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Particuology 2024年第8期91卷 291-302页

作者： Xiaoyu Li Bowei Zhang huibo wang Hui Jin State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong UniversityXi'an710049China

The complex physical properties of supercritical water(SCW)make the heat transfer characteristics of particles within a particle cluster *** heat transfer characteristics of single particle within a particle cluster in SCW,influenced by surrounding particles,have not been effectively *** numerical simulations were conducted to investigate the heat transfer characteristics of particle clusters in SCW under different *** results were compared and analyzed with those from constant property *** was found that Reynolds number(Re)and the void fraction of particle cluster have no special effects on the variation trends of Nusselt number(Nu)for the focused ***,the particle temperature had a significant effect on the variation trends of *** effect of Re on the heat transfer rate exponent(η)of the focused particle can be divided into two zones:a significant effect zone and a non-significant effect *** effect of void fraction onηin the non-significant effect zone was *** the non-significant effect zone,ηdecreased with the increasing particle *** the significant effect zone,the variation trends ofηbecame more *** fundamental reason for this series of phenomena is the changes in distribution of physical properties.A model forηwas developed for the non-significant effect *** model can filter out the effects of Re and certain particle cluster spatial configurations,and it demonstrates good predictive performance.

关键词： Supercritical water Particle cluster Heat transfer characteristics Heat transfer rate exponent Physical properties correction

土地利用和水环境因子对大型底栖动物次级生产力的影响:以东北地区连环湖为例

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湖泊科学 2024年第3期36卷 846-857页

作者：窦乾明都雪王乐宋聃赵晨黄晓丽王慧博霍堂斌中国水产科学研究院黑龙江水产研究所寒地水域水生生物保护与生态修复重点实验室哈尔滨150070 中国科学院水生生物研究所淡水生态与生物技术国家重点实验室武汉430072 黑龙江流域渔业生态省野外科学观测研究站哈尔滨150070 农业农村部黑龙江流域渔业生态环境监测中心哈尔滨150070

土地利用和水环境因子是影响湖泊生态系统的关键因素,探究大型底栖动物次级生产力受环境因子的作用机制,可揭示底栖动物栖息地的生态系统与外源环境的关系。为了解土地利用和水环境因子对大型底栖动物次级生产力的影响,2020年对连环湖1... 详细信息

土地利用和水环境因子是影响湖泊生态系统的关键因素,探究大型底栖动物次级生产力受环境因子的作用机制,可揭示底栖动物栖息地的生态系统与外源环境的关系。为了解土地利用和水环境因子对大型底栖动物次级生产力的影响,2020年对连环湖13个主要湖泊的土地利用类型及6、8和10月的大型底栖动物、水环境因子进行调查,共采集到大型底栖动物75种,隶属于3门32科56属,其中优势种属及重要种属以摇蚊幼虫和腹足纲为主,前突摇蚊(Procladius sp.)为第一优势种。主成分分析表明,土地利用及水环境因子具备明显的时空梯度,而大型底栖动物次级生产力也存在明显的时空变化。春季、夏季、秋季次级生产力和P/B值分别为5.65、6.06、4.31 g/(m^(2)·a)和2.74、2.55、2.40 a-1,其中春季次级生产力集中于东北部湖区,龙虎泡集中于湖心区;夏季次级生产力逐渐向各湖区扩散,龙虎泡整体偏低;秋季次级生产力集中于西北部及东南部湖区,龙虎泡集中于东北部湖区。P/B值随季节的推移呈现由东部湖区向西部湖区逐渐递增的趋势,而龙虎泡始终集中于南部湖区。次级生产力和P/B值的结构分析表明,春季次级生产力主要由腹足纲构成,进入夏、秋季后以双壳纲对次级生产力的贡献最高。其中腹足纲、双壳纲、摇蚊幼虫和寡毛纲次级生产力主要集中于北部湖区、东南部湖区、中部湖区和龙虎泡,而甲壳纲仅出现于阿木塔泡。寡毛纲和双壳纲P/B值随季节的推移逐渐降低,摇蚊幼虫和腹足纲P/B值呈先升后降的趋势。通径分析表明,pH、人造地表和叶绿素a是影响年均大型底栖动物次级生产力的关键环境因子。典范对应分析表明,总磷和电导率是影响不同季节大型底栖动物次级生产力的重要环境变量。耕地、人造地表与总磷、电导率和悬浮物呈显著正相关,农业生产和城镇建设的增加是连环湖呈富营养化状态的重要原因,且此现象已对大型底栖动物次级生产力形成威胁。未来应通过控制农业面源污染、秸秆腐熟还田、鼓励粪便施肥、科学规划用地等措施改善连环湖流域的生态环境,以促进大型底栖动物资源合理的开发利用。

关键词：连环湖富营养化次级生产力无脊椎动物人类活动

Effects of physical properties of supercritical water on coarse graining of particle cluster

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Particuology 2023年第11期82卷 166-178页

作者： Xiaoyu Li huibo wang Yi Li Hui Jin State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong UniversityXi'an710049China

The coarse graining of particle cluster is of great significance to the study of a fluidized bed. The effects of variations in the physical properties of supercritical water on the coarse graining of particle cluster are investigated in this work. The drag coefficient distributions of the particle cluster are not influenced by the physical properties. However, the physical properties have effects on the values of drag coefficient. The effects of physical properties are weaker in the case of large particle concentrations. Furthermore, the physical properties lead to that the effect of particle cluster wake on the drag of downstream particles being significantly different from that of constant property flow. The variation trend of drag of coarse graining particle is consistent with that of isolated particle. The physical properties lead to significant differences in the values of drag. In this paper, the dominance of the effects of physical properties in a variety of cases is confirmed. Finally, a physical properties effect model is developed accordingly.

关键词： Supercritical water Variations in physical properties Fluidized bed Coarse grain method Particle drag

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泥岩生物气有利储层的识别及含气性评价

测井技术 2024年第2期48卷 240-247页

作者：王忠东张笑维王慧博中国石油集团测井有限公司辽河分公司辽宁盘锦124011 中国石油集团测井有限公司地质研究院陕西西安710077 中国石油天然气集团有限公司测井重点实验室陕西西安710077

随着开发的不断深入,研究区SH地区作为非主力层的第四系泥岩生物气田已经成为油田增储上产的重要勘探开发目标。这类储层由于岩性颗粒细小、泥质含量高、厚度小、成岩性差、孔隙结构复杂、非均质性强,导致储层与非储层的测井响应对比度... 详细信息

随着开发的不断深入,研究区SH地区作为非主力层的第四系泥岩生物气田已经成为油田增储上产的重要勘探开发目标。这类储层由于岩性颗粒细小、泥质含量高、厚度小、成岩性差、孔隙结构复杂、非均质性强,导致储层与非储层的测井响应对比度低、有利储层识别困难。同时,高地层水矿化度及富集黄铁矿造成储层流体识别评价困难。利用自然伽马、中子等常规测井曲线,构建含砂指数F_(SD)来表征储层含砂特征,计算泥质含量,识别划分有利储层。利用三孔隙度曲线差值比值法、合成声波时差差值法以及改进的中子-声波时差交会含气指示法等多种方法综合识别储层的含气性。在试气、生产数据刻度下,利用构建的储层含气指数FGAS建立储层含气饱和度计算模型。多种方法综合应用,效果良好,为泥岩生物气的测井精细综合评价提供了技术支撑。

关键词：泥岩生物气测井响应储层识别含砂指数含气指示

2018—2022年北京市某区腹泻病例中致泻性大肠埃希菌的感染和分子分型特征分析

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中国食品卫生杂志 2024年第6期36卷 729-734页

作者：张爽王安娜付奎元王园园李颖李辉张建涛王会波王丽丽北京市顺义区疾病预防控制中心北京101300 包头市昆都仑区疾病预防控制中心内蒙古包头014010 北京市疾病预防控制中心北京100013

目的了解北京市某区腹泻病例中致泻性大肠埃希菌(DEC)的感染情况和分子分型特征,为进一步防控工作提供依据。方法2018—2022年从北京市某区3家监测哨点医院采集1600例腹泻病例粪便标本,分离标本中的DEC;采用多重PCR技术检测其毒力基因... 详细信息

目的了解北京市某区腹泻病例中致泻性大肠埃希菌(DEC)的感染情况和分子分型特征,为进一步防控工作提供依据。方法2018—2022年从北京市某区3家监测哨点医院采集1600例腹泻病例粪便标本,分离标本中的DEC;采用多重PCR技术检测其毒力基因得到致病型,结合流行病学和临床资料进行分析。同时应用脉冲电场凝胶电泳(PFGE)技术得到分子分型,并将ETEC、EPEC和EAEC型菌株图谱作聚类分析。结果2018—2022年北京市某区1600份标本中有144份标本分离到DEC,检出率为9.00%(144/1600)。菌株致病型以ETEC为主,其次依次为EPEC、EAEC、EHEC,未检出EIEC。DEC感染病例男女比例为1.48∶1,31~45岁年龄组的DEC检出率最高(11.15%,59/529)。DEC阳性检出率最高的年份为2019年,各年夏季检出率均最高。DEC在不同年龄组和年份中的阳性检出率均有显著差异。DEC阳性病例症状以腹泻、脱水、腹痛为主,且多为水样便。144株DEC分为111条带型,同源性13.07%~100.00%。同带型的菌株数目2~7条,分离时间间隔从当天到几年不等。结论本区DEC致病型以ETEC和EPEC为主,且存在EHEC感染;夏季高发,青壮年中检出较多;PFGE条带呈高度多态性分布。

关键词：致泻性大肠埃希菌腹泻感染分子分型食源性致病菌

血清AIF-1、Bmi-1、MAP19联合诊断宫颈癌的价值分析

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疑难病杂志 2024年第8期23卷 971-975页

作者：王汇博陈慧君朱敏武汉大学中南医院妇产科武汉430071 武汉大学中南医院检验科武汉430071

目的探究宫颈癌患者血清中同种异体移植物炎性因子1(AIF-1)、B细胞特异性莫洛尼白血病毒插入位点1(Bmi-1)、甘露聚糖结合凝集素相关蛋白19(MAP19)水平变化及对宫颈癌患者的诊断价值。方法选取2023年1—12月武汉大学中南医院妇产科收治... 详细信息

目的探究宫颈癌患者血清中同种异体移植物炎性因子1(AIF-1)、B细胞特异性莫洛尼白血病毒插入位点1(Bmi-1)、甘露聚糖结合凝集素相关蛋白19(MAP19)水平变化及对宫颈癌患者的诊断价值。方法选取2023年1—12月武汉大学中南医院妇产科收治宫颈癌患者180例为观察组,另选取同期健康体检者180例为健康对照组。采用酶联免疫吸附法(ELISA)检测2组研究对象血清AIF-1、Bmi-1、MAP19水平;比较宫颈癌不同分期患者血清中AIF-1、Bmi-1、MAP19水平;绘制受试者工作特征(ROC)曲线分析血清AIF-1、Bmi-1、MAP19水平对宫颈癌的诊断价值。结果与健康对照组比较,观察组患者血清AIF-1、Bmi-1、MAP19水平上升(t=13.054、13.598、10.601,P均<0.001);不同分期宫颈癌患者血清中AIF-1、Bmi-1、MAP19水平随分期升高而升高(F=32.001、8.232、10.602,P均<0.001);宫颈癌患者血清AIF-1、Bmi-1、MAP19高水平在病理低分化、HPV阳性、FIGOⅢ~Ⅳ期和淋巴结转移中比例升高(AIF-1:χ^(2)=41.162、27.607、13.718、23.824,P均<0.001;Bmi-1:χ^(2)=33.563、22.060、22.599、18.451,P均<0.001;MAP19:χ^(2)=49.585、14.913、25.545、13.605,P均<0.001);血清AIF-1、Bmi-1、MAP19水平及三者联合预测宫颈癌病变的AUC分别为0.759、0.726、0.751、0.839,三者联合优于各自单独预测价值(Z=2.499、3.363、2.749,P=0.012、<0.001、0.016)。结论宫颈癌患者血清AIF-1、Bmi-1、MAP19水平显著上升,且随宫颈癌分期升高而升高,三者联合对宫颈癌具有较高的诊断效能。

关键词：宫颈癌同种异体移植物炎性因子1 B细胞特异性莫洛尼白血病毒插入位点1 甘露聚糖结合凝集素相关蛋白19 诊断

Biocompatible carbon dots with low-saturation-intensity and highphotobleaching-resistance for STED nanoscopy imaging of the nucleolus and tunneling nanotubes in living cells

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Nano Research 2019年第12期12卷 3075-3084页

作者： Hao Li Shuai Ye Jiaqing Guo huibo wang Wei Yan Jun Song Junie Qu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College cf Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices Institute of Functional Nano and Soft Materials(FUNSOM)Soochow UniversitySuzhou 215123China

Many kinds of nano particles and organic dyes as fluorescent probes have been used in the stimulated emission depletion(STED)*** to high toxicity,photobleaching and non-water solubility,these fluorescent probes are hard to apply in living cell ***,we reporta new fluorescence carbon dots(FNCDs)with high photoluminescence quantum yield(56%),low toxicity,anti-photobleaching and goodwater-solubility that suitable for live-cell imaging can be obtained by doping fluorine ***,the FNCDs can stain the nucleolusand tunneling nanotubes(TNTs)in the living *** importantly,for STED nanoscopy imaging,the FNCDs effectively depleted backgroundsignals and improved imaging ***,the lateral resolution of single FNCDs size under the STED nanoscopy is up to 22.1 nm for FNCDs deposited on a glass slide was *** because of their good water dispersibility,the higher resolution of single FNCDs sizein the nucleolus of a living cell can be up to 19.7 *** the image optimizati on steps,the fine fluoresce nee images of TNTs diameter with ca.75 nm resolution is obtained living cell,yielding a threefold enhancement compared with that in confocal ***,the FNCDs show excellent photobleaching resistance after 1,000 scan cycles in the STED *** results show that FNCDs have significant potentialfor application in STED nanoscopy.

关键词： carbon dots excellent photobleaching resistance high resolution stimulated emission depletion(STED)nanoscopy tunneling nanotubes

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罗沙司他治疗心血管疾病的最新进展

中国动脉硬化杂志 2024年第5期32卷 456-460页

作者：鲍炜吕云波王辉波胡婷三峡大学人民医院心血管内科湖北省宜昌市443000

心血管疾病目前仍然是导致死亡率较高的疾病之一,当前防治心血管疾病的药物可以明显改善症状,但在降低死亡率方面仍有不足,所以需要既能改善症状,又能减少死亡率的新型药物。罗沙司他作为一种脯氨酸羟化酶抑制剂,通过调控缺氧诱导因子(H... 详细信息

心血管疾病目前仍然是导致死亡率较高的疾病之一,当前防治心血管疾病的药物可以明显改善症状,但在降低死亡率方面仍有不足,所以需要既能改善症状,又能减少死亡率的新型药物。罗沙司他作为一种脯氨酸羟化酶抑制剂,通过调控缺氧诱导因子(HIF)的表达,可以有效改善患者缺氧症状,从而延长生存时间。HIF几乎参与机体所有发育、病理或生理的过程,包括促红细胞生成素的生成、铁吸收代谢、细胞分化、能量代谢、炎症和免疫调节等过程。目前该药在治疗肾性贫血方面有很好的前景,但在心血管疾病方面应用还较少。该文系统、全面地探讨了罗沙司他在心血管疾病中的作用,以期为心血管疾病的治疗提供一定帮助。

关键词：罗沙司他心血管疾病缺氧诱导因子脯氨酸羟化酶

Realizing the highly reversible Zn^(2+)and Na^(+) dual ions storage in high-crystallinity nickel hexacyanoferrate microcubes for aqueous zinc-ion batteries

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Journal of Materials Science & Technology 2023年第33期164卷 102-110页

作者： Kexuan wang Zhu Xu Heng Li huibo wang Mingzheng Ge Jilei Liu Shengwen Li Zekun Hu Mengyu Zhu Yanyan Zhang Yuxin Tang Shi Chen Institute of Applied Physics and Materials Engineering University of MacaoMacao SAR 999078China State Key Laboratory of High-Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology of Clean EnergyHunan Province Key Laboratory for Advanced Carbon Materials and Applied TechnologyHunan UniversityChangsha 410082China College of Chemical Engineering Fuzhou UniversityFuzhou 350116China

Prussian blue analogues(PBAs)with the 3D open framework are regarded as promising cathode candidates for aqueous Zinc ion batteries(ZIBs).Among various PBAs,nickel hexacyanoferrate(NiHCF)has attracted considerable attention because of its high operating voltage and economic ***,the cyclability of NiHCF is unsatisfactory due to poor structural stability during Zn^(2+) ions insertion/***,the ion storage mechanism of NiHCF in aqueous electrolytes has not been fully revealed ***,high-crystallinity NiHCF(HC-NiHCF)microcubes with improved structural stability and larger crystal plane spacing are *** the first time,highly reversible Zn2+ions and Na+ions co-insertion/extraction are achieved for the HC-NiHCF microcubes in mixed aqueous electrolyte,as evidenced by various observations including two separated discharge plateaus and sequential changes of Na 1s and Zn 2p signals in ex-situ X-ray photoelectron spectroscopy(XPS).As a result,a high specific capacity of 73.9 mAh g^(−1) is obtained for the HC-NiHCF microcubes at 0.1 A g−1,combined with enhanced cycle stability(75%vs.16.4%)over 1000 cycles at 2 A g^(−1).The reversible Zn^(2+) ions and Na+ions co-insertion in HC-NiHCF microcubes reveals a new ion storage mechanism of Ni-based PBAs in aqueous electrolytes.

关键词： Aqueous zinc-ion batteries Prussian blue analogues Ion storage mechanism Dual ions storage High crystallinity

Nature-inspired materials and designs for flexible lithium-ion batteries

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Carbon Energy 2022年第5期4卷 878-900页

作者： Heng Li huibo wang Dan Chan Zhu Xu Kexuan wang Mingzheng Ge Yanyan Zhang Shi Chen Yuxin Tang State Key Laboratory of High-Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghaiChina Institute of Applied Physics and Materials Engineering University of MacaoMacao SARChina College of Chemical Engineering Fuzhou UniversityFuzhouChina School of Textile and Clothing Nantong UniversityNantongChina

Flexible lithium-ion batteries(FLBs)are of critical importance to the seamless power supply of flexible and wearable electronic ***,the simultaneous acquirements of mechanical deformability and high energy density remain a major challenge for *** billions of years of evolutions,many plants and animals have developed unique compositional and structural characteristics,which enable them to have both high mechanical deformability and robustness to cope with the complex and stressful *** by nature,many new materials and designs emerge recently to achieve mechanically flexible and high storage capacity of lithiumion batteries at the same ***,we summarize these novel FLBs inspired by natural and biological materials and *** first give a brief introduction to the fundamentals and challenges of ***,we highlight the latest achievements based on nature inspiration,including fiber-shaped FLBs,origami and kirigami-derived FLBs,and the nature-inspired structural designs in ***,we discuss the current status,remaining challenges,and future opportunities for the development of *** concise yet focused review highlights current inspirations in FLBs and wishes to broaden our view of FLB materials and designs,which can be directly“borrowed”from nature.

关键词： bioinspired materials flexibility lithium-ion batteries structural design