检索结果-南通市图书馆

高职院校护理专业“岗课赛证”综合育人路径的探索与实践

在线全文

学校读者我要写书评

暂无评论

中华护理教育 2024年第7期21卷 834-840页

作者：王秀蓉王娜娜蒋会慧亳州职业技术学院安徽省亳州市236800 广州市老人院护理部广州市510550

“岗课赛证”融合育人是培养高素质技术技能人才的有效模式,是推进新时代职业教育高速高质量发展的重要举措。亳州职业技术学院立足地方特色、把握护理专业特点,深入探索“岗课赛证”综合育人内涵,通过思政引领育人、优化课程结构与资... 详细信息

“岗课赛证”融合育人是培养高素质技术技能人才的有效模式,是推进新时代职业教育高速高质量发展的重要举措。亳州职业技术学院立足地方特色、把握护理专业特点,深入探索“岗课赛证”综合育人内涵,通过思政引领育人、优化课程结构与资源、优化师资队伍建设、推进“岗课赛证”融通、实施多元综合考评,持续推进“岗课赛证”综合育人,可为“一专多能”的复合型护理人才培养提供借鉴。

关键词：职业教育 “岗课赛证”融通护理教育改革综合育人

表观遗传修饰调控相分离在神经发育和神经疾病发生中的作用

在线全文

学校读者我要写书评

暂无评论

军事医学 2024年第2期48卷 148-153页

作者：刘贺丽姜慧慧吴海涛南华大学衡阳医学院军事科学院军事医学研究院研究生协作培养基地湖南衡阳421001 军事科学院军事医学研究院军事认知与脑科学研究所北京100850

近年来生物大分子的液-液相分离在一系列生物学过程中的重要作用已被广泛接受,包括基因的转录和翻译调控、应激反应、自噬以及突触结构的建立等。异常的相分离与多种人类疾病相关,包括神经发育失调和神经退行性疾病。研究表明,与表观遗... 详细信息

近年来生物大分子的液-液相分离在一系列生物学过程中的重要作用已被广泛接受,包括基因的转录和翻译调控、应激反应、自噬以及突触结构的建立等。异常的相分离与多种人类疾病相关,包括神经发育失调和神经退行性疾病。研究表明,与表观遗传修饰相关的一些蛋白也表现出液-液相分离的特征,暗示了表观遗传修饰可能通过调控相分离来调控神经发育和神经疾病。该文概括了表观遗传修饰和相分离在神经发育和疾病中的重要作用,并重点关注表观遗传修饰调控相分离在神经发育和疾病中的重要作用。结合表观遗传修饰和相分离将有助于深入理解神经发育和疾病发生的机制,并进一步为相关疾病的治疗提供新的靶点和策略。

关键词：表观遗传修饰液-液相分离生物凝聚体神经发育神经疾病

在线全文

学校读者我要写书评

暂无评论

避免电压瞬降对设备影响的技术研究

山西电子技术 2024年第2期 120-122页

作者：姜慧慧高智刚中电科风华信息装备股份有限公司山西太原030024

主要阐述了什么是SEMI F47电压瞬降,SEMI F47的标准曲线及测试特性规范,如何预防电压瞬降的技术措施,通过一系列措施的改进、参数设置、线路改进等使设备具有应对电压瞬降的能力,保证设备正常运行。

关键词： SEMI F47 电压瞬降预防措施

High level expression of Saccharomyces cerevisiae chitinase(ScCTS1)in Pichia pastoris for degrading chitin

在线全文

学校读者我要写书评

暂无评论

International Journal of Agricultural and Biological Engineering 2015年第5期8卷 142-150页

作者： Zhao Youxi jiang huihui Rao Zhiming Ji Yizhi Cheng Yanling Ma Yanhe Key Laboratory of Industrial Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China Beijing Key Laboratory of Biomass Waste Resource Utilization Biochemical Engineering CollegeBeijing Union UniversityBeijing 100023China State Key Laboratory of Microbial Resources Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China

Chitin is the second most abundant renewable biopolymer in the *** play important roles in the degradation of *** are produced by different organisms for different purposes,which are widely expressed in the three domains of life,ranging from archaea,bacteria,to fungi,yeasts,plants,insects,and even *** there are few reports about Saccharomyces cerevisiae chitinase(ScCTS1).The aim of this study was to realize the high level expression of *** ScCTS1 was cloned into the expression vector *** recombinant plasmid was linearized and transformed into competent Pichia pastoris *** screening by G418 plate,the fermentation conditions were ***,under the optimal fermentation conditions,ScCTS1 enzymatic activity reached up to 94.6 U/*** paper presents the first report on the heterologous expression of a full-length ScCTS1 with considerably high *** work will not only make a great stride towards its potential applications in biotechnology,but also facilitate elucidating the precise mechanism of yeast cell division.

关键词： chitinases heterologous expression Saccharomyces cerevisiae pichia pastoris biotechnology

基于PLC的高内聚低耦合软件架构设计方法研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

电子工业专用设备 2024年第3期53卷 60-63页

作者：高智刚姜慧慧田辉容烁中电科风华信息装备股份有限公司山西太原030032

PLC的编程方式逐渐由传统的梯形图编程升级到了基于OOP(面向对象)的模块化编程,虽然提高了程序编写的效率,但依然未形成架构设计的概念和遵循架构设计下的编程规范,导致团队赋能缺失,严重依赖个人能力,给项目运行带来不可追溯和不可预... 详细信息

PLC的编程方式逐渐由传统的梯形图编程升级到了基于OOP(面向对象)的模块化编程,虽然提高了程序编写的效率,但依然未形成架构设计的概念和遵循架构设计下的编程规范,导致团队赋能缺失,严重依赖个人能力,给项目运行带来不可追溯和不可预知的风险。“高内聚低耦合”的软件架构设计方法,重新定义了产品的研发模式;实现了从依赖个人能力、随机化和偶然性推出成功产品,到为团队赋能、制度化和持续性推出高质量产品的转变。

关键词：架构高内聚低耦合团队赋能架构设计文档

Liquid–liquid phase separation in synaptopathies

在线全文

学校读者我要写书评

暂无评论

Neuroprotection 2023年第1期1卷 34-45页

作者： huihui jiang Haitao Wu Department of Neurobiology Beijing Institute of Basic Medical SciencesBeijingChina Chinese Institute for Brain Research BeijingChina Key Laboratory of Neuroregeneration Co‐innovation Center of NeuroregenerationNantong UniversityNantongJiangsuChina

Liquid–liquid phase separation has emerged as an important mechanism for regulating cell activity by promoting the formation of membrane-less *** the nervous system,the formation of distinct molecular condensates via phase separation is involved in synaptic assembly and *** of phase separation is associated with several disease states,such as cancer,neurodegenerative disorders,and neurodevelopmental *** review summarizes the function of phase separation in the assembly and plasticity of the synapse,discusses the role of abnormal phase separation in neurological diseases,and proposes potential treatment options for these neurological diseases based on phase separation.

关键词： neurodegenerative disorder neurodevelopmental disorder phase separation synapse synaptopathy

Effects of Panax Notoginseng Saponin on the Expression of Vascular Endothelial Growth Factor after the Brain Ischemia-reperfusion Injury in Rats

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

长江大学学报（自科版）（下旬） 2015年第4期12卷 I0001-I0003页

作者： jiang huihui Wang Yuanyuan Hu Donghua jiang Rongyan Departrnentof Pharmacology AnhuiMedical University Hefei 230032 China Departmentof pharmacy BozhouVocational and Technical College Bozhou 236800 China Department of pharmacy Bozhou Vocational and Technical College Bozhou 236800 China Department of Pharmacology Anhui Medical University Hefei 230032 China Department of Cardiovascular Medicine Peoplgs Hospital of Bozhou City Bozhou 236800 China

Objective： To observe effects of Panax Notoginseng Saponin （PSN） on the expression of Vascular Endothelial Growth Factor （VEGF） after the brain ischemia-reperfusion injury in rats. Methods： 48 SD rats had been randomly divided into 4 groups： the sham operation group, the model group, Panax Notoginseng Saponin （PNS） group and Nimodipine group （n=12） . The rats had been treated with PNS, and 7 days later the rat focal cerebral ischemia-reperfusion models had been pre- pared. Neurobehavioral scores （NBS） had been evaluated in each group, TTC staining observed; the immunohistochemistry was used to observe VEGF and mRNA expressions. Results： PNS could not only improve significantly neurobehavioral scores and decrease dramatically cerebral infarct volume, but also increase remarkably VEGF and mRNA expression levels. Conclusion： The PNS is beneficial for rehabilitation after cerebral ischemia reperfusion injury via effectively up-regulating the injured cor- tical VEGF mRNA expression concentrations, which promotes vascular reborn in the ischemic region.

关键词： Panax notoginseng saponin Brain ischemia Reperfusion injury vascular endothelialgrowth factor (VEGF)

Defective Nickel-Iron Layered Double Hydroxide for Enhanced Photocatalytic NO Oxidation with Significant Alleviation of NO2 Production

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2024年第5期36卷 276-284页

作者： Xiaoyu Li Xiaoshu Lv Jian Pan Peng Chen huihui Peng Yan jiang Haifeng Gong Guangming jiang Li’an Hou Engineering Research Center for Waste Oil Recovery Technology and Equipment Ministry of EducationChongqing Technology and Business UniversityChongqing 400067China State Key Laboratory of Water Environment Simulation School of EnvironmentBeijing Normal UniversityBeijing 100875China Environmental Technology Innovation Center of Jiande Hangzhou Bertzer Catalyst Co.Ltd.Hangzhou 310058China Chongqing Key Laboratory of Green Synthesis and Application College of ChemistryChongqing Normal UniversityChongqing 401331China

Photocatalysis offers a sustainable means for the oxidative removal of low concentrations of NOx(NO,NO2,N2O,N2O5,etc.)from the *** double hydroxides(LDHs)are promising candidate photocatalysts owing to their unique layered and tunable chemical structures and abundant surface hydroxide(OH)moieties,which are hydroxyl radical(OH)***,the practical applications of LDHs are limited by their poor charge-separation ability and insufficient active ***,we developed a facile N_(2)H_(4)-driven etching approach to introduce dual Ni^(2+)and OHvacancies(Niv and OHv,respectively)into NiFe-LDH nanosheets(hereafter referred to as NiFe-LDH-et)to facilitate improved charge-carrier separation and active Lewis acidic site(Fe^(3+)and Ni^(2+)exposed at OHv)*** contrast to inert pristine LDH,NiFe-LDH-et actively removed NO under visible-light ***,Ni_(76)Fe_(24)-LDH-et etched with 1.50 mmol·L^(-1)N_(2)H_(4)solution removed 32.8%of the NO in continuously flowing air(NO feed concentration:500 parts per billion(ppb))under visible-light illumination,thereby outperforming most reported *** and theoretical data revealed that the dual vacancies promoted the production of reactive oxygen species(O_(2)·^(-)andOH)and the adsorption of NO on the *** situ spectroscopy demonstrated that NO was preferentially adsorbed at Lewis acidic sites,particularly exposed Fe^(3+)sites,converted into NO+,and subsequently oxidized to NO3without the notable formation of the more toxic intermediate NO2,thereby alleviating risks associated with its production and emission.

关键词： Vacancie Layered double hydroxide NO+ Photocatalysis NO removal

共享应用支撑平台的研究及其在学位论文系统中的应用

在线全文

学校读者我要写书评

暂无评论

现代图书情报技术 2008年第11期 13-18页

作者：蒋慧珲马自卫北京邮电大学计算机学院北京100876 北京邮电大学图书馆北京100876

通过对数字图书馆应用系统的分析,提出建设共享应用支撑平台的思路并详细介绍共享应用支撑平台的功能结构及服务框架。在此基础上,以学位论文系统为例,介绍该系统如何利用共享应用平台来实现其功能。

关键词：共享平台学位论文系统