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Gut virome:New key players in the pathogenesis of inflammatory bowel disease

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World Journal of Methodology 2025年第2期15卷 27-43页

作者： helal F Hetta Rehab Ahmed Yasmin N Ramadan Hayam Fathy Mohammed Khorshid Mohamed M Mabrouk Mai Hashem Department of Medical Microbiology and Immunology Faculty of MedicineAssiut UniversityAssiut 71515Egypt Division of Microbiology Immunology and BiotechnologyFaculty of pharmacyUniversity of TabukTabuk 71491Saudi Arabia Division of Microbiology Immunology and BiotechnologyDepartment of Natural Products and Alternative MedicineFaculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Department of Internal Medicine Division HepatogastroenterologyAssiut UniversityAssiut 71515Egypt Department of Clinical Research Egyptian Developers of Gastroenterology and Endoscopy FoundationCairo 11936Egypt Department of Internal Medicine Faculty of Medicine.Tanta UniversityTanta 31527Egypt Department of Tropical Medicine Gastroenterology and HepatologyAssiut University HospitalAssiut 71515Egypt

Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the *** the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immunological response,environmental exposure,particularly the gut microbiota,and genetic suscept-ibility represents the major *** gut virome is a group of viruses found in great frequency in the gastrointestinal tract of *** gut virome varies greatly among individuals and is influenced by factors including lifestyle,diet,health and disease conditions,geography,and *** majority of research has focused on the significance of gut bacteria in the progression of IBD,although viral populations represent an important component of the *** conducted this review to highlight the viral communities in the gut and their expected roles in the etiopathogenesis of IBD regarding published research to date.

关键词： Inflammatory bowel disease Pathogenesis Gut virome Bacteriophage Eukaryotic viruses

Subgroup Discovery Algorithms： A Survey and Empirical Evaluation

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Journal of Computer Science & Technology 2016年第3期31卷 561-576页

作者： Sumyea helal School of Information Technology and Mathematical Sciences University of South Australia Adelaide SA5001 Australia

Subgroup discovery is a data mining technique that discovers interesting associations among different variables with respect to a property of interest. Existing subgroup discovery methods employ different strategies for searching, pruning and ranking subgroups. It is very crucial to learn which features of a subgroup discovery algorithm should be considered for generating quality subgroups. In this regard, a number of reviews have been conducted on subgroup discovery. Although they provide a broad overview on some popular subgroup discovery methods, they employ few datasets and measures for subgroup evaluation. In the light of the existing measures, the subgroups cannot be appraised from all perspectives. Our work performs an extensive analysis on some popular subgroup discovery methods by using a wide range of datasets and by defining new measures for subgroup evaluation. The analysis result will help with understanding the major subgroup discovery methods, uncovering the gaps for further improvement and selecting the suitable category of algorithms for specific application domains.

关键词： subgroup discovery searching pruning measure evaluation

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ACHILLES HEEL （Cord）

中华骨科杂志 1995年第1期15卷 43-48页

作者：Ｂ．ＨＥＬＡＬ

ＡＣＨＩＬＬＥＳＨＥＥＬ（Ｃｏｒｄ）Ｂ．ＨＥＬＡＬＲｅｃｍｖｅｄ１０Ｊｕｌｙ１９９３Ｔｈｅｔｅｎｄｏｎｉｔｓｅｌｆｉｓａｎｅｎｏｒｍｏｕｓｌｙｓｔｒｏｎｇｓｔｒｕｃｔｕｒｅａｎｄｗｈｅｎｎｏｒｍａｌｉｔｓｉｎｕｓｃｌ... 详细信息

ＡＣＨＩＬＬＥＳＨＥＥＬ（Ｃｏｒｄ）Ｂ．ＨＥＬＡＬＲｅｃｍｖｅｄ１０Ｊｕｌｙ１９９３Ｔｈｅｔｅｎｄｏｎｉｔｓｅｌｆｉｓａｎｅｎｏｒｍｏｕｓｌｙｓｔｒｏｎｇｓｔｒｕｃｔｕｒｅａｎｄｗｈｅｎｎｏｒｍａｌｉｔｓｉｎｕｓｃｌｅｂｅｌｌｙｏｒｔｈｅｏｓｃａｌｃ...

关键词：跟腱断裂石膏固定肌腱附着点 ACHILLES HEEL Cord

Effects of grid size on predictions of bed expansion in bubbling fluidized beds of Geldart B particles： A generalized rule for a grid-independent solution of TFM simulations

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Particuology 2017年第5期15卷 61-69页

作者： M. helal Uddin Charles J. Coronella Department of Chemical and Materials Engineering University of Nevada Reno NV 89557 USA

Numerical simulations of gas-solid fluidized beds based on the kinetic theory of granular flow exhibit a significant dependence on domain discretization. Bubble formation, bubble size and shape all vary greatly with the discretization, and the use of an inappropriate scale resolution leads to inaccurate predictions of fluidization hydrodynamics. In this study, grid-independent solutions of the two fluid model were examined by comparing the bed expansions obtained from numerical simulations with experimental results and empirical predictions, based on bubbling fluidized beds of Geldart B particles. Grid indepen- dence was achieved with a grid resolution equal to 18 times the particle diameter. The simulation results were compared with previously published data for verification purposes. The results of this work should provide a guideline for choosing the appropriate grid size and thereby minimize the time and expense associated with large simulations.

关键词： Mesh effectHydrodynamicsComputational fluid dynamicsEuler-Euler method MFIX

A new approach for fuel injection into a solar receiver/ reactor:Numerical and experimental investigation

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Frontiers of Chemical Science and Engineering 2018年第4期12卷 683-696页

作者： M helal Uddin Nesrin Ozalp Jens Heylen Cedric Ophoff Mechanical and Industrial Engineering Department University of Minnesota DuluthDuluthMN 55812-3042USA Mechanical Engineering Department 3001 LeuvenBelgium

An innovative and efficient design of solar receivers/reactors can enhance the production of clean fuels via concentrated solar energy. This study presents a new jet-type burner nozzle for gaseous feedstock injection into a cavity solar receiver inspired from the combustion technology. The nozzle design was adapted from a combustion burner and successfully implemented into a solar receiver and studied the influence of the nozzle design on the fluid mixing and temperature distribution inside the solar receiver using a 7 kW solar simulator and nitrogen as working fluid. Finally, a thorough computational fluid dynamics (CFD) analysis was performed and validated against the experimental results. The CFD results showed a variation of the gas flow pattern and gas mixing after the burner nozzle adaptation, which resulted an intense effect on the heat transfer inside the solar receiver.

关键词： solar reactor nozzle CFD heat transfer mixing and recirculation

^14CO2 Fixation and Translocation of Photoassimilates as Selection Criteria of Egyptian Taro Genotypes

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Journal of Integrative Plant Biology 2006年第5期48卷 563-566页

作者： helal Ragab Moussa Afaf Abd EI-Kader Salem Radioisotopes Department Atomic Energy Authority Cairo Egypt Horticultural Research Institute Agriculture Research Center Giza Egypt

The growth characterlstlcs, different physlological parameters, photosynthetic activity （^14CO2 fixation）, and the translocatlon rate of photoassimllates In different taro （Colocasia esculenta L. Schott） genotypes was studled In order to determlne the posslble use of these parameters as selectlon crlterla for dlfferent wldely used genotypes of taro （Delta No. 9, 15, 20, 21, and balady）. The results obtalned suggest that Delta No. 21 shows the most slgnlflcant increase In all parameters tested compared wlth the control （balady）, followed by Delta No. 9, 15, and 20, respectively. The results show a positive correlation between photosynthetlc actlvlty, translocatlon efflclency, and total yield. The selected clone Delta No. 21 Is recommended for cultlvatlon In the delta reglon of Egypt.

关键词： ^14CO2 fixation taro (Colocasia esculenta) translocation rate.

A broad learning-based comprehensive defence against SSDP reflection attacks in IoTs

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Digital Communications and Networks 2023年第5期9卷 1180-1189页

作者： Xin Liu Liang Zheng Sumi helal Weishan Zhang Chunfu Jia Jiehan Zhou College of Computer Science and Technology China University of Petroleum(East China)QingdaoChina School of Computing Lancaster University UK Nankai University TianjinChina Information Technology and Electrical Engineering University of OuluFinland

The proliferation of Internet of Things(IoT)rapidly increases the possiblities of Simple Service Discovery Protocol(SSDP)reflection *** DDoS attack defence strategies deploy only to a certain type of devices in the attack chain,and need to detect attacks in advance,and the detection of DDoS attacks often uses heavy algorithms consuming lots of computing *** paper proposes a comprehensive DDoS attack defence approach which combines broad learning and a set of defence strategies against SSDP attacks,called Broad Learning based Comprehensive Defence(BLCD).The defence strategies work along the attack chain,starting from attack sources to *** defends against attacks without detecting attacks or identifying the roles of IoT devices in SSDP reflection *** also detects suspicious traffic at bots,service providers and victims by using broad learning,and the detection results are used as the basis for automatically deploying defence strategies which can significantly reduce DDoS *** evaluations,we thoroughly analyze attack traffic when deploying BLCD to different defence *** show that BLCD can reduce the number of packets received at the victim to 39 without affecting the standard SSDP service,and detect malicious packets with an accuracy of 99.99%.

关键词： Denial-of-service DRDoS SSDP reflection Attack Broad learning Traffic detection

Lymphocytic colitis: A clue to bacterial etiology

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World Journal of Gastroenterology 2005年第46期11卷 7266-7271页

作者： Thanaa EA helal Naglaa S Ahmed Osama Abo El Fotoh Department of PathologyFaculty of Medicine Ain Shams UniversityEgypt Department of Internal MedicineFaculty of Medicine Ain Shams UniversityEgypt

AIM： To find out the role of bacteria as a possible etiological factor in lymphocytic colitis. METHODS： Twenty patients with histopathological diagnosis of lymphocytic colitis and 10 normal controls were included in this study. Colonoscopic biopsies were obtained from three sites （hepatic and splenic flexures and rectosigmoid region）. Each biopsy was divided into two parts. A fresh part was incubated on special cultures for bacterial growth. The other part was used for the preparation of histologic tissue sections that were examined for the presence of bacteria with the help of Giemsa stain. RESULTS： Culture of tissue biopsies revealed bacterial growth in 18 out of 20 patients with lymphocytic colitis mostly Escherichia coil （14/18）, which was found in all rectosigmoid specimens （14/14）, but only in 8/14 and 6/14 of splenic and hepatic flexure specimens respectively. In two of these cases, E coli was associated with proteus. Proteus was found only in one case, Klebsiella in two cases, and Staphylococcus aureus in one case. In the control group, only 2 out of 10 controls showed the growth of E coli in their biopsy cultures. Histopathology showed rod-shaped bacilli in the tissue sections of 12 out of 14 cases with positive E coli in their specimen＇s culture. None of the controls showed these bacteria in histopathological sections. CONCLUSION： This preliminary study reports an association between E coli and lymphocytic colitis, based on histological and culture observations. Serotyping and molecular studies are in process to assess the role of E coli in the pathogenesis of lymphocytic colitis.

关键词： Lymphocytic colitis E coli Histopathology Culture

Dissolved gas analysis and dissipation factor measurement of mineral oil-based nanofluids under thermal and electrical faults

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High Voltage 2023年第3期8卷 455-465页

作者： Ahmed Maher Diaa-Eldin A.Mansour Khaled helal Ramadan A.A.Abd El Aal Department of Electrical Engineering Faculty of EngineeringPort-Said UniversityPort-SaidEgypt Department of Electrical Power Engineering Faculty of EngineeringEgypt-Japan University of Science and Technology(E-JUST)New Borg El-Arab CityAlexandriaEgypt Department of Electrical Power and Machines Engineering Faculty of EngineeringTanta UniversityTantaEgypt

Mineral oil is the most frequent insulating liquid used in oil-immersed transformers for electrical insulation and heat ***,oil-based nanofluids are becoming more popular in scientific research as they have proved to have better dielectric and thermal *** applying these nanofluids into actual transformers,they would be exposed to thermal and electrical ***,The aim of the authors is to investigate the generation pattern of dissolved gases in nanofluids under thermal and electrical faults and to assess the applicability of traditional Dissolved Gas Analysis(DGA)techniques if oil-based nanofluids are used in ***-based nanofluid samples were prepared using a magnetic stirrer and an ultrasonic homogeniser and then subjected to simulated thermal and electrical faults in the laboratory using properly sealed test *** types of metal oxides,Silicon dioxide,Titanium dioxide,and Aluminium oxide nanoparticles,have been used to prepare nanofluids with 0.02 g/L and 0.04 g/L *** gases released and dissolved into oil due to the simulated faults were analysed and compared to traditional mineral oil as a *** dielectric dissipation factor was obtained and analysed for all *** to the findings,the presence and concentration of nanoparticles were shown to influence the amount of gases *** a result,this research is crucial in guaranteeing that traditional DGA techniques can be employed in transformers that use oil-based nanofluids.

关键词： electrical thermal dioxide