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Effects of selenium-containing compounds on Cu^(2+)/Zn^(2+)-induced neuronal cell death and potential application as therapeutic agents for neurological diseases

Effects of selenium-containing compounds on Cu2+/Zn2+-induced neuronal cell death and potential application as therapeutic agents for neurological diseases

作     者:Ken-ichiro Tanaka Mikako Shimoda Masahiro Kawahara 

作者机构:Department of Bio-Analytical ChemistryFaculty of PharmacyMusashino UniversityShinmachiNishitokyoTokyoJapan 

出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))

年 卷 期:2022年第17卷第2期

页      面:311-312页

核心收录:

学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基  金:supported by grants from The Research Foundation for Pharmaceutical Sciences(to Ki T) in part by a Grant-inAid for Scientific Research from Japan Society for the Promotion of Science(JSPS)[KAKENHI KIBAN(C)18K06669](to MK) 

主  题:metals potential copper 

摘      要:In many tissues, trace metals such as iron(Fe), zinc(Zn), and copper(Cu) are important for various physiological functions such as immune function, cell division, and enzyme function. However, it has been shown in humans and experimental animal models that excessive amounts of these trace metals in the body can induce various diseases in the central nervous system, liver.

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