Identifying sex-specific differences in the carotid revascularisation literature:findings from a scoping review
作者机构：Department of MedicineDivision of Neurology and Ottawa Hospital Research InstituteUniversity of OttawaOttawaOntarioCanada Epidemiology ProgramOttawa Hospital Research InstituteOttawaOntarioCanada Stroke Prevention ClinicOttawa HospitalOttawaOntarioCanada Bioethics ProgramUC Davis Department of MedicineSacramentoCaliforniaUSA Universite Paris Descartes Faculte de Medecine Site CochinParislle-de-FranceFrance Service de NeurologieHôital Sainte-AnneParisFrance The University of Alabama at Birmingham School of MedicineBirminghamAlabamaUSA School of Public HealthUniversity of Alabama at BirminghamBirminghamAlabamaUSA 不详
出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)
年 卷 期：2021年第6卷第3期
页 面：496-499,I0085-I0096页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：the Heart and Stroke Foundation of Canada (Seed Catalyst Grant for Women's Health no award/grant number) the Department of Medicine, University of Ottawa
摘 要：Objective No systematic review of the literature has dedicated itself to looking at the management of symptomatic carotid stenosis in female *** this scoping review,we aimed to identify all randomised controlled trials(RCTs)that reported sex-specific outcomes for patients who underwent carotid revascularisation,and determine whether sufficient information is reported within these studies to assess short-term and long-term outcomes in female ***,setting and participants We systematically searched Medline,Embase,Pubmed and Cochrane libraries for RCTs published between 1991 and 2020 that included female patients and compared either endarterectomy with stenting,or any revascularisation(endarterectomy or stenting)with medical therapy in patients with symptomatic high-grade(50%)carotid *** From 1537 references examined,27 eligible studies were ***-specific outcomes were reported in 13 *** patient characteristics of enrolled female patients were reported in 2 of those 13 *** outcomes reported included stroke and death,however,there was significant heterogeneity in the reporting of both periprocedural and long-term ***-specific differences relating to the degree of stenosis and time from index event to treatment are largely limited to studies comparing endarterectomy to medical *** events were not reported by *** Only half of the previously published RCTs and systematic reviews report sex-specific *** analyses on the results of carotid artery intervention for female patients with symptomatic stenosis are limited.
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