development(SD)is still limited,particularly in one of the most consumed grain legumes,Phaseolus vulgaris *** explore for the first time the miRNA expression dynamics in *** developing ***-two known and 39 new miRNAs were found expressed in *** developing *** of the miRNAs identified were more abundant at 10 and 40 days after anthesis,suggesting that late embryogenesis/early filling and desiccation were SD stages in which miRNA action is more *** analysis and target prediction identified targets for 77 expressed *** several known miRNAs were predicted to target HD-ZIP,ARF,SPL,and NF-Y transcription factors families,most of the predicted targets for new miRNAs encode for functional ***-targets expression profiles evidenced that these miRNAs could tune distinct seed developmental *** more accumulated at early SD stages were implicated in regulating the end of embryogenesis,postponing the seed maturation program,storage compound synthesis and *** more accumulated at late SD stages could be implicated in seed quiescence,desiccation tolerance,and longevity with still uncovered roles in *** miRNAs herein described represent novel *** resources with potential application in future biotechnological approaches to modulate the expression of genes implicated in legume seed traits with impact in horticultural production systems.

关键词： mechanisms dynamics regulating