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Neural Regeneration Research 2017年第8期12卷 1375-1376页

作者： Sang ryong kim School of Life Sciences BK21 plus KNU Creative BioResearch Group Brain Science and Engineering Institute Kyungpook NationalUniversity Daegu Korea

The progressive degeneration of nigral dopaminergic（DA）neurons and the biochemical reduction of striatal dopamine levels are associated with major clinical symptoms,including tremor at rest,rigidity of the limbs,slo... 详细信息

关键词： Naringin as a beneficial natural product against degeneration of the nigrostriatal dopaminergic projection in the adult brain DA TOR PD

Flexible kesterite thin-film solar cells under stress

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npj Flexible Electronics 2022年第1期6卷 863-870页

作者： ha Kyung Park Yunae Cho Juran kim Sammi kim Sungjun kim Jeha kim Kee-Jeong Yang Dae-Hwan kim Jin-Kyu Kang William Jo Department of Physics Ewha Womans UniversitySeoul 03760Republic of Korea Division of Energy Technology Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea Department of Solar&Energy Engineering Cheongju UniversityCheongju 28503Republic of Korea

Understanding the stress-induced phenomena is essential for improving the long-term application of flexible solar cells to non-flat ***,we investigated the electronic band structure and carrier transport mechanism of Cu2ZnSn(S,Se)4(CZTSSe)photovoltaic devices under mechanical *** efficient flexible CZTSSe devices were fabricated controlling the Na *** electronic structure of CZTSSe was deformed with stress as the band gap,valence band edge,and work function *** properties of the bent CZTSSe surface were probed by Kelvin probe force microscopy and the CZTSSe with Na showed less degraded carrier transport compared to the CZTSSe without *** local open-circuit voltage(VOC)on the bent CZTSSe surface decreased due to limited carrier *** reduction of local VOC occurred larger with convex bending than in concave bending,which is consistent with the degradation of device *** study paves the way for understanding the stress-induced optoelectronic changes in flexible photovoltaic devices.

关键词： optoelectronic stress bending

Limited therapeutic potential of astrocyte elevated gene-1 transduction in an animal model of Parkinson’s disease

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Neural Regeneration Research 2020年第10期15卷 1850-1851页

作者： Eunju Leem Sang ryong kim School of Life Sciences BK21 plus KNU Creative BioResearch GroupKyungpook National UniversityDaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

Biological roles of astrocyte elevated gene-1(AEG-1):AEG-1,also known as metadherin,was originally identified as a human immunodeficiency virus-1-and tumor necrosis factor-alpha-inducible gene in human fetal *** increase in AEG-1 expression is a well-established and important oncogenic event in various types of human cancer,and its upregulation triggers evasion of cellular apoptosis,metastasis,and invasion in cancer(Emdad at al.,2016;Dhiman et al.,2019).AEG-1 can promote tumor progression via multiple phosphoinositide 3-kinase(PI3K)/protein kinase B(Akt)pathways,contributing to an invasive phenotype and angiogenesis(Emdad at al.,2016;Dhiman et al.,2019).In addition,there is evidence for a functional link between AEG-1 and pro-survival mechanisms in various cancers(Dhiman et al.,2019),suggesting that AEG-1 is a key molecule for oncogenic events in cancer.

关键词： elevated al. invasion

Ultrasonographic identification of lateral femoral cutaneous nerve anatomical variation in persistent meralgia paresthetica:A case report

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World Journal of Clinical Cases 2023年第31期11卷 7699-7705页

作者： Hyeong-Woo Park Kyung-Suk Ji Jun-Hyung kim Li-Na kim Kang-Wook ha Department of Physical Medicine and Rehabilitation Sahmyook Medical CenterSeoul 02500South Korea Department of Obstetrics and Gynecology Sahmyook Medical CenterSeoul 02500South Korea

BACKGROUND Meralgia paresthetica(MP)is an entrapment mononeuropathy of the lateral femoral cutaneous nerve(LFCN).Although structural abnormalities in nerve tissues can be confirmed using ultrasonography,this is not routinely *** SUMMARY Herein,we present the case of a 52-year-old woman who developed MP after laparoscopic gynecological *** patient was referred to our clinic from an obstetrics and gynecology clinic with symptoms of numbness and a tingling sensation in the left anterolateral thigh,which developed after surgery performed 5 mo *** were performed to assess the disease status and determine the underlying *** examination revealed an anatomical variation,where the left LFCN was entrapped within the inguinal *** case suggests that performing ultrasonographic examination before and after surgery in the lithotomy position could help prevent *** This case demonstrates the value of ultrasonography in detecting anatomical variation and diagnosing persistent *** should be considered an adjunct to electromyography for optimal MP ***,this case would help other clinicians determine patient prognosis and decide on targeted treatment strategies.

关键词： Lateral femoral cutaneous nerve Anatomical variation Meralgia paresthetica Lithotomy position Ultrasonography Case report

Study on the Relationship between Mental Health Literacy and Psychological Symptoms of University Students: Mediating Effect of Grit

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International Journal of Mental Health Promotion 2023年第7期25卷 813-821页

作者： Yeo-Won Jeong Jung-ha kim Hyun-Kyeong Park Department of Nursing College of Nursing Dongguk UniversityGyeongju-si38066Korea Aeromedical Center of Korean Air Seoul07505Korea Department of Nursing Graduate SchoolDongguk UniversityGyeongju-si38066Korea

Background:The occurrence of mental health symptoms is higher in individuals aged between 18 and 24 years than in other age *** health literacy is derived from health literacy,and focuses on the knowledge,attitudes,and competencies that individuals need to acquire to manage their own health *** mental health literacy is associated with poorer mental *** is also a known protective factor against mental *** a heightened focus on mental health literacy and grit as important factors for decreasing mental health symptoms,knowledge of the effect of mental health literacy and grit on mental health symptoms is very *** study aimed to evaluate the relationship between mental health literacy and psychological symptoms and the mediating effect of grit on these ***:This cross-sectional descriptive study used survey data from 178 university students in *** were collected between March and May *** SPSS PROCESS macro(Model 4)was used to analyze the ***:Mental health literacy was not directly associated with psychological ***,an indirect pathway was observed between mental health literacy,depression,and anxiety,through ***:Mental health literacy affects psychological symptoms through ***,to improve the mental health of university students,it is necessary to develop programs that increase mental health literacy and grit.

关键词： Depression anxiety psychological stress health literacy mental health students

Effects of naringin, a flavanone glycoside in grapefruits and citrus fruits, on the nigrostriatal dopaminergic projection in the adult brain

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Neural Regeneration Research 2014年第16期9卷 1514-1517页

作者： Un Ju Jung Sang ryong kim Center for Food and Nutritional Genomics Research Kyungpook National University School of Life Sciences Kyungpook National University BK21 plus KNU Creative BioResearch Group Kyungpook National University Institute of Life Science & Biotechnology Kyungpook National University Brain Science and Engineering Institute Kyungpook National University

Recently, we have demonstrated the ability of naringin, a well-known flavanone glycoside of grapefruits and citrus fruits, to prevent neurodegeneration in a neurotoxin model of Parkinson＇s disease. Intraperitoneal injection of naringin protected the nigrostriatal dopaminergic projection by increasing glial cell line-derived neurotrophic factor expression and decreasing the level of tumor necrosis factor-alpha in dopaminergic neurons and microglia, respectively. These results suggest that naringin can impart to the adult dopaminergic neurons the ability to produce glial cell line-derived neurotrophic factor against Parkinson＇s disease with anti-inflammatory effects. Based on these results, we would like to describe an important perspective on its possibility as a therapeutic agent for Parkinson＇s disease.

关键词： naringin parkinson's disease GDNF inflammation mTORCI neurodegeneration

Comparative detection of syndecan-2 methylation in preoperative and postoperative stool DNA in patients with colorectal cancer

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世界胃肠外科杂志:英文版(电子版) 2023年第9期15卷 2032-2041页

作者： Ji Hyeong Song Tae Jeong Oh Sungwhan An Kyung ha Lee Ji Yeon kim Jin Soo kim Department of Surgery Chungnam National University Sejong HospitalSejong 30099South Korea Genomictree Inc.Daejeon 34027South Korea Department of Surgery College of MedicineChungnam National UniversityDaejeon 35015South Korea

BACKGROUND Early detection of colorectal cancer(CRC)is essential to reduce cancer-related morbidity and *** DNA(sDNA)testing is an emerging method for early CRC ***-2(SDC2)methylation is a potential biomarker for the sDNA *** DNA methylation is an early epigenetic event during tumorigenesis and can occur in the normal colonic mucosa during aging,which can compromise the sDNA test *** In this prospective study,we enrolled 151 patients with CRC who underwent curative surgical resection between September 2016 and May *** stool samples were collected from 123 patients and postoperative samples were collected from 122 patients.A total of 104 samples were collected from both preoperative and postoperative *** promoter methylation of SDC2 in sDNA was assessed using linear target enrichment quantitative methylation-specific real-time polymerase chain *** parameters were analyzed using the results of SDC2 *** Detection rates of SDC2 methylation in the preoperative and postoperative stool samples were 88.6%and 19.7%,*** tumor size(3 cm,P=0.019)and advanced T stage(T3–T4,P=0.033)were positively associated with the detection rate of SDC2 methylation before *** sex was associated with false positives after surgery(P=0.030).Cycle threshold(CT)values were significantly decreased postoperatively compared with preoperative values(Phat the SDC2 methylation test for sDNA has acceptable sensitivity and ***,small size and early T stage tumors are associated with a low detection rate of SDC2 *** the cycle threshold values significantly decreased after surgery,SDC2 methylation test for sDNA might have a diagnostic value for CRC.

关键词： Biomarkers DNA methylation Syndecan-2 Colorectal cancer

Defect engineering of ternary Cu-In-Se quantum dots for boosting photoelectrochemical hydrogen generation

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Carbon Energy 2023年第12期5卷 215-228页

作者： Shi Li Sung-Mok Jung Wookjin Chung Joo-Won Seo Hwapyong kim Soo Ik Park Hyo Cheol Lee Ji Su han Seung Beom ha In Young kim Su-Il In Jae-Yup kim Jiwoong Yang Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Chemical Engineering Dankook UniversityYonginRepublic of Korea Department of Chemistry and Nanoscience College of Natural ScienceEwha Womans UniversitySeoulRepublic of Korea Energy Science and Engineering Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea

Heavy-metal-free ternary Cu–In–Se quantum dots(CISe QDs)are promising for solar fuel production because of their low toxicity,tunable band gap,and high light absorption *** defects significantly affect the photophysical properties of QDs,the influence on photoelectrochemical hydrogen production is not well ***,we present the defect engineering of CISe QDs for efficient solar-energy *** acid–base reactions between metal halide–oleylamine complexes and oleylammonium selenocarbamate are modulated to achieve CISe QDs with the controlled amount of Cu vacancies without changing their *** them,CISe QDs with In/Cu=1.55 show the most outstanding photoelectrochemical hydrogen generation with excellent photocurrent density of up to 10.7 mA cm-2(at 0.6 VRHE),attributed to the suitable electronic band structures and enhanced carrier concentrations/lifetimes of the *** proposed method,which can effectively control the defects in heavy-metal-free ternary QDs,offers a deeper understanding of the effects of the defects and provides a practical approach to enhance photoelectrochemical hydrogen generation.

关键词： copper-indium-selenide defect engineering photoelectrochemical hydrogen generation quantum dots solar hydrogen

Propulsive Velocity Optimization of 3-Joint Fish Robot Using Genetic-Hill Climbing Algorithm

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Journal of Bionic Engineering 2009年第4期6卷 415-429页

作者： Tuong Quan Vo Hyoung Seok kim Byung ryong Lee School of Mechanical and Automotive Engineering University of UlsanSan 29Muger 2-dongNam-guUlsan 680-749Korea

Underwater robot is a new research field which is emerging quickly in recent *** researches in this field focus on Remotely Operated Vehicles(ROVs),Autonomous Underwater Vehicles(AUVs),underwater manipulators,*** robot, which is a new type of underwater biomimetic robot,has attracted great attention because of its silence in moving and energy efficiency compared to conventional propeller-oriented propulsive mechanism. However,most of researches on fish robots have been carried out via empirical or experimental approaches,not based on dynamic *** this paper,we proposed an analytical optimization approach which can guarantee the maximum propulsive velocity of fish robot in the given parametric ***,a dynamic model of 3-joint(4 links)carangiform fish robot is derived,using which the influences of parameters of input torque functions,such as amplitude,frequency and phase difference,on its velocity are investigated by ***,the maximum velocity of the fish robot is optimized by combining Genetic Algorithm(GA)and Hill Climbing Algorithm(HCA).GA is used to generate the initial optimal parameters of the input functions of the ***,the parameters are optimized again by HCA to ensure that the final set of parameters is the'near'global ***,both simulations and primitive experiments are carried out to prove the feasibility of the proposed method.

关键词： fish robot carangiform velocity optimization propulsive model

Effectiveness of out-fracture of the inferior turbinate with reduction nasal bone fracture

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世界临床病例杂志 2023年第27期11卷 6374-6382页

作者： Se-Young kim ha-Jong Nam Je-Yeon Byeon Hwan Jun Choi Department of Plastic and Reconstructive Surgery Soonchunhyang University Gumi HospitalGumi-si 39371South Korea Department of Plastic and Reconstructive Surgery Soonchunhyang University Cheonan HospitalCheonan-si 31151South Korea

BACKGROUND The nasal bone,being the most protruding bone in the center of the facial bones,is particularly susceptible to *** bone fractures can often result in secondary deformation and dysfunction of the nose,including septal *** on functional or intra-nasal complications have been rarely reported after nasal bone fracture *** To evaluate the severity of nasal obstruction and its improvement following nasal bone fracture reduction using inferior *** We conducted a retrospective review of data from 50 patients with symptomatic nasal obstruction between January to December *** patients underwent preoperative Computed tomography evaluation,and symptom changes and nasal cavity volume were analyzed using a visual analog scale and acoustic rhinometry before and after *** reduction and out-fracture of both inferior turbinates performed by the same *** outcomes were assessed by comparing changes in the nasal airway volume measured using acoustic rhinometry before and after *** minimal cross-sectional area(MCA)was also analyzed based on the Stranc *** Before reduction,the mean MCA for all cases was 0.59±0.06 cm^(2),which represented an 11%decrease compared to the average size of a Korean adult(0.65±0.03 cm^(2)).The MCA for frontal impact was 0.60±0.02 cm^(2) and for lateral impact,it was 0.58±0.03 cm^(2).After reduction via inferior turbinoplasty,the MCA improved to 0.64±0.04 cm^(2).CONCLUSION This study suggests that turbinoplasty is helpful in addressing nasal ***-fracture of the inferior turbinate is an effective and durable technique that can be easily performed to enlarge the nasal airway with minimal morbidity.

关键词： Acoustic rhinometry Nasal bone Fracture Turbinate