Essential Oils of Lavandula stoechas *** as Antifungal Agent against Fungi from Strawberry Tree Fruit

作     者：Joana Domingues Fernanda Delgado JoséCarlos Gonçalves Cristina Santos Pintado 

作者机构：CBPBI-Plant Biotechnology Centre of Beira InteriorQuinta da Senhora de MérculesApartado 1196001-909Castelo BrancoPortugal CICS-UBI-Health Sciences Research CentreUniversidade da Beira InteriorAv.Infante D.Henrique 6200-506CovilhãPortugal IPCB-ESA-Instituto Politécnico de Castelo BrancoEscola Superior AgráriaQuinta da Senhora de MérculesApartado 1196001-909Castelo BrancoPortugal CERNAS-IPCB-Research Centre for Natural ResourcesEnvironment and SocietyInstituto Politécnico de Castelo BrancoPortugal 

出 版 物：《Journal of Pharmacy and Pharmacology》 (药剂与药理学（英文版）)

年 卷 期：2021年第9卷第3期

页      面：98-106页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：CENTRO 2020 PROVERE-Operational Program CENTRO-04-3928-FEDER-000009 Strawberry TreeInnovation Platform Action Portugal 2020 and European Union by FEDER and by COOP4PAM-Cooperar para crescer no setor das plantas aromáticas e medicinais-Projeto INTERREG/Programa Espanha-Portugal(POCTEP) 0665_COOP4PAM_4_P 

主　　题：Portuguese short-stalked lavender Hydrodistillation Gas Chromatography Chemical characterization Minimum inhibitory concentration Minimum fungicidal concentration. 

摘      要：*** *** is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in *** chemical profile and antifungal activity of *** *** essential oils were *** essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/*** minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry *** fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium *** oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.