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Effect of ultrasound on reverse leakage current of silicon Schottky barrier structure

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Journal of Semiconductors 2016年第12期37卷 5-11页

作者： O.Ya Olikh K.V.Voitenko R.m.Burbelo ja m.Olikh Faculty of Physics Taras Shevchenko National University of Kyiv V Lashkaryov Institute of Semiconductor Physics National Academy of Sciences of Ukraine

The influence of ultrasonic loading on reverse current-voltage characteristics of mo/n-n＋-Si structures has been investigated. The research of leakage current variation has been carried out for various ultrasonic wave frequencies （4.1 and 8.4 mHz）, intensities （up to 0.8 W/cm2） and loading temperatures （130-330 K）. The observed reversible acoustically induced increase in reverse currents was as large as 60%. It has been found that dominant charge transfer mechanisms are the thermionic emission （at high temperature） and the phonon-assisted tunneling （at low temperature）. The ultrasound loading affects both processes due to the decrease of Schottky barrier height and binding energy of the electron on the trap.

关键词： Schottky contact leakage current ultrasound influence

Growth characteristics and pathogenic consequences of predominant entomopathogenic Yukon soil fungi mortierella alpina and Penicillium expansum,and effectiveness of met52®,against larvae of the winter tick,Dermacentor albipictus

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Studies in Fungi 2019年第1期4卷 101-110页

作者： Yoder ja Krieger m Oakley m Trotter J Schmelzer P Niksic A Rodell Bm Klever LA Department of Biology Wittenberg UniversitySpringfieldOH45501USA Champagne and Aishihik First Nations Haines JunctionYTY0B 1L0CAN Oakley Veterinary Services HainesAK99827USA

Water activity-temperature relationships are reported for Yukon soil-isolated strains of mortierella alpina and Penicillium expansum that are natural enemies to larvae(infestation stage)of the winter tick Dermacentor *** fungal strains are psychrotrophs,characterized by low thermal growth ranges,consistent with their occurrence in Yukon *** contrast to ***,*** is more temperature sensitive,has a higher requirement,and is more virulent to tick *** and Biological Control Officers should note that for tick population control these *** and *** strains grow and sporulate well under moderate temperature and humid *** experiments used met52®Bioinsecticide as a positive control,and this is the first study that demonstrates the effectiveness of this commercial product against winter tick larvae.

关键词： Alaska biological control Canada elk tick horse tick moose tick temperature water activity

Coastal landscape evolution tracked from late Holocene wave-cut benches in the Sinan Archipelago,Southwest Korea

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Geoscience Frontiers 2020年第1期11卷 293-301页

作者： Sung-ja Choi Bokchul Kim Yong Sik Gihm Sanghoon Kwon Geology Division Korea Institute of Geoscience and Mineral ResourcesDaejeon34132Republic of Korea Department of Earth System Sciences Yonsei UniversitySeoul03722Republic of Korea School of Earth Sciences The Ohio State UniversityColumbusOH43210USA

Glacio-isostatic adjustment(GIA)and tectonic activity are important factors in the formation of marine *** Holocene wave-cut benches in the eastern part of the West Sea of Korea,also called the Yellow Sea,can be divided into two steps:531 cm above sea level(ASL)for the upper bench(T2)and 464-481 cm ASL for the lower bench(T1).Sediments on the benches a re classified into four units,and are interpreted to be beach deposits acco rding to gravel shape,textu re,and seaward *** ove rlying sediment indicates that T2 was formed at approximately 530 cm ASL before 2900 yr BP,and T1 at approximately 460-480 cm ASL before 1520 yr *** Holocene(4000-2000 yr BP)relative sea level(RSL)curves based on GIA models are inconsistent with the wave-cut bench *** T1 and T2 benches to the RSL curves of the West Sea,the upper and the lower benches were uplifted by approximately 5-8 m and 4-7 m,*** the area is several hundred kilometers away from plate boundaries,the high frequency of earthquakes in the West Sea may have induced the uplift of wave-cut benches during the last 2000 *** indicate that the west coast of the Korean Peninsula(KP)should no longer be considered an area of subsidence,but be assigned to a regime of uplift during the late Holocene.

关键词： West Sea of Korea Yellow Sea Late Holocene Wave-cut benches Beach sediment Uplift Tectonics

Developments in diagnosis and treatment of paediatric septic arthritis

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World Journal of Orthopedics 2022年第2期13卷 122-130页

作者： Cornelia m Donders Anne J Spaans Herbert van Wering Christiaan ja van Bergen Department of Orthopaedic Surgery Meander Medical CentreAmersfoort 3813 TZNetherlands Department of Orthopaedic Surgery Sint MaartenskliniekNijmegen 6574 NANetherlands Department of Paediatrics Amphia HospitalBreda 4818 CKNetherlands Department of Orthopedic Surgery Amphia HospitalBreda 4818 CKNetherlands

Acute septic arthritis in children is an orthopaedic emergency.A delay in diagnosis and inappropriate treatment can result in devastating damage to the joint with lifelong disability as a *** clinical presentation can be a diagnostic challenge,especially in young children.A recent systematic review showed that joint tenderness and fever are important signals of septic *** is helpful in detecting the presence of a joint *** radiographs may show bone changes but magnetic resonance imaging is the most reliable imaging study for detecting concomitant *** diagnosis of acute septic arthritis is highly suggestive when pus is aspirated from the joint,in case of a positive culture or a positive gram stain of the joint fluid,or if there is a white blood-cell count in the joint fluid of more than 50000/*** aureus is the most commonly cultured *** systematic reviews have identified the most effective drainage techniques,including needle aspiration,arthroscopy and arthrotomy,depending on the affected *** the drainage procedure it is important to monitor the clinical and laboratory *** drainage procedures may be necessary in select cases.

关键词： Septic arthritis Paediatric Children Analysis Treatment Drainage

Decadal Changes in Climatological Intraseasonal Fluctuation of Subseasonal Evolution of Summer Precipitation over the Korean Peninsula in the mid-1990s

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Advances in Atmospheric Sciences 2011年第3期28卷 591-600页

作者： Wonmoo KIm Jong-Ghap JHUN Kyung-ja HA masahide KImOTO School of Earth and Environmental Sciences/Research Institute of Oceanography Seoul National University151-742Korea Divison of Earth Environmental System Pusan National University609-735Korea Atmosphere and Ocean Research Institute University of Tokyo277-8564Japan

Decadal changes in the subseasonal evolution and the phase-locked climatological intraseasonal fluctuation of summertime rainfall over the Korean Peninsula before and after the mid-1990s are *** activity and the migration speed of the monsoon rain band over the East Asian region are altered in the recent decade,resulting in the drier conditions in late spring and the earlier onset of *** early August when a climatological monsoon break was clear in the earlier decade,the precipitation has increased dramatically with a meridional *** response to the enhanced convection over the South China Sea and southeastern China provides a favorable condition for more precipitation in early August through the changes in moisture transport and tropical cyclone passage.

关键词： decadal change intraseasonal fluctuation East Asian summer monsoon

Entomopathogenic fungi isolated from Yukon soil against unfed larvae of the winter tick,Dermacentor albipictus

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Studies in Fungi 2019年第1期4卷 123-134页

作者： Dobrotka CJ Krieger m Oakley m Trotter J Rodell Bm Stein KL Klever LA Fisher KA Yoder ja Department of Biology Wittenberg UniversitySpringfieldOH45501USA Champagne and Aishihik First Nations Haines JunctionYTY0B 1L0CAN Oakley Veterinary Services HainesAK99827USA

Fungal composition of Yukon soil samples consisted of 29 soil saprobes common to acidified forest,subarctic *** of the fungi identified are psychrotrophs,capable of growth at both 4℃ and 20℃.Of these,a total of 17 fungi were found to be entomopathogenic by winter tick(Dermacentor albipictus)larval bioassays:Aspergillus flavus,Beauveria,namely ***,mucor,Paecilomyces yielded>~70%larval mortality and the remainder,mostly mortierella and Penicillium,averaged~40%larval *** where elk(Cervus elaphus canadensis)are observed had an overall greater quantity,and diversity of entomopathogenic soil fungi than sites where elk are not *** diversity of fungi at elk-inhabited sites is likely a product of warmer soil microclimate(hillsides where elk are seen,lose snow earlier than other areas),animal presence,and increased nutrient *** conclude that Yukon soils contain fungi that naturally regulate populations of *** fungi are archived at the Wittenberg University Fungus Collection,Springfield,OH,USA.

关键词： Biological control mycoflora moose tick elk tick horse tick Canada Alaska

A Short Amino-Terminal Part of Arabidopsis Phytochrome A Induces Constitutive Photomorphogenic Response

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molecular Plant 2012年第3期5卷 629-641页

作者： Andra＇s Viczia＇n E＇va Ada＇m Iris Wolf ja＇nos Bindics Stefan Kircher marc Heijde Roman Ulm Eberhard Scha＇fer Ferenc Nagy Institute of Plant Biology Biological Research Centre of the Hungarian Academy of Sciences Temesva＇ri krt. 62. H-6726 Szeged Hungary Biologie II/Institut for Botanik University of Freiburg Freiburg Dermany Department of Botany and Plant Biology University of Geneva Geneva Switzerland Centre for Biological Signalling Studies （BIOSS） University of Freiburg Freiburg Germany School of Biological Sciences University of Edinburgh Edinburgh UK

Phytochrome A （phyA） is the dominant photoreceptor of far-red light sensing in Arabidopsis thaliana, phyA accumulates at high levels in the cytoplasm of etiolated seedlings, and light-induced phyA signaling is mediated by a com- plex regulatory network. This includes light- and FHY1/FHL protein-dependent translocation of native phyA into the nucleus in vivo. It has also been shown that a short N-terminal fragment of phyA （PHYA406） is sufficient to phenocopy this highly regulated cellular process in vitro. To test the biological activity of this N-terminal fragment of phyA in planta, we produced transgenic phyA-201 plants expressing the PHYA406-YFP （YELLOW FLUORESCENT PROTEIN）-DD, PHYA406- YFP-DD-NLS （nuclear localization signal）, and PHYA406-YFP-DD-NES （nuclear export signal） fusion proteins. Here, we report that PHYA406-YFP-DD is imported into the nucleus and this process is partially light-dependent whereas PHYA406-YFP-DD-NLS and PHYA406-YFP-DD-NES display the expected constitutive localization patterns. Our results show that these truncated phyA proteins are light-stable, they trigger a constitutive photomorphogenic-like response when localized in the nuclei, and neither of them induces proper phyA signaling. We demonstrate that in vitro and in vivo PHYA406 Pfr and Pr bind COP1, a general repressor of photomorphogenesis, and co-localize with it in nuclear bodies. Thus, we conclude that, in planta, the truncated PHYA406 proteins inactivate COP1 in the nuclei in a light-independent fashion.

关键词： Arabidopsis cop phenotype phytochrome A COP1

Drugging SUmOylation for neuroprotection and oncotherapy

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Neural Regeneration Research 2018年第3期13卷 415-416页

作者： Joshua D. Bernstock Daniel G. Ye Yang-ja Lee Florian Gessler Gregory K. Friedman Wei Zheng John m. Hallenbeck Stroke Branch National Institute of Neurological Disorders and Stroke National institutes of Health (NINDS/NIH) Bethesda MD USA Department of Clinical Neurosciences - Division of Stem Cell Neurobiology Wellcome Trust-Medical Research Council Stem Cell Institute and NIHR Biomedical Research Centre University of Cambridge UK Department of Pediatrics Division of Pediatric Hematology and Oncology University of Alabama at Birmingham Birmingham AL USA National Center for Advancing Translational Sciences National Institutes of Health (NCATS/NIH) Bethesda MD USA

Recently there have been exciting research advances in neuroprotective therapies for ischemic stroke. In the past, the search for neu- roprotective agents has been fraught with failure at the clinical trials stage due to numerous factors, including subject heterogeneity and improper therapeutic windows （Tymianski, 2017）. moreover, it is becoming clearer that the complex and evolving pathobiology of stroke requires multimodal therapeutic approaches capable of modulating the numerous axes that contribute to ischemia/reperfusion damage, rather than targeting a single axis （Bernstock et al., 2018a）. With the success of recent endovascular thrombectomy （EVT） trials, it has been suggested that clinical trials of EVT with adjunct neuroprotection can overcome past difficulties and maximize the effect size by using imaging to reduce patient heterogeneity （i. e., selecting those with large vessel occlusions, small ischemic cores, and good collateral circulation）, restoring perfusion using better EVT devices, and enrolling patients in the correct therapeutic window （i.e., when they still have salvageable brain tissue）（Tymianski, 2017）. Considering the opportunity that this represents for new, better clinical trials of neuroprotective agents, the search is on for high-potential compounds that may be investigated in these future studies.

关键词： Drugging SUmOylation for neuroprotection and oncotherapy OGD

Acute liver failure is frequent during heat stroke

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World Journal of Gastroenterology 2008年第1期14卷 158-159页

作者： Jm Garcin ja Bronstein S Cremades P Courbin F Cointet Clinique médicale hpital d'instruction des armées Bégin F 94163 Saint Mandé France Service de pathologie digestive hpital d'instruction des armées Clermont Tonnerre F 29200 Brest France

Acute liver failure （ALF） is relatively frequent during heat stroke （HS）. This risk must be emphasized, because its inddence is higher than is usually thought. In a recent study by Weigand et al, two cases were reported in which liver failure was the leading symptom. We have confirmed their conclusion in a study of 25 cases of HS with ALF, compared with 25 other cases without ALE moreover, we observed that hypophosphatemia on admission could predict occurrence of ALF during HS. As for clinical and other biological parameters, phosphatemia should be monitored for at least 3 d in all cases of HS, even when it is thought to be mild.

关键词： Heat stroke, Hypophosphatemia Liver failure