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Structural performance assessment of GFRP elastic gridshells by machine learning interpretability methods

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Frontiers of Structural and Civil Engineering 2022年第10期16卷 1249-1266页

作者： Soheila KOOKALANI Bin CHENG Jose Luis Chavez torres Department of Civil Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Civil Engineering Technical University of LojaLoja 110102Ecuador

The prediction of structural performance plays a significant role in damage assessment of glass fiber reinforcement polymer(GFRP)elastic gridshell *** learning(ML)approaches are implemented in this study,to predict maximum stress and displacement of GFRP elastic gridshell *** ML algorithms,including linear regression(LR),ridge regression(RR),support vector regression(SVR),K-nearest neighbors(KNN),decision tree(DT),random forest(RF),adaptive boosting(AdaBoost),extreme gradient boosting(XGBoost),category boosting(CatBoost),and light gradient boosting machine(LightGBM),are implemented in this *** features of structural performance considered in this study are the maximum stress as f1(x)and the maximum displacement to self-weight ratio as f2(x).A comparative study is conducted and the Catboost model presents the highest prediction ***,interpretable ML approaches,including shapely additive explanations(SHAP),partial dependence plot(PDP),and accumulated local effects(ALE),are applied to explain the *** is employed to describe the importance of each variable to structural performance both locally and *** results of sensitivity analysis(SA),feature importance of the CatBoost model and SHAP approach indicate the same parameters as the most significant variables for f1(x)and f2(x).

关键词： machine learning gridshell structure regression sensitivity analysis interpretability methods

Challenges in managing hepatitis C virus infection in cancer patients

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World Journal of Gastroenterology 2014年第11期20卷 2771-2776页

作者： Roy A Borchardt Harrys A torres Department of Infectious Diseases Infection Control and Employee HealthThe University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

Cancer patients have unique problems associated with hepatitis C virus(HCV)infection and treatment not seen in the general *** infection poses additional challenges and considerations for the management of cancer,and vice *** infection also can lead to the development of cancer,particularly hepatocellular carcinoma and non-Hodgkin *** severely immunocompromised cancer patients,diagnosis of HCV infection requires increased reliance on RNA detection *** infection can affect chemotherapy,and delay of HCV infection treatment until completion of chemotherapy and achievement of cancer remission may be required to decrease the potential for drug-drug interactions between antineoplastic agents and HCV therapeutics and potentiation of side effects of these *** addition,hematopoietic stem cell transplant(HSCT)recipients have an increased risk of early development of cirrhosis and *** this increased risk applies to all patients regardless of cancer treatment is ***,patients with cancer may have poorer sustained virological responses to HCV infection treatment than do those without ***,not all cancer patients are candidates for HCV infection *** this article,we review the challenges in managing HCV infection in cancer patients and HSCT recipients.

关键词： Hepatitis C virus Cancer Hematopoietic stem cell transplant Chemotherapy Treatment Antiviral Pegylated interferon Ribavirin

Renal elimination of organic anions in cholestasis

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World Journal of Gastroenterology 2008年第43期14卷 6616-6621页

作者： Adriana Mónica torres Facultad de Ciencias Bioquimicas y Farmacéuticas Universidad Nacional de RosarioCONICETSuipacha 5312000RosarioArgentina

The disposition of most drugs is highly dependent on specialized transporters. OAT1 and OAT3 are two organic anion transporters expressed in the basolateral membrane of renal proximal tubule cells, identified as contributors to xenobiotic and endogenous organic anion secretion. It is well known that cholestasis may cause renal damage. Impairment of kidney function produces modifications in the renal elimination of drugs. Recent studies have demonstrated that the renal abundance of OAT1 and OAT3 plays an important role in the renal elimination of organic anions in the presence of extrahepatic cholestasis. Time elapsed after obstructive cholestasis has an important impact on the regulation of both types of organic anion transporters. The renal expression of OAT1 and OAT3 should be taken into account in order to improve pharmacotherapeutic efficacy and to prevent drug toxicity during the onset of this hepatic disease.

关键词： Organic anions P-aminohippurate Furosemide OAT1 OAT3 Extrahepatic cholestasis

EULER SCHEME FOR FRACTIONAL DELAY STOCHASTIC DIFFERENTIAL EQUATIONS BY ROUGH PATHS TECHNIQUES

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Acta Mathematica Scientia 2019年第3期39卷 747-763页

作者： Johanna GARZON Samy TINDEL Soledad torres Departamento de Matematicas Universidad Nacional de ColombiaBogota D.C.Colombia Department of Mathematics Purdue University150 N.University StreetW.LafayetteIN 47907USA Facultad de Ingenierza CIMF AV Universidad de ValparaisoCasilla 123-V4059 ValparaisoChile

In this note, we study a discrete time approximation for the solution of a class of delayed stochastic differential equations driven by a fractional Brownian motion with Hurst parameter H ∈(1/2,1). In order to prove convergence, we use rough paths techniques. Theoretical bounds are established and numerical simulations are displayed.

关键词： Fractional Brownian motion stochastic differential equations rough paths,discrete time approximation

Use of two-surfactants mixtures to attain specific HLB values for assisted TPH-diesel biodegradation

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Journal of Environmental Sciences 2004年第6期16卷 950-956页

作者： Luis G. torres Neftalí Rojas Rosario Iturbe Instituto de Ingeniería Universidad Nacional Autó noma de México Coordinación de Ingeniería Ambiental Grupo Saneamiento de Suelos y Acuíferos Apartado Postal 70-472 Coyoacán 04510 México D.F. Mexico

In a surfactant assisted biodegradation process, the choice of surfactant(s) is of crucial importance. The question is: does the type of surfactant(i.e. chemical family) affect the biodegradation process at fixed hidrophillic-lypofillic balance(HLB) values? Microcosm assessments were developed using contaminated soil, with around of 5000 mg/kg of hydrocarbons as TPH-diesel. Mixtures of three nonionic surfactants were employed to get a wide range of specific HLB values. Tween20 and Span20 were mixed in the appropriate proportions to get HLB values between 8.6 and 16.7. Tween/Span60 mixtures reached HLB values between 4.7 and 14.9. Finally, Tween/Span80 combinations yielded HLB values between 4.3 and 15. TPH-diesel biodegradation was measured at the beginning, and after 8 weeks, as well as the FCU/gr soil, as a measure of microorganisms′ development during the biodegradation period. A second aim of this work was to assess the use of guar gum as a biodegradation enhancer instead of synthetic products. The conclusions of this work are that surfactant chemical family, and not only the HLB value clearly affects the assisted biodegradation rate. Surfactant's synergism was clearly observed. Regarding the use of guar gum, no biodegradation enhancement was observed for the three assessed concentrations, i.e., 2, 20, and 200 mg/kg, respectively. On the contrary, TPH-diesel removal was lower as the gum concentration increased. It is quite possible that guar gum was used as a microbial substrate.

关键词： aged soils enhanced bioremediation HLB mixtures Tween Span surfactants

Risk Transfer for Populations in Precarious Urban Environments

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International Journal of Disaster Risk Science 2020年第1期11卷 74-86页

作者： Juan Pablo Sarmiento Ana María torres-Munoz Extreme Events Institute/Disaster Risk and Resilience in the Americas(DRRA) Florida International UniversityMiamiFL 33199USA

This study explores risk transfer options that precarious and marginal urban communities could use to protect themselves from future damages and losses generated by socio-natural hazards and disasters at the individual and community levels. The design is framed within an evidence-based disaster risk reduction(DRR) strategy and follows the case study research approach. We analyze the2018 Neighborhood Approach for DRR programming evaluation carried out in four Latin American cities’ informal settlements and review relevant risk transfer experiences aimed at vulnerable populations. We calculate the pure risk premium for the four cases selected, using a previous catastrophe risk assessment for earthquakes and landslides. We propose three risk transfer options based on our analysis:(1) voluntary collective insurance;(2) structural reinforcement with a comprehensive housing insurance;and(3) hybrid parametric insurance. Risk transfer mechanisms conventionally focus on residual risk management. Here, due to the precariousness of the analyzed urban settings, the proposed alternatives go beyond the management of just residual risk to positively impact the beneficiaries’ quality of life and the reduction of the built environment’s physical vulnerability in the short and medium terms. Our study proposes a prospective estimation of future risk despite the limitations of data availability. This study opens a window to new approaches and proposes a systematic process to design DRR policy aimed at the poor and vulnerable strata of society.

关键词： Case study research Catastrophe risk assessment Informal settlements Risk transfer Urban precariousness Urban risk

Investigation of low grade thermal energy storage systems with phase changing materials

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能源与人工环境(英文) 2021年第4期2卷 366-373页

作者： Law torres Sevilla Jovana Radulovic School of Mechanical and Design Engineering Anglesea BuildingAnglesea RoadPortsmouth PO13DJUnited Kingdom

The use of phase changing materials(PCMs)for energy storage has been in the focus of scientific research for a while,primarily focusing on building cooling/heating applications due to favourable melting temperature *** this paper we simulated the suitability of encapsulated Paraffin Wax on a small scale in a low temperature thermal energy storage system using COMSOL *** absorption and heating dynamics were analysed for different inlet designs and velocities,and the thermal gradient was evaluated across the tank geometry in a number of charging *** show that paraffin wax proves to be a good storage medium based on its fast charging and good latent heat *** study found that although an addition of a second inlet to the system yields higher final temperatures and improves the heat transfer rate,it does so minimally and therefore is not notably *** designs follow the same heating dynamics independently on the final ***,higher or lower velocities benefit the system based on the design.

关键词： thermal energy phase

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布鲁斯博物馆美国格林威治

世界建筑导报 2024年第1期39卷 63-67页

作者： Noah Marble Vanessa Smith-torres Kyle Digby Sam Levison Mark Thorburn Max Katz Guan Wang Tim Hursley(摄影) Michael Biondo(摄影) EDR建筑事务所不详

布鲁斯博物馆是一家位于康涅狄格州格林威治的地区性文化机构,拥有多学科藏品和展览项目,将艺术、科学和自然历史融为一体。2014年,在一场全国性设计竞赛之后,布鲁斯博物馆踏上了振兴其园区的征程,以将该机构带入未来。竞赛结束后,设计... 详细信息

布鲁斯博物馆是一家位于康涅狄格州格林威治的地区性文化机构,拥有多学科藏品和展览项目,将艺术、科学和自然历史融为一体。2014年,在一场全国性设计竞赛之后,布鲁斯博物馆踏上了振兴其园区的征程,以将该机构带入未来。竞赛结束后,设计团队领导了一项严格的初步规划研究,深入挖掘博物馆的需求,并为其作为社区资源的能力提供支持。

关键词：布鲁斯设计竞赛康涅狄格州社区资源博物馆展览项目初步规划格林威治

Lights for epilepsy:can photobiomodulation reduce seizures and offer neuroprotection?

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Neural Regeneration Research 2023年第7期18卷 1423-1426页

作者： Napoleon torres-Martinez Stephan Chabardes John Mitrofanis University of Grenoble Alpes FDD and CEA-LETIClinatecGrenobleFrance

Epilepsy is synonymous with individuals suffering repeated“fits”or *** seizures are triggered by bursts of abnormal neuronal activity,across either the cerebral cortex and/or the *** addition,the seizure sites are characterized by considerable neuronal *** the factors that generate this abnormal activity and death are not entirely clear,recent evidence indicates that mitochondrial dysfunction plays a central *** treatment options include drug therapy,which aims to suppress the abnormal neuronal activity,or surgical intervention,which involves the removal of the brain region generating the seizure ***,~30%of patients are unresponsive to the drugs,while the surgery option is invasive and has a morbidity ***,there is a need for the development of an effective non-pharmacological and non-invasive treatment for this disorder,one that has few side *** this review,we consider the effectiveness of a potential new treatment for epilepsy,known as photobiomodulation,the use of red to near-infrared light on body *** studies in animal models have shown that photobiomodulation reduces seizure-like activity and improves neuronal ***,it has an excellent safety record,with little or no evidence of side effects,and it is *** all together,this treatment appears to be an ideal treatment option for patients suffering from epilepsy,which is certainly worthy of further consideration.

关键词： cell death gliosis inflammation infrared mitochondria non-pharmacological red seizure