检索结果-南通市图书馆

BiCuSeO as state-of-the-art thermoelectric materials for energy conversion:from thin films to bulks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2018年第4期37卷 259-273页

作者： Rui Liu Xing Tan Yao-Chun Liu Guang-Kun Ren jin-le lan Zhi-Fang Zhou Ce-Wen Nan Yuan-Hua Lin State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical Technology

BiCuSeO-based thermoelectric material has attracted great attention as state-of-the-art thermoelectric materials since it was first reported in 2010. In this review, we update the studies on the BiCuSeO thin films first. Then, we focus on the most recent progress of multiple approaches that enhance the thermoelectric performance including advanced synthesized technologies, notable mechanisms for higher power factor （optimizing carrier concentration, carrier mobility, Seebeck coefficient） and doping effects predicted by calculation. And finally, aiming at further enhancing the performance of these materials and ultimately commercial application, we give a brief discussion on the urgent issues to which should be paid close attention.

关键词： BiCuSeO State-of-the-art thermoelectricmaterials Thin films Bulks

Therapeutic strategies of targeting nonapoptotic regulated cell death (RCD) with smallmolecule compounds in cancer

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第7期14卷 2815-2853页

作者： Xin jin Wenke jin Linlin Tong Jia Zhao lan Zhang Na Lin Department of Ultrasound Department of Medical Oncology and Department of Hematologythe First Hospital of China Medical UniversityChina Medical UniversityShenyang 110001China Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs School of Life Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China

Regulated cell death(RCD)is a controlled form of cell death orchestrated by one or more cascading signaling pathways,making it amenable to pharmacological *** subroutines can be categorized as apoptotic or non-apoptotic and play essential roles in maintaining homeostasis,facilitating development,and modulating *** evidence has recently revealed that RCD evasion is frequently the primary cause of tumor *** non-apoptotic RCD subroutines have garnered attention as promising cancer therapies due to their ability to induce tumor regression and prevent relapse,comparable to ***,they offer potential solutions for overcoming the acquired resistance of tumors toward apoptotic *** an increasing understanding of the underlying mechanisms governing these non-apoptotic RCD subroutines,a growing number of small-molecule compounds targeting single or multiple pathways have been discovered,providing novel strategies for current cancer *** this review,we comprehensively summarized the current regulatory mechanisms of the emerging non-apoptotic RCD subroutines,mainly including autophagy-dependent cell death,ferroptosis,cuproptosis,disulfidptosis,necroptosis,pyroptosis,alkaliptosis,oxeiptosis,parthanatos,mitochondrial permeability transition(MPT)-driven necrosis,entotic cell death,NETotic cell death,lysosome-dependent cell death,and immunogenic cell death(ICD).Furthermore,we focused on discussing the pharmacological regulatory mechanisms of related small-molecule *** brief,these insightful findings may provide valuable guidance for investigating individual or collaborative targeting approaches towards different RCD subroutines,ultimately driving the discovery of novel small-molecule compounds that target RCD and significantly enhance future cancer therapeutics.

关键词： Regulated cell death(RCD) Non-apoptotic RCD subroutine Autophagy Ferroptosis Necroptosis Regulatory mechanism Small-molecule compound Cancer therapy

Mechanisms of inclusion-induced pitting of stainless steels:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2024年第1期168卷 143-156页

作者： Yangting Sun Xin Tan Rulei lan Guoyong Ran jin Li Yiming Jiang Department of Materials Science State Key Laboratory of Molecular Engineering of PolymersFudan UniversityShanghai 200438China

Pitting is a common type of localized corrosion in passive alloys that can cause rapid failure of material or *** the case of stainless steels,non-metallic inclusions have been identified as the most susceptible sites for pitting,and have therefore garnered significant *** review critically ex-amines the issue of how inclusions induce pitting,with a particular focus on three mechanisms:sponta-neous dissolution of inclusions,active dissolution of Cr-depleted regions,and propagation of microcracks at the inclusion-matrix *** researchers have made significant strides in understanding these mechanisms over the past few decades,many gaps and controversies *** such as the ini-tial driving force of inclusion dissolution and factors affecting Cr-depleted regions require further ***,some old concepts and methods need to be revised to arrive at more credible *** review aims to delve deeply into these important issues and provide inspiration for future research.

关键词： Pitting Inclusion Stainless steel Localized corrosion MnS

Ethnographic Research on the Formation Path of Preschool Children’s Peer Cultures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Education in China 2024年第2期19卷 174-203页

作者： LIN lan jin Xiangjun College of Teacher Education Ningbo UniversityNingbo 315211China

As a major branch of children’s studies and a clear manifestation of adherence to a child-oriented position,research on children’s peer cultures is of significant value for understanding the true world of *** an ethnographic approach,this study conducts in-depth field observations in three kindergartens to explore how preschool children create their peer *** results indicate that the children in three kindergartens created a series of meaningful symbols within their respective kindergarten settings during peer interaction and formed their peer *** study finds that:Firstly,children’s peer cultures encompass five core themes,namely,self-presentation,friendly interaction,conflict and segregation,collective play routines,and secondary adjustments to classroom ***,the development of children’s selves,shared play among children,interpretive reconstruction of adult cultures,and inclusiveness of school cultures are inherent sources of strength,core driving force,mechanisms for the path,and external environmental factors of the formation of children’s peer ***,children gain membership in the cultures to which they belong through collective participation in social ***,children produce peer cultures and contribute to the renewal of adult cultures by creatively appropriating information and knowledge from the adult *** this connection,it is essential for kindergartens to support the development of children’s peer cultures.

关键词： children’s peer cultures ethnography children’s studies

The inhomogeneous incompressible Hall-MHD system with only bounded density

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Mathematics 2024年

作者： jin Tan lan Zhang Laboratoire de Math′ematiques AGM UMR CNRS 8088 Cergy Paris Universit′e Center for Mathematical Sciences and Department of Mathematics Wuhan University of Technology

This paper is dedicated to the global-in-time existence and uniqueness issues of solutions for the inhomogeneous incompressible Hall-magnetohydrodynamics(MHD) system with merely bounded density. In a three-dimensional case, assuming that the initial density is a small perturbation of a positive constant in the L∞norm, we prove global well-posedness for small initial velocity and magnetic fields in critical Besov spaces. Next, we consider the so-called 21/2D flows for the inhomogeneous Hall-MHD system(that is 3D flows independent of the vertical variable) and establish the global existence of strong solutions by only assuming that the initial magnetic field is small in critical spaces and the initial density is bounded and bounded away from zero. In particular, those solutions allow piecewise constant density with jumps so that a mixture of fluids can be considered. Compared with inhomogeneous incompressible Navier-Stokes equations, the new difficulties of proving these results come from the additional so-called Hall term, which endows the magnetic equation with a quasi-linear character. In order to overcome them, we reformulate the system by taking advantage of the curl form of the magnetic equation and develop some new maximal regularity estimates for the Stokes system with just bounded coefficients.

关键词：

Molecularly imprinted sensor based on carboxylated carbon nanotubes/Keggin-type polyoxometalates nanocomposite for the detection of furazolidone

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Tungsten 2024年第2期6卷 394-409页

作者： Yu-lan Huang Bing Zhang Yu-Lian Li Li Wang le Dong Jian Li College of Ocean Food and Biological Engineering Jimei UniversityXiamen 361021China College of Oceanology and Food Science Quanzhou Normal UniversityQuanzhou 362000China

Due to its properties of mutagenic,teratogenic,and carcinogenic,the detection of furazolidone(FZD)in aquaculture is of great importance for food safety and human *** this study,molecularly imprinted fi lms modifi ed with carboxylated multi-walled carbon nanotube-phosphomolybdic acid composite were used to fabricate an electrochemical sensor for the determination of *** nanocomposites were characterized using infrared spectroscopy,scanning electron microscopy,energy-dispersive X-ray spectroscopy,and X-ray diff *** electrochemical characteristics of the modifi ed electrodes were examined using electrochemical impedance spectroscopy,cyclic voltammetry,and diff erential pulse *** sensor exhibited exceptional catalytic *** calibration curves were acquired in the concentration range of 6 nmol·L^(−1)to 0.6μmol·L^(−1),with a limit of detection of 3.38 nmol·L^(−1).Additionally,the sensor proved successful in recognizing FZD in shrimp samples with satisfactory recoveries and *** method provides a strategy to construct a molecularly imprinted electrochemical sensing platform using nanomaterials,which has great promise in the field of food safety.

关键词： Phosphomolybdate Furazolidone Polyoxometalates Carboxylated multi-walled carbon nanotube Molecularly imprinted polymers Electrochemical sensor

Effect of multiple coulomb scattering on the beam tests of silicon pixel detectors

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第4期35卷 200-207页

作者： lan-Kun Li Ming-Yi Dong Ze Gao Liang-Cheng-Long jin Shu-Jun Zhao School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Particle Detection and Electronics(Institute of High Energy Physics CAS)Beijing 100049China University of Chinese Academy of Science Beijing 100049China University of South China Hengyang 421001China

In the research and development of new silicon pixel detectors,a collimated monoenergetic charged-particle test beam equipped with a high-resolution pixel-beam telescope is crucial for prototype verification and performance *** the beam energy is low,the effect of multiple Coulomb scattering on the measured resolution of the Device Under Test(DUT)must be considered to accurately evaluate the performance of the pixel chips and *** study aimed to investigate the effect of multiple Coulomb scattering on the measured resolution,particularly at low beam *** were conducted using Allpix^(2) to study the effects of multiple Coulomb scattering under different beam energies,material budgets,and telescope *** simulations also provided the minimum energy at which the effect of multiple Coulomb scattering could be *** with the results of a five-layer detector system tested with an electron beam at DESY,the simulation results were consistent with the beam test results,confirming the reliability of the simulations.

关键词： Silicon Pixel Detectors Beam Telescope Multiple Coulomb Scattering Spatial Resolution

Free-moving-state microscopic imaging of cerebral oxygenation and hemodynamics with a photoacoustic fiberscope

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第1期13卷 33-46页

作者： Xiaoxuan Zhong Yizhi Liang Xiaoyu Wang Haoying lan Xue Bai Long jin Bai-Ou Guan Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications Institute of Photonics TechnologyJinan UniversityGuangzhou510632China

We report the development of a head-mounted photoacoustic fiberscope for cerebral imaging in a freely behaving *** 4.5-gram imaging probe has a 9-µm lateral resolution and 0.2-Hz frame rate over a 1.2-mm wide *** probe can continuously monitor cerebral oxygenation and hemodynamic responses at single-vessel resolution,showing significantly different cerebrovascular responses to external stimuli under anesthesia and in the freely moving *** example,when subjected to high-concentration CO_(2) respiration,enhanced oxygenation to compensate for hypercapnia can be visualized due to cerebral regulation in the freely moving *** studies exhibit significantly weakened compensation capabilities in obese *** new imaging modality can be used for investigating both normal and pathological cerebrovascular functions and shows great promise for studying cerebral activity,disorders and their treatments.

关键词： cerebral anesthesia moving

A novel insight of enhancing the hydrogen peroxide tolerance of unspecific peroxygenase from Daldinia caldariorum based on structure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical letters 2024年第4期35卷 426-430页

作者： Tiantian Li Ruochen jin Bin Wu Dongming lan Yunjian Ma Yonghua Wang School of Food Science and Engineering South China University of TechnologyGuangzhou 510640China School of Bioscience and Bioengineering South China University of TechnologyGuangzhou 510006China Guangdong Youmei Institute of Intelligent Bio-manufacturing Co. Ltd.Foshan 528200China

Unspecific peroxygenases(UPOs, EC 1.***.2.1) is a kind of thioheme enzyme capable of catalyzing various oxidations of inert C–H bonds using H_(2)O_(2) as an oxygen donor without cofactors. However, the enhancement of the H_(2)O_(2) tolerance of UPOs is always challenging. In this study, the A161C mutant of r Dca UPO,which originates from Daldinia caldariorum, was found to be highly H_(2)O_(2)-resistant. Compared with the wild type, the mutant r Dca UPO-A161C showed a 10-h prolonged half-life and a 64% improved enzyme activity when incubated in 10 mmol/L H_(2)O_(2). The crystal structure analysis at 1.47 A showed that r Dca UPOA161C exhibited 10 α-helixes(cyan) and a series of ordered rings, forming a single asymmetric spherical structure. The two conserved domains near heme formed an active site with the catalytic PCP and EHD regions(Glu86, His87, Asp88 residues). The H_(2)O_(2) tolerance of r Dca UPO-A161C was preliminarily explored by comparing its structure with the wild type. Notably, r Dca UPO-A161C showed significantly higher catalytic efficiency than the wild type for the production of hydroxyl fatty acids. This study is anticipated to provide an insight into the structure-function relationship and expand potential applications of UPOs.

关键词： Unspecific peroxygenase Molecular modification Hydrogen peroxide stability Crystal structure Hydroxyl fatty acids