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Neural Regeneration Research 2022年第2期17卷 311-312页

作者： Ken-ichiro tanaka Mikako Shimoda Masahiro Kawahara Department of Bio-Analytical Chemistry Faculty of PharmacyMusashino UniversityShinmachiNishitokyoTokyoJapan

In many tissues, trace metals such as iron(Fe), zinc(Zn), and copper(Cu) are important for various physiological functions such as immune function, cell division, and enzyme function. However, it has been shown in humans and experimental animal models that excessive amounts of these trace metals in the body can induce various diseases in the central nervous system, liver.

关键词： metals potential copper

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Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

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Oncology Research 2024年第8期32卷 1369-1370页

作者： HUI SUN MASANORI KAWANO TATSUYA IWASAKI ichiro ITONAGA YUTA KUBOTA HIROSHI TSUMURA KAZUHIRO tanaka Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−***:10.32604/or.2023.044085),there was an error in the compilation of *** have revised Fig.8D to correct this error.A corrected version of Fig.8 is *** correction does not change any results or conclusions of the *** apologize for any inconvenience caused.

关键词： osteosarcoma correction revised

Statistical evaluation of cluster formation of relapse in neuromyelitis optica spectrum disorder

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Neural Regeneration Research 2024年第9期19卷 1888-1889页

作者： Tetsuya Akaishi ichiro Nakashima Department of Neurology Tohoku UniversitySendaiJapan Department of Neurology Tohoku Medical and Pharmaceutical UniversitySendaiJapan

Evaluating the cluster formation of clinical attacks in chronic relapsing diseases is an important statistical issue because the presence of attack clusters may influence therapeutic strategies for relapse *** recently reported the occurrence of unevenly clustered attacks in patients with anti-aquaporin-4(AQP4)antibody-positive neuromyelitis optica spectrum disorder(NMOSD)(Akaishi et al.,2020a).

关键词： AQP4 relapse

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Cell-Based Microfluidic Device Utilizing Cell Sheet Technology

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Cyborg and Bionic Systems 2022年第1期2022卷 35-42页

作者： Katsuhisa Sakaguchi Kei Akimoto Masanori Takaira Ryu-ichiro tanaka Tatsuya Shimizu Shinjiro Umezu Department of Integrative Bioscience and Biomedical Engineering Graduate School of Advaneed Science and Enginring TWInsWaseda University2-2 Wakamatsu-ChoShinju-KuTokyo 162-8480Japan Department of Modern Mechanical Engineering Graduate School of Creative Science and Engineering Waseda University 1-104 Totsuka-ChoShinju-KuTokyo 169-8555Japan Insttute of Advanced BiomedicalEngineering and Seience TWIns Tokyo Women's Medical University8-1 Kawada-ChoShinju-KuTokyo 162-8666Japan

The developmentof microelectromechanical systems hasresulted in the rapid development of polydimethylpolysiloxane(PDMS)microfluidic devices for drug screening *** cell functions,such as the response of endothelial cells to fluids,have beenelucdated using microuidic ***,organon-achip systems that includeorgans that are importantfor biologicalcirculation,such as the heart,liver,pancreas,kidneys,and brain,have been *** organs realize the biologicalcirculation system in a manner that cannot be reproduced by artificial organs;however,the flow channels between the organsare often artifically created by *** this study,we developeda microfluidic device consisting only of cels,by combiningcell sheet technology with microtitanium *** were placed between stacked fibroblast cellsheets,and the celisheets adhered to each other,afer which the microwires were removed leaving a luminal structure with a size approximatelyequal to the arteriolar *** lumen structure was constructed using wires with diameters of 50,100,150,and 200μm,which were approximations of the arteriole *** using a perfusion device,we successfully perfused theluminal structure created inside the *** results revealed that a aulture solution can be supplied toa cellsheet witha very high cell *** biofabrication technology proposed in this study can contribute to the development of organ-on-a-chip systems.

关键词： organs fluid diameters

Optimized Distribution and Morphology of Carbon Nanofibers for a Field Emitter Grown by Nickel and Chromium Cosputtering

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Materials Sciences and Applications 2013年第4期4卷 225-230页

作者： Norihiro Shimoi Shun-ichiro tanaka Graduate School of Environmental Studies Tohoku University of Aoba Sendai Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku University Katahira Sendai Japan

To obtain a high field emission (FE) current with a low driving voltage, it is important to control and optimize carbon nanofiber (CNF) array patterns for FE. While there have been various means for controlling CNF array patterns reported over the past few decades, array patterning using lithography is the method typically used to control CNF morphology. Because lithography uses many masks and is costly, it is necessary to establish a simpler process. In this study, the grain size and distribution of catalysts with phase separation were controlled. A system which controls the morphology of small bundles of CNFs was constructed with the distance between the bundles kept constant in order to obtain a higher FE current. The Ni catalyst layer for forming the CNF morphology was separated by noncatalytic Cr grains formed by cosputtering. As a result, it was possible to control the Ni content, the grain size and synthesis density of CNFs in the alloy with a varying number of nickel pellets placed on the chromium target. This method is an epochmaking CNF patterning technique very different from lithography.

关键词： Alloys Carbon Fibres Metal-Matrix Composites X-Ray Diffraction Chemical Vapour Deposition (CVD)

Assessing mixing uniformity in microreactors via in-line spectroscopy

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Chinese Journal of Chemical Engineering 2024年第2期66卷 119-124页

作者： Shusaku Asano Shinji Kudo Taisuke Maki Yosuke Muranaka Kazuhiro Mae Jun-ichiro Hayashi Institute for Materials Chemistry and Engineering Kyushu UniversityKasuga 816-8580Japan Department of Chemical Engineering Graduate School of EngineeringKyoto UniversityJapan

Mixing behavior is critical for enhancing the selectivity of fast chemical reactions in microreactors.A high Reynolds number(Re)improves the mixing rate and selectivity of the reactions,but some exceptions of increasing side product yield with the higher Re have been *** study investigated the mixing uniformity in microreactors with in-line UV-vis spectroscopy to clarify the relationship between reaction selectivity and chaotic mixing with the higher Re.A colorization experiment of thymolphthalein in an acidic solution was conducted with an excess acid amount to the base to indicate a non-uniformly mixed ***-uniformity significantly increased with *** the same time,the degree of mixing,which was measured by a usual decolorization experiment,showed that the mixing rate increased with *** in-line analysis of the Villermaux-Dushman reaction during the mixing clarified that side product yield significantly increased with Re at around 300 and then decreased at around *** results suggest the compensation effect between the mixing uniformity and mixing rate on the selectivity of the mixing-sensitive *** mixing,characterized by a larger Re,can disturb mixing uniformity and,in some cases,decrease reaction selectivity.

关键词： Microreactor Villermaux-Dushman reaction In-line analysis Mixing Mass transfer Uniformity

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Gastrointestinal stromal tumor presenting with prominent calcification

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World Journal of Gastroenterology 2012年第39期18卷 5645-5648页

作者： Naoki Izawa Takeshi Sawada Ryuichi Abiko Daisuke Kumon Mami Hirakawa Mika Kobayashi Nobuyuki Obinata Masahito Nomoto Tadateru Maehata Shun-ichi Yamauchi Takefumi Kouro Takashi Tsuda Satoshi Kitajima Hiroshi Yasuda Keiichi tanaka ichiro tanaka Masahiro Hoshikawa Masayuki Takagi Fumio Itoh Division of Gastroenterology and Hepatology St.Marianna University School of MedicineKawasaki 216-8511Japan Division of Gastroenterological and General Surgery St.Marianna University School of MedicineKawasaki 216-8511Japan Department of Pathology St.Marianna University School of MedicineKawasak 216-8511Japan

We present a rare case of a gastrointestinal stromal tumor (GIST) in the stomach with prominent calcifica-tion at presentation. A 61-year-old woman visited our hospital because of epigastric discomfort. A spherical calcified lesion with a diameter of about 30 mm was incidentally shown in the left upper quadrant on an abdominal X-ray. Computed tomography demonstrated that the tumor was growing from the upper gastric body, with calcification in the peripheral ring area. A laparoscopic partial gastrectomy was performed, and the resected specimen revealed a well-circumscribed tumor with exophytic growth from the gastric muscularis propria. Microscopic examination revealed spindle- shaped tumor cells with calcification and hemorrhage. Additionally, positive immunoreactivity of the tumor to KIT and CD34 and a low mitotic index resulted in the diagnosis of very low risk GIST. There are a few case reports of heavily calcified GIST, although solitary or punctate calcification of primary GIST has been reported in several case series. Dystrophic calcification of necrotic or degenerative tissue is the supposed cause of primary calcified GISTs. In contrast, appearance of calcification after administration of imatinib mesylate, which may be one indicator of disease response, is possibly caused by a different mechanism.

关键词：胃肠道钙化间质肿瘤生长突出有丝分裂指数肿瘤细胞 CD34

A Hydrogen-Bonded,Hexagonally Networked,Layered Framework with Large Aperture Designed by Structural Synchronization of a Macrocycle and Supramolecular Synthon

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Precision Chemistry 2024年第5期2卷 221-228页

作者： Hiroki Yoshimura Ryusei Oketani Miki Naruoka Norimitsu Tohnai ichiro Hisaki Division of Chemistry Graduate School of Engineering ScienceOsaka UniversityToyonakaOsaka 560-8531Japan Department of Applied Chemistry Graduate School of EngineeringOsaka UniversitySuitaOsaka 565-0871Japan

To develop porous organic frameworks,precise control of the stacking manner of two-dimensional porous motifs and structural characterization of the resultant framework are *** these points of view,porous molecular crystals formed through reversible intermolecular hydrogen bonds,such as;hydrogen-bonded organic frameworks(HOFs),can provide deep insight because of their high crystallinity,affording single-crystalline X-ray diffraction *** this study,we demonstrate that the stacking manner of hydrogen-bonded hexagonal network(HexNet)sheets can be controlled by synchronizing a homological triangular macrocyclic tecton and a hydrogen-bonded cyclic supramolecular synthon called the phenylene triangle.A structure of the resultant HOF was crystallographically characterized and revealed to have a large channel aperture of 2.4 *** HOF also shows thermal stability up to 290°C,which is higher than that of the conventional HexNet frameworks.

关键词： hydrogen-bonded organicframeworks hexagonalnetwork macrocycle carboxylicacid porosity

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使用轻质材料减轻发动机重量

汽车与新动力 1994年第5期 40-46页

作者： ichiro tanaka Toshiro Shimamoto 宋进桂

介绍通过使用轻质材料来降低发动机质量的一些方法。利用一台作者制造的轻质试验发动机(后称减重发动机)对其效率和性能进行了评价。它是一台直列、4缸、2.0L的汽油机。原型标准发动机重162kg(含机油和冷却水),而通过使用轻质材料和新... 详细信息

介绍通过使用轻质材料来降低发动机质量的一些方法。利用一台作者制造的轻质试验发动机(后称减重发动机)对其效率和性能进行了评价。它是一台直列、4缸、2.0L的汽油机。原型标准发动机重162kg(含机油和冷却水),而通过使用轻质材料和新的制造技术减重37kg,相当于减重23%。这台减重发动机使用的材料是钢53%,铝33%,塑料7%,其它轻质材料7%。通过使用轻质材料,可以改善发动机的性能,即改善响应性和减少摩擦损失。这些轻量部件已进行了各种试验,包括部件疲劳试验和用它们装配的发动机进行的倒拖和着火台架试验。试验结果表明,这些部件的耐久性足以用于实际工作环境。

关键词：汽车发动机部件材料重量试验

Refinement of Adaptive Dynamical Simulation of Quantum Mechanical Double Slit Interference Phenomenon

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Journal of Modern Physics 2024年第3期15卷 239-249页

作者： Tadashi Ando Andrei Khrennikov ichiro Yamato Department of Applied Electronics Tokyo University of Science Tokyo Japan International Center for Mathematical Modelling in Physics and Cognitive Sciences Linnaeus University V&aumlxj&oum Sweden Department of Biological Science and Technology Tokyo University of Science Tokyo Japan

We applied adaptive dynamics to double slit interference phenomenon using particle model and obtained partial successful results in our previous report. The patterns qualitatively corresponded well with experiments. Several properties such as concave single slit pattern and large influence of slight displacement of the emission position were different from the experimental results. In this study we tried other slit conditions and obtained consistent patterns with experiments. We do not claim that the adaptive dynamics is the principle of quantum mechanics, but the present results support the probability of adaptive dynamics as the candidate of the basis of quantum mechanics. We discuss the advantages of the adaptive dynamical view for foundations of quantum mechanics.

关键词： Double Slit Interference Adaptive Dynamics Quantum Mechanics Particle Model Simulation