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基于Web的异常数据检测系统设计与实现

现代计算机 2024年第4期30卷 88-93页

作者：常鑫田立勤华北科技学院计算机学院廊坊065201

针对大数据处理中数据来源复杂,且在清洗过程中存在较多相似的问题,开发了一款异常数据检测系统。系统使用流行的Python编程语言和轻量级的FlaskWeb框架,能够简化数据处理工作中的重复流程,极大减轻数据分析的工作量,提高工作效率,利用... 详细信息

针对大数据处理中数据来源复杂,且在清洗过程中存在较多相似的问题,开发了一款异常数据检测系统。系统使用流行的Python编程语言和轻量级的FlaskWeb框架,能够简化数据处理工作中的重复流程,极大减轻数据分析的工作量,提高工作效率,利用系统内置的异常检测算法和用户上传的自定义算法完成对数据中异常的检测工作。

关键词： Web Python Flask 异常检测

Momentum-space crystal in narrow-line cooling of ^(87)Sr

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Chinese Physics B 2019年第1期28卷 360-366页

作者： Jian-Xin Han Ben-Quan Lu Mo-Juan Yin Ye-Bing Wang Qin-Fang Xu Xiao-Tong Lu hong chang Key Laboratory of Time and Frequency Primary Standards National Time Service Center Chinese Academy of Sciences University of Chinese Academy of Sciences

The discovery of the momentum space crystal based on the alkaline-earth atom ^(88)Sr in narrow-line cooling has paved the way to explore this novel physical phenomenon in other cold atom systems. In this paper, a momentum space crystal based on the fermions ^(87)Sr in narrow-line cooling of transition^1S_0–~3P_1 is demonstrated. We theoretically analyze and compare the formation principle of the narrow-line with that of broad-line cooling, and achieve the momentum space crystal in experiment. Beyond that we present a series of numerical calculations of those important parameters which influence the distribution and size of the momentum space crystal. Correspondingly, we vary the values of these parameters in experiment to observe the momentum space crystal evolution and distribution. The experimental results are in conformity with the results of the theoretically numerical calculations. These results and analyses provide a detailed supplementary study on the formation and evolution of momentum space crystal. In addition, this work could also give a guideline on atomic manipulation by narrow-line cooling.

关键词： momentum space crystal narrow-line cooling strontium

Identification of TRPM7 channels in human intestinal interstitial cells of Cajal

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World Journal of Gastroenterology 2009年第46期15卷 5799-5804页

作者： Byung Joo Kim Kyu Joo Park Hyung Woo Kim Seok Choi Jae Yeoul Jun In Youb chang Ju-hong Jeon Insuk So Seon Jeong Kim School of Korean Medicine Pusan National University Department of Surgery College of MedicineSeoul National University Department of Physiology College of MedicineChosun University Department of Anatomy College of MedicineChosun University Center for Bio-Artif icial Muscle and Department of Physiology College of MedicineSeoul National University Center for Bio-Artifi cial Muscle and Depart-ment of Biomedical Engineering Hanyang University

AIM： To investigate the characteristics of slow electrical waves and the presence of transient receptor potential melastatin-type 7 （TRPM7） in the human gastrointestinal （GI） tract. METHODS： Conventional microelectrode techniques were used to record intracellular electrical responses from human GI smooth muscle tissue. Immunohistochemistry was used to identify TRPM7 channels in interstitial cells of Cajat （ICCs）. RESULTS： The human GI tract generated slow electrical waves and had ICCs which functioned as pacemak er cells. Flufenamic acid, a nonselective cation channel blocker, and 2-APB （2-aminoethoxydiphenyl borate） and La3＋, TRPM7 channel blockers, inhibited the slowwaves. Also, TRPM7 channels were expressed in ICCs in human tissue. CONCLUSION： These results suggest that the human GI tract generates slow waves and that TRPM7 channels expressed in the ICCs may be involved in the gen- eration of the slow waves.

关键词： Electrophysiology Interstitial cells of Cajal TRPM cation channels Transient receptor potential melastatin-type 7 protein Human Gastrointestinal tract

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一种复非线性系统的动力学特性和同步分析

控制理论与应用 2012年第9期29卷 1181-1185页

作者：琚宏昌李红远广西工学院鹿山学院土木工程系广西柳州545616

本文介绍一种新复非线性系统并研究它的动力学特性(包括不变量、耗散度、平衡和稳定性、Lyapunov指数、混沌行为、混沌吸引子),以及该系统产生混沌的必要条件,发现在一定参数条件下,系统存在2个或4个螺线形混沌吸引子,通过研究驱动系统... 详细信息

本文介绍一种新复非线性系统并研究它的动力学特性(包括不变量、耗散度、平衡和稳定性、Lyapunov指数、混沌行为、混沌吸引子),以及该系统产生混沌的必要条件,发现在一定参数条件下,系统存在2个或4个螺线形混沌吸引子,通过研究驱动系统和响应系统的关系,导出了混沌同步的控制函数显式表达式.Lyapunov函数分析证明,系统误差是渐近稳定的,控制函数可以使主动系统和响应系统完全同步.

关键词：混沌吸引子同步主动控制平衡和稳定性

Phylogenomic Insights into Deep Phylogeny of Angiosperms Based on Broad Nuclear Gene Sampling

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Plant Communications 2020年第2期1卷 77-87页

作者： Lingxiao Yang Danyan Su Xin chang Charles SPFoster Linhua Sun Chien-Hsun Huang Xiaofan Zhou Liping Zeng hong Ma Bojian Zhong College of Life Sciences Nanjing Normal UniversityNanjingChina School of Life and Environmental Sciences University of SydneySydneyAustralia Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijingChina State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological EngineeringSchool of Life SciencesFudan UniversityShanghaiChina Guangdong Province Key Laboratory of Microbial Signals and Disease Control Integrative Microbiology Research CentreSouth China Agricultural UniversityGuangzhouChina Institute for Integrative Genome Biology and Department of Botany and Plant Sciences University of CaliforniaRiversideCAUSA Department of Biology Huck Institutes of the Life SciencesPennsylvania State UniversityUniversity ParkPAUSA

Angiosperms(flowering plants)are the most diverse and species-rich group of *** vast majority(99.95%)of angiosperms form a clade called Mesangiospermae,which is subdivided into five major groups:eudicots,monocots,magnoliids,Chloranthales,and *** relationships among these Mesangiospermae groups have been the subject of long *** this study,we assembled a phylogenomic dataset of 1594 genes from 151 angiosperm taxa,including representatives of all five lineages,to investigate the phylogeny of major angiosperm lineages under both coalescent-and concatenationbased *** dissected the phylogenetic signal and found that more than half of the genes lack phylogenetic information for the backbone of angiosperm *** further removed the genes with weak phylogenetic signal and showed that eudicots,Ceratophyllales,and Chloranthales form a clade,with magnoliids and monocots being the next successive sister *** frequencies of gene tree conflict are suggestive of incomplete lineage sorting along the backbone of the angiosperm *** analyses suggest that a fully bifurcating species tree may not be the best way to represent the early radiation of ***,we inferred that the crown-group angiosperms originated approximately between 255.1 and 222.2 million years ago,and Mesangiospermae diversified into the five extant groups in a short time span(27 million years)at the Early to Late Jurassic.

关键词： Mesangiospermae gene tree conflict phylogenomics phylogenetic signal divergence times

全面抗战时期党在灾荒防治工作中的社会动员——以两大红色报刊相关报道为中心的考察

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郑州航空工业管理学院学报（社会科学版） 2024年第2期43卷 12-20页

作者：武艳敏李畅郑州大学马克思主义学院河南郑州450001

社会动员是党在全面抗战时期开展灾荒防治工作时所使用的重要方法,在生产备荒和灾后救济等环节发挥了巨大的作用。党和政府创造性地运用了组织动员、示范动员、竞争动员和资源动员等动员方式,发动根据地的男女老幼参与开荒耕种、灭蝗、... 详细信息

社会动员是党在全面抗战时期开展灾荒防治工作时所使用的重要方法,在生产备荒和灾后救济等环节发挥了巨大的作用。党和政府创造性地运用了组织动员、示范动员、竞争动员和资源动员等动员方式,发动根据地的男女老幼参与开荒耕种、灭蝗、兴修水利、抢种抢收和手工业副业生产等一系列灾荒防治工作。党和政府的社会动员工作不仅保障了根据地的生产、预防了灾荒发生、减轻了灾荒的破坏,同时也在社会上起到了移风易俗的作用,在精神和物质的双重意义上促进了革命事业的发展,为抗日战争的胜利做出了贡献。

关键词：中国共产党全面抗战时期社会动员防治灾荒红色报刊

Dynamin like protein 1 participated in the hemoglobin uptake pathway of Plasmodium falciparum

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Chinese Medical Journal 2009年第14期122卷 1686-1691页

作者： ZHOU hong-chang GAO Yu-hui Zhong Xiang WANG Heng Department of Microbiology and Parasitology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College 5# Dong Dan San Tiao Rm. 522 Beijing 100005 China

Background During the blood stage of malaria infection, parasites internalize in the host red blood cells and degrade massive amounts of hemoglobin for their development. Although the morphology of the parasite＇s hemoglobin uptake pathway has been clearly observed, little has been known about its molecular mechanisms. Methods The recombinant proteins from Plasmodium falciparum, dynamin like protein 1 （PfDYN1） and 2 （PfDYN2） GTPase domain, were expressed in E .coil and showed GTPase activity. By using a dynamin inhibitor, dynasore, we demonstrated the involvement of PfDYN1 in the hemoglobin uptake pathway. Results The GTPase activity of the two recombinant proteins was inhibited by dynasore in vitro. Treatment of parasite cultures with 80 μmol/L dynasore at the ring and early trophozoite stage resulted in substantial inhibition of parasite growth and in an obvious decline of hemoglobin quantum. Furthermore, reduced intracellular hemozoin accumulation and decreased uptake of the FITC-dextran were also observed, together with distinctive changes in the ultrastructure of parasites after the dynasore treatment. Conclusions Our results show that PfDYN1 plays an important role in the hemoglobin uptake pathway of P. falciparum and suggest its possibility of being a novel target for malaria chemotherapy.

关键词： Plasmodium falciparum hemoglobin uptake dynamin inhibitor

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复杂MeSO_4体系初步除杂和深度净化

过程工程学报 2006年第6期6卷 894-898页

作者：彭长宏唐谟堂黄虹中南大学冶金科学与工程学院湖南长沙410083

分别以浸出液和氟化沉淀液为原料，采用单因素法对复杂MeSO4体系氟化沉淀除钙镁和复盐沉淀深度净化进行了研究．氟化沉淀除钙镁实验结果表明，在温度90℃、时间1．0h、pH3．5及NH4F用量为理论量2．0倍的优化条件下，Ca^2＋和Mg^2＋的平... 详细信息

分别以浸出液和氟化沉淀液为原料，采用单因素法对复杂MeSO4体系氟化沉淀除钙镁和复盐沉淀深度净化进行了研究．氟化沉淀除钙镁实验结果表明，在温度90℃、时间1．0h、pH3．5及NH4F用量为理论量2．0倍的优化条件下，Ca^2＋和Mg^2＋的平均去除率分别为92．98％和89．95％，复盐沉淀深度净化实验结果表明，硫酸铵的浓度和溶液酸度是复盐沉淀深度除Si的关键，优化条件为pH=1．5～2．5、游离硫酸铵浓度2．0～2．5mol／L、时间1．0～1.5h和室温．在此条件下，Fe，Mn和Zn三种主体成分的沉淀率分别是69．94％，86．52％和96．88％，Si的去除率为54．85％．

关键词：氟化沉淀复盐沉淀深度净化

Role of Toll-like receptors in regulatory functions of T and B cells

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Chinese Science Bulletin 2008年第8期53卷 1121-1127页

作者： chang ZongLiang Institute for Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai 200031 China

Pathogens can find their ways to most sites in the host. Pathogen sensors, such as Toll-like receptors (TLRs), must be equally and broadly distributed on immune cells to combat them through innate and adaptive immunity. Most classes of TLRs are found in innate immune cells to obtain an immediate re- sponse against pathogens, but recent studies indicate that a number of TLRs are wildly expressed in T and B cells, suggesting TLRs also directly regulate adaptive immune responses. Due to the rapid in- crease of new information on the multiple roles of TLRs, in this paper we aim to review several main properties of TLRs and their direct role in T and B cells. This review consists of 6 parts: (i) Characteris- tics of Toll-like receptors (TLRs) and signaling; (ii) signalling pathways of TLRs; (iii) TLR expressions on human leukocytes; (iv) TLR expressions and functions in the Th1, CD4+CD45RO+ memory T cells and regulatory/suppressor T as well as B cell populations; (v) therapeutic potential of TLR agonists; (Vi) discussion and perspective. The latest findings and potential therapeutic applications are discussed. There is growing evidence supporting the concept that TLR activation contributes not only to innate immunity but also to adaptive immunity, including direct regulation of both T and B lymphocytes by TLRs.

关键词： T细胞 B细胞 TLRs 免疫能力治疗方法病原体