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Behavior of Element Vaporization and Composition Control of Fe-Ga Alloy during Vacuum Smelting

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Journal of Iron and Steel Research International 2015年第11期22卷 983-989页

作者： jian-wu yan Liang LUO A-fang PENG Chen-shu ZHANG Qing-hua CAO jiangxi Province Key Laboratory of Precision Drive and Control Institute of Micro/Nano Actuation and Control Nanchang Institute of Technology School of Aeronautical Manufacturing Engineering Nanchang Hangkong University

Saturated vapor pressure, critical evaporation temperature and evaporation loss rate of Fe-Ga alloy were calculated under different conditions of Ga and Fe contents with activity coefficients. The relationship between the change of Ga content and melting time was determined. The results demonstrated that saturated vapor pressure of Ga was higher than that of Fe under the same conditions. The difference value of critical evaporation temperature of Ga with and without Ar was nearly 800 K. The critical evaporation temperature of Fe was higher than that of Ga under vacuum, indicating that Ga was more volatile than Fe. At 1800 K, the evaporation rate of Ga was 84 times higher than that of Fe in the melt of Fe81Ga19 alloy. Under this condition, the change of Ga content and smelting time kept a linear relationship. The higher the temperature was, the faster the Ga content decreased, which was consistent with theoretical calculations.

关键词： Fe-Ga alloy vacuum smelting critical evaporation temperature saturated vapor pressure smelting time

Study of dynamic pressure roadway supporting scheme under condi- tion of thick composite roof

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Journal of Coal Science & Engineering(China) 2013年第2期19卷 119-125页

作者： Wei-Jun WANG Li-Qiang LUO Wei-jian YU Hai wu yan-Si QU Hunan Provincial Key Laboratory of Safe Mining Techniques of Coal Mines Hunan University of Science and TechnologyXiangtan 411201 China

This paper analyzed the strata behaviors of solid-coal roadway, gob-side entry driving and deformation law of surrounding rock in depth under high stress and thick composite roof based on the dynamic pressure roadway as engineering background in Fengcheng mining area, jiangxi province. The results, both field measurement and numerical simulation show that gob-side entry driving results the deformation of coal roadway main wall, however, entity-coal roadway driving results deformation of main roof and floor. The maintenance state of gob-side entry driving is better than entity-coal roadway, this situation is relevant to thick composite roof layered and easy collapse characteristics. At the same time, this paper put fox＇ward and proved proper dynamic pressure roadway supporting scheme under the surrounding rock condition and stress environment.

关键词： thick composite roof dynamic pressurized roadway high stress surrounding rock control

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu Liu Xiandeng Li Mi Li Xian wu Xiaohui Huang Ajing Xu yan Liu jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials

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Neural Regeneration Research 2025年第8期20卷 2245-2263页

作者： Run Song Shiyi Yin jiannan wu Junqiang yan Department of Neurology The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina Neuromolecular Biology Laboratory The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina

Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulatory mechanism for regulating neuronal aging and ***,excessive activation of regulated cell death may lead to the progression of aging-related *** review summarizes recent advances in the understanding of seven forms of regulated cell death in age-related ***,the newly identified ferroptosis and cuproptosis have been implicated in the risk of cognitive impairment and neurodegenerative *** forms of cell death exacerbate disease progression by promoting inflammation,oxidative stress,and pathological protein *** review also provides an overview of key signaling pathways and crosstalk mechanisms among these regulated cell death forms,with a focus on ferroptosis,cuproptosis,and *** instance,FDX1 directly induces cuproptosis by regulating copper ion valency and dihydrolipoamide S-acetyltransferase aggregation,while copper mediates glutathione peroxidase 4 degradation,enhancing ferroptosis ***,inhibiting the Xc-transport system to prevent ferroptosis can increase disulfide formation and shift the NADP^(+)/NADPH ratio,transitioning ferroptosis to *** insights help to uncover the potential connections among these novel regulated cell death forms and differentiate them from traditional regulated cell death *** conclusion,identifying key targets and their crosstalk points among various regulated cell death pathways may aid in developing specific biomarkers to reverse the aging clock and treat age-related neurodegenerative conditions.

关键词： apoptosis autophagy cuproptosis disulfidptosis ferroptosis necroptosis neurodegenerative disease neurological aging diseases PANoptosis pyroptosis

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福鼎大白茶树鲜叶不同茶制品活性成分比较

食品安全质量检测学报 2021年第8期12卷 3219-3223页

作者：黄彪刘文静吴建鸿吴建衍福建省农业科学院农业质量标准与检测技术研究所福州350003 福建省农产品质量安全重点实验室福州350003

目的分析比较福鼎大白茶树鲜叶加工制成的3种茶类中活性成分的含量差异。方法以福鼎大白茶树鲜叶为原料,按不同工艺制成绿茶、白茶、红茶,测定其活性成分(茶多酚、咖啡碱、氨基酸、儿茶素)含量。结果绿茶中茶多酚及儿茶素总量最高,红茶... 详细信息

目的分析比较福鼎大白茶树鲜叶加工制成的3种茶类中活性成分的含量差异。方法以福鼎大白茶树鲜叶为原料,按不同工艺制成绿茶、白茶、红茶,测定其活性成分(茶多酚、咖啡碱、氨基酸、儿茶素)含量。结果绿茶中茶多酚及儿茶素总量最高,红茶较低。绿茶中儿茶素总量约为红茶的10倍,白茶中儿茶素总量约为红茶的8倍;氨基酸含量:白茶高于绿茶及红茶,红茶中氨基酸最低;咖啡碱在白茶和绿茶中的含量差别不大,显著性高于红茶,但不存在极显著性差异。结论加工工艺对不同茶类茶多酚及儿茶素类物质含量影响较大,而对咖啡碱含量的影响不大。

关键词：福鼎大白茶多酚儿茶素咖啡碱

Clinical and Angiographic Predictors of Major Side Branch Occlusion after Main Vessel Stenting in Coronary Bifurcation Lesions

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Chinese Medical Journal 2015年第11期128卷 1471-1478页

作者： Dong Zhang Bo Xu Dong Yin Yi-Ping Li Yuan He Shi-Jie You Shu-Bin Qiao Yong-jian wu Hong-Bing yan Yue-Jin yang Run-Lin Gao Ke-Fei Dou Department of Cardiology State Key Laboratory of Cardiovascular Disease Cardiovascular Institute Fuwai Hospital and National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Background： Major side branch （SB） occlusion is one of the most serious complications during percutaneous coronary intervention （PCI） for bifurcation lesions. We aimed to characterize the incidence and predictors of major SB occlusion during coronary bifurcation intervention. Methods： We selected consecutive patients undergoing PCI （using one stent or provisional two stent strategy） for bifurcation lesions with major SB. All clinical characteristics, coronary angiography findings, PCI procedural factors and quantitative coronary angiographic analysis data were collected. Multivariate logistic regression analysis was performed to identify independent predictors of SB occlusion. SB occlusion after main vessel （MV） stenting was defined as no blood flow or any thrombolysis in myocardial infarction （TIMI） flow grade decrease in SB after MV stenting. Results： Among all 652 bifurcation lesions, 32 （4.91%） SBs occluded. No blood flow occurred in 18 lesions and TIMI flow grade decreasing occurred in 14 lesions. In multivariate analysis, diameter ratio between MV/SB （odds ratio [OR]： 7.71,95% confidence interval [C/]： 1.53-38.85, P = 0.01）, bifurcation angle （OR： 1.03, 95% CI： 1.02-1.05, P 〈 0.01）, diameter stenosis of SB before MV stenting （OR： 1.05, 95% CI： 1.03-1.07, P〈 0.01）, TIMI flow grade of SB before MV stenting （OR： 3.59, 95% CI： 1.48-8.72, P〈 0.01） and left ventricular eject fraction （LVEF）（OR： 1.06, 95% Cl： 1.02-1.11, P 〈 0.01） were independent predictors of SB occlusion. Conclusions： Among clinical and angiographic findings, diameter ratio between MV/SB, bifurcation angle, diameter stenosis of SB before MV stenting, TIMI flow grade of SB before MV stenting and LVEF were predictive of major SB occlusion after MV stenting.

关键词： Coronary Bifurcation Lesions Major Side Branch Occlusion Percutaneous Coronary Intervention

Acute effect of circumferential pulmonary vein isolation by catheter radiofrequency ablation on P-wave dispersion

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Acute effect of circumferential pulmonary vein isolation by ...

A grating-coupled external cavity InAs/InP quantum dot laser with 85-nm tuning range

第十三次全国心血管病学术会议

作者： LI Ping,XU yan,CHENG Xiao-shu,HU jian-xin,wu yan-qin,LI Ju-xiang, wu Qing-hua,YU jian-hua,CHEN Qi,HONG Kui,SU Hai Cardiovascular Department.2nd affiliated hospital of Nan Chang University, Nanchang 330006,China

Objective To observe the acute effect of successful circumferential pulmonary vein isolation per se by catheter radiofrequency ablation on P-wave *** 38 patients who were underwent three- dimensional electroanatomical mapping system(Ensite 3000 or Carto) guided circumferential pulmonary vein isolation by radiofrequency catheter ablations for paroxysmal atrial fibrillation from August 2007 to April 2010 in our hospital were included in this *** were 25 males and 13 females,aged from 34 to 74 years with a mean(59.60±8.35),in which 23 patients with hypertension,8

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来源： cnki会议评论

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Chinese Physics B 2013年第9期22卷 446-449页

作者：魏恒金鹏罗帅季海铭杨涛李新坤吴剑安琪吴艳华陈红梅王飞飞吴巨王占国 Key Laboratory of Semiconductor Materials Science and Beijing Key Laboratory of Low-dimensional Semiconductor Materials and Devices Institute of SemiconductorsChinese Academy of Sciences

The optical performance of a grating-coupled external Continuous tuning from 1391 nm to 1468 nm is realized at cavity laser based on InAs/InP quantum dots is investigated. an injection current of 1900 mA. With the injection current increasing to 2300 mA, the tuning is blue shifted to some extent to the range from 1383 nm to 1461 nm. By combining the effect of the injection current with the grating tuning, the total tuning bandwidth of the external cavity quantum-dot laser can reach up to 85 nm. The dependence of the threshold current on the tuning wavelength is also presented.

关键词： quantum dot external cavity tunable laser

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong wu Yushan Chen Zhen Wei Yufei Mei yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area