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成人教育 2007年第10期27卷 90-92页

作者：蓝建 Akhiro chiba 中央教育科学研究所教育理论研究部北京100088 联合国教科文组织

作为未完成使命和面临挑战的非正规教育,必须发挥其作用,必须重建人类和平与欢乐的愿望。

关键词：正规教育使命挑战

FUNCTION OF SPA DEVELOPMENT IN COUNTRYSIDE FOR DOMESTIC TOURISM IN CHINA──A Case Study of Some Spas in Liaoning Province

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Chinese Geographical Science 2000年第2期10卷 168-176页

作者： WANG Yan-ping YAMAMURA J.(Depertment of Geography, Liaoning Normal University, Dalian 116022, P.R.China)(chiba University Japan) Department of Geography Liaoning Normal University Dalian P. R. China chiba University Japan

The common problems on tourism of developing countries have often been researched by west researchers until now, which can be concluded into special words: "two sectors", "enclave construction", "government’s inteference", "developing scale", and "the industrial role of tourism" etc. In fact all the researches were done from the areas with the patronage of foreign visitors, how is the situation of domestic tourism was ignored in some points. In this paper, another developing model compatal with the one with foregn visitors was presented to the readers on the case studies of countryside spas in China. Through this research, one aspect of Chinese nd leisure life can be understood to some extent, and the implying that for bigger developing countries the domestic tourism can match the the effect of international tourism should not be ignored at least to China. As the developing of economy, domestic tourism will finally unile with international one together, and the common probleme will disappear step by step, there fre domestic tourism and international tourism of developing countries should be researched equally since now.

关键词： spa convalescent hospital(hotel) national investment personal investment

Effect of tumor necrosis factor-α antagonists on oxidative stress in patients with Crohn's disease

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World Journal of Gastroenterology 2015年第35期21卷 10208-10214页

作者： Kazunari Yamamoto Toshimi chiba Takayuki Matsumoto Division of Gastroenterology Department of Internal MedicineSchool of MedicineIwate Medical University

AIM: To investigate changes in oxidative stress in Crohn's disease(CD) before and after anti-tumor necrosis factor(TNF)-α ***: A total of 42 patients with active CD, who were scheduled to be treated by anti-TNF-α antibodies, were enrolled. Serum levels of diacron-reactive oxygen metabolites(d-ROM), biological antioxidant potential(BAP), and modified ratio of oxidative stress and antioxidant capacity(m-OA) were measured using the Free Radical Analytical System before and 8 wk after induction of therapy with infliximab or adalimumab. The values for oxidative stress were correlated with disease activity and clinical response as determined by the CD activity index(CDAI) at 8 and 54 wk after the ***: Prior to treatment, d-ROM showed significant correlations with CDAI(r = 0.42, P < 0.01). There was a significant negative correlation between m-OA and CDAI before and after treatment(r =-0.48 vs r =-0.42, P < 0.01). CDAI and d-ROM had decreased significantly by 8 wk after treatment(CDAI; 223.3 ± 113.2 vs 158.3 ± 73.4, P < 0.01, d-ROM; 373 ± 133 vs 312 ± 101, P < 0.05). However, neither BAP nor m-OA had changed significantly. In patients who had responded to the treatment at 8 wk, d-ROM, BAP, and m-OA levels before treatment did not differ significantly between patients with and without loss of ***: Anti-TNF-α therapy decreases oxi-dative stress in patients with CD, but does not alter the production of antioxidants. Dysregulation of antioxidants may be associated with the disease.

关键词： Crohn’s disease Severity Oxidative stress Anti-tum

Movement of Dislocations in the Sub-Surface of a Polycrystalline Metal by Cavitation Peening Observed by Transmission Electron Microscopy

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Materials Sciences and Applications 2015年第2期6卷 140-144页

作者： Osamu Takakuwa Akihiko chiba Hitoshi Soyama Department of Nanomechanics Graduate School of Engineering Tohoku University Sendai Japan Institute for Materials Research Tohoku University Sendai Japan

The impact produced when cavitation bubbles collapse can be utilized to modify surfaces in the same way as shot peening and it is called cavitation peening (CP). CP is one of a number of surface modification techniques used to improve the fatigue strength of metallic materials by introducing compressive residual stress. Although it has been shown by an X-ray diffraction method that CP decreases the micro-strain related to dislocations in the sub-surface of a polycrystalline material, the mechanism for this decrease is unclear. In this paper, the movement of dislocations by CP was observed using transmission electron microscopy (TEM).

关键词： Microstructure Transmission Electron Microscopy Dislocation Surface Modification Cavitation

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

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Recognition of tumor cells by Dectin-1 orchestrates innate i...

Expression of JunB Induced by X-rays in Mice

第九届全国免疫学学术大会

作者： Yoshitaka Kimura Shiho chiba Hiroaki Ikushima Hiroshi Ueki hideyuki Yanai Sho Hangai Junko Nishio Hideo Negishi Tomohiko Tamura Shinobu Saijo Yoichiro Iwakura Tadatsugu Taniguchi Department of Molecular Immunology and Center for International Research on Integrative Biomedical Systems Institute of Industrial ScienceThe University of Tokyo Max Planck-The University of Tokyo Center for Integrative Inflammology Core Research for Evolution Science and Technology Japan Science and Technology Agency Department of Immunology Yokohama City University Graduate School of Medicine Department of Molecular Immunology Medical Mycology Research CenterChiba University Center for Animal Disease Models Research Institute for Biomedical SciencesTokyo University of Science

Innate immune receptors play pivotal roles in the immune response against invading ***,the role of such receptors in anti-tumor immune responses is still *** gain insights into the role of innate immune

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Biomedical and Environmental Sciences 2004年第3期17卷 327-332页

作者： HONGWAN HIROSHIISHIHARA BeijingNeurosurgicalInstitute Beijing100050China／／BeijingNeurosurgicalInstituteTianTanXili6Bijing100050China NationalInstituteofRadiologicalSciences Chiba-shi263-8555Japan

Objective To explore JunB gene expression in spleen cells of mice after the whole body irradiation as well as in normal hematopoietic and leukemia cells in the primary culture after different dosages of X-ray irradiation. Methods Spleen cells were isolated from the mice irradiated with 3 Gy X-rays. Primary cultured cells from mice were incubated in different intervals after X-irradiation at different dosages. Total RNA was extracted from the cells and the fluctuation of JunB mRNA level was assessed by the RNA ratio of JunB/b-actin measured by quantitative Northern blot hybridization. Results After the mice were exposed to 3 Gy X-rays irradiation, JunB expression in spleen cells was remarkably and rapidly increased, and reached its peak 0.5 h later in C3H/He mice and 1 h later in Balb/c mice. In the primary culture of normal spleen and leukemia cells, JunB mRNA levels increased 30 min after irradiation. The enhanced levels of JunB mRNA were returned to a normal level within 240 min after irradiation. Conclusions JunB gene is responsive to ionizing irradiation and is induced at immediate-early phase after the stimulation. This suggests that the JunB gene plays an important role in the early process of the cells against radiation.

关键词： JunB Whole body irradiation Northern blot hybridization

Influence of stacking fault energy on formation of long period stacking ordered structures in Mg-Zn-Y-Zr alloys

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Progress in Natural Science:Materials International 2011年第6期21卷 485-490页

作者： Fu-sheng PAN~(1,2),Su-qin LUO~1,Ai-tao TANG~(1,2),Jian PENG~(1,2),Yun LU~3 1.College of Materials Science and Engineering,Chongqing University,Chongqing 400044,China 2.National Engineering Research Center for Magnesium Alloys,Chongqing University,Chongqing 400044,China 3.Faculty of Engineering,chiba University,chiba 263-8522,Japan College of Materials Science and Engineering Chongqing University Chongqing 400044 China National Engineering Research Center for Magnesium Alloys Chongqing University Chongqing 400044 China Faculty of Engineering Chiba University Chiba 263-8522 Japan

The influence of alloying elements on the stacking fault energy（SFE） of Mg-Y-Zn-Zr alloys was calculated by using first-principles,and the microstructure of as-cast Mg-1.05Y-0.79Zn-0.07Zr（mole fraction,%） alloy prepared by conventional casting was investigated by SEM,TEM and *** block-like long period stacking ordered（LPSO） phase,the lamellar LPSO phase and stacking faults were observed simultaneously and the lamellar LPSO structure and stacking faults were both formed on （0001）α-Mghabit plane and grown or extended along[01 1 0]α-*** calculation results by the first-principles showed that the addition of Y can sharply decrease the stacking fault energy of the Mg-Zn-Y-Zr alloy,while Zn slightly increases the stacking fault energy of the *** influence of stacking fault energy on the formation of LPSO was *** shows that LPSO may nucleate directly through stacking faults and the lower stacking fault energy was in favor of formation of LPSO.

关键词： magnesium alloy Mg-Zn-Y-Zr long period stacking ordered(LPSO) structures stacking fault energy(SFE) firstprinciples calculation

Investigation of the Chinese rolling tongue consonants

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Chinese Journal of Acoustics 2000年第1期19卷 10-21页

作者： ZHOU Ligang Keni’ti Kido (chiba institute of Technology 2-17-1, Tsudanuma Narashino-shi chiba, 275-0016, JAPAN) Ghiba Institute of Technology 2-17-1 Tsudanuma Narashino-shi Chiba 275-0016 JAPAN

Some special monosyllabic Chinese words which contain rolling tongue consonants are discussed. Based on the spectrum analysis, the special characteristic is found at a frequency higher than 3 kHz. The distinction is not only in the consonant part but also in the vowel part. The people in the north region of China distinguish the rolling tongue consonants from the straight tongue consonants both in utterance and in hearing, but those in the south region of China do not. The results of the hearing investigation using synthesized speech show that the consonant part corresponding to the normal one has more effect than the vowel part on the recognition of the words containing the rolling tongue consonant.

关键词： than ACTA

An Experimental Study on the Motion of Floating Bodies Arranged in Series for Wave Power Generation

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材料科学与工程（中英文A版） 2017年第6期7卷 281-289页

作者： Seiki chiba Kenta Hasegawa Mikio Waki Sho Kurita chiba Science Institute Yakumo Meguro-Ward Tokyo 152-0023 Japan National Maritime Research Institute 6-38-1 Shinkawa Mitaka-City Tokyo 181-0004 Japan Wits Inc. Oshiage Sakura-City Tochigi 329-1334 Japan Kureha Elastomer Co. Ltd Kanonnji-cho Tsu-City Mie 514-8511 Japan