检索结果-南通市图书馆

BIOCELL 2022年第9期46卷 2009-2013页

作者： juliana soares DOUGLAS G.FREITAS PEDRO S.LOURENÇO JEFTE FARIAS BRUNO PONTES Centro Nacional de Biologia Estrutural e Bioimagem-CENABIO Universidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação em Ciências Biológicas Biofísica Instituto de Biofísica Carlos Chagas FilhoUniversidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação Multidisciplinar em Física Aplicada Instituto de FísicaUniversidade Federal do Rio de JaneiroRio de Janeiro21941-972Brazil Instituto de Ciências Biomédicas Universidade Federal do Rio de JaneiroRio de Janeiro21941-902Brazil Programa de Pós-graduação em Biotecnologia Instituto de Ciências BiológicasUniversidade Federal do AmazonasManaus69067-005Brazil

Mammalian cell surfaces consist of the plasma membrane supported by an underneath cortical ***,these structures can control not only the shape of cells but also a series of cellular functions ranging from migration and division to exocytosis,endocytosis and ***,the cell surface is capable of exerting and reacting to mechanical *** viscoelastic properties,especially membrane tension and bending modulus,are fundamental parameters involved in these *** viewpoint summarizes our current knowledge on how to measure the viscoelastic properties of cell surfaces employing optical tweezers-based tether assays,paving the way for a better understanding of how cells react to external mechanical forces,with a glance on their remodeling dynamics and possible consequences on downstream cellular processes.

关键词： Cell surface architecture Actin cortex Membrane-cytoskeleton complex Optical tweezers Tether extraction

Amino acid digestibility in low-fat distillers dried grains with solubles fed to growing pigs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2014年第4期5卷 414-420页

作者： Shelby Marie Curry Diego Mario David Labadan Navarro Ferdinando Nielsen Almeida juliana Abranches soares Almeida Hans Henrik Stein Department of Animal Sciences University of Illinois

The objective of this experiment was to determine the standardized ileal digestibility（SID） of amino acids（AA） in 3sources of distillers dried grains with solubles（DDGS） with different concentrations of *** growing barrows（initial body weight：76.1 ± 6.2 kg） were randomly allotted to a replicated 6×4 Youden square design with 6 diets and 4 *** fat content of the 3 sources of DDGS were 11.5,7.5,and 6.9%*** contained 60%DDGS and fat concentration of the diets were 7.5,52,and 5.2%,*** additional diets containing the 2sources of DDGS with 75 and 6.9%fat were also formulated,and corn oil was added to these diets to increase the concentration of fat in the diets to levels that were calculated to be similar to the diet containing conventional DDGS with 11.5%fat.A N-free diet was also formulated to calculate endogenous losses of crude protein（CP） and AA from the *** were fed experimental diets during four 7-d *** first 5 d of each period were an adaptation period and ileal digesta were collected on d 6 and 7 of each *** apparent ileal digestibililty（AID） and SID of CP and all indispensable AA,except AID Pro and SID of Trp,were greater（P 〈 0.01） in conventional DDGS than in the 2 sources of DDGS with reduced *** oil to the diets containing the 2 sources of DDGS with reduced fat did not consistently increase SID of *** conclusion,conventional DDGS has greater SID values for most AA compared with DDGS that contains less fat and inclusion of additional oil to diets containing low-fat DDGS does not increase AID or SID of *** lower AA digestibility in low-fat DDGS could not be overcome by the inclusion of additional fat to the diets.

关键词： Amino acid digestibility Distillers dried grains with solubles Pigs

Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs

在线全文

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2014年第2期5卷 173-180页

作者： juliana Abranches soares Almeida Yanhong Liu Minho Song Jeong Jae Lee H Rex Gaskins Carol Wolfgang Maddox Orlando Osuna James Eugene Pettigrew Department of Animal Sciences University of IllinoisUrbana 61801USA Department of Animal Science and Biotechnology Chungnam National UniversityDaejeonSouth Korea Department of Pathobiology University of IllinoisUrbana 61801 USA Milwhite Inc.BrownsvilleTXUSA

An experiment was conducted to determine how an E. coil challenge and dietary clays affect the intestinal barrier of pigs. Two groups of 32 pigs （initial BW： 6.9 ± 1.0 kg） were distributed in a 2 x 4 factorial arrangement of a randomized complete block design （2 challenge treatments： sham or E. coil, and 4 dietary treatments： control, 0.3% smectite A, 0.3% smectite B and 0.3% zeolite）, with 8 replicates total. Diarrhea score, growth performance, goblet cell size and number, bacterial translocation from intestinal lumen to lymph nodes, intestinal morphology, and relative amounts of sulfo and sialo mucins were measured. The E. coli challenge reduced performance, increased goblet cell size and number in the ileum, increased bacterial translocation from the intestinal lumen to the lymph nodes, and increased ileal crypt depth. One of the clays （smectite A） tended to increase goblet cell size in ileum, which may indicate enhanced protection. In conclusion, E. coli infection degrades intestinal barrier integrity but smectite A may enhance it.

关键词： Barrier function E.coli Pigs Smectite Zeolite

Histological Assessment of Bone Regeneration in the Maxilla with Homologous Bone Graft:A Feasible Option for Maxillary Bone Reconstruction

在线全文

学校读者我要写书评

暂无评论

Journal of Renewable Materials 2024年第1期12卷 131-148页

作者： Sergio Henrique Gonçalves Motta Ana Paula Ramos soares juliana Campos Hasse Fernandes Gustavo Vicentis Oliveira Fernandes Graduate Center of Faculdade Redentor CLIVORio de JaneiroBrazil Periodontics and Oral Medicine Department University of Michigan School of DentistryAnn ArborMI48109USA Centre for Interdisciplinary Research in Health(CIIS) Universidade Católica PortuguesaViseu3504-505Portugal

Bone biomaterials have been increasingly used to reconstruct maxillary atrophic ***,the aim of this study was to evaluate bone reconstruction in the maxilla using a homologous cortico-cancellous FFB(lyophilized)graft and verify its *** individuals were included from 2014 to *** first surgery was performed to install homologous bone blocks in the *** period of the second intervention varied between 5 months and 15 days to 11 months(≈7.93 months).The biopsies were taken from the central region of the matured graft during the surgery for implant *** patients presented clinical and radiographic conditions for the installation of dental *** was a 100%of survival *** histological assessment showed that the homologous block bone graft was an osteoconductive biomaterial,with connective tissue present,and newly formed bone juxtaposed on its *** were bone trabeculae with osteocytes and active osteoblasts with connective tissue in the mineralization process;the remodeling process can be found through the reverse lines.A limited focus of necrosis with fibrosis was detected,with small resorption and areas of inflammatory infiltrate,but without clinical *** homologous block bone graft can be considered a feasible option to substitute the autogenous bone graft(gold standard),with predictable clinical and favorable histological *** patients had a shorter surgical period,low morbidity,and an unlimited amount of biomaterial available at an accessible cost.

关键词： Regeneration bone graft histology homologous allogenous autogenous

The Prevalence and Outcomes of Influenza Virus Infection in Heart Failure Patients in Brazil: Influenza Infection in Heart Failure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2015年第3期5卷 95-100页

作者： Henrique Godoy juliana soares Paula Zanellatto Neves N.C.J. Bellei Dirceu R. Almeida Division of Cardiology Department of Medicine Federal University of Sao Paulo Sao Paulo Brazil Hospital Epidemiology Committee Federal University of Sao Paulo Sao Paulo Brazil Clinical Virology Laboratory Division of Infectious Diseases Department of Medicine Federal University of Sao Paulo Sao Paulo Brazil

Background: Respiratory tract infections were associated with acute exacerbations of heart failure (HF). However, the role of the influenza virus, a major agent of such infections, in this population remained unclear. Method: During the influenza virus seasons of 2013 and 2014 we prospectively assessed influenza respiratory illnesses in a cohort of adults primarily hospitalized for management of acute decompensated HF and a cohort of HF outpatients. Qualitative RT-PCR for?influenza?A (A/H1, A/H12009pdm, A/H3) and B virus testing was performed on nasopharyngeal swab samples. Result: A total of 121 patients were included, 58.3% males (n?= 70), mean age 57.7 years old (±14.0), mean left ejection fraction 35.3 (±9.8). Of these, 50.4% were inpatients (n?= 61). The prevalence of symptoms of respiratory infections was 28.0% (n?= 34) and 4.9% (n?= 6) of all samples were positive for influenza virus. Only influenza A was detected and all cases were among inpatients. Influenza-positive patients had a greater need for antimicrobials (83.3%,?n?= 5;16.3%,?n= 9;?p?= 0.001) and for mechanical ventilation (50.0%,?n?= 3;3.6%,?n?= 2;?p?< 0.001) than Influenza-negative patients. The prevalence of influenza virus was not related to mortality (OR 4.58;?p?= 0.16). Conclusion:?Although not common, the influenza virus infection resulted in worst outcomes, with a greater need for antimicrobials and mechanical ventilation. Immunization and antiviral treatment in high risk patients may positively impact their outcomes.

关键词： Influenza Virus Heart Failure Epidemiology

Experimental and numerical analysis of multi-chamber oscillating water column devices

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2024年第3期36卷 492-503页

作者： Jorge Gadelho Kourosh Rezanejad C.Guedes soares Centre for Marine Technology and Ocean Engineering(CENTEC) Instituto Superior TécnicoUniversidade de LisboaAvenida Rovisco PaisLisboaPortugal

A review of multi-chamber oscillating water column(OWC)device designs is *** significant variations of these devices are discussed,onshore OWC(OOWC)and a floating OWC(FOWC).The efficiency results of several theoretical studies based on low-and high-fidelity numerical models are presented and compared with the model scale ***,low-fidelity numerical models are very fast to run,but their accuracy is limited compared with high-fidelity numerical *** model experiments usually give results much more accurate than numerical models,but they need adequate facilities and are very *** the case of the OOWC,all models show a similar trend of total efficiency,but while the analytical model shows a maximum value of around 90%efficiency,the CFD model shows 60%,and the experiments only go up to 40%.The main reason is connected with the mathematical simplifications and assumptions that do not represent all the hydrodynamic and aerodynamic processes between the water,air,and *** the case of the FOWC,interestingly,the experimental results show a maximum efficiency of almost 100%,while the analytical model only predicts a maximum of 80%.The efficiency seems highly dependent on the heave motion resonance of the entire device,where the analytical model fails to predict this natural frequency.

关键词： Wave energy converters oscillating water column(OWC) multi-chambers experimental modelling numerical modelling

Pharmacological Evaluation of Hexane Fraction of Casearia gossypiosperma Briquet： Antivenom Potentiality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Life Sciences 2014年第4期8卷 306-315页

作者： juliana de Oliveira soares-Silva Jhones Luiz de Oliveira José Carlos Cogo Renata Vasques da Silva Tavares Yoko Oshima-Franco University of Sorocaba (UNISO) Sorocaba 18023-000 SP Brazil Serpentarium of the Vale do Paraiba University CEN UNIVAP Sao José dos Campos 12244-000 SP Brazil

Neuromuscular junction is the main target for snakebites, which venoms act depending on the snake genus for paralyzing the prey （neurotoxicity） or for facilitating the digestion processes of the victim （myotoxicity）, and also as a defense mechanism against predators. In the present study, a mouse neuromuscular apparatus was used for testing the hexane fraction of Casearia gossypiosperma plant, that showed the better antiophidian ability than dichloromethane, ethyl acetate and methanol fractions, against the irreversible paralysis induced by two, Bothrops jararacussu （Bjssu, 40 μg/mL） and Crotalus durissus terrificus （Cdt, 10 μg/mL） snake venoms. All fractions were obtained by liquid-liquid partition from the C. gossypiosperma hydroalcoholic lyophilized extract. The preliminary chromatographic profile of this plant showed phenols and flavonols as active constituents, whereas hexane fraction expressed mainly 13-sitosterol and quercetin. In spite of hexane fraction protection （≌95% and 48% against Bjssu and Cdt, respectively）, isolately, only quercetin protected against the blockade-induced by Bjssu venom （65.5%）. This study showed that hexane fraction acts against these snake venoms by a synergistic phytocomplex mechanism.

关键词： Bothrops jararacussu Casearia gossypiosperma Briquet Crotalus durissus terrificus neuromuscular junction,pharmacological evaluation.

Larval development and voracity of Eupeodes americanus (Diptera: Syrphidae): comparison of the focal prey Aphis gossypi (Hemiptera: Aphididae) and the banker prey Rhopalosiphum padi (Hemiptera: Aphididae)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2024年第2期31卷 575-586页

作者： Arlette Fauteux Antonio Onofre soares Eric Lucas Laboratoire de lutte biologique Departement des sciences biologiquesUniversite du Quebec a Montreal(UQAM)MontrealQuebecCanada Faculty of Science and Technology Center for Ecology Evolution and Environmental ChangesAzorean Biodiversity Group(cE3c-ABG)&CHANGE-Global Change and Sustainability InstitutePonta DelgadaPortugal

Unlike European species,the potential of Nearctic syrphids as biological control agents is still poorly ***,the American hoverfly,Eupeodes americanus(Wiedemann),has recently demonstrated promising traits as a biocontrol agent,notably against the foxglove aphid,Aulacorthum solani Kaltenbach,on *** present study aims to extend our knowledge of the American hoverfly by evaluating its potential as a biocontrol agent in a banker plant system against the melon aphid,Aphis gossypi Glover,in a greenhouse cucumber *** preimaginal development and voracity of *** were compared when preying upon the focal prey/pest(***)or the banker prey(bird cherry-oat aphid,Rhopalosiphum padi L.)by daily observations of larvae from egg to *** development time,survival rate,and occurrence of deformation were similar on both prey *** weight of third instar and pupae,however,was higher for larvae that fed on the banker *** ad libitum voracity of the syrphid larvae was generally very high and did not significantly differ between prey species,except for the third-instar larvae which consumed more focal *** suggest that a banker plant system involving the bird cherry-oat aphid may be a promising tactic for utilizing *** for melon aphid biocontrol.

关键词： american hoverfly banker plant system biological control bird cherry-oat aphid greenhouse cucumber melon aphid

Liquid crystal immunosensors for the selective detection of Escherichia coli with a fast analysis tool

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第7期12卷 1564-1573页

作者： SANDRO C.OLIVEIRA MARIA S.soares BÁRBARA V.GONÇALVES ANDREIA C.M.RODRIGUES AMADEU M.V.M.soares RITA G.SOBRAL NUNO F.SANTOS JAN NEDOMA PEDRO L.ALMEIDA CARLOS MARQUES CICECO-Aveiro Institute of Materials Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal i3N Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal Associate Laboratory i4HB-Institute for Health and Bioeconomy School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal CESAM-Centre for Environmental and Marine Studies and Department of Biology University of Aveiro3810-193 AveiroPortugal Department of Telecommunications VSB-Technical University of OstravaOstrava 70800Czech Republic i3N-CENIMAT School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal UnIRE ISELPolytechnic Institute of Lisbon1549-020 LisbonPortugal Department of Physics VSB-Technical University of OstravaOstrava 70800Czech Republic

The consumption of contaminated food may cause serious illnesses,and traditional methods to detect Escherichia coli are still associated with long waiting times and high costs given the necessity to transport samples to specialized *** is a need to develop new technologies that allow cheap,fast,and direct monitoring at the site of ***,in this work,we developed optical immunosensors for the selective detection of ***,based on liquid crystal technology,whose molecules can align in different manners depending on the boundary conditions (such as substrates) as well as the environment that they *** glass substrate was functionalized with *** antibody using cysteamine as an intermediate,and a vertical alignment was imposed on the liquid crystal molecules by using DMOAP during *** presence of bacteria disrupts the alignment of the liquid crystal molecules,changing the intensity of light emerging between cross polarizers,measured using a polarized optical microscope and a *** was possible to detect *** in suspensions in the concentration range from 2.8 cells/mL to 2.8×10^(9) cells∕*** was also evaluated,and the sensors were used to analyze contaminated water samples.A prototype was developed to allow faster,in-situ,and easier analysis avoiding bulky instruments.

关键词： crystal alignment analysis

Optimizing ASReview Simulations:A generic Multiprocessing Solution for“Light-data'and“Heavy-data'Users

在线全文

学校读者我要写书评

暂无评论

Data Intelligence 2024年第2期6卷 320-343页

作者： Sergei Romanov Abel soares Siqueira Jonathan de Bruin Jelle Teijema Laura Hofstee Rens van de Schoot Applied Data Science Department of Information and Computing ScienceFaculty of ScienceUtrecht University Netherlands eScienceCenter AmsterdamNL Department of Research and Data Management Services Information Technology ServicesUtrecht UniversityUtrechtthe Netherlands Department of Methodology and Statistics Faculty of Social and Behavioral SciencesUtrecht University

Active learning can be used for optimizing and speeding up the screening phase of systematic *** simulation studies mimicking the screening process can be used to test the performance of different machine-learning models or to study the impact of different training *** paper presents an architecture design withamultiprocessing computational strategyforrunningmanysuch simulation studiesinparallel,using the ASReview Makita workflow generator and Kubernetes software for deployment with cloud *** provide a technical explanation of the proposed cloud architecture and its *** addition to that,we conducted 1140 simulations investigating the computational time using various numbers of CPUs and RAM *** analysis demonstrates the degree to which simulations can be accelerated with multiprocessing computing *** parallel computation strategy and the architecture design that was developed in the present paper can contribute to future research with more optimal simulation time and,at the same time,ensure the safe completion of the needed processes.

关键词： Active learning Systematic review Simulation study Multiprocessing Cloud architecture