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Blockage of the habenular nucleus can eliminate dyspnea induced by electrostimulation of the insular cortex

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Neural Regeneration Research 2010年第13期5卷 1025-1029页

作者： Mingxian Li jinghua wang Min Huang Weihong Lin Min wang Lei Yu Shao wang Department of Respiratory Medicine First Hospital Jilin University Changchun 130021 Jilin Province China Department of Physiology Bethune School of Medicine Jilin University Changchun 130021 Jilin Province China Department of Neurology First Hospital Jilin University Changchun 130021 Jifin Province China

BACKGROUND： The insular cortex and habenular nucleus may be a regulatory center for obstructive sleep apnea syndrome, and dyspnea may be caused by insular cortex activity. The insular cortex is a cortical representation of obstructive sleep apnea syndrome. The habenular nucleus is a station for descending insular cortex activity. OBJECTIVE： Through actively stimulating the rat insular cortex, to observe rat respiratory movement, myoelectric activities of genioglossus, arterial partial pressure of oxygen, partial pressure of carbon dioxide and acidity-alkalinity, and to verify a hypothesis that the insular cortex is a superior-position regulation center, and the habenular nucleus is an inferior-position nervous nuclei of the insular cortex in patients with obstructive sleep apnea syndrome. DESIGN, TIME AND SETTING： The randomized, controlled animal study was performed at the Laboratory of Electrophysiology, Department of Physiology, Norman Bathune College of Medicine, Jilin University, China from September 2004 to June 2008. MATERIALS： We used L-glutamic acid （Dingguo Biological Product Research Center, Beijing, China）, lidocaine hydrochloride （Seventh Pharmacy Co., Ltd., Wuxi, China）, electric stimulator （Nihon Kohden, Japan）, and an AVL-OPTI blood gas analyzer （AVL Scientific Co., Roswell, GA, USA）. METHODS： The insular cortex of healthy adult Wistar rats underwent electrostimulation and L-glutamic acid stimulation to record changes in the myoelectric activity of genioglossus and respiratory movement. Some rats were injected with lidocaine to block the habenular nucleus before electrostimulation or L-glutamic acid stimulation. L-glutamic acid and lidocaine were injected by microelectrodes embedded in nuclear groups. MAIN OUTCOME MEASURES： Myoelectric activities of genioglossus, arterial partial pressure of oxygen, partial pressure of carbon dioxide and acidity-alkalinity were measured following apnea in rats undergoing electrostimulation in the insular cortex and f

关键词： dyspnea habenular nucleus insular cortex genioglossus neuroelectrophysiology neural regeneration

LARGE TIME STEP GENERALIZATION OF RANDOM CHOICE FINITE DIFFERENCE SCHEME FOR HYPERBOLIC CONSERVATION LAWS

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Acta Mathematica Scientia 1989年第1期9卷 33-42页

作者： wang jinghua Inst. of Syst. Sci., Academia Sinica, Beijing, China Inst. of Syst. Sci. Academia Sinica Beijing China

A natural generalization of random choice finite difference scheme of Harten and Lax for Courant number larger than 1 is obtained. We handle interactions between neighboring Riemann solvers by linear superposition of their conserved quantities. We show consistency of the scheme for arbitrarily large Courant numbers. For scalar problems the scheme is total variation diminishing.A brief discussion is given for entropy condition.

关键词： LARGE TIME STEP GENERALIZATION OF RANDOM CHOICE FINITE DIFFERENCE SCHEME FOR HYPERBOLIC CONSERVATION LAWS STEP

Pre-harvest and post-harvest application of benzothiadiazole for controlling anthracnose and extending shelf life of harvested banana

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International Journal of Agricultural and Biological Engineering 2013年第4期6卷 76-83页

作者： Li Xueping Shi Jingying Zhu Xiaoyang wang jinghua Yuan Zhenxin Luo Jun Liu Tongxin wang Rong Rao Shen Chen Weixin State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources/Guangdong Provincial Key Laboratory for Postharvest Science and Technology of Fruits and Vegetables College of HorticultureSouth China Agricultural UniversityGuangzhou 510642China College of Food Science and Engineering Shandong Agricultural UniversityTaian 271018China

Anthracnose,caused by the fungus Colletotrichum musae,is a serious latent post-harvest disease of banana,which results in major economic losses during transportation and ***-thiadiazole-7-carbothioic acid S-methyl ester(BTH),a functional analogue of the plant endogenous hormone-like compound salicylic acid(SA),has been known to possess resistant effects on some diseases caused by *** aim of present study was to select an appropriate BTH concentration and an appropriate stage of banana ripening for its application in controlling anthracnose and extending shelf life of harvested banana *** concentrations of BTH(50,100,200 and 300μg/mL)were applied at different stages of banana fruit ripening,including one week,two weeks and one month before *** results suggest that while the concentrations of BTH ranging from 50μg/mL to 200μg/mL in both pre-harvest and post-harvest application,this could control anthracnose of harvested banana fruit,the appropriate concentration of BTH in both pre-harvest and post-harvest treatment was 100μg/mL and the best time of BTH treatment was two weeks before *** of quality parameters including peel color and firmness indicated that 100μg/mL BTH treatment delayed banana fruit ripening at room temperature.

关键词： banana fruit shelf life ripening post-harvest preservation BTH treatment anthracnose peel color firmness

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客户稳定性与企业成本粘性

审计与经济研究 2023年第6期38卷 55-64页

作者：王菁华毕超南京审计大学会计学院江苏南京211815 南京审计大学智能管理会计与内部控制研究院江苏南京211815

以供应商-客户关系为切入点,研究客户稳定性对企业成本粘性的影响,发现客户稳定性可以显著提升上游供应商企业的成本粘性,这一结论在采用Heckman两阶段检验、倾向得分匹配、双重差分法以及控制其他潜在影响因素等进行稳健性检验之后仍... 详细信息

以供应商-客户关系为切入点,研究客户稳定性对企业成本粘性的影响,发现客户稳定性可以显著提升上游供应商企业的成本粘性,这一结论在采用Heckman两阶段检验、倾向得分匹配、双重差分法以及控制其他潜在影响因素等进行稳健性检验之后仍然成立。机制研究发现,稳定客户通过改变上游企业的调整成本、提高管理层乐观预期而最终影响企业成本粘性。异质性分析结果表明,当地区社会信任程度更高、客户关系更好、经济政策不确定性更大时,稳定客户带来的成本粘性提升效应更为明显。经济后果检验发现,客户稳定性导致的成本粘性对未来企业销售利润率具有积极的促进作用,是供应商企业储备资源、为未来蓄力的重要表征,反映了供应商企业的战略性成本决策行为。

关键词：客户稳定性企业成本粘性调整成本管理层预期产业链供应链代理成本

诉讼风险如何影响企业费用粘性?——来自中国上市公司的证据

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会计研究 2022年第12期 119-137页

作者：王菁华毕超南京审计大学会计学院 211815 南京审计大学智能管理会计与内部控制研究院 211815

诉讼是干扰企业正常运营的重要事件,不仅会导致声誉危机和潜在损失、还会增加执行成本,进而影响到企业的成本决策。本文考察了诉讼风险对企业费用粘性的影响效应,并对其中介机制进行了分析。研究发现,诉讼风险会显著降低企业费用粘性,... 详细信息

诉讼是干扰企业正常运营的重要事件,不仅会导致声誉危机和潜在损失、还会增加执行成本,进而影响到企业的成本决策。本文考察了诉讼风险对企业费用粘性的影响效应,并对其中介机制进行了分析。研究发现,诉讼风险会显著降低企业费用粘性,且诉讼风险主要是通过影响调整成本、增加管理层悲观预期而作用于企业费用粘性。此外,针对诉讼案件类型、企业特质与宏观法律环境的异质性检验表明,诉讼风险与企业费用粘性的负相关关系仅在资金类诉讼案件中存在,而在产品类诉讼样本中,诉讼风险反而会提高企业费用粘性;当企业上年销售收入下滑、财务柔性水平较低以及规模较小时,诉讼风险带来的费用粘性降低效应更为明显;诉讼风险对于企业费用粘性的负向影响主要存在于地区法制化水平较低的样本中。本文从成本性态视角阐述了诉讼风险影响企业成本决策的行为逻辑,丰富和拓展了“法律与企业行为”的研究成果,同时也为企业更好地应对法律纠纷和开展成本管理活动提供了有益参考。

关键词：诉讼风险费用粘性调整成本管理层预期

Role of 5-hydroxytryptamine expression in cerebellar Purkinje cells in obstructive sleep apnea syndrome

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Neural Regeneration Research 2012年第8期7卷 606-610页

作者： Liping Peng jinghua wang Lihong Zhang Pan Liu Min wang Min Huang Shengnan Liu Pingping He Li Cui Mingxian Li Shao wang Department of Pneumology First Affiliated Hospital of Jilin University Changchun 130021 Jilin Province China Key Laboratory of Pathobiology Ministry of Education Jilin University Changchun 130021 Jilin Province China Department of Physiology Norman Bethune College of Medicine Jilin University Changchun 130021 Jilin Province China Department of Neurology First Affiliated Hospital of Jilin University Changchun 130021 Jilin Province China

In the present study, electrical stimulation to the rat insular cortex induced apnea or respiratory disturbance, reduced amplitude of genioglossal electromyogram, and decreased electromyogram integrals. In addition, arterial blood gas analysis showed arterial blood acidosis, reduced pH values, increased alkali reserve negative values, decreased peripheral blood 5-hydroxytryptamine content, and increased 5-hydroxytryptamine expression in cerebellar Purkinje cells. Following lidocaine injection to block the habenular nucleus, abnormalities in breath, genioglossal electromyogram, and blood gas values disappeared, and peripheral blood 5-hydroxytryptamine content returned to levels prior to electric stimulation. However, 5-hydroxytryptamine expression in cerebellar Purkinje cells remained high. The results suggested that 5-hydroxytryptamine expression in Purkinje cells did not correlate with ventilation function involving insular cortex and habenular nucleus.

关键词： sleep apnea obstructive cerebellum 5-hydroxytryptamine insular cortex habenular nucleus Purkinje cells

Transformation and Development of Financial Institutions under Stringent Regulations

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China Economic Transition 2020年第2期3卷 119-131页

作者： wang jinghua HAO Zhiyun of the Internal Audit Bureau Head Office of the Industrial and Commercial Bank of China(ICBC) the Internal Audit Bureau Head Office of the ICBC of China Institute for Reform and Development

After the growth phase featured by high-leverage,expansion of shadow banks,and increased potential risks,the financial industry in China now enters the phase of stringent regulation and *** December 7,2018,the China Banking and Insurance Regulation Commission(CBIRC)disclosed 10 penalties to the tune of RMB156.3 million in fines and *** the Central Economic Work Conference held at the end of 2018,a new requirement was proposed to strengthen financial regulation and to win the battle on preventing and defusing *** the beginning of 2019,President Xi Jinping also made a key deployment on deepening financial reform on the supply side,calling for the optimization of financial services,and preventing financial ***,the phase of financial expansion characterized by financial liberalization,shadow banking,and the rapid growth of Internet finance is coming to a turning *** the phase of stringent regulation,the financial sector should respond actively,make early preparations and clarify the boundary for profit growth and compliance development,break away from the current situation that lacking both high-quality assets and stable low-cost liabilities,and balance business innovation and prudential risk control to ensure the momentum of sustainable and sound growth.

关键词： finance Institution Transformation

在线教学模式下高校英语教师评价素养发展与影响因素研究——以京津冀地区为例

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河北大学学报（哲学社会科学版） 2023年第3期48卷 69-79页

作者：王亚南王京华华北电力大学英语系河北保定071003 河北大学公共外语教学部河北保定071002

提升教师评价素养是保障教学质量的关键。通过对京津冀地区259名高校英语教师进行问卷调查和访谈,考察在线教学模式下高校英语教师评价素养现状。研究发现,教师评价素养处于中等偏上水平,其中评价知识相对扎实,评价态度有待提高。教龄... 详细信息

提升教师评价素养是保障教学质量的关键。通过对京津冀地区259名高校英语教师进行问卷调查和访谈,考察在线教学模式下高校英语教师评价素养现状。研究发现,教师评价素养处于中等偏上水平,其中评价知识相对扎实,评价态度有待提高。教龄和教育专业背景对教师评价素养具有显著影响。此外,教师评价素养受到评价意愿、政策、自主学习等因素的显著影响。最后指出提升教师评价自主性、构建教师学习共同体、完善教师评价机制是提高教师评价素养的有效方式。

关键词：高校英语教师评价素养在线教学影响因素

THE RISK ASSESSMENT OF THE LONG-DISTANCE OILPIPELINE ENGINEERING

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Journal of Geographical Sciences 1996年第1期6卷 78-83页

作者： wang jinghua Mu Congru(Institute of Geography, CAS, Beijing 100101People’s Republic of China) Institute of Geography CAS Beijing 100101 China

The oilfield construction and long-distance oil pipeline engineering has been developed extensively in China. The risk assessment of oil industry will, however, be an important objective to cope with the development of oil industry , The risk assessment of oil industry has many subjects worthy to be *** major purpose of the paper is to research the risk cases of long-distance oil pipeline engineering in Ganshu and Shaanxi provinces.

关键词： long-distance oil pipeline risk assessment engineering Gansu Shaanxi