检索结果-南通市图书馆

Genesis, metallogenic model, and prospecting prediction of the Nibao gold deposit in the Guizhou Province, China

在线全文

学校读者我要写书评

暂无评论

Acta Geochimica 2023年第1期42卷 136-152页

作者： Weifang Song Lulin Zheng jianzhong Liu Shengtao Cao Zhuojun Xie College of Resource and Environmental Engineering Guizhou UniversityGuiyang 550025China College of Mining Guizhou UniversityGuiyang 550025China Six Geological Team of Hubei Geological Bureau Xiaogan 432000China Guizhou Bureau of Geology and Mineral Exploration&Development Guiyang 550004China Innovation Center Ore Resources Exploration Technology in the Region of Bedrock Ministry of Natural Resources of People’s Republic of ChinaGuiyang 550018China Key Laboratory of Ore Deposit Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550025China

Southwestern Guizhou province is one of China’s most important distribution areas of Carlin-type gold deposits. The Nibao deposit is a typical gold deposit in southwestern Guizhou. To elucidate the genesis of the Nibao gold deposit, establish a metallogenic model, and guide prospecting prediction, we systematically collected previously reported geological, geochemical, and dating data and discussed the genesis of the Nibao gold deposit,based on which we proposed the metallogenic *** works show that the Nibao anticline, F1 fault, and its hanging wall dragged anticline(Erlongqiangbao anticline) were formed before or simultaneously with gold mineralization, while F2, F3, and F4 faults postdate gold mineralization. Regional geophysical data showed extensive low resistivity anomaly areas near the SBT(the product of tectonic slippage and hydrothermal alteration)between the P2/P3 and the strata of the Longtan Formation in the SSE direction of Nibao anticline in the lower plate of F1 and hanging wall dragged anticline(Erlongqiangbao anticline), and the anomaly areas are distributed within the influence range of anticlines. Simultaneously, soil and structural geochemistry show that F1, Nibao anticline,Erlongqiangbao anticline, and their transition areas all show good metallogenic elements(Au, As, and S) assemblage anomalies, with good metallogenic space and prospecting possibilities. There are five main hypotheses about the source of ore-forming fluids and Au in the Nibao gold deposit:(1) related to the Emeishan mantle plume activity;(2) source from the Emeishan basalt;(3) metamorphic fluid mineralization;(4) basin fluid mineralization;(5) related to deep concealed magmatic rocks;of these, the mainstream understanding is the fifth speculation. It is acknowledged that the ore-forming fluids are hydrothermal fluids with medium–low temperature, high pressure, medium–low salinity, low density, low oxygen fugacity, weak acidity, weak reduction, and rich in CO_(2)and CH_

关键词： Nibao gold deposit Source of ore-forming fluids and Au Genesis Metallogenic model Prospecting prediction

Development of 3D bioprinting:From printing methods to biomedical applications

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2020年第5期15卷 529-557页

作者： Zeming Gu jianzhong Fu Hui Lin Yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province School of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310058China

Biomanufacturing of tissues/organs in vitro is our big dream,driven by two needs:organ transplantation and accurate tissue *** the last decades,3D bioprinting has been widely applied in the construction of many tissues/organs such as skins,vessels,hearts,etc.,which can not only lay a foundation for the grand goal of organ replacement,but also be served as in vitro models committed to pharmacokinetics,drug screening and so *** organs are so complicated,many bioprinting methods are exploited to figure out the challenges of different *** the question is how to choose the suitable bioprinting method?Herein,we systematically review the evolution,process and classification of 3D bioprinting with an emphasis on the fundamental printing principles and commercialized *** summarize and classify extrusion-based,dropletbased,and photocuring-based bioprinting methods and give some advices for *** them,coaxial and multi-material bioprinting are highlighted and basic principles of designing bioinks are also discussed.

关键词： 3D bioprinting Extrusion-based bioprinting Droplet-based bioprinting Photocuring-based bioprinting Bioink

using statolith shape analysis to identify fi ve commercial Loliginidae squid species in Chinese waters

在线全文

学校读者我要写书评

暂无评论

Journal of Oceanology and Limnology 2021年第3期39卷 1160-1167页

作者： jianzhong GuO Dan LIu Chi ZHANG Yongjun TIAN Zhixin LI Fisheries College Ocean University of ChinaQingdao 266003China Frontiers Science Center for Deep Ocean Multispheres and Earth System(FDOMES) Ocean University of ChinaQingdao 266100China Laboratory for Marine Fisheries Science and Food Production Processes Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China

Identification of squids in the family Loliginidae is a time-consuming exercise because of the highly overlapping distributions of species and their overall similarity(fin shape and size,sucker ring dentition,and color).Identifying squid based on statolith morphology is considered more accurate than identifying species based on beaks or gladius *** report and compare the statolith shape offive commercially Loliginidae squid(uroteuthis(Photololigo)duvaucelii,***,***,Loliolus beka,***)to determine how well these structures discriminate *** on statolith morphology,variation in the lateral and dorsal domes enables an 84.8%success rate at classifying *** factors correlate with statolith shape,and for vertically migrating squid,statolith relative size decreases with increased depth of *** morphology can be used to effectively and accurately identify species of Loliginidae squid occurring in Chinese waters,and may prove valuable for identifying and managing squid resources.

关键词： statolith shape analysis Loliginidae squid fishery management Chinese waters

Physical understanding of axonal growth patterns on grooved substrates:groove ridge crossing versus longitudinal alignment

在线全文

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2020年第4期3卷 348-360页

作者： Deming Zhang Hairui Suo Jin Qian Jun Yin jianzhong Fu Yong Huang The State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310028China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province School of Mechanical EngineeringZhejiang UniversityHangzhou 310028China School of Automation Hangzhou Dianzi UniversityHangzhou 310018China Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Department of Engineering MechanicsZhejiang UniversityHangzhou 310027China Department of Mechanical and Aerospace Engineering University of FloridaGainesvilleFL 32611USA

Surface topographies such as micrometric edges and grooves have been widely used to improve neuron ***,finding the mechanism of neuron–surface interactions on grooved substrates remains a *** this work,PC12 cells and chick forebrain neurons(CFNs)were cultured on grooved and smooth polyacrylonitrile *** was found that CFNs showed a tendency of growing across groove ridges;while PC12 cells were only observed to grow in the longitudinal direction of *** further investigate these observations,a 3D physical model of axonal outgrowth was *** this model,axon shafts are simulated as elastic 3D beams,accounting for the axon outgrowth as well as the focal contacts between axons and ***,the bending direction of axon tips during groove ridge crossing is governed by the energy minimization *** physical model predicts that axonal groove ridge crossing is contributed by the bending compliance of axons,caused by lower Young’s modulus and smaller *** work will aid the understanding of the mechanisms involved in axonal alignment and elongation of neurons guided by grooved substrates,and the obtained insights can be used to enhance the design of instructive scaffolds for nerve tissue engineering and regeneration applications.

关键词： Grooved substrates Neuron outgrowth Axonal outgrowth model Axonal crossing

Evolutionary trace analysis of eukaryotic DNA topoisomerase I superfamily:Identification of novel antitumor drug binding site

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2005年第4期48卷 375-384页

作者： SONG Yunlong QI Yunpeng ZHANG Wannian SHENG Chunquan ZHANG Min YAO jianzhong Yu Jianxin MIAO Zhenyuan ZHOu Youjun ZHu Ju L(u)Jiaguo Department of Medicinal Chemistry School of PharmacySecond Military Medical UniversityShanghai 200433China

The studies of novel inhibitors of DNA topoisomerase I(Topo I)have already be-come very promising in cancer *** the new drug-binding residues is playing an important role in the design and optimization of Topo I *** designed com-pounds may have novel scaffolds,thus will be helpful to overcome the toxicities of current camptothecin(CPT)drugs and may provide a solution to cross resistance with these ***-tiple sequence alignments were performed on eukaryotic DNA topoisomerase I superfamily and thus the evolutionary tree was *** Evolutionary Trace method was applied to iden-tify functionally important residues of human Topo *** has been demonstrated that class-specific hydrophobic residues Ala351,Met428,Pro431 are located around the 7,9-position of CPT,indi-cating suitable substitution of hydrophobic group on CPT will increase antitumor *** conservative residue Lys436 in the superfamily is of particular interest and new CPT derivatives designed based on this residue may greatly increase water solubility of such *** has also been demonstrated that the residues Asn352 and Arg364 were conservative in the superfamily,whose mutation will render CPT *** our molecular docking studies demonstrated they did not make any direct interaction with CPT,they are important drug-binding site residues for future design of novel non-camptothecin lead *** work provided a strong basis for the design and synthesis of novel highly potent CPT derivatives and virtual screening for novel lead compounds.

关键词： topoisomerase I binding site evolutionary trace camptothecin antineoplastic drugs.

国内外废弃矿井资源化利用现状与关键技术研究

在线全文

学校读者我要写书评

暂无评论

矿业研究与开发 2024年第5期44卷 174-184页

作者：张佳启赵国贞刘少炜张普纲赵建忠太原理工大学矿业工程学院山西太原030024 太原理工大学原位改性采矿教育部重点实验室山西太原030024 山西省交通新技术发展有限公司山西太原030024

废弃矿井的处置是能源环境领域面临的一大关键问题,严重影响着全球资源开发与环境保护协调发展。为了更好地利用矿井废弃后遗留的大量资源,介绍了国内外废弃矿井现状以及废弃矿井资源化利用现状与特点,简述了废弃矿井的潜在危害,阐述了... 详细信息

废弃矿井的处置是能源环境领域面临的一大关键问题,严重影响着全球资源开发与环境保护协调发展。为了更好地利用矿井废弃后遗留的大量资源,介绍了国内外废弃矿井现状以及废弃矿井资源化利用现状与特点,简述了废弃矿井的潜在危害,阐述了废弃矿井综合利用的内涵与关键科学问题,探讨了废弃矿井地热能开发利用、地下水资源精准利用、建设地下储气库等关键技术,指明了废弃矿井地热能资源勘察评估、地下水库煤柱坝体稳定性以及储水能力计算、地下储气库选址的技术难点,提出了废弃矿井资源化利用思路。研究表明,废弃矿井资源化综合利用在废弃矿井转型与可持续发展等方面具有广阔应用前景,可促进我国资源枯竭型城市转型发展。

关键词：废弃矿井地下可再生资源开发利用地下空间资源利用可持续发展

A Generic Data Analytics System for Manufacturing Production

在线全文

学校读者我要写书评

暂无评论

大数据挖掘与分析(英文) 2018年第2期1卷 160-171页

作者： Hao Zhang Hongzhi Wang jianzhong Li Hong Gao with the Department of Computer Science and Technology Harbin Institute of Technology

The increase in the amount of manufacturing information available means that big data can be collected and, with appropriate deep analysis, could be of great value to manufacturers. However, most small manufacturers cannot afford the overhead of a professional data analytics team. To address this problem, in this paper a generic data analytics system, Generic Manufacturing Data Analytics system(GMDA), is proposed. This system can perform most manufacturing data analytics tasks and users can easily carry out data analysis even if they have no prior knowledge or experience of data analytics. To establish such a system, we designed an abstract language,GMDL, to describe the manufacturing data analytics tasks. Aimed at factory data analytics, several algorithms were selected, tuned, optimized, and finally integrated into the system. Some noteworthy techniques were developed in GMDA such as proper algorithm selection strategy and an optimal parameter determination algorithm. Case studies show the practicability and reliability of the system.

关键词： manufactory data analytics data mining optimization

Lunar absolute reflectance as observed by Chang'E-1 Imaging Interferometer

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2015年第8期58卷 102-107页

作者： ZHANG Jiang LING ZongCheng LIu jianzhong Wu ZhongChen LI Bo NI YuHeng School of Physics Shandong University Institute of Space Sciences Shandong University Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment School of Space ScienceShandong University Institute of Geochemistry Chinese Academy of Sciences

Lunar absolute reflectance, which describes the fraction of solar radiation reflected by the Moon, is fundamental for the Chang'E-1 Imaging Interferometer(IIM) to map lunar mineralogical and elemental distributions. Recent observations made by the Spectral Irradiance Monitor(SIM) onboard the Solar Radiation and Climate Experiment(SORCE) spacecraft indicate that temporal variation in the solar radiation might have non-negligible influence on reflectance calculation, and the SIM measurements are different from the two previously used solar irradiances, i.e., ATLAS3 and Newkur. To provide reliable science results, we examined solar irradiance variability with the SIM daily observations, derived lunar absolute reflectances from the IIM 2A radiance with the SIM, ATLAS3 and Newkur data, and compared them with the Chandrayaan-1 Moon Mineralogy Mapper(M3), the Robotic Lunar Observatory(ROLO) and the Kaguya Multispectral Imager(MI) results. The temporal variability of the SIM solar irradiance is 0.25%–1.1% in the IIM spectral range, and less than 0.2% during the IIM observations. Nevertheless, the differences between the SIM measurements and the ATLAS3 and Newkur data can respectively rise up to 8% and 5% at particular IIM bands, resulting in discrepancy between which might affect compositional mapping. The IIM absolute reflectance we derived for the Moon using the SIM data, except for the last two bands, is consistent with the ROLO and the MI observations, although it is lower.

关键词： Chang'E-1 Imaging Interferometer (IIM) absolute reflectance solar irradiance

Rapid assembling organ prototypes with controllable cell-laden multi-scale sheets

在线全文

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2019年第1期2卷 1-9页

作者： Qing Gao Peng Zhao Ruijian Zhou Peng Wang jianzhong Fu Yong He Slate Key Laboratory of Fluid Power and Mechatronic Systems. School of Mechanical Engineering. Zhejiang university. Hangzhou 310027. China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province. School of Mechanical Engineering Zhejiang University Hangzhou 310027 China

A native organ has heterogeneous structures, sirength, and cell components. It is a big challenge to fabricate organ prototypes with controllable shapes, strength, and cells. Herein, a hybrid method is developed to fabricate organ prototypes with controlled cell deposition by integrating extrusion-based 3D printing, electrospinning, and 3D bioprinting. Multi-scale sheets were first fabricated by 3D printing and electrospinning;then, all the sheets were assembled into organ prototypes by sol-gel react io n duri ng bioprinting. With this method, macroscale structures fabricated by 3D printing ensure the customized structures and provide mechanical support, nanoscale structures fabricated by electrospinning offer a favorable environment for cell growth, and different types of cells with controllable densities are deposited in accurate locations by bioprinting. The results show that L929 mouse fibroblasts encapsulated in the structures exhibited over 90% survival within 10 days and maintai ned a high proliferation rate. Furthermore, the cells grew in spherical shapes first and then migrated to the nano scale fibers showing stretched morphology. Additionally, a branched vascular structure was successfully fabricated using the presented method. Compared with other methods, this strategy offers an easy way to simultancously realize the shape control, nanolibrous structures, and cell accurate deposition, which will have potemidi applications in tissue cngineering.

关键词： Organ prototypes 3D printing Electrospinning 3D bioprinting Multi-scale sheets