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Effectiveness of Helicobacter pylori eradication in the treatment of early-stage gastric mucosa-associated lymphoid tissue lymphoma:An up-to-date meta-analysis

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World Journal of Gastroenterology 2023年第14期29卷 2202-2221页

作者： Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Mariana Santos Calmon Marcel Silva Luz Samuel Luca Rocha Pinheiro Clara Faria Souza Mendes dos Santos Gabriel Lima Correa Santos Hanna Santos Marques henrique affonso delgado Kádima Nayara Teixeira Cláudio Lima Souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029094BahiaBrazil Instituto de Saúde Coletiva Universidade Federal da BahiaSalvador 40110040BahiaBrazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45029094BahiaBrazil Campus Toledo Universidade Federal do ParanáToledo 85919899ParanáBrazil

BACKGROUND Gastric mucosa-associated lymphoid tissue(MALT)lymphoma(GML)is usually a low-grade B-cell neoplasia strongly associated with Helicobacter pylori(H.pylori)-induced chronic gastritis.Clinical practice guidelines currently recommend H.pylori eradication as the preferred initial treatment for early-stage GML.To determine the practical effect of bacterial eradication as the sole initial therapy for early-stage GML,an updated analysis and review of available evidence is imperative.AIM To perform a meta-analysis to assess the rate of complete remission(CR)of H.pylori-positive early-stage GML following bacterial eradication.METHODS We performed independent,computer-assisted literature searches using the PubMed/MEDLINE,Embase,and Cochrane Central databases through September 2022.Prospective and retrospective observational studies evaluating the CR of early-stage GML following bacterial eradication in H.pylori-positive patients.The risk of bias was assessed using Joanna Briggs Institute(JBI)Critical Appraisal Tools.The pooled estimate of the complete histopathological remission rate and respective confidence intervals(95%CI)were calculated following the random-effects model.Heterogeneity and inconsistency were assessed using Cochran’s Q test and I2 statistic,and heterogeneity was defined as P50%,respectively.Subgroup and meta-regression analyses were conducted to explore potential sources of heterogeneity.RESULTS The titles and abstracts of 1576 studies were screened;96 articles were retrieved and selected for full-text reading.Finally,61 studies were included in the proportional meta-analysis(P-MA).Forty-six were prospective and fifteen were retrospective uncontrolled,single-arm,observational studies.The overall risk of bias was low to moderate in all but a single report,with an average critical appraisal score across all studies of 79.02%.A total of 2936 H.pylori-positive early-stage GML patients,in whom H.pylori was successfully eradicated,were included in the analysis.The pooled CR of H.pylori-p

关键词： Lymphoma B-cell Marginal zone Gastric mucosa-associated lymphoid tissue lymphoma Stomach lymphoma Helicobacter pylori Therapeutics Eradication therapy

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Use of geospatial tools to predict the risk of contamination by SARS-CoV-2 in urban cemeteries

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Geoscience Frontiers 2022年第6期13卷 331-346页

作者： Paloma Carollo Toscan Alcindo Neckel Laércio Stolfo Maculan Cleiton Korcelski Marcos L.SOliveira Eliane Thaines Bodah Brian William Bodah henrique Aniceto Kujawa affonso Celso Gonalves Faculdade Meridional IMED304Passo FundoRS 99070-220Brazil Department of Civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia Universidad de Lima Departamento de Ingeniería civil y ArquitecturaAvenida Javier Prado Este 4600Santiago de Surco 1503Peru State University of New York Onondaga Community College4585 West SenecaTurnpikeSyracuseNY 13215USA Thaines and Bodah Center for Education and Development 840 South Meadowlark LaneOthelloWA 99344USA University of Perugia Piazza Università106123 PerugiaItaly State University of Western Paraná–UNIOESTE Center of Agrarian SciencesRua Pernambuco1777CentroMarechal Cândido RondonPR 85960-000Brazil

Urban cemeteries are increasingly surrounded by areas of high residential density as urbanization continues world-wide. With increasing rates of mortality caused by the novel coronavirus, SARS-CoV-2,urban vertical cemeteries are experiencing interments at an unprecedented rate. Corpses interred in the 3rd to 5th layer of vertical urban cemeteries have the potential to contaminate large adjacent regions.The general objective of this manuscript is to analyze the reflectance of altimetry, normalized difference vegetation index(NDVI) and land surface temperature(LST) in the urban cemeteries and neighbouring areas of the City of Passo Fundo, Rio Grande do Sul, Brazil. It is assumed that the population residing in the vicinity of these cemeteries may be exposed to SARS-CoV-2 contamination through the displacement of microparticles carried by the wind as a corpse is placed in the burial niche or during the first several days of subsequent fluid and gas release through the process of decomposition. The reflectance analyses were performed utilizing Landsat 8 satellite images applied to altimetry, NDVI and LST, for hypothetical examination of possible displacement, transport and subsequent deposition of the SARS-CoV-2 virus. The results showed that two cemeteries within the city, cemeteries A and B could potentially transport SARS-CoV-2 of nanometric structure to neighboring residential areas through wind action.These two cemeteries are located at high relative altitudes in more densely populated regions of the city.The NDVI, which has been shown to control the proliferation of contaminants, proved to be insufficient in these areas, contributing to high LST values. Based on the results of this study, the formation and implementation of public policies that monitor urban cemeteries is suggested in areas that utilize vertical urban cemeteries in order to reduce the further spread of the SARS-CoV-2 virus.

关键词： Remote sensing Reflectance temperature Atmospheric contamination Urban environment SARS-CoV-2

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Cultivation of Perennial Herbaceous Legumes in Weed Management in Coffee Plantation on the Cerrado

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Journal of Agricultural Science and Technology(B) 2013年第6期3卷 420-428页

作者： Julio Cesar Freitas Santos Aquiles Junior da Cunha Francisco affonso Ferreira Ricardo henrique Silva Santos Ney Sussumu Sakiyama Paulo Cesar de Lima Brazilian Agricultural Research Corporation-Embrapa Brasilia Distrito Federal 70770-901 Brazil Agronomy Academical Center of the Cerrado-Patroclnio Patroclnio Minas Gerais 38740-000 Brazil Department of Crop Science Universidade Federal de Vigosa Vicosa Minas Gerais 36571-000 Brazil Minas Gerais Agricultural Research Corporation-Epamig Vigosa Minas Gerais 36571-000 Brazil

The aim of this study was to evaluate the cultivation of perennial herbaceous legumes on weed control and yield of the coffee crop in the Cerrado. The experimental design was a randomized complete block with four replications. The 10 treatments tested in factorial 4 × 2 + 2, were four legumes: forage peanut (Arachis pintoi), hybrid Java (Macrotyloma axillare), perennial soybean (Neonotonia wightii) and wild ground nut (Calopogonium mucunoides); two forms in the interrows of coffee plants with two and three rows of legumes spaced by 0.50 m and 0.25 m, respectively; and two additional treatments consisted of hand weeding with hoe and chemical control with glyphosate. The hybrid Java and wild ground nut in the first year and the hybrid Java and perennial soybean in the second year, all followed by forage peanut, promoted lower density and biomass of the weeds. The wild ground nut in the first year and forage peanut in the second year showed higher soil cover. The hybrid Java had its highest biomass production in two years, and wild ground nut being higher in the first year. The cultivation of perennial herbaceous legumes promoted weed control without interfering in the productivity of the coffee crop.

关键词：多年生草本豆科植物植物栽培杂草管理种植园咖啡平托花生 Java

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Mean and Interannual Variability of Maize and Soybean in Brazil under Global Warming Conditions

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American Journal of Climate Change 2013年第4期2卷 237-253页

作者： Flávio Justino Evandro Chaves Oliveira Rafael de Avila Rodrigues Paulo henrique Lopes Goncalves Paulo Jorge Oliveira Ponte Souza Frode Stordal José Marengo Thieres G.da Silva Rafael Coll delgado Douglas da Silva Lindemann Luiz Claudio Costa Departamento de Engenharia Agrícola Universidade Federal de ViçosaVicosaBrazil Universidade Federal Rural da Amazônia Instituto Sócio-Ambiental e dos Recursos HídricosBelémBrazil Department of Geosciences University of OsloOsloNorway Instituto Nacional de Pesquisas Espaciais Cachoeira PaulistaBrazil Universidade Federal Rural de Pernambuco Unidade Academica de Serra TalhadaSerra TalhadaBrazil Universidade Federal Rural do Rio de Janeiro Instituto de Florestas/Departamento de Ciencias AmbientaisSeropédicaBrazil

Brazil is responsible for 27% of the world production of soybeans and 7% of maize. Mato Grosso and Para states in Brazil are among the largest producer. The viability to the cultivation of maize (Zea mays) and soybeans (Glycine max), for future climate scenarios (2070-2100, GHG) is evaluated based on crop modeling (DSSAT) forced by observational data and regional climate simulations (HadRM3). The results demonstrated that a substantial reduction in the yield in particular for maize may be expected for the end of the 21st century. Distinct results are found for soybeans. By applying the A2 climate changes scenario, soybean yield rises by up top 60% assuming optimum soil treatment and no water stress. However, by analyzing the inter-annual variability of crop yields for both maize and soybean, could be demonstrated larger year-to-year fluctuations under greenhouse warming conditions as compared to current conditions, leading to very low productivity by the end of the 21st century. Therefore, these Brazilian states do not appear to be economically suitable for a future cultivation of maize and soybeans. Improved adaptation measures and soil management may however partially alleviate the negative climate change effect.

关键词： Climate Changes Soybeans Maize

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Hydrodynamics and suspended particulate matter retention in macrotidal estuaries located in Amazonia-semiarid interface(Northeastern-Brazil)

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International Journal of Sediment Research 2020年第4期35卷 417-429页

作者： Vinicius henrique Maciel dos Santos Francisco Jose da Silva Dias Audalio Rebelo Torres Romulo Araujo Soares Lais Costa Terto Antonio Carlos Leal de Castro Ricardo Luvizotto Santos Marco Valerio Jansen Cutrim Laboratorio de Hidrodinamica Costeira Estuarina e de Aguas Interiores (LHiCEAI) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA)Cidade Universitaria Dom Delgado Laboratorio de Ictiologia (LabIctio) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado Laboratorio de Ecotoxicologia (LabEcotox) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado Laboratorio de Ficologia (LabFic) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado

The aim of the current study was to determine the nature of the seasonal variability of the Suspended Particulate Matter(SPM) fluxes from the drainage basin to the estuary in a macrotidal region(Northeastern Brazil),and the estuarine response to a seawater intrusion regarding sediment deposition,which will support the understanding of the global transport of materials at the continent-ocean interface.Thermohaline structure data was acquired using a Conductivity,Temperature,and Depth(CTD) probe with a sampling frequency of 4 Hz.Suspended particulate material was measured by gravimetric measurements applied to exact filtered volume samples.The outflows were measured through the use of an Acoustic Doppler Current Profiler(ADCP) with frequency of 1.5 MHz.The horizontal thermal and saline gradients varied from warmer and less saline waters(2014) to cooler and saline waters(2015).The gradient behavior when linked to volume transport and SPM flows,suggests a minimization of the fluvial flows in 2015,easing the advance of coastal water(CW) towards the inner estuary,leading to an inversion of the baroclinic pressure gradient.The bottom saline front,generated by the entrance of coastal water masses,caused an increase in SPM concentrations due to increased fluid density,resuspension of previously deposited sediment,and erosion of banks.High concentrations of SPM indicate higher volume transport suggesting a hydraulic barrier due to the change/inversion of the baroclinic pressure gradient,resulting in water and material retention.Material deposition was observed during neap tide,while during spring tide the material is resuspended,increasing the concentration,generating cycles of deposition and erosion during the neap-spring tides.The sediment in suspension that reach the estuary,even with low fluvial volume,stay in this environment forming new islands because of deposition.High deposition rates or sediment cycling,if generated by the hydraulic barrier,may indicate that the flows of SPM from the continental drainage to the e

关键词： Brazilian Amazonia Materials discharges Macrotidal estuaries Freshwater percentage Residence time

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Essential Oils of Lavandula stoechas subsp.luisieri as Antifungal Agent against Fungi from Strawberry Tree Fruit

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Journal of Pharmacy and Pharmacology 2021年第3期9卷 98-106页

作者： Joana Domingues Fernanda delgado JoséCarlos Gonçalves Cristina Santos Pintado CBPBI-Plant Biotechnology Centre of Beira Interior Quinta da Senhora de MérculesApartado 1196001-909Castelo BrancoPortugal CICS-UBI-Health Sciences Research Centre Universidade da Beira InteriorAv.Infante D.Henrique 6200-506CovilhãPortugal IPCB-ESA-Instituto Politécnico de Castelo Branco Escola Superior AgráriaQuinta da Senhora de MérculesApartado 1196001-909Castelo BrancoPortugal CERNAS-IPCB-Research Centre for Natural Resources Environment and SocietyInstituto Politécnico de Castelo BrancoPortugal

L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.

关键词： Portuguese short-stalked lavender Hydrodistillation Gas Chromatography Chemical characterization Minimum inhibitory concentration Minimum fungicidal concentration.

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