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Identifying sex-specific differences in the carotid revascularisation literature:findings from a scoping review

Stroke & Vascular Neurology 2021年第3期6卷 496-499,I0085-I0096页

作者： Vignan Yogendrakumar Michel Shamy Brian Dewar Dean A Fergusson Dar Dowlatshahi Candyce Hamel Sophia Gocan Mark Fedyk jean-louis Mas Peter Rothwell Virginia Howard Olena Bereznyakova On behalf of the WoW-CAD Investigators Department of Medicine Division of Neurology and Ottawa Hospital Research InstituteUniversity of OttawaOttawaOntarioCanada Epidemiology Program Ottawa Hospital Research InstituteOttawaOntarioCanada Stroke Prevention Clinic Ottawa HospitalOttawaOntarioCanada Bioethics Program UC Davis Department of MedicineSacramentoCaliforniaUSA Universite Paris Descartes Faculte de Medecine Site Cochin Parislle-de-FranceFrance Service de Neurologie Hôital Sainte-AnneParisFrance The University of Alabama at Birmingham School of Medicine BirminghamAlabamaUSA School of Public Health University of Alabama at BirminghamBirminghamAlabamaUSA 不详

Objective No systematic review of the literature has dedicated itself to looking at the management of symptomatic carotid stenosis in female *** this scoping review,we aimed to identify all randomised controlled trials(RCTs)that reported sex-specific outcomes for patients who underwent carotid revascularisation,and determine whether sufficient information is reported within these studies to assess short-term and long-term outcomes in female ***,setting and participants We systematically searched Medline,Embase,Pubmed and Cochrane libraries for RCTs published between 1991 and 2020 that included female patients and compared either endarterectomy with stenting,or any revascularisation(endarterectomy or stenting)with medical therapy in patients with symptomatic high-grade(>50%)carotid *** From 1537 references examined,27 eligible studies were ***-specific outcomes were reported in 13 *** patient characteristics of enrolled female patients were reported in 2 of those 13 *** outcomes reported included stroke and death,however,there was significant heterogeneity in the reporting of both periprocedural and long-term ***-specific differences relating to the degree of stenosis and time from index event to treatment are largely limited to studies comparing endarterectomy to medical *** events were not reported by *** Only half of the previously published RCTs and systematic reviews report sex-specific *** analyses on the results of carotid artery intervention for female patients with symptomatic stenosis are limited.

关键词： carotid stenosis finding

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On the cratonization of the Arabian-Nubian Shield: Constraints from gneissic granitoids in south Eastern Desert, Egypt

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Geoscience Frontiers 2021年第4期12卷 215-243页

作者： Ali A.Khudeir jean-louis Paquette Kirsten Nicholson Åke Johansson Tyrone O.Rooney Sadiq Hamid Mohamed A.El-Fadly Loretta Corcoran Shawn J.Malone Mohamed Ali Abu El-Rus Geology Department Faculty of ScienceAssiut University71516Egypt UniversitéClermont Auvergne CNRSIRDOPGCLaboratoire Magmas et VolcansF-63000 Clermont-FerrandFrance Ball-State University Department of EnvironmentGeology and Natural Resources117 Fine Art BuildingMuncieIN 47306USA Department of Geosciences Swedish Museum of Natural HistoryBox 50007SE-10405 StockholmSweden Department of Earth and Environmental Sciences Michigan-State UniversityEast LansingMI 48824USA Notre Dame University Department of Civil and Environmental Engineering and Earth Sciences156 Fitzpatrick HallNotre DameIN 46556USA

The Shaitian granite complex(SGC)spans more than 80 Ma of crustal growth in the Arabian–Nubian Shield in southeast *** is a voluminous composite intrusion(60 km2)comprising a host tonalite massif intruded by subordinate dyke-like masses of trondhjemite,granodiorite and *** host tonalite,in turn,encloses several,fine-grained amphibolite enclaves.U-Pb zircon dating indicates a wide range of crystallization ages within the SGC(800±18Ma for tonalites;754±3.9 Ma for trondhjemite;738±3.8 Ma for granodiorite;and 717±3.2 Ma for monzogranite),suggesting crystallization of independent magma *** high positiveεNdi(+6–+8)indicate that the melting sources were dominated by juvenile material without any significant input from older *** of zircon saturation geothermometry indicates increasing temperatures during the generation of melts from 745±31℃ for tonalite to 810±25℃ for trondhjemite;840±10℃ for granodiorite;and 868±10℃ for *** pressure of partial melting is loosely constrained to be below the stability of residual garnet(3 kbar for the stability of residual amphibole as inferred from the significantly lower NbN and TaN compared with LREEN and the sub-chondrite Nb/Ta ratios exhibited by the granitic *** inverse relation between the generation temperatures and the ages estimates of the granitoid lithologies argue against a significant role of fractional *** major and trace element contents indicate the emplacement of the SGC within a subduction zone *** lacks distinctive features for melt derived from a subducted slab(*** Sr/Y and high(La/Yb)N ratios),and the relatively low MgO and Ni contents in all granite phases within the SGC suggest melting within the lower crust of an island arc overlying a *** melts produced during melting experiments indicates an amphibolite of basaltic composition is th

关键词： Arabian-Nubian Shield(ANS) Cratonization Fractional crystallization Partial melting Subduction zones Tonalite-Trondhjemite-granodiorite(TTG)

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Spatial and Temporal Variations of Climate in Europe

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Atmospheric and Climate Sciences 2012年第4期2卷 568-581页

作者： Vladimir Kossobokov jean-louis Le Mouel Claude Allègre Institute of Earthquake Prediction Theory and Mathematical Geophysics Russian Academy of SciencesMoscowRussia Institut de Physique du Globe de Paris ParisFrance

Temperature series of the original individual measurements of the minimum and maximum daily temperatures from 24 stations located in different regions of Europe are considered with the objective of studying the stability or the variability of the “climate” in time and space. The patterns of the temperature statistics, the shapes of probability density functions, in particular, at different places and times allow comparisons based on the Kolmogorov-Smirnov test, the Shannon entropy, and cluster analysis, used separately or in combination for the purposes of quantitative climate classification.

关键词： Daily Air Temperature Climate Classification Empirical Distribution Function Entropy Cluster Analysis

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Annual and Diurnal Variabilities in the Critical Frequency (foF2) during Geomagnetic Fluctuating Activity over Solar Cycles 21 and 22 at Ouagadougou

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Atmospheric and Climate Sciences 2018年第4期8卷 435-445页

作者： Abidina Diabaté Frédéric Ouattara jean louis Zerbo Laboratoire de Recherche en Energétique et Météorologie de l’Espace (LAREME) Université Norbert Zongo Koudougou Burkina Faso Université Nazi Boni Bobo Dioulasso Burkina Faso Laboratoire d’Energies Thermiques Renouvelables (L.E.T.RE) Université Ouaga 1 Pr Joseph Ki-Zerbo Ouagadougou Burkina Faso

Geomagnetic activity is characterized by four solar wind conditions. Each condition has specific impact on ionosphere. This paper review on fluctuating activity effects on ionosphere F2 layer through its critical frequency foF2 variations. Under fluctuating wind conditions, we have investigated on annual, diurnal and seasonal variations of foF2 during solar cycles 21 and 22 phases covered by Ouagadougou ionosonde station data (Lat: 12.5°N;Long: 358.5°E;dip: 1.43°). Our investigations show that foF2 annual’ variability is in phase with solar cycle. The diurnal variation is “noon bite out” most of the time except for the solar maximum where we have a morning peak testifying to the fact that the vertical drift E × B is disturbed. The seasonal variations show that the fluctuating activity has no particular effect on certain characteristics of the equatorial ionosphere such as electrojet and vertical drift E × B. However, the increase of the electric field pre-reversal phenomenon in autumn is a characteristic effect observed during the fluctuating activity.

关键词： Critical Frequency Solar Cycle Seasonal Diurnal Fluctuating Activity

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Biosensors for Pesticide Detection: New Trends

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American Journal of Analytical Chemistry 2012年第3期3卷 210-232页

作者： Audrey Sassolas Beatriz Prieto-Simón jean-louis Marty Laboratoire IMAGES EA 4218 Université de Perpignan via Domitia Perpignan France Nanobioengineering Group Institute for Bioengineering of Catalonia Barcelone Spain

Due to the large amounts of pesticides commonly used and their impact on health, prompt and accurate pesticide analysis is important. This review gives an overview of recent advances and new trends in biosensors for pesticide detection. Optical, electrochemical and piezoelectric biosensors have been reported based on the detection method. In this review biosensors have been classified according to the immobilized biorecognition element: enzymes, cells, antibodies and, more rarely, DNA. The use of tailor-designed biomolecules, such as aptamers and molecularly imprinted polymers, is reviewed. Artificial Neural Networks, that allow the analysis of pesticide mixtures are also presented. Recent advances in the field of nanomaterials merit special mention. The incorporation of nanomaterials provides highly sensitive sensing devices allowing the efficient detection of pesticides.

关键词： Biosensors Pesticides

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Caffeoyl Derivatives: Major Antioxidant Compounds of Some Wild Herbs of the <i>Asteraceae</i>Family

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Food and Nutrition Sciences 2011年第3期2卷 181-192页

作者： Didier Fraisse Catherine Felgines Odile Texier jean-louis Lamaison 不详

The polyphenolic composition and antioxidant activity of the aerial parts of 18 medicinal or food plants of the As- teraceae family were studied. Five main caffeoyl derivatives were determined individually by HPLC and compared with levels determined by colorimetry for total dihydroxycinnamic derivatives and total phenolics. The aim of this study was to assess the contribution of these constituents to the antioxidant activity of the herbs determined by DPPH radical scavenging tests. Significant correlations were found between total phenolic (R2 = 0.8904), total dihydroxycinnamic derivative (R2 = 0.8529) and total caffeoyl derivative (R2 = 0.7172) concentrations and the DPPH-scavenging ability of all herbs. The antioxidant activity of the main constituents, including chicoric acid (EC50 = 8.24 μmol/l) or 3,5- dicaffeoylquinic acid (EC50 = 7.62 μmol/l), was very high compared to vitamin C (EC50 = 15.66 μmol/l). Thus, for each species, antioxidant activity mainly involves the major caffeoyl derivatives. The contribution to antioxidant activity were assessed as 48.92% for 3,5-dicaffeoylquinic acid in Tanacetum parthenium (30.08 g/kg), and 68.96% for chicoric acid in Taraxacum officinale (34.08 g/kg). The main caffeoyl derivatives among polyphenols can be considered as the major antioxidant compounds of the studied Asteraceae herbs.

关键词： Plants Asteraceae Caffeoyl Derivatives Antioxidant

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Forecast for the Cameroon’s Residential Electricity Demand Based on the Multilinear Regression Model

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Energy and Power Engineering 2020年第5期12卷 182-192页

作者： Serge Guefano jean Gaston Tamba louis Monkam Beguide Bonoma Institute of Technology University of Douala Douala Cameroon Higher Teacher Training College University of Yaoundé I Yaoundé Cameroon

The electricity needs of populations in Cameroon are increasing and are still very inadequate. Companies, public buildings and households are facing frequent blackout which constrain development and social well-being. Therefore, the present work tried to forecast the electricity demand in the residential sector in Cameroon, in order to contribute significantly to the mastery of electricity consumption and highlight decision-makers in this sector. Six macroeconomics parameters covering the period 1994-2014 are used for these issues. Stationarity tests within gross domestic product, gross domestic product per capita, electricity consumption, population and numbers of subscribers and households respectively;reveal that all the series are I(1). Thus, the VAR (Vector Autoregressive) model has been retained to forecast the electricity demand until 2020. The cusum test and the cusum of squared test attest the stability of that model with a margin of error of 0.02%. Previsions are then more reliable and show that the electric request will skip from 1721 GWh in 2014 to more than 2481 GWh in 2020 approximatively, following a growing yearly rate of 5.36%. In order to reach its emergence, Cameroon ought to speed up its production in the domain of hydroelectric and thermal grid in order to meet the requirements in electric power in short and long term.

关键词： Modeling of the Electricity Demand Forecast Residential Sector VAR Model Cameroon

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Modelling of the Quantum Transport in Strained Si/SiGe/Si Superlattices Based P-i-n Infrared Photodetectors for 1.3 - 1.55 μm Optical Communication

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Modeling and Numerical Simulation of Material Science 2014年第1期4卷 37-52页

作者： Noureddine Sfina Naima Yahyaoui Moncef Said jean-louis Lazzari Department of Physics Faculty of Sciences of Monastir Laboratory of Condensed Matter and Nanosciences (LMCN) Monastir Tunisia Interdisciplinary Nanoscience Centre of Marseille (CINaM) Aix-Marseille University Marseille France

In this paper, a p-i-n heterojunction based on strain-compensated Si/Si1-xGex/Si multiple quantum wells on relaxed Si1-yGey is proposed for photodetection applications. The Si1-yGey/Si/Si1-xGex/Si/Si1-yGey stack consists in a W-like potential profile strain-compensated in the two low absorption windows of silica fibers infrared (IR) photodetectors. These computations have been used for the study of p-i-n infrared photodetectors operating at room temperature (RT) in the range 1.3 - 1.55 μm. The electron transport in the Si/Si1-xGex/Si multi-quantum wells-based p-i-n structure was analyzed and numerically simulated taking into account tunneling process and thermally activated transfer through the barriers mainly. These processes were modeled with a system of Schrodinger and kinetic equations self-consistently resolved with the Poisson equation. Temperature dependence of zero-bias resistance area product (RoA) and bias-dependent dynamic resistance of the diode have been analyzed in details to investigate the contribution of dark current mechanisms which reduce the electrical performances of the diode.

关键词： Strained SiGe/Si Quantum Wells Band Structure Device Engineering P-i-n Infrared Photodetectors

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Direct Determination of Radionuclides in the Body Optimisation of Measurements Parameters and Results Analysis

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World Journal of Nuclear Science and Technology 2011年第3期1卷 87-110页

作者： jean louis Genicot Telma Fonseca Gary Kramer André Wambersie 不详

Whole body counting (WBC) benefits from new types of detectors and methodologies. It has found applications in areas such as in medicine, protection of workers and of population. The design of a WBC facility should be tailored to the type of application. Monte Carlo calculations help to improve the reliability of the calibration of a facility, particularly for non-standard measurements (child, etc.), help in optimizing shielding of counting rooms, preventing large systematic errors and lowering detection limits. In vivo counting may be used to evaluate the distribution of radionuclides in organs for metabolic studies with multiple detectors or with a scan of the body. Reduction of detection levels by background reduction is limited. Improved sensitivity can be obtained by adapting the detector type and size to the measured photon energy. The benefit of comparison exercises and training courses are demonstrated. Further improvements in accuracy can be expected from cooperative works with other techniques: indirect methods (urines and faeces) and passive detectors placed correctly on the body can in the case of high levels of contamination can be used to improve the burden assessment.

关键词： WBC in vivo Counting Internal Dosimetry Internal Contamination

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The catalytic properties of DNA G‐quadruplexes rely on their structural integrity

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Chinese Journal of Catalysis 2021年第7期42卷 1102-1107页

作者： Jielin Chen Mingpan Cheng Jiawei Wang Dehui Qiu David Monchaud jean‐louis Mergny Huangxian Ju Jun Zhou State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023JiangsuChina Institut de Chimie Moléculaire Universitéde Bourgogne(ICMUB)CNRS UMR6302UBFC Dijon 21000France Laboratoire d’Optique et Biosciences Ecole PolytechniqueCNRSINSERMInstitut Polytechnique de Paris91128 PalaiseauFrance

The influence of the G‐quartet structural integrity on the catalytic activity of the G‐quadruplex(G4)was investigated by comparing the G4‐DNAzyme performances of a series of G4s with a G‐vacancy site and a G‐triplex(G‐tri).The results presented herein not only confirm that the structural integrity of the 3'‐end G‐quartet is necessary for G4s to be catalytically competent but also show how to remediate G‐vacancy‐mediated catalytic activity losses via the addition of guanine surrogates in an approach referred to as G‐vacancy complementation strategy that is applicable to parallel G4s ***,this study demonstrates that the terminal G‐quartet could act as a proximal coordinating group and cooperate with the flanking nucleotide to activate the hemin cofactor.

关键词： G‐quadruplex G‐quadruplex DNAzyme G‐vacancy G‐quartet integrity Guanine surrogate

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