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Violence study of healthcare workers and systems in the Caribbean:ViSHWaS-Caribbean study

World Journal of Methodology 2024年第3期14卷 106-118页

作者： Reshon Hadmon Daniella Myriam Pierre Akshat Banga Jacques W Clerville hans Mautong Precious Akinsanya Rajat Das Gupta Sama Soliman Tolupe M Hunjah Bamidele A Hunjah Hafeez Hamza Ruman Khurshid Qasba Faisal A Nawaz Salim Surani Rahul Kashyap Department of Medicine St.George University School of MedicineGrenada FZ818West Indies Department of Research Global Remote Research Scholar ProgramSt PaulMN 55101United States Department of Public Health Cuny Graduate School of Public Health and Health PolicyNew YorkNY 10027United States Department of Internal Medicine Sawai Man Singh Medical CollegeJaipur 302004India School of Public Health Georgia State UniversityAtlantaGA 30302United States Department of Sociology and Demography School of HealthUniversidad de Especialidades Espiritu SantoSamborondon 092301Ecuador Department of Medicine Holy Name Medical CenterTeaneckNJ 07666United States Department of Epidemiology and Biostatistics University of South CarolinaColumbiaSC 29208United States Department of Medicine Pavlov First State Medical University of St PetersburgSankt-Peterburg 197022Russia Department of Medicine University of SuffolkIpswich IP41QJUnited Kingdom Department of Medicine Unicaf University of ZambiaLusaka 20842Zambia Department of Pharmacy School of PharmacyGirne 99428Cyprus Department of Medicine Sher-i-KashmirInstitute of Medical ScienceSrinagar 190011India Department of Psychiatry Al Amal Psychiatric HospitalEmirates Health ServicesDubaiUnited Arab Emirates Department of Medicine and Pharmacology Texas A and M UniversityCollege StationTX 77843United States Anesthesiology and Critical Care Mayo ClinicRochesterMN 55905United States Department of Research Wellspan HealthYorkPA 17403United States

BACKGROUND Violence against healthcare workers(HCWs)in the Caribbean continues to prevail yet remains *** aim is to determine the cause,traits,and consequences of violence on HCWs in the *** To determine the cause,traits,and consequences of violence on HCWs in the *** This research adopted an online cross-sectional survey approach,spanning over eight weeks(between June 6th and August 9th,2022).The survey was generated using Research Electronic Data Capture forms and followed a snowballing strategy to contact individuals using emails,social media,text messages,*** regression analysis was performed to evaluate the variables that influence violence,including gender,age,years of experience,institution type,and night shift *** The survey was completed by 225 *** comprised 61%.Over 51%of respondents belonged to the 21 to 35 age ***(n=61),Haiti(n=50),and Grenada(n=31)had the most *** HCWs(49%)worked for government academic institutions,followed by community hospitals(23%).Medical students(32%),followed by attending physicians(22%),and others(16%)comprised the most common cadre of *** 39%of the participants reported experiencing violence themselves,and 18%reported violence against colleague(s).Verbal violence(48%),emotional abuse(24%),and physical misconduct(14%)were the most common types of *** 63%of respondents identified patients or their relatives as the most frequent *** logistic regression analyses demonstrated that female gender(OR=2.08;95%CI:1.16-3.76,P=0.014)and higher frequency of night shifts(OR=2.22;95%CI:1.08-4.58,P=0.030)were associated with significantly higher odds of experiencing *** than 50%of HCWs felt less motivated and had decreased job satisfaction post-violent *** A large proportion of HCWS in the Caribbean are exposed to violence,yet the phenomenon remains *** a result,HCWs’job s

关键词： ViSHWaS Healthcare workers Violence Survey Workplace violence Caribbean Cross-sectional study

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Up and down the spectrum:upconversion nanocrystal and semiconductor material fused into a single nanocomposite

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Light(Science & Applications) 2022年第7期11卷 1331-1333页

作者： hans H.Gorris Zdeněk Farka Department of Biochemistry Masaryk University62500 BrnoCzech Republic

A nanocomposite consisting of a cubic EuSe semiconductor material grown on a hexagonal upconversion nanoparticle has overcome the crystal lattice mismatch that typically prevents the epitaxial growth of such heterogeneous ***^(3+)at the interface layer shows its characteristic red emission band both under UV excitation light due to energy transfer from the semiconductor and under NIR excitation light due to energy transfer after *** storage and security applications are suggested for this new nanocomposite.

关键词： excitation fused overcome

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Persistent astrocytic IL-3 stimulation of microglia slows disease in Alzheimer’s:treatment perspectives for Alzheimer’s

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Signal Transduction and Targeted Therapy 2021年第12期6卷 3369-3370页

作者： Natja Haag hans Zempel Institute of Human Genetics Medical FacultyRWTH Aachen UniversityAachenGermany Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany

In their new paper,McAlpine and colleagues provide compelling evidence that astrocyte dependent microglial stimulation is crucial for fighting off one of the most prominent Alzheimer disease(AD)pathological hallmarks,namelyβ-amyloid(Aβ)plaque *** find that(i)a subpopulation of astrocytes secrete the classical cytokine interleukin-3(IL-3),(ii)microglia are responsive to this cytokine,(iii)responsiveness(not so much secretion of IL-3)is increased in patients with AD and model systems of AD,and(iv)presence of IL-3 is necessary to allow microglia to counteract some of the detrimental effects of AD:if IL-3 is missing,AD pathology worsens(see Fig.1 for graphical depiction).1 AD and related tauopathies,e.g.,frontotemporal dementia(FTD)or frontotemporal lobar degeneration with tauopathy(FTLDTAU),are detrimental diseases,impose a huge burden on patients and caregivers,and are the scourge of modern healthcare *** recent advances in(immuno-)therapies,a causative cure seems out of range.

关键词： stimulation Alzheimer degeneration

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Schwann cell Miz without POZ:degeneration meets regeneration

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Neural Regeneration Research 2015年第10期10卷 1563-1564页

作者： David Fuhrmann hans-Peter Elsasser Department of Cytobiology and Cytopathobiology Philipps University of Marburg

Peripheral motor and sensory neuropathies are diseases with different etiologies emerging from genetic disorders,diabetes,infection or inflammation,paraneoplastic damage or intoxications including alcohol abuse（Marty... 详细信息

关键词： cell Schwann cell Miz without POZ

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Putative roles of cathepsin B in Alzheimer's disease pathology: the good, the bad, and the ugly in one?

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Neural Regeneration Research 2018年第12期13卷 2100-2101页

作者： hans-Gert Bernstein Gerburg Keilhoff Department of Psychiatry Otto v.Guericke University Magdeburg Institute of Biochemistry and Cell Biology Otto v.Guericke University Magdeburg

Alzheimer＇s disease（AD）is a fatal progressive neurodegenerative disorder characterized by loss in memory,cognition,and executive function and activities of daily *** pathogenesis has been shown to involve loss of neurons and synapses,cholinergic deficits,amyloid-beta protein（Aβ）deposition,tau protein hyperphosphorylation, and neuroinflammation.

关键词： AD and the ugly in one the bad the good Putative roles of cathepsin B in Alzheimer’s disease pathology

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Schwann cell Myc-interacting zinc-finger protein 1 without pox virus and zinc finger： epigenetic implications in a peripheral neuropathy

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Neural Regeneration Research 2018年第9期13卷 1534-1537页

作者： David Fuhrmann hans-Peter Elsaisser Department of Cytobiology and Cytopathobiology Philipps University of Marburg Marburg Germany

Functionality of adult peripheral nerves essentially relies on differentiation of Schwann cells during post- natal development, as well as fine-tuned re- and transdifferentiation in response to peripheral nerve injury. Epigenetic histone modifications play a major role during the differentiation of embryonic stem cells and diverse organ specific progenitor cells, yet only little is known about the epigenetic regulation of Schwa nn cells. Just recently, Fuhrmann et al. reported how the transcription factor Myc-interacting zinc-finger protein 1 （Mizl） might contribute to Schwann cell differentiation through repression of the histone de- methylase Kdm8. Here, we discuss the potential novel role of Mizl in Schwann cell differentiation and give a short overview about previously reported histone modifications underlying peripheral nerve develop- ment and response to injury.

关键词： Schwann celh differentiation peripheral nerve injury histone methylation epigenetics Mizl

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Toward managing mixed-species stands： from parametrization to prescription

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Forest Ecosystems 2017年第4期4卷 286-302页

作者： hans Pretzsch Eric K. Zenner Chair for Forest Growth and Yield Science Center of Life and Food Sciences Weihenstephan Technical University of Munich Hans-Carl-von Carlowitz-Platz 2 85354 Freising Germany

A better understanding and a more quantitative design of mixed-species stands will contribute to more integrative and goal-oriented research in mixed-species forests. Much recent work has indicated that the structure and growth of mixed species forests may fundamentally differ from monocultures. Here we suggest how to progress from the present accumulation of phenomenological findings to a design of mixed-species stands and advanced silvicultural prescriptions by means of modelling. First, the knowledge of mixing effects on the structure and growth at the stand, species, and individual tree level is reviewed, with a focus on those findings that are most essential for suitable modelling and silvicultural designs and the regulation of mixed stands as opposed to monocultures. Then, the key role of growth models, stand simulators, and scenario assessments for designing mixed species stands is discussed The next section illustrates that existing forest stand growth models require some fundamental modifications to become suitable for both monocultures and mixed-species stands. We then explore how silvicultural prescriptions derived from scenario runs would need to be both quantified and simplified for transfer to forest management and demonstrated in training plots. Finally, we address the main remaining knowledge gaps that could be remedied through empirical research.

关键词： Multiplicative mixing effects Overyielding Overdensity Modelling mixing effects Scenario analysis,Silvicultural prescriptions Practical guidelines

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Morrey smoothness spaces:A new approach

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Science China Mathematics 2023年第6期66卷 1301-1358页

作者： Dorothee D.Haroske hans Triebel Institute of Mathematics Faculty of Mathematics and Computer ScienceFriedrich Schiller University JenaJena 07743Germany

In the recent years,the so-called Morrey smoothness spaces attracted a lot of *** can(also)be understood as generalisations of the classical spaces A_(p,q)^(s)(R^(n))with A∈{B,F}in R^(n),where the parameters satisfy ... 详细信息

关键词： Morrey space smoothness space of Morrey type Besov-Morrey space Triebel-Lizorkin-Morrey space Besov-type space Triebel-Lizorkin-type space

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Wafer-scale fabricated thermo-pneumatically tunable microlenses

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Light(Science & Applications) 2014年第1期3卷 298-303页

作者： Wei Zhang hans Zappe Andreas Seifert Department of Microsystems Engineering University of Freiburg79110 FreiburgGermany

We have developed a self-contained,liquid tunable microlens based on polyacrylate membranes integrated with compact on-chip thermo-pneumatic actuation fabricated using full-wafer *** oil is used as the optical liquid,which is pushed or pulled into the lens cavity via an extended microfluidic channel structure without any pumps,valves or other mechanical *** heat load generated by the thermal actuator is physically isolated from the lens *** back focal length may be tuned from infinity to 4 mm with a maximum power consumption of 300 *** principal application is fine tuning of the back focal length,for which tuning time constants as small as 100 ms are suitable.

关键词： optofluidics thermo-pneumatic actuation tunable microlens wafer-scale fabrication

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Drought can favour the growth of small in relation to tall trees in mature stands of Norway spruce and European beech

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Forest Ecosystems 2018年第3期5卷 258-276页

作者： hans Pretzsch Gerhard Schutze Peter Biber Center of Life and Food Sciences Weihenstephan Technical University of MunichHans-Carl-von-Carlowitz-Platz 285354 FreisingGermany

Background: Climate change triggered many studies showing that trends and events of environmental conditions can reduce but also accelerate growth at the stand and individual tree level. However, it is still rather unknown how climate change modifies the growth partitioning between the trees in forest ***: Based on long-term girth-tape measurements in mature monospecific and mixed-species stands of Norway spruce(Picea abies(L.) Karst.) and European beech(Fagus sylvatica L.) we traced the effect of the severe droughts in 2003 and 2015 from the stand down to the tree ***: Stand growth of Norway spruce decreased by about 30% in the once-in-a-century drought 2015, while European beech was much more drought resistant. Water availability generally amplified size-asymmetric growth partitioning. Especially in case of Norway spruce water availability primarily fostered the growth of predominant trees, whereas drought favoured the growth of small trees at the expense of the predominant ones. We could not detect significant differences between mixed and monospecific stands in this ***: The drought-induced reallocation of growth in favour of small trees in case of spruce may result from its isohydric character. We hypothesize that as small trees are shaded, they can benefit from the reduced water consumption of their sun-exposed taller neighbours. In case of beech, as an anisohydric species, tall trees suffer less and smaller trees benefit less under drought. The discussion elaborates the consequences of the water dependent growth allocation for forest monitoring, growth modelling, and silviculture.

关键词： Growth partitioning Drought Competition symmetry Climate change Norway spruce European beech

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