检索结果-南通市图书馆

High-Index Faceted Nanocrystals as Highly Efficient Bifunctional Electrocatalysts for High-Performance Lithium-Sulfur Batteries

引用

Nano-Micro Letters 2022年第2期14卷 324-338页

作者： Bo Jiang Da Tian Yue Qiu Xueqin Song Yu Zhang Xun Sun huihuang huang Chenghao Zhao Zhikun Guo Lishuang Fan Naiqing Zhang State Key Laboratory of Urban Water Resource and Environment School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Energy Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Precisely regulating of the surface structure of crystalline materials to improve their catalytic activity for lithium polysulfides is urgently needed for high-performance lithium-sulfur(Li-S)***,high-index faceted iron oxide(Fe_(2)O_(3))nanocrystals anchored on reduced graphene oxide are developed as highly efficient bifunctional electrocatalysts,effectively improving the electrochemical performance of Li-S *** theoretical and experimental results all indicate that high-index Fe_(2)O_(3)crystal facets with abundant unsaturated coordinated Fe sites not only have strong adsorption capacity to anchor polysulfides but also have high catalytic activity to facilitate the redox transformation of polysulfides and reduce the decomposition energy barrier of Li_(2)*** Li-S batteries with these bifunctional electrocatalysts exhibit high initial capacity of 1521 mAh g^(-1)at 0.1 C and excellent cycling performance with a low capacity fading of 0.025%per cycle during 1600 cycles at 2 *** with a high sulfur loading of 9.41 mg cm^(-2),a remarkable areal capacity of 7.61 mAh cm^(-2)was maintained after 85 *** work provides a new strategy to improve the catalytic activity of nanocrystals through the crystal facet engineering,deepening the comprehending of facet-dependent activity of catalysts in Li-S chemistry,affording a novel perspective for the design of advanced sulfur electrodes.

关键词： High-index faceted Fe_(2)O_(3)nanocrystals Unsaturated coordinated Lithium-sulfur batteries Electrocatalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The role of neutrophils in the development of liver diseases

引用

Cellular & Molecular Immunology 2014年第3期11卷 224-231页

作者： Ruonan Xu huihuang huang Zheng Zhang Fu-Sheng Wang The Institute of Translational Hepatology Research Center for Biological Therapy Beijing 302 Hospital Beijing China he Institute of Intensive Care Unit Beijing 302 Hospital Beijing China These authors contributed equally to this study

Liver disease encompasses a wide variety of liver conditions, including liver failure, liver cirrhosis and a spectrum of acute and chronic hepatitis, such as alcoholic, fatty, drug, viral and chronic hepatitis. Liver injury is a primary causative factor in liver disease; generally, these factors include direct liver damage and immune-mediated liver injury. Neutrophils （also known as neutrophilic granulocytes or polymorphonuclear leukocytes （PMNs）） are the most abundant circulating white blood cell type in humans, and PMNs are a major innate immune cell subset. Inappropriate activation and homing of neutrophils to the microvasculature contributes to the pathological manifestations of many types of liver disease. This review summarizes novel concepts of neutrophil-mediated liver iniurv that are based on current clinical and animal model studies.

关键词： liver disease liver injury neutrophil

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

自主创新税收优惠政策的实证分析

引用

涉外税务 2007年第11期 14-18页

作者：黄辉煌漳州市国家税务局福建漳州363000

本文对我国自主创新的基本情况进行了简要说明和国际比较,并选取福建省2002～2006年数据,以线性回归分析说明了高新技术产业内部研究与开发(R&D)投入与减免税政策间的相关性。以此为基础,从体系设计、作用环节对象、政策工具选择和税制... 详细信息

本文对我国自主创新的基本情况进行了简要说明和国际比较,并选取福建省2002～2006年数据,以线性回归分析说明了高新技术产业内部研究与开发(R&D)投入与减免税政策间的相关性。以此为基础,从体系设计、作用环节对象、政策工具选择和税制因素等方面指出了现行税收优惠政策体系中存在的一些问题,有针对性地提出了改进和完善建议。

关键词：自主创新税收优惠实证分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Human umbilical cord mesenchymal stem cell transfusion in immune non-responders with AIDS:a multicenter randomized controlled trial

引用

Signal Transduction and Targeted Therapy 2021年第7期6卷 2164-2171页

作者： Lifeng Wang Zheng Zhang Ruonan Xu Xicheng Wang Zhanjun Shu Xiejie Chen Siyu Wang Jiaye Liu Yuanyuan Li Li Wang Mi Zhang Wei Yang Ying Wang huihuang huang Bo Tu Zhiwei Liang Linghua Li Jingxin Li Yuying Hou Ming Shi Fu-Sheng Wang Treatment and Research Center for Infectious Diseases Fifth Medical Center of Chinese PLA General HospitalBeijingChina lnstitute of Hepatology National Clinical Research Center for Infectious DiseaseShenzhen Third Peopled HospitalThe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Yunnan Provincial Hospital of Infectious Diseases KunmingChina Xinjiang Uygur Autonomous Regional the Sixth People's Hospital UrumqiChina Guangzhou Eighth Peopled Hospital Guangzhou Medical UniversityGuangzhouChina NHC Key Laboratory of Enteric Pathogenic Microbiology Jiangsu Provincial Center for Disease Control and PreventionNanjingChina

We examined the safety and efficacy of human umbilical cord mesenchymal stem cell(hUC-MSC)infusion for immune nonresponder(INR)patients with chronic HIV-1 infection,who represent an unmet medical need even in the era of efficient antiretroviral therapy(ART).Seventy-two INR patients with HIV were enrolled in this phase II randomized,double-blinded,multicenter,placebo-controlled,dose-determination trial(NCT01213186)from May 2013 to March *** were assigned to receive high-dose(1.5 x 106/kg body weight)or low-dose(0.5 x 106/kg body weight)hUC-MSC,or *** clinical and immunological parameters were monitored during the 96-week follow-up *** found that hUC-MSC treatment was safe and *** with baseline,there was a statistical increase in CD4+T counts in the high-dose(P<0.001)and low-dose(P<0.001)groups after 48-week treatment,but no change was observed in the control ***-Meier analysis revealed a higher cumulative probability of achieving an immunological response in the low-dose group compared with the control group(95.8%vs.70.8%,P=0.00A).However,no significant changes in CD4/CD84-T counts and CD4/CD8 ratios were observed among the three *** summary,hUC-MSC treatment is ***,the therapeutic efficacy of hUC-MSC treatment to improve the immune reconstitution in INR patients still needs to be further investigated in a large cohort study.

关键词： CD4/CD8 transfusion randomized

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High levels of circulating GM-CSF^(+) CD4^(+) T cells are predictive of poor outcomes in sepsis patients: a prospective cohort study

引用

Cellular & Molecular Immunology 2019年第6期16卷 602-610页

作者： huihuang huang Siyu Wang Tianjun Jiang Rong Fan Zheng Zhang Jinsong Mu Ke Li Yonggang Wang Lei Jin Fang Lin Jie Xia Lijian Sun Biao Xu Chengcheng Ji Jing Chen Juan Chang Bo Tu Bing Song Chao Zhang Fu-Sheng Wang Ruonan Xu Treatment and Research Center for Infectious Disease Beijing 302 HospitalBeijingChina Clinical Research and Management Center Beijing 302 HospitalBeijingChina Intensive Care Center Beijing 302 HospitalBeijingChina Treatment and Research Center for Liver Failure Beijing 302 HospitalBeijingChina Department of Infectious Diseases The Affiliated Southwest Hospital of the Third Military Medical UniversityChongqingChina Medical Department Army General Hospital of PLABeijingChina

Granulocyte colony-stimulating factor(GM-CSF),produced by CD4^(+)T cells,has recently been implicated in the pathogenesis of inflammatory diseases,such as multiple sclerosis and juvenile ***,the role of GM-CSF-producing CD4^(+)T cells in sepsis remains *** study reports peripheral changes in GM-CSF-producing CD4^(+)T cells in septic patients and the possible underlying mechanism by which GM-CSF influences the outcome of ***-three septic patients,20 SIRS patients,and 20 healthy controls were enrolled in this study and followed for 28 days to assess *** measured the peripheral frequency of GM-CSF^(+)CD4^(+)T cells and recorded their associated relationship with disease *** data demonstrated that peripheral GM-CSF-producing CD4^(+)T cells were significantly higher in septic patients than in both SIRS patients and healthy *** cells exhibit a memory phenotype and impaired IFN-γ-secreting capacity in sepsis *** a receiver operating curve analysis with 8.01%as a cut-off point,the percentage of GM-CSF^(+)CD4^(+)T cells could predict the outcome of septic *** with the increase in GM-CSF-producing CD4^(+)T cells,inflammatory cytokines IL-1βand IL-6 were also *** an in vitro neutrophil model,we found that GM-CSF inhibited C3aR expression,while inducing IL-8 ***,this effect was transferrable in plasma from sepsis patients and was attenuated by inhibition of GM-CSF using an anti-GM-CSF *** results indicate that GM-CSF-producing CD4^(+)T cells may serve as a marker of sepsis ***,targeting GM-CSF overproduction may benefit sepsis patients.

关键词： GM-CSF CD4^(+)T cells sepsis SIRS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis

引用

Cellular & Molecular Immunology 2016年第1期13卷 103-109页

作者： Ruonan Xu Fang Lin Chunmei Bao huihuang huang Chengcheng Ji Siyu Wang Lei Jin Lijian Sun Ke Li Zheng Zhang Fu-Sheng Wang Research Centre for Biological Therapy The Institute of Translational Hepatology Beijing 302 Hospital Beijing China The Institute of Intensive Care Unit Beijing 302 Hospital Beijing China Centre of Clinical Laboratory Medicine Beijing 302 Hospital Beijing China

Complement 5a （C5a） has been implicated in the pathogenesis of sepsis by inducing the functional impairment of neutrophils; however, the utility of C5a receptors （C5aRs; C5aR and C5L2） as biomarkers for the management of sepsis is uncertain. This study investigated the dynamic expression of C5aR and C5L2 on neutrophits and their effects on neutrophil function. We found that sepsis patients displayed low expression levels of C5aR and C5L2 on neutrophils compared to healthy and systemic inflammatory response syndrome （SIRS） subjects, and this expression pattern was correlated with disease severity. Additionally, the expression levels of C5aR and C5L2 were associated with the survival of sepsis patients. In vitro, the addition of C5a significantly reduced C5aR and C5L2 expression levels and IL-8 production in neutrophils from sepsis patients. Those findings suggest that the reduced expression of C5aRs was associated with the functional impairment of neutrophils and a poor prognosis for sepsis patients. Overall, these findings may help establish C5aRs expression levels as early markers to predict the severity of sepsis.

关键词： complement 5a complement 5a receptor neutrophil prognosis sepsis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

“双支柱”调控在不同经济金融周期下的金融稳定效应:跨国实证研究

引用

国际金融研究 2024年第10期 3-14页

作者：马勇章洪铭黄辉煌中国人民大学财政金融学院中国人民大学中国财政金融政策研究中心

国内宏观经济需求不振,金融体系面临风险压力,外部环境动荡不安,这些都对“双支柱”调控框架下的政策选择提出了更高要求,分析并提炼其他经济体实施“双支柱”调控政策的有效经验,对我国具有重要的借鉴价值。本文基于84个主要经济体1998... 详细信息

国内宏观经济需求不振,金融体系面临风险压力,外部环境动荡不安,这些都对“双支柱”调控框架下的政策选择提出了更高要求,分析并提炼其他经济体实施“双支柱”调控政策的有效经验,对我国具有重要的借鉴价值。本文基于84个主要经济体1998—2020年的面板数据,系统考察了“双支柱”政策在不同经济和金融周期阶段的金融稳定效应。实证结果显示:第一,货币政策与宏观审慎政策均能较好地对信贷增速、实体部门杠杆和资产市场进行调节,并在稳定信贷和实体部门杠杆方面产生“1+1>2”的协同效应。第二,“双支柱”调控在不同的经济和金融周期阶段表现出不同的政策效果。其中,货币政策在经济衰退期的金融稳定效应要强于非衰退期,而宏观审慎政策在经济繁荣期的金融稳定效应要弱于非繁荣期;货币政策在金融繁荣期的金融稳定能力较强,而宏观审慎政策则在金融衰退期的金融稳定能力较强。第三,发达经济体的“双支柱”政策大多有效且能灵活选择,而新兴经济体的“双支柱”政策受制于宏观审慎政策有效性相对不足,导致其整体调控表现要弱于发达经济体。第四,当经济周期与金融周期同步时,货币政策的金融稳定效应会被显著削弱,而当经济周期和金融周期错位时,货币政策的金融稳定效应会被显著增强。本文的研究结论表明,“双支柱”调控在实践中需要考虑调控对象所处的经济和金融周期阶段,并根据调控的具体目标选择合适的工具或工具组合。

关键词： “双支柱”调控经济周期金融周期金融稳定

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

原发性胆汁性肝硬化50例临床分析

引用

解放军医学杂志 2007年第5期32卷 533-535页

作者：李冰陈国凤黄辉煌解放军第302医院感染7科北京100039

目的对50例原发性胆汁性肝硬化(PBC)患者的临床特征及病理特点进行回顾性研究,以提高对该病的认识。方法对临床/病理确诊为PBC患者的临床特征、各项生化指标和组织学特点进行总结。结果50例PBC患者中女性占88%(44/50),确诊时平均年龄44.... 详细信息

目的对50例原发性胆汁性肝硬化(PBC)患者的临床特征及病理特点进行回顾性研究,以提高对该病的认识。方法对临床/病理确诊为PBC患者的临床特征、各项生化指标和组织学特点进行总结。结果50例PBC患者中女性占88%(44/50),确诊时平均年龄44.9岁。最常见的临床症状为乏力(68%,34/50),其次为纳差(48%,24/50)、瘙痒(26%,13/50),最主要的体征包括黄疸(64%,32/50)、脾大(48%,24/50)、肝掌(28%,14/50)。患者血清碱性磷酸酶(ALP)、γ-谷氨酰转肽酶(γ-GT)明显升高,但随着病程逐渐发展,这2项指标逐渐下降,到晚期下降明显。32例患者(64%)胆红素有不同程度的升高,大部分患者丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)表现为轻-中度升高。41例患者(80.2%)抗线粒体抗体(AMA)/AMA-M2亚型抗体阳性。共有32例患者行肝脏穿刺病理检查,其中87.5%为早期(Ⅰ、Ⅱ期),12.5%为晚期(Ⅲ、Ⅳ期)。结论PBC主要累及中老年女性,主要表现为乏力、纳差、瘙痒,早期血清ALP和γ-GT水平升高,AMA及AMA-M2亚型抗体阳性。PBC应尽早明确诊断并及时治疗。

关键词：肝硬化,胆汁性抗线粒体抗体原发性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于多源时空数据的道路骑行适宜性评估

引用

城市建筑 2024年第9期21卷 1-4页

作者：黄辉煌武汉大学测绘遥感信息工程国家重点实验室

城市骑行系统是构建高品质人居环境的重要组成部分。构建道路骑行适宜性评估体系对改善骑行环境、提升城市管理水平有重要意义。本研究基于厦门岛内共享单车轨迹等多源时空数据,结合轨迹挖掘、深度学习和机器学习等技术挖掘道路骑行适... 详细信息

城市骑行系统是构建高品质人居环境的重要组成部分。构建道路骑行适宜性评估体系对改善骑行环境、提升城市管理水平有重要意义。本研究基于厦门岛内共享单车轨迹等多源时空数据,结合轨迹挖掘、深度学习和机器学习等技术挖掘道路骑行适宜性指标,采用层次分析法和模糊综合评价法构建城市骑行系统的评估体系。研究发现,道路骑行适宜性受路段自然环境、交通情况影响明显。浮动车定位点数、是否有自行车道和天空率等指标对道路骑行适宜性有显著影响。研究成果可为进一步优化厦门岛内骑行系统提供参考。

关键词：道路评估共享单车时空数据骑行

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

天然高纯MgO-CaO材料的活化烧结

引用

金属学报 1986年第1期22卷 132-140页

作者：张治平黄辉煌李广平冶金工业部洛阳耐火材料研究所

本工作在前文的基础上进一步研究整个MgO-CaO系列材料的活化烧结规律,着重探讨MgO/CaO之比对轻烧-水化试样烧结行为的影响和烧结试样的抗水化性。试验工作证明,天然高纯MgO-CaO系列的两相材料,用轻烧-水化方法,可以在1400℃烧后基本完... 详细信息

本工作在前文的基础上进一步研究整个MgO-CaO系列材料的活化烧结规律,着重探讨MgO/CaO之比对轻烧-水化试样烧结行为的影响和烧结试样的抗水化性。试验工作证明,天然高纯MgO-CaO系列的两相材料,用轻烧-水化方法,可以在1400℃烧后基本完成致密化过程,在1600℃烧后可得显微结构良好和高度直接结合的MgO-CaO熟料。二端员原料烧结时,晶粒异常长大,密度低,闭气孔率高。轻烧-水化试样的易烧结主要同CaO和MgO对OH-的吸附-脱附作用有关。

关键词： CaO 体积密度轻烧焙烧活化烧结 MgO-CaO 抗水化性表观气孔率显气孔率显微结构烧结速率镁白云石天然

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：