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Original Antigenic Sin on Antibody Response in SARS-CoV-2 Infection

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Infectious Diseases & Immunity 2024年第3期4卷 132-137页

作者： Miao Wang Huimin Guo Bin ju zheng Zhang Institute for Hepatology National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhen 518112Guangdong ProvinceChina Guangdong Key Laboratory for Anti-infection Drug Quality Evaluation Shenzhen 518112Guangdong ProvinceChina Shenzhen Research Center for Communicable Disease Diagnosis and Treatment Chinese Academy of Medical SciencesShenzhen 518112Guangdong ProvinceChina

Infection and vaccination can provide protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the emergence of SARS-CoV-2 variants has persisted, leading to breakthrough infections. Owing to the original antigenic sin (OAS), variant breakthrough infection or vaccination potentially induces a stronger antibody response against the ancestral strain than to subsequent variants, as in the case of influenza. Thus, overcoming OAS is important for the development of future vaccine designs. This review summarizes the recent findings on OAS in the antibody response to SARS-CoV-2 and its variants, with an emphasis on future vaccine designs.

关键词： SARS-CoV-2 Original antigenic sin Antibody response Omicron subvariants Vaccine design

A novel insight of degradation ibuprofen in aqueous by catalytic ozonation with supported catalyst:Supports effect on ozone mass transfer

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Journal of Environmental Sciences 2024年第11期145卷 216-231页

作者： Zizheng Huangfu Wei ju Yunhan Jia Ruijun Ren Zhenbei Wang Chen Li Xiaomeng Shang Yujie Li Hongnan Liu YuWang Hao zheng Fei Qi Amir Ikhlaq Jolanta Kumirska Ewa Maria Siedlecka Beijing Key Laboratory for Source Control Technology of Water Pollution College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Beijing Forestry University Science Co. Ltd.Beijing 100083China Institute of Environment Engineering and Research University of Engineering and TechnologyLahore 54890Pakistan Department of Environmental Analysis Faculty of ChemistryUniversity of GdanskWita Stwosza 6380-308Poland

Catalytic ozonation is an effective wastewater purification ***,the low ozone mass transfer in packed bubble columns leads to low ozone utilization efficiency(OUE),poor organic degradation performance,and high energy ***,there is an urgent need to develop efficient supported catalysts that can enhancemass transfer and ***,the reaction mechanism of the support on ozone mass transfer remains unclear,which hinders the development of catalytic ozonation *** this study,lava rocks(LR)-supported catalysts,specifically CuMn_(2)O_(4)@LR and MnO_(2)–Co_(3)O_(4)@LR,were proposed for catalytic ozonation of IBP degradation due to their superior catalytic activity,stability,and high *** of CuMn_(2)O_(4)@LR or MnO_(2)–Co_(3)O_(4)@LR increased IBP removal efficiency from 85%to 91%or 88%,and reduced energy consumption from 2.86 to 2.14 kWh/m^(3)or 2.60 kWh/m^(3),*** improvement was attributed to LRsupported catalysts enhancing mass transfer and promoting O3 decomposition to generate•OH and•O_(2)^(−),leading to IBP ***,this study investigated the effects of ozone dose,supporter sizes,and catalyst components on ozone-liquid mass *** results revealed that the size of the supporter influenced stacked porosity and consequently affected ozone mass ***-sized LR(kLa=0.172 min^(−1))exhibited better mass transfer compared to smaller-sized *** on these findings,it was concluded that both CuMn_(2)O_(4)@LR and MnO_(2)–Co_(3)O_(4)@LR are potential catalysts for catalytic ozonation in residual IBP degradation of pharmaceutical wastewater,and LR showed good credibility as a catalyst *** the effects of supporters and active components on ozone mass transfer provides a fundamental principle for designing supported catalysts in catalytic ozonation applications.

关键词： Catalytic ozonation Lava rocks Overall volumetric mass transfer coefficient Supported catalyst

北朝覆头裹背式僧服流变及其与禅修实践的关联性

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艺术百家 2023年第5期39卷 141-148页

作者：陆一郑巨欣中国美术学院手工艺术学院浙江杭州310002

在佛教僧服形象中,有一种一块方布覆盖头部及后背的服饰样式,名曰“覆头裹背式僧服”,相较于其他样式,其受到的关注较少。此类样式经常被早期的林间坐禅僧使用,甚至延续到现在的僧服之中。论文梳理辨析此类僧服样式的形象在古印度、龟... 详细信息

在佛教僧服形象中,有一种一块方布覆盖头部及后背的服饰样式,名曰“覆头裹背式僧服”,相较于其他样式,其受到的关注较少。此类样式经常被早期的林间坐禅僧使用,甚至延续到现在的僧服之中。论文梳理辨析此类僧服样式的形象在古印度、龟兹、吐峪沟、敦煌、云冈等地的流传变化,结合新见南涅水石刻、晋城北齐昙始造像碑座上的交领覆头裹背式图像,探寻此类僧服样式在北地汉化进程中对左衽右衽的选择以及在禅修实践中的使用情况。

关键词：北朝造像覆头裹背式僧服禅修

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一种高超声速飞行器鲁棒自适应控制方法

宇航学报 2017年第10期38卷 1088-1096页

作者：余朝军江驹肖东郑亚龙南京航空航天大学自动化学院南京211106

针对较强参数摄动情况下高超声速飞行器巡航段控制问题,提出一种基于主影响元素分析的鲁棒自适应控制方法。首先在飞行器具有未知参数情况下,使用符号计算工具对系统不确定量进行分离,实现不确定性的建模;进一步使用蒙特卡洛试验方法,... 详细信息

针对较强参数摄动情况下高超声速飞行器巡航段控制问题,提出一种基于主影响元素分析的鲁棒自适应控制方法。首先在飞行器具有未知参数情况下,使用符号计算工具对系统不确定量进行分离,实现不确定性的建模;进一步使用蒙特卡洛试验方法,确定不确定函数向量的主影响元素,对模型进行简化。然后在滑模控制的基础上,结合参数自适应估值和鲁棒补偿的方法,设计出飞行控制器,实现对未知参数的自适应估值以及对模型误差的补偿,并从理论上证明了系统的稳定性。仿真试验表明,在较大参数摄动情况下,文中所提方法依然可以保证系统的稳定性和跟踪性能。

关键词：高超声速飞行器不确定性建模主影响元素分析鲁棒自适应控制

三网融合背景下4G通信技术在互联网电视中的运用

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西南师范大学学报（自然科学版） 2017年第9期42卷 121-127页

作者：朱居正郑州工商学院现代教育技术中心郑州451400

现代网络技术的不断发展,使得"三网融合"大背景逐渐形成,在此背景下我国的第四代通信技术(4G技术)也正以快速的步伐跨入人们的生活,并逐渐取代3G通信技术在通讯市场的地位.通过对4G通信技术的概念、关键技术、运用特点等方面进行分析,... 详细信息

现代网络技术的不断发展,使得"三网融合"大背景逐渐形成,在此背景下我国的第四代通信技术(4G技术)也正以快速的步伐跨入人们的生活,并逐渐取代3G通信技术在通讯市场的地位.通过对4G通信技术的概念、关键技术、运用特点等方面进行分析,探讨三网融合背景下4G通信技术在互联网电视中的运用情况.

关键词：三网融合 4G通信技术互联网电视

Novel Tuning Buttons in Tomato Fruit Ripening:miRNAs and siRNAs

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Agricultural Science & Technology 2016年第7期17卷 1541-1545页

作者： Jinhua ZUO Qing WANG zheng ju Dongyan CAO Benzhong ZHU Yunbo LUO Lipu GAO National Engineering Research Center for Vegetables Beijing 100097 China Beijing Key Laboratory of Fruits and Vegetable Storage and Processing Beijing 100097 China College of Food Science and Nutritional Engineering China Agricultural University Beijing 100083 China

Tomato has emerged as an emblematic model plants for fleshy fruit research and tomato fruit ripening is a complex and highly coordinated developmental *** many physiology and biochemical processes associated with tomato fruit ripening require changes in the expression of hundreds to thousands of *** expression is regulated by transcriptional and post-transcriptional pathways,one of the recently discovered mechanisms in plants was small RNAs mediated gene silencing at post-transcriptional(PTGS) ***,several mi RNAs and endogenous si RNAs were revealed to be involved in the fruit ripening process which opened a new avenue in the field of fleshy fruit *** review compiled the most recent advances made in deciphering the regulation functions of mi RNAs and si RNAs in tomato fruit *** also emphasized the new perspectives now possible in the small RNAs regulation research in tomato fruit ripening and senescence.

关键词： tomato siRNAs hundreds developmental emphasized Ethylene biochemical endogenous coordinated miRNAs

Angiographic leakage of polypoidal choroidal vasculopathy on indocyanine angiography

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Chinese Medical Journal 2010年第12期123卷 1548-1552页

作者： ZUO Cheng-guo WEN Feng HUANG Shi-zhou LUO Guang-wei YAN Hong WU Wei-ju WU De-zheng State Key Laboratory of Ophthalmology Zhongshan OphthalmicCenter Sun Yat-sen University Guangzhou Guangdong 510060China

Background There is no detailed report about the angiographic leakage of polypoidal choroidal vasculopathy （PGV） lesions on indocyanine green （ICG） angiography. This study aimed to investigate the angiographic leakage of polypoidal lesions in PCV on ICG angiography. Methods One hundred and forty-four eyes of 137 patients diagnosed as PCV were prospectively observed. Fundus examination, fluorescein angiography, and ICG angiography were performed. Leakage of polypoidal lesions and clinical features were recorded according to the angiograms. Results In all 144 eyes, 110 eyes showed angiographic leakage （leakage group） on ICG angiography and three subtypes of leakage group were noted, which were polypoidal dilations leakage （47 eyes, 42.7%）, branching vascular networks leakage （14 eyes, 12.7%） and leakage of both （49 eyes, 44.5%）. The other 34 eyes showed regression of polypoidal lesions （regression group）. In leakage group, the rates of pigment epithelial detachment （PED）, best corrected visual acuity （BCVA）〈0.1 and old subretinal hemorrhages were 56.4% （62 eyes）, 19.1% （21 eyes）, and 4.6% （5 eyes） respectively, compared with 8.8% （3 eyes）, 50% （17 eyes） and 38.2% （13 eyes） of regression group （P 〈0.001）. The history of regression group was significantly longer （P 〈0.001）. Conclusions Angiographic leakage and regression can be observed in PCV lesions. Leakage of both polypoidal dilations and branching vascular networks is the most common subtype in leakage group. PCV in leakage group is more likely to be related to PED, better BCVA and shorter history, while PCV regression group tends to relevant to old subretinal hemorrhage, worse BCVA and longer history. This may reflect that the former is active or in the early course while the later is resting or in the late phase of PCV.

关键词： classification indocyanine green angiography polypidal choroidal vasculopathy