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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 181-185页

作者： Mitsuki tomita Takeshi Ogura Akitoshi Hakoda Saori Ueno Atsushi Okuda Nobu Nishioka Yoshitaro Yamamoto Hiroki Nishikawa 2nd Department of Internal Medicine Osaka Medical and Pharmaceutical UniversityOsakaJapan Endoscopy Center Osaka Medical and Pharmaceutical UniversityOsakaJapan

Background:To prevent stent migration during endoscopic ultrasound-guided hepaticogastrostomy(EUS-HGS),intra-scope channel release technique is important,but is unfamiliar to non-expert *** self-expandable metal stent(SEMS)is an additional factor to prevent stent ***,no compara-tive studies of laser-cut-type and braided-type during EUS-HGS have been *** aim of this study was to compare the distance between the intrahepatic bile duct and stomach wall after EUS-HGS among laser-cut-type and braided-type ***:To evaluate stent anchoring function,we measured the distance between the hepatic parenchyma and stomach wall before EUS-HGS,one day after EUS-HGS,and 7 days after ***,propensity score matching was performed to create a propensity score for using laser-cut-type group and braided-type ***:A total of 142 patients were enrolled in this *** them,24 patients underwent EUS-HGS using a laser-cut-type SEMS,and 118 patients underwent EUS-HGS using a braided-type ***-HGS using the laser-cut-type SEMS was mainly performed by non-expert endoscopists(n=21);EUS-HGS using braided-type SEMS was mainly performed by expert endoscopists(n=98).The distance after 1 day was significantly shorter in the laser-cut-type group than that in the braided-type group[2.00(1.70-3.75)vs.6.90(3.72-11.70)mm,P<0.001].In addition,this distance remained significantly shorter in the laser-cut-type group after 7 *** these results were similar after propensity score matching analysis,the distance between hepatic parenchyma and stomach after 7 days was increased by 4 mm compared with the distance after 1 day in the braided-type *** the other hand,in the laser-cut-type group,the distance after 1 day and 7 days was almost the ***:EUS-HGS using a laser-cut-type SEMS may be safe to prevent stent migration,even in non-expert hands.

关键词： Endoscopic ultrasound-guided hepaticogastrostomy Endoscopic ultrasound-guided biliary drainage Endoscopic retrograde cholangiopancreatography

Development and Evaluation of 3D Delivery Animation Software Designed to Improve the Mother’s and Spouse’s Satisfaction with Delivery

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Health 2024年第5期16卷 439-458页

作者： Ayako Sasaki Sachi Chikazawa Nojima Kumiko tomita Takako Hatakeyama Keiko Imoto Yasufumi Imoto Nobutane Faculty of Nursing Osaka Medical and Pharmaceutical University Takatsuki Japan Imoto Ladies Clinic Echizen Japan

Purpose: To clarify the effectiveness of 3-D delivery animation software for the mother’s and husband’s satisfaction with delivery. Subjects and Method: We independently developed a software application used to display the pelvic region and explain the labor process. The study involved a collaboration with hospital staff who recruited 18 primiparous and 18 multiparous mothers who were hospitalized for delivery at Facility A. The midwife explained the process of delivery using the “Delivery Animation Software”. A self-administered, anonymous questionnaire was distributed and analyzed separately for primiparous and multiparous mothers and their husbands. Results: 1) For both primiparous and multiparous couples, both mothers and their husbands gained a significantly higher level of understanding after delivery than during pregnancy. 2) The Self-Evaluation Scale for Experience of Delivery results were as follows: “I did my best for the baby even if it was painful” was selected more often for “birth coping skills”;“reliable medical staff” was selected more often for “physiological birth process”;“the birth progressed as I expected” was selected frequently by primiparous mothers;and “the birth progressed smoothly” was selected often by multiparous mothers. 3) In terms of husbands’ satisfaction with the delivery, “I was satisfied with the delivery”, “I was given an easy-to-understand explanation”, and “They explained the process to me” was selected of primiparous and multiparous fathers. 4) All primiparous and multiparous mothers positively evaluated whether the delivery animation was helpful in understanding the process of delivery. Conclusion: The delivery animation was effective in improving the understanding and satisfaction of both the mothers and their husbands.

关键词： Mother Spouse Satisfaction 3D Delivery Animation Software

Prophylactic Pattern Scanning Laser Retinal Photocoagulation for Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats: Preliminary Experimental Results

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Journal of Diabetes Mellitus 2024年第3期14卷 153-165页

作者： Rina Takagi Yoshiaki Tanaka Tetsuya Hasegawa Masami Shinohara Yasushi Kageyama Tomohiko Sasase Machiko Shimmura-tomita Akihiro Kakehashi Toshikatsu Kaburaki Department of Ophthalmology Saitama Medical Center Jichi Medical University Saitama-shi Saitama-ken Japan Tokyo Animal & Diet Department CLEA Japan Inc. Tokyo Japan Biological/Pharmacological Research Laboratories Central Pharmaceutical Research Institute Japan Tobacco Inc. Takatsuki Osaka Japan

Research Background and Purpose: The number of diabetic patients is rapidly increasing, making it crucial to find methods to prevent diabetic retinopathy (DR), a leading cause of blindness. We investigated the effects of prophylactic pattern scanning laser retinal photocoagulation on DR development in Spontaneously Diabetic Torii (SDT) fatty rats as a new prevention approach. Methods: Photocoagulation was applied to the right eyes of 8-week-old Spontaneously Diabetic Torii (SDT) fatty rats, with the left eyes serving as untreated controls. Electroretinography at 9 and 39 weeks of age and pathological examinations, including immunohistochemistry for vascular endothelial growth factor and glial fibrillary acidic protein at 24 and 40 weeks of age, were performed on both eyes. Results: There were no significant differences in amplitude and prolongation of the OP waves between the right and left eyes in SDT fatty rats at 39 weeks of age. Similarly, no significant differences in pathology and immunohistochemistry were observed between the right and left eyes in SDT fatty rats at 24 and 40 weeks of age. Conclusion: Prophylactic pattern scanning retinal laser photocoagulation did not affect the development of diabetic retinopathy in SDT fatty rats.

关键词： Diabetes Pattern Scanning Laser Diabetic Retinopathy Spontaneously Diabetic Torii Fatty Rats Electroretinography

基于一维和三维CFD方法的四级径流式鼓风机扩压器和回流器设计与优化

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风机技术 2024年第3期66卷 47-59页

作者： Vlad Goldenberg Leonid Moroz Ti-shun Zhang Shigeyuki Tomimatsu Masatoshi tomita SoftInWay Inc. USA DMWCorporation Japan

Soft In Way Inc. performed the aerodynamic design of a 4 stages high pressure radial blower with vaneless diffusers and deswirlers for DMW Corporation in 2021. The nominal pressure ratio of the machine is near *** a pressure ratio often characterizes what would typically be called a compressor, especially if the compression work is performed in one stage. For the subject machine of the present study, the compression work is split into 4 *** paper describes the design procedure for this blower, initially focusing in depth on the tradeoffs between work split,rotor diameter, and rotor vane back-sweep angle. The paper then presents a further design and optimization work of different variants of diffuser and deswirler based on aerodynamic performance for this 4 stages radial blower. The number of deswirler blades in the return channel was reduced from 19 to 10 in consideration of manufacturing requirements. To minimize losses in performance due to reduced blade number, several candidates of varied geometry shape deswirler blades were obtained from an automatic design and optimization workflow combining with 3D CFD calculation. All candidates of deswirler were implemented to the entire 4 stages radial blower to analyze machine performance by 3D CFD calculation and the best 10-blade deswirler geometry was determined. 3D CFD analysis shows that 10 blades of deswirler is unable to provide the same pressure rise and efficiency as the original design with 19 blades when all other parts of the design, such as rotor and diffuser are maintained the same. To further improve the blower performance, the similar automatic workflow was applied to study vaned diffuser influence to the blower performance based on the new blower configuration. The number and geometry of best diffuser blades was obtained from the automatic workflow and entire blower performance with vaned diffuser was analyzed and validated by 3D CFD calculation. After finalizing the aerodynamic flow path geome

关键词： Radial Blower Blower Design Blower 1D Analysis Deswirler Diffuser Automatic Optimization 3DCFD Surge Determination

A Fine-Grained Runtime Power/Performance Optimization Method for Processors with Adaptive Pipeline Depth

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Journal of Computer Science & Technology 2011年第2期26卷 292-301页

作者：姚骏 Shinobu Miwa Hajime Shimada Shinji tomita Graduate School of Information Science Nara Institute of Science and Technology School of Engineering Tokyo University of Agriculture and Technology Graduate School of Informatics Kyoto University Institute for Integrated Cell-Material Sciences Kyoto University

Recently, a method known as pipeline stage unification （PSU） has been proposed to alleviate the increasing energy consumption problem in modern microprocessors. PSU achieves a high energy efficiency by employing a changeable pipeline depth and its working scheme is eligible for a fine control method. In this paper, we propose a dynamic method to study fine-grained program interval behaviors based on some easy-to-get runtime processor metrics. Using this method to determine the proper PSU configurations during the program execution, we are able to achieve an averaged 13.5% energydelay-product （EDP） reduction for SPEC CPU2000 integer benchmarks, compared to the baseline processor. This value is only 0.14% larger than the theoretically idealized controlling. Our hardware synthesis result indicates that the proposed method can largely decrease the hardware overhead in both area and delay costs, as compared to a previous program study method which is based on working set signatures.

关键词： dynamic optimization energy saving fine-grained pipeline stage unification workload analysis

Bis(phthalocyaninato)yttrium Grown on Au(111): Electronic Structure of a Single Molecule and the Stability of Two- dimensional Films Investigated by Scanning Tunneling Microscopy/Spectroscopy at 4.8 K

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Nano Research 2010年第8期3卷 604-611页

作者： Yanfeng Zhang Pengfei Guan hironari Isshiki Mingwei Chen Masahiro Yamashita Tadahiro Komeda Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversitySendai 980-0877Japan Center for Nanochemistry Academy for Advanced Interdisciplinary StudiesDepartment of Advanced Materials and NanotechnologyCollege of EngineeringBeijing UniversityBeijing 100871China WPI-Advanced Institute for Materials Research Tohoku UniversitySendai 980-8577Japan Department of Chemistry Graduate School of ScienceTohoku UniversitySendai 980-8578Japan CREST Japan Science and Technology Agency(JST)Saitama 332-0012Japan

Scanning tunneling microscopy/spectroscopy(STM/STS)at 4.8 K has been used to examine the growth of a double-decker bis(phthalocyaninato)yttrium(YP_(c2))molecule on a reconstructed Au(111)*** differential conductance spectra(dI/dV)of a single YPc2 molecule allow the characteristics of the highest occupied molecular orbital(HOMO)and the lowest unoccupied molecular orbital(LUMO)to be ***,lateral distributions of the local density of states(LDOS)have also been obtained by dI/dV mapping and confirmed by first principles *** electronic feature mappings and theoretical calculations provide a basis for understanding the unique STM morphology of YPc2,which is usually imaged as an eight-lobed *** addition,we demonstrate that bias-dependent STM morphologies and simultaneous dI/dV maps can provide a way of understanding the stability of two-dimensional YP_(c2) films.

关键词： Scanning tunneling microscopy/spectroscopy(STM/STS) phthalocyanine electronic structure

Effective Isolation of Retrotransposons and Repetitive DNA Families from the Wheat Genome

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Journal of Integrative Plant Biology 2010年第7期52卷 679-691页

作者： Motonori tomita Munenori Asao Aya Kuraki Molecular Genetics Laboratory Faculty of AgricultureTottori University

New classes of repetitive DNA elements were effectively identified by isolating small fragments of the elements from the wheat genome. A wheat A genome library was constructed from Triticum monococcum by degenerate cleavage with EcoO1091, the recognition sites of which consisted of 5＇-PuGGNCCPy-3＇ multi-sequences. Three novel repetitive sequences pTm6, pTm69 and pTm58 derived from the A genome were screened and tested for high copy number using a blotting approach, pTm6 showed identity with integrase domains of the barley Tyl-Copia-retrotransposon BARE-1 and pTm58 showed similarity to the barley Ty3-gypsy-like retrotransposon Romani. pTm69, however, constituted a tandem array with useful genomic specificities, but did not share any identity with known repetitive elements. This study also sought to isolate wheat D-genome-specific repetitive elements regardless of the level of methylation, by genomic subtraction. Total genomic DNA of Aegilops tauschii was cleaved into short fragments with a methylation-insensitive 4 bp cutter, Mbol, and then common DNA sequences between Ae. tauschii and Triticum turgidum were subtracted by annealing with excess T. turgidum genomic DNA. The D genome repetitive sequence pAt1 was isolated and used to identify an additional novel repetitive sequence family from wheat bacterial artificial chromosomes with a size range of 1 395-1 850 bp. The methods successfully led pathfinding of two unique repetitive families.

关键词： DNA Effective Isolation of Retrotransposons and Repetitive DNA Families from the Wheat Genome AABB

Induced Charge of Spherical Dust Particle on Plasma-facing Wall in Non-uniform Electric Field

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Plasma Science and Technology 2006年第1期8卷 122-124页

作者： Y.tomita R.SMIRNOV 朱思峥 National Institute for Fusion Science 322-6 Oroshi-choToki 509-5292 Japan The Graduate University for Advanced Studies 322-6 Oroshi-choToki 509-5292 Japan Institute of Plasma Physics Chinese Academy of SciencesHefei 230031China

Induced charge of a spherical dust particle on a plasma-facing wall was investigated analytically, where non-uniform electric field was applied externally. The one-dimensional nonuniform electrostatic potential was approximated by the polynomial of the normal coordinate toward the wall. The bipolar coordinate was introduced to solve the Laplace equation of the induced electrostatic potential. The boundary condition at the dust surface determines the unknown coefficients of the general solution of the Laplace equation for the induced potential. From the obtained potential the surface induced charge can be calculated. This result allows estimating the effect of the surrounding plasma, which shields the induced charge.

关键词： dust particle induced charge non-uniform electric field

Low-velocity pneumatic conveying in horizontal pipe for coarse particles and fine powders

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Particuology 2008年第5期6卷 316-321页

作者： Yuji tomita Vijay Kumar Agarwal Hiroyuki Asou Katsuya Funatsu Kyushu Institute of Technology 1-1 SensuichoTobataKitakyushu 804-5500Japan Indian Institute of Technology Hauz KhasNew Delhi 110016India

First, the characteristics of low-velocity conveying of particles having different hardness are experimentally investigated in a horizontal pipeline in terms of flow pattern and pressure drop to show that the slug flow can be classified into two types depending on the settling of particles along the pipeline, and the period is small for slug flow without the settled layer, which is called solitary slug flow. The pressure drop for soft particles is shown to be larger than that for hard particles. Then, experimental results are presented on horizontal fluidized-bed conveying of fine powders to show that air release from the top surface of the conveying channel is an imnortant factor for high mass flow rate of particles.

关键词： Low-velocity conveying Slug flow Soft particle Horizontal fluidized-bed conveying Fine powder