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Alphabet strategy for diabetes care:A checklist approach in the time of COVId-19 and beyond

World Journal of diabetes 2021年第4期12卷 407-419页

作者： Rajeev Upreti james d lee Satyan Kotecha Vinod Patel department of Endocrinology George Eliot HospitalNuneaton CV107DJUnited Kingdom

Chronic disease management requires achievement of critical individualised targets to mitigate again long-term morbidity and premature mortality associated with diabetes *** responsibility for this lies with both the patient and health care *** plans have been introduced in many healthcare settings to provide a patient-centred approach that is both evidence-based to deliver positive clinical outcomes and allow individualised *** Alphabet strategy(AS) for diabetes is based around such a care plan and has been evidenced to deliver high clinical standards in both well-resourced and underresourced *** patient educational resources include special care plans for those people with diabetes undertaking fasting during Ramadan,Preconception Care, Prevention and Remission of *** Strategy and Care Plan has facilitated evidence-based,cost-efficient multifactorial intervention with an improvement in the National diabetes Audit targets for blood pressure,cholesterol levels and glycated *** of these attainments were of the standard seen in intensively treated cohorts of key randomized controlled trials in diabetes care such as the Steno-2 and United Kingdom Prospective diabetes *** is despite working in a relatively under-resourced service within the United Kingdom National Health *** AS for diabetes care is a useful tool to consider for planning care, education of people with diabetes and healthcare *** the time of the coronavirus disease 2019 pandemic the risk factors for the increased mortality observed have to be addressed *** AS has the potential to help with this aspiration.

关键词： Alphabet strategy COVId-19 Care planning Chronic disease diabetes care Multifactorial interventions Patient care

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Reply to comment by durkin et *** “Using a modern analogue to interpret depositional position in ancient fluvial-tidal channels:Example from the McMurray Formation,Canada” by *** Croix,***,and ***

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Geoscience Frontiers 2020年第3期11卷 1087-1092页

作者： Andrew d.la Croix Shahin E.dashtgard james A.MacEachern School of Science University of WaikatoHamilton3240New Zealand Applied Research in Ichnology and Sedimentology(ARISE)Group Department of Earth SciencesSimon Fraser UniversityBurnabyBCV5A 1S6Canada

*** We are pleased to have the opportunity to discuss our paper (la Croix et al.,2019) with durkin et al.(2020).Their critique demonstrates the wide interest in the McMurray Formation held by both academic and industry geoscientists,especially given the economic importance of the stratigraphic ***,it highlights the various working interpretations for the unit’s paleoenvironmental setting and stratigraphic architecture;two highly contested scientific *** et al.

关键词： al. Canada fluvial

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A simple,azulene-based colorimetric probe for the detection of nitrite in water

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Frontiers of Chemical Science and Engineering 2020年第1期14卷 90-96,F0004页

作者： lloyd C.Murfin Carlos M.lopez-Alled Adam C.Sedgwick Jannis Wenk Tony d.james Simon E.lewis department of Chemistry University of BathBath BA27AYUK Centre for Sustainable Chemical Technologies University of BathBath BA27AYUK department of Chemical Engineering and Water Innovation and Research Centre(WIRC@Bath) University of BathBath BA27AYUK

We describe the synthesis and evaluation of an azulene-based chemodosimeter for *** probe was found to undergo two distinct color changes upon introduction of aqueous nitrite ion.A near-instant formation of a grey color provides a qualitative indication of the presence of nitrite,followed by the formation of a deep-yellow/orange color,the endpoint from which quantitative data can be *** azulene probe exhibits 1:1 stoichiometry of reaction with nitrite in water,and is selective for nitrite over other *** azulene probe was applied to determine nitrite content in cured meat,and compared with the British Standard testing procedure(Griess test).The value obtained from the azulene-based probe agreed closely with the standard *** procedure only requires the preparation of one standard solution,instead of the three required for the standard Griess test.

关键词： azulene nitrite diazoquinone

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Nanomineralogy of evaporative precipitation of efflorescent compounds from coal mine drainage

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Geoscience Frontiers 2021年第6期12卷 404-410页

作者： luis F.O.Silva diana Pinto Guilherme l.dotto james C.Hower department of Civil and Environmental.Universidad de la Costa CUCCalle 58#55–66BarranquillaAtlanticoColombia Universidade Federal de Santa Maria–UFSM 1000Roraima Avenue97105–900Santa MariaRSBrazil University of Kentucky Department of Earth&Environmental SciencesLexingtonKY40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY40511USA

Efflorescent nanophases(NPs) are found as a transitory accumulation of potentially hazardous elements(PHEs),particularly in tropical climates. The central objective of this study was to investigate the distribution of PHEs with NPs through the evaporative formation structures(EFS) of enormously PHEs-rich coal-mine drainages(CMd). The EFS were studied in natural coal mine drainage for five months in order to determine their geochemical and ecological structures and to assess their position in the reduction of PHEs in nature. The largest coal-fired power plant in South America, located in south Brazil, is used as an example of such a problem. In this work, a novel methodology for the analysis of PHEs in CMd precipitates is proposed for this affected coal *** analytical method, combining X-Ray diffraction(XRd) and advanced electron microscopies, shows the importance of nanomineralogy in understanding different circumstances of coal contamination. Several ultrafinenanoparticles(UNPs) were identified in the sampled soils and river sediments together with the PHEs. A decrease in PHEs was identified in association with UNPs. However, further investigations are required with regard to the mobility of PHEs in water, atmosphere, soils, and sediments. The EPS was thoroughly studied, acquiring suitable understanding with investigational facts for Ca and Fe-sulphates, pickeringite, and several amorphous phases.

关键词： Coal mine drainage Evaporative precipitation Sediments Water and soil pollution

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Selective androgen receptor modulators for the treatment of late onset male hypogonadism

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Asian Journal of Andrology 2014年第2期16卷 256-261,I0009页

作者： Christopher C Coss Amanda Jones Michael l Hancock Mitchell S Steiner james T dalton GTx Inc. Memphis Tennessee USA.

Several testosterone preparations are used in the treatment of hypogonadism in the ageing male. These therapies differ in their convenience, flexibility, regional availability and expense but share their pharmacokinetic basis of approval and dearth of long-term safety data. The brevity and relatively reduced cost of pharmacokinetic based registration trials provides little commercial incentive to develop improved novel therapies for the treatment of late onset male hypogonadism. Selective androgen receptor modulators （SARMs） have been shown to provide anabolic benefit in the absence of androgenic effects on prostate, hair and skin. Current clinical development for SARMs is focused on acute muscle wasting conditions with defined clinical endpoints of physical function and lean body mass. Similar regulatory clarity concerning clinical deficits in men with hypogonadism is required before the beneficial pharmacology and desirable pharmacokinetics of SARMs can be employed in the treatment of late onset male hypogonadism.

关键词： hypogonadism late onset hypogonadism selective androgen receptor modulators testosterone

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Investigation of the preparation methodologies of Pd-Cu single atom alloy catalysts for selective hydrogenation of acetylene

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Frontiers of Chemical Science and Engineering 2015年第4期9卷 442-449页

作者： Xinxiang Cao Arash Mirjalili james Wheeler Wentao Xie Ben W.-l. Jang department of Chemistry Texas A&M University-Commerce Commerce TX 75429-3011 USA

Galvanic replacement, co-impregnation and sequential impregnation have been employed to prepare Pd-Cu bimetallic catalysts with less than 1 wt-% Cu and ca. 0.03 wt-% Pd for selective hydrogenation of acetylene in excess ethylene. High angle annular dark field-scanning transmission electron microscopy （HAAdF-STEM） and H2 chemisorption results confirmed that Pd-Cu singleatom alloy structures were constructed in all three bimetallic catalysts. Catalytic tests indicated that when the conversion of acetylene was above 99%, the selectivity of ethylene of these three single atom alloy catalysts was still more than 73%. Furthermore, the single atom alloy catalyst prepared by sequential incipient wetness impregnation was found to have the best stability among the three procedures used.

关键词： palladium-copper bimetallic catalyst singleatom alloy acetylene hydrogenation HAAdF-STEM H2pulse chemisorption

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Sugarcane press mud modification of expansive soil stabilized at optimum lime content:Strength,mineralogy and microstructural investigation

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第2期12卷 395-402页

作者： Jijo james SSN College of Engineering Chennai603110India

This study attempted to investigate the potential of sugarcane press mud(PM) as a secondary additive in conjunction with lime for the stabilization of an expansive *** physico-mechanical properties of an expansive soil,such as plasticity,shrink-swell behavior,unconfined compressive strength(UCS),mineralogical and microstructural characteristics were *** expansive soil was stabilized at its optimum lime content(7%) for producing maximum strength,and was modified with four different quantities of PM in small dosages(0.25%-2%).Cylindrical soil samples,38 mm in diameter and 76 mm in height,were cast and cured for varying periods to evaluate the strength of the amended *** spent samples after strength tests were further used for determination of other *** test results revealed that PM modification led to a substantial improvement in 7-d strength and noticeable increase in 28-d strength of the lime-stabilized soil(lSS).The addition of PM does not cause any detrimental changes to the shrink-swell properties as well as plasticity nature of the stabilized soil,despite being a material of organic *** investigation revealed that the formation of calcium silicate hydrate(CSH) minerals,similar to that of pure lime stabilization with only the type of mineral varying due to the modification of PM addition,does not significantly alter the microstructure of the lSS except for superficial changes being noticed.

关键词： Expansive soil lime stabilization Press mud(PM) Strength Shrink-swell Mineralogy Microstructure

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Examining the use of narrative constructs in data videos

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Visual Informatics 2020年第1期4卷 8-22页

作者： Ruochen Cao Subrata dey Andrew Cunningham james Walsh Ross T.smith Joanne E.Zucco Bruce H.Thomas The School of Information Technology and Mathematical Science University of South AustraliaAustralia department of Media University of AdelaideAustralia

data videos are a highly impactful method of communication and are becoming a prevalent medium for communicating *** the majority of current research focuses on the cinematic aspects of data videos,very little is known about the narrative methodologies *** paper presents our insights derived from an initial exploration of this *** present a taxonomy based on the analysis of 70 existing data videos examining their narrative and visual *** propose that our taxonomy can be used to explain the characteristics or design of data *** this taxonomy,we present our observations,including the trend of popular technologies applied in current data videos,the under-utilization of promising methods,and highlight research opportunities in the field.

关键词： Narrative visualization data videos Taxonomy Narrative approaches

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来自昆虫的灵感（英文）

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山西农业大学学报（自然科学版） 2018年第1期38卷 1-5页

作者： james Ridsdill-smith 西澳大学生物科学学院澳大利亚珀斯澳大利亚联邦科工组织土地和水研究部澳大利亚珀斯

昆虫在约4亿多年的进化过程中,成功地发展了多种多样的适应与生存绝技。创新科技的运用使科学家们能够解析不同昆虫新奇的化合物和特性,并将其用于工业和医学领域的仿生学研究。如受昆虫行走启发设计的机器人,根据昆虫色彩创造的军事伪... 详细信息

昆虫在约4亿多年的进化过程中,成功地发展了多种多样的适应与生存绝技。创新科技的运用使科学家们能够解析不同昆虫新奇的化合物和特性,并将其用于工业和医学领域的仿生学研究。如受昆虫行走启发设计的机器人,根据昆虫色彩创造的军事伪装术,通过模拟昆虫飞行制造的微型探测器等,处处体现了来自昆虫的灵感。

关键词：昆虫仿生学进化

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Sleep,immunity and inflammation in gastrointestinal disorders

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World Journal of Gastroenterology 2013年第48期19卷 9231-9239页

作者： Tauseef Ali james Choe Ahmed Awab Theodore l Wagener William C Orr Inflammatory Bowel disease Center University of Oklahoma Health Sciences Center Oklahoma City OK 73104 United States department of Medicine University of Oklahoma Health Science Center Oklahoma City OK 73104 United States department of Medicine Section of Pulmonary and Critical Care Oklahoma City OK 73104 United States department of Pediatrics University of Oklahoma Health Sciences Center Oklahoma City OK 73104 United States lynn Health Science Institute Oklahoma City OK 73112 United States

Sleep disorders have become a global issue,and discovering their causes and consequences are the focus of many research *** estimated 70 million Americans suffer from some form of sleep *** sleep disorders have been shown to cause neurocognitive impairment such as decreased cognitive ability,slower response times and performance *** research suggests that individuals with sleep abnormalities are also at greater risk of serious adverse health,economic consequences,and most importantly increased all-cause *** research studies support the associations among sleep,immune function and ***,we review the current research linking sleep,immune function,and gastrointestinal diseases and discuss the interdependent relationship between sleep and these gastrointestinal *** physiologic processes including immune system and inflammatory cytokines help regulate the *** inflammatory cytokines such as tumor necrosis factor,interleukin-1(Il-1),and Il-6 have been shown to be a significant contributor of sleep *** the other hand,sleep disturbances such as sleep deprivation have been shown to up regulate these inflammatory *** in these cytokine levels have been demonstrated in certain gastrointestinal diseases such as inflammatory bowel disease,gastro-esophageal reflux,liver disorders and colorectal *** turn,abnormal sleep brought on by these diseases is shown to contribute to the severity of these same gastrointestinal *** of these relationships will allow gastroenterologists a great opportunity to enhance the care of their patients.

关键词： Sleep Immune function Immunity Irritable bowel syndrome Inflammatory bowel disease Gastroesophageal reflux disease liver disorders Colon cancer Circadian rhythm

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