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Journal of Materials Science & Technology 2023年第15期146卷 154-167页

作者： Pengfei Dang jianbo pang Yumei Zhou Lei Ding Lei Zhang Xiangdong Ding Turab Lookman Jun Sun Dezhen Xue State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an 710049China AiMaterials Research LLC Santa FeNM 87501USA

Functional stability of superelasticity is crucial for practical applications of shape memory *** is degraded by a Lüders-like deformation with elevated local stress concentration under tensile *** increasing the degree of solute supersaturation and applying appropriate thermomechanical treatments,a Ti-Ni alloy with nanocrystallinity and dispersed nanoprecipitates is *** contrast to conventional Ti-Ni alloys,the superelasticity in the target alloy is accompanied by homogeneous deformation due to the sluggish stress-induced martensitic *** alloy thus shows a fully recoverable strain of 6%under tensile stress over 1 GPa and a large adiabatic temperature decrease of 13.1 K under tensile strain of 4.5%at room ***,both superelasticity and elastocaloric effect exhibit negligible degradation in response to applied strain of 4%during *** attribute the improved functional stability to low dislocation activity resulting from the suppression of localized deformation and the combined strengthening effect of nanocrystalline structure and ***,the design of such a microstructure enabling homogeneous deformation provides a recipe for stable superelasticity and elastocaloric effect.

关键词： Ti-Ni alloys Superelasticity Elastocaloric effect Martensite band Functional stability

Temperature-field history dependence of the elastocaloric effect for a strain glass alloy

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Journal of Materials Science & Technology 2022年第8期103卷 8-14页

作者： Deqing Xue Ruihao Yuan Yuanchao Yang jianbo pang Yumei Zhou Xiangdong Ding Turab Lookman Xiaobing Ren Jun Sun Dezhen Xue State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an 710049China School of Materials Science and Engineering Xi’an University of TechnologyXi’an 710048China AiMaterials Research Santa FeNew Mexico 87501USA Ferroic Physics Group National Institute for Materials ScienceTsukuba 305-0047IbarakiJapan

The singular change of the order parameter at the first order martensitic transformation(MT)temperature restricts the caloric response to a narrow temperature *** the MT is tuned into a sluggish strain glass transition by defect doping and a large elastocaloric effect appears in a wide temperature ***,an inverse elastocaloric effect is observed in the strain glass alloy with history of zerofield cooling and is attributed to the slow dynamics of the nanodomains in response to the external *** study offers a design recipe to expand the temperature range for good elastocaloric effect.

关键词： Elastocaloric effect Isothermal entropy change Strain glass

徽州文化生态保护区研究进展--基于CiteSpace的文献可视化分析

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黄山学院学报 2024年第2期26卷 1-7页

作者：郭延龙庞建波安徽省社会科学院安徽合肥230601 安徽大学艺术学院安徽合肥230601

以中国知网数据库为样本来源,对有关徽州文化生态保护区的文献进行整理与分析,结合CiteSpace的科学计算与可视化方法,从发文时间、作者和单位、关键词共现方式、关键词时间线图等对1995年1月-2022年8月徽州文化生态保护区研究成果展开分... 详细信息

以中国知网数据库为样本来源,对有关徽州文化生态保护区的文献进行整理与分析,结合CiteSpace的科学计算与可视化方法,从发文时间、作者和单位、关键词共现方式、关键词时间线图等对1995年1月-2022年8月徽州文化生态保护区研究成果展开分析,发现徽州文化生态保护区的建立促进了地方文化、社会经济的迅速发展,为地方文化的保存和弘扬带来了积极的社会效益。

关键词：徽州文化生态保护区 CiteSpace 可视化

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安徽宣纸制作技艺的传承与保护问题研究

上海视觉 2022年第2期 29-34页

作者：郭延龙庞建波安徽大学艺术学院合肥230601

宣纸是传统手工造纸技艺的重要代表,是文化知识的重要载体,承载着传播中华文明的历史使命。本文通过文献研究法和实地考察法,从宣纸制作技艺传承与保护的现状、问题展开调查与分析,从传承人群、市场和政府三个维度,提出了宣纸制作技艺... 详细信息

宣纸是传统手工造纸技艺的重要代表,是文化知识的重要载体,承载着传播中华文明的历史使命。本文通过文献研究法和实地考察法,从宣纸制作技艺传承与保护的现状、问题展开调查与分析,从传承人群、市场和政府三个维度,提出了宣纸制作技艺传承与保护的对策,得出传承人群需要活态传承宣纸制作技艺,主动激活传承机制,积极面对市场与时俱进的变化形式,政府层面需要助推传承人群培养,促进宣纸制作技艺的传承与保护。

关键词：宣纸非物质文化遗产传承保护

APPLICATION OF SUPERCRITICAL CO2 IN CONTROLLED RELEASE SYSTEM OF ORTHO-HYDROXYBENZOIC ACID WITH POLY(ε-CAPROLACTONE)

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APPLICATION OF SUPERCRITICAL CO2 IN CONTROLLED RELEASE SYSTE...

Interannual variability of boreal summer intraseasonal oscillation over the northwestern Pacific influenced by the Pacific Meridional Mode

Third East Asian Polymer Conference

作者： Qun Xu, Zhenzhong Hou, Qi Peng, Maizhi pang and jianbo Li College of Materials Engineering, Zhengzhou University, Zhengzhou 450052, P. R. China

In recent years, the strategy of using supercritical fluid (SCF) technology for crystal and particle engineering of pharmaceutical materials and drug delivery systems has been showing great promise. Supercritical precipitation or crystallization of drug and incorporation of drugs in a carrier using SCF has also become of interests. And these processes include rapid expansion of supercritical solutions (RESS), the batch and continuous gas anti-solvent (GAS) process and supercritical solution impregnation (SSI), even recently the solution enhanced dispersion by supercritical fluid (SEDS) used by A. M. Juppo, *** this paper, poly (ε-caprolactone) (PCL) was used to prepare a new type of controlled release system, i.e., a model drug ortho-hydroxybenzoic acid was impregnated into the biocompatible and biodegradable polymer

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 6-11页

作者： Haoyu Zhou pang-Chi Hsu Lin Chen Yitian Qian Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environmental Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjingChina

During the boreal summer,intraseasonal oscillations exhibit significant interannual variations in intensity over two key regions:the central-western equatorial Pacific(5°S-5°N,150°E-150°W)and the subtropical Northwestern Pacific(10°-20°N,130°E-175°W).The former is well-documented and considered to be influenced by the ENSO,while the latter has received comparatively less attention and is likely influenced by the Pacific Meridional Mode(PMM),as suggested by partial correlation analysis *** elucidate the physical processes responsible for the enhanced(weakened)intraseasonal convection over the subtropical northwestern Pacific during warm(cold)PMM years,the authors employed a moisture budget *** findings reveal that during warm PMM years,there is an increase in summer-mean moisture over the subtropical northwestern *** increase interacts with intensified vertical motion perturbations in the region,leading to greater vertical moisture advection in the lower troposphere and consequently resulting in convective *** a process is pivotal in amplifying intraseasonal convection *** observational findings were further verified by model experiments forced by PMM-like sea surface temperature patterns.

关键词： Boreal summer intraseasonal oscillation Interannual variability Pacific Meridional Mode Moisture budget analysis

非清髓自体外周造血干细胞与单次异体脐带间充质干细胞移植治疗1型糖尿病的疗效与安全性比较

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中华糖尿病杂志 2023年第3期15卷 229-235页

作者：庞建波陆婧沈山梅张溦李莉蓉毕艳朱大龙徐州医科大学鼓楼临床学院内分泌科南京210008 苏州卫生职业技术学院临床医学院苏州215151

目的探讨非清髓自体外周造血干细胞(HSC)与单次异体脐带间充质干细胞(MSC)移植治疗1型糖尿病(T1DM)患者的疗效和安全性差异。方法为回顾性病例对照研究。选取2006年8月至2010年12月于徐州医科大学鼓楼临床学院内分泌科接受HSC移植的T1D... 详细信息

目的探讨非清髓自体外周造血干细胞(HSC)与单次异体脐带间充质干细胞(MSC)移植治疗1型糖尿病(T1DM)患者的疗效和安全性差异。方法为回顾性病例对照研究。选取2006年8月至2010年12月于徐州医科大学鼓楼临床学院内分泌科接受HSC移植的T1DM患者9例及MSC移植的患者8例作为研究对象,筛选同时期仅接受常规胰岛素治疗且临床特征相匹配的T1DM患者10例作为对照。收集患者移植前及移植后12个月的胰岛素注射剂量、糖化血红蛋白(HbA_(1c))、空腹C肽(FCP)及餐后2 h C肽(2hCP),并计算各指标的变化幅度。将患者移植后12个月的血清FCP和(或)2hCP较移植前增加10%以上定义为临床缓解。观察两种干细胞移植过程中及随访期间患者不良反应的发生情况以判断其安全性。采用t检验或单因素方差分析、Mann‐Whitney U检验或Kruskal-Wallis H检验、Fisher精确检验进行组间比较。结果移植后12个月,HSC移植组、MSC移植组和对照组达到临床缓解的占比分别为7/9、2/8和1/10,HSC移植组临床缓解的占比高于对照组(P=0.005);3组的HbA_(1c)分别为(6.5±1.3)%、(7.7±1.5)%和(9.2±3.5)%;HSC移植组胰岛素注射剂量的下降幅度、FCP的增高幅度均大于对照组,且其2hCP的增高幅度大于MSC移植组和对照组(P<0.05)。HSC移植组有2例患者脱离胰岛素,MSC移植组和对照组均无患者脱离胰岛素。与移植前相比,移植后12个月HSC移植组的HbA_(1c)(t=-3.85,P=0.008)和胰岛素注射剂量(t=-2.47,P=0.039)均下降,而2hCP(Z=-2.07,P=0.039)升高;MSC移植组HbA_(1c)(t=-3.11,P=0.017)和2hCP(Z=-2.38,P=0.016)均下降。安全性方面,HSC移植组患者均发生轻度不良反应,而MSC移植组患者无不良反应发生。结论两种干细胞技术均有助于改善T1DM患者血糖及保护胰岛功能,HSC移植在改善胰岛功能疗效方面有优于MSC移植的趋势,而MSC移植安全性更高。

关键词：糖尿病,1型造血干细胞间充质干细胞移植

Cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage

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Neural Regeneration Research 2025年第4期20卷 1015-1030页

作者： Ruoyu Huang Qiuyu pang Lexin Zheng Jiaxi Lin Hanxi Li Lingbo Wan Tao Wang Department of Forensic Science School of Basic Medicine and Biological SciencesSuzhou Medicine College of Soochow UniversitySuzhouJiangsu ProvinceChina

Cholesterol is an important component of plasma membranes and participates in many basic life functions,such as the maintenance of cell membrane stability,the synthesis of steroid hormones,and *** plays a key role in the establishment and maintenance of the central nervous *** brain contains 20%of the whole body’s cholesterol,80%of which is located within myelin.A huge number of processes(e.g.,the sterol regulatory element-binding protein pathway and liver X receptor pathway)participate in the regulation of cholesterol metabolism in the brain via mechanisms that include cholesterol biosynthesis,intracellular transport,and *** brain injuries or diseases involving crosstalk among the processes above can affect normal cholesterol metabolism to induce detrimental ***,we hypothesized that cholesterol-related molecules and pathways can serve as therapeutic targets for central nervous system *** hemorrhage is the most severe hemorrhagic stroke subtype,with high mortality and *** cholesterol levels are associated with the risk of intracerebral ***,secondary pathological changes after intracerebral hemorrhage are associated with cholesterol metabolism dysregulation,such as neuroinflammation,demyelination,and multiple types of programmed cell *** cholesterol accumulation in the brain has been found after intracerebral *** this paper,we review normal cholesterol metabolism in the central nervous system,the mechanisms known to participate in the disturbance of cholesterol metabolism after intracerebral hemorrhage,and the links between cholesterol metabolism and cell *** also review several possible and constructive therapeutic targets identified based on cholesterol metabolism to provide cholesterol-based perspectives and a reference for those interested in the treatment of intracerebral hemorrhage.

关键词： cell death cholesterol metabolism intracerebral hemorrhage myelination therapeutic target

Collaborative City Digital Twin for the COVID-19 Pandemic:A Federated Learning Solution

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Tsinghua Science and Technology 2021年第5期26卷 759-771页

作者： Junjie pang Yan Huang Zhenzhen Xie jianbo Li Zhipeng Cai the College of Computer Science and Technology Qingdao UniversityQingdao 266000China the Business School Qingdao UniversityQingdao 266000China the College of Computing and Software Engineering Kennesaw State UniversityAtlantaGA 30060USA the College of Computer Science and Technology Jilin UniversityChangchun 130012China the Department of Computer Science Georgia State UniversityAtlantaGA 30303USA

The novel coronavirus,COVID-19,has caused a crisis that affects all segments of the *** the knowledge and understanding of COVID-19 evolve,an appropriate response plan for this pandemic is considered one of the most effective methods for controlling the spread of the *** studies indicate that a city Digital Twin(DT)is beneficial for tackling this health crisis,because it can construct a virtual replica to simulate factors,such as climate conditions,response policies,and people's trajectories,to help plan efficient and inclusive ***,a city DTsystem relies on long-term and high-quality data collection to make appropriate decisions,limiting its advantages when facing urgent crises,such as the COVID-19 *** Learning(FL),in which all clients can learn a shared model while retaining all training data locally,emerges as a promising solution for accumulating the insights from multiple data sources ***,the enhanced privacy protection settings removing the privacy barriers lie in this *** this work,we propose a framework that fused city DT with FL to achieve a novel collaborative paradigm that allows multiple city DTs to share the local strategy and status *** particular,an FL central server manages the local updates of multiple collaborators(city DTs),providing a global model that is trained in multiple iterations at different city DT systems until the model gains the correlations between various response plans and infection *** approach means a collaborative city DT paradigm fused with FL techniques can obtain knowledge and patterns from multiple DTs and eventually establish a"global view"of city crisis ***,it also helps improve each city's DT by consolidating other DT's data without violating privacy *** this paper,we use the COVID-19 pandemic as the use case of the proposed *** experimental results on a real dataset with various response plans val

关键词： COVID-19 Digital Twin(DT) Federated Learning(FL) deep learning

Gut microbiota-astrocyte axis: new insights into age-related cognitive decline

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Neural Regeneration Research 2025年第4期20卷 990-1008页

作者： Lan Zhang Jingge Wei Xilei Liu Dai Li Xiaoqi pang Fanglian Chen Hailong Cao Ping Lei Haihe Laboratory of Cell Ecosystem Department of GeriatricsTianjin Medical University General HospitalTianjinChina Tianjin Geriatrics Institute Tianjin Medical University General HospitalTianjinChina Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalNational Key Clinical SpecialtyTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjinChina Department of Urology Tianjin Medical University General HospitalTianjinChina Tianjin Neurological Institution Tianjin Medical University General HospitalTianjinChina

With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent *** is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of *** microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive *** article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative *** article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial ***,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s *** findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.

关键词： age aging Alzheimer’s disease astrocytes cognitive decline dementia gut microbiota gut–brain axis microbial metabolites neuroinflammation Parkinson’s disease