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Capacity Controllable Location Map Free Reversible Watermarking

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Chinese Journal of Electronics 2015年第3期24卷 518-523页

作者： HUANG Yuhsiu KUO Juiming hsieh Wenshyong Department of Computer Science and Engineering National Sun Yat-sen University Department of Computer Science and Information Engineering Cheng Shiu University Department of Computer and Communication Shu-Te University

Reversible watermarking techniques enable the extraction of the embedding bits from a watermarked image in a lossless way. It exploits the high spatial correlation among neighboring pixels. Application in reversible watermarking includes military and medical images. Images occurs overflow or underflow problems during the imbedding process since pixels value may be out of range [0:255]. Most methods require a location map to solve such problems. A location map free reversible watermarking algorithm is proposed in this study. A prediction threshold value is computed, histogram shifting scheme based on the prediction threshold value to solve overflow and underflow problems. Another threshold value is adopted to achieve capacity control, image quality is better in different payload length with this control. The experimental results reveal that the performance of proposed method outperforms that proposed by FUJIYOSHI et al.

关键词： Reversible watermarking Capacity control Predicted value Histogram shifting

Kinetics of electroless Ni-Cu-P deposits on silicon in a basic hypophosphite-type bath

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International Journal of Minerals,Metallurgy and Materials 2009年第2期16卷 197-202页

作者： Shu-Huei hsieh Wen-Jauh Chen Department of Materials Science and Engineering Formosa UniversityHuweiYunlin 632China Taipei Graduate School of Materials Science Yunlin University of Science and TechnologyYunlin 640China Taipei

Electroless Ni-Cu-P deposits were deposited on the Si substrate in a basic hypophosphite-type plating bath. The effects of pH value and the metal source composition,Ni and Cu,in the plating bath on the kinetics of the Ni-Cu-P deposition were studied. The electroless Ni-Cu-P deposits were characterized by a scanning electron microscope,a transmission electron microscope,an energy dispersive X-ray spectroscope,and an X-ray diffractometer. The results showed that the pH value of the plating bath had no ob-vious effect on the morphology and composition of electroless Ni-Cu-P deposits. However,the composition of the metal source,Ni and Cu,in the plating bath had great effect on the kinetics of electroless Ni-Cu-P deposition.

关键词： electroless deposition Ni-Cu-P silicon substrate kinetics activation energy

Exploratory analysis of grocery product networks

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Journal of Management Analytics 2022年第2期9卷 169-184页

作者： Ping-Hung hsieh College of Business Oregon State UniversityCorvallisOR 97331USA

Finding meaningful sets of co-purchased products allows retailers to manageinventory better and develop market strategies. Analyzing the baskets ofproducts, known as market basket analysis, is typically carried out usingassociation rule mining or community detection approach. This article usesboth methods to investigate a transaction dataset collected from a brick-andmortargrocery store. The findings reveal interesting purchasing patterns oflocal residents and prompt us to consider dynamic modeling of the productnetwork in the future.

关键词： market basket analysis association rules community detection graph theory social networks transaction data

A new weir surface repair layer with shock absorbing cushion design

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Earthquake Engineering and Engineering Vibration 2013年第3期12卷 487-496页

作者： Tse-Shan Hsu Yi-Lang hsieh Department of Civil Engineering Feng-Chia University Ph.D Program in Civil and Hydraulic Engineering Feng-Chia University

A shock absorbing cushion has never been introduced into any traditional weir surface repair layer design. However, shocks induced by high discharge with heavy sediment can easily produce brittle fracture and peeling over a weir surthce repair layer as it is impacted by floods accompanied by particles of different sizes. In this study, transcending traditional designs, the authors developed a composite unit designed with a shock absorbing cushion that has performed well during field tests, proving that the weir body can be effectively protected even if the composite units are directly laid on a severely uneven weir surface repair layer.

关键词： shock absorbing cushion brittle fracture peeling weir

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Dengue outbreaks in Taiwan, 1998-2017: Importation, serotype and temporal pattern

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Asian Pacific Journal of Tropical Medicine 2018年第8期11卷 460-466页

作者： Ying-Hen hsieh Department of Public Health China Medical University

Objective: To ascertain the role of imported cases and serotypes on dengue outbreaks in Taiwan which have been sporadic yet highly volatile during the past two decades, exhibiting record-breaking magnitude in recent years. Methods: Confirmed case and serotype data from Taiwan Centers for Disease Control during 1998-2017 were fully examined, with fitting of weekly and daily case data of each city/county to a mathematical model to pinpoint the waves of cases and their locations. Moreover, we quantify the timing of turning point and transmission potential of each wave and determine its circulating serotype, to ascertain any pattern or connection between the variations in circulating serotypes and the magnitude/transmissibility of outbreak. Results: While the number of imported case increased steadily during past two decades, the yearly number of indigenous cases fluctuated wildly. Moreover, while yearly percentages of serotypes for imported cases remains steady, that of indigenous cases does not exhibit any clear pattern. There was at least one wave of reported cases somewhere in Taiwan every year from 1998 to 2015, except in 2016-2017. The effective reproduction number R for all waves in all locations ranged from 1.14 to 2.87, with the exception of two Tainan waves, in 2010(3.95) and 2015(6.84). Four major outbreaks of over 2000 cases reveal circulation of one dominant serotype. Conclusions: Correlation between imported cases and indigenous outbreak prove to be difficult to ascertain, even with the availability of serotype data. However, although there had been occasional co-circulation of serotypes in one location, and for some years with different serotypes circulating in different locations, all major outbreaks of over 2 000 cases during the past two decades are due to circulation of mainly a single serotype, perhaps indicating greater transmission potential with one dominating serotype.

关键词： DENV Serotype Taiwan Imported cases Mathematical model Reproduction number

Co-infection of SENV-D among chronic hepatitis C patients treated with combination therapy with high-dose interferon-alfa and ribavirin

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World Journal of Gastroenterology 2005年第27期11卷 4241-4245页

作者： Chia-Yen Dai Wan-Long Chuang Wen-Yu Chang Shinn-Chemg Chen Li-Po Lee Ming-Yen hsieh Nei-Jen Hou Zu-Yau Un Ming-Yuh hsieh liang-Yen Wang Ming-Lung Yu Hepatobiliary Division Department of Internal MedicineKaohsiung Medical University Hospital Kaohsiung Taiwan China Department of Internal Medicine Kaohsiung Municipal Hsiao-Kang Hospital Kaohsiung TaiwanChina Department of Occupational Medicine Kaohsiung Municipal Hsiao-Kang Hospital Kaohsiung Taiwan China

AIM： The clinical significance of co-infection of SENV-D among patients with chronic hepatitis C （CHC） and response of both viruses to combination therapy with high-dose interferon-alfa （IFN） plus ribavirin remain uncertain and are being ***： Total 164 （97 males and 67 females, the mean age 48.1＋11.4 years, range： 20-73 years, 128 histologically proved） naive CHC patients were enrolled in this study. SENV-D DNA was tested by PCR *** of serum HCV RNA was performed using a standardized automated qualitative RT-PCR assay （COBAS AMPLICOR HCV Test, version 2.0）. HCV genotypes la,lb, 2a, 2b, and 3a were determined by using genotypespecific primers. Pretreatment HCV RNA levels were determined by using the branched DNA assay （Quantiplex HCV RNA 3.0）. There are 156 patients receiving combination therapy with IFN 6 MU plus ribavirin for 24 wk and the response to therapy is ***： Sixty-one （37.2%） patients were positive for SENV-D DNA and had higher mean age than those who were negative （50.7＋ 10.6 years vs 46.6＋ 11.6 years,P = 0.026）. The rate of sustained viral response （SVR） for HCV and SENV-D were 67.3% （105/156） and 56.3% （27/48）, respectively. By univariate analysis, the higher rate of SVR was significantly related to HCV genotype non-1b （P〈0.001）, younger ages （P = 0.014）, lower pretreatment levels of HCV RNA （P = 0.019） and higher histological activity index （HAI） score for intralobular regeneration and focal necrosis （P= 0.037）. By multivariate analyses, HCV genotype non-lb, younger age and lower pretreatment HCV RNA levels were significantly associated with HCV SVR （odds ratio （OR）/95% confidence interval （CI）： 12.098/0.02-0.19, 0.936/0.890-0.998, and 3.131/1.080-9.077, respectively）. The SVR of SENV-D was higher among patients clearing SENV-D than those who had viremia at the end of therapy （P = 0.04）.CONCLUSION： Coexistent SENV-D infection, apparently associated with higher ages, is found in more than onethird Taiwan Resi

关键词： Chronic hepatitis C Combination therapy Interferon Ribavirin SENV-D

Botulinum toxin injection for Cockayne syndrome with muscle spasticity over bilateral lower limbs:A case report

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World Journal of Clinical Cases 2021年第18期9卷 4728-4733页

作者： Lin-Chieh Hsu Po-Ying Chiang Wei-Pin Lin Yao-Hong Guo Pei-Chun hsieh Ta-Shen Kuan Wei-Chih Lien Yu-ching Lin Department of Physical Medicine and Rehabilitation National Cheng Kung University HospitalCollege of MedicineNational Cheng Kung UniversityTainan 704Taiwan Department of Physical Medicine and Rehabilitation College of MedicineNational Cheng Kung UniversityTainan 704Taiwan Medical Device Innovation Center National Cheng Kung UniversityTainan 704Taiwan

BACKGROUND Cockayne syndrome(CS)is a rare inherited disease characterized by progressive motor symptoms including muscle weakness,joint contracture,ataxia,and *** neurotoxin type A has been used for conditions such as dystonia and spasticity,but it has rarely been used in patients with *** SUMMARY We report a 6-year-and-9-mo old girl diagnosed with CS who received an injection of botulinum neurotoxin type A to manage her difficulty with walking.A total dose of 210 units of botulinum neurotoxin type A was administered into the bilateral tibialis posterior and gastrocnemius *** evaluate the treatment effects on spasticity,joint contracture,pain,and ataxia,measurement tools including the Modified Ashworth Scale,the passive range of motion,the Faces Pain Scale-Revised,and the Scale for the Assessment and Rating of Ataxia,were *** first week after the injection,the Modified Ashworth Scale score for the plantar flexors and foot invertors improved bilaterally,along with advancements in the passive range of motion of the bilateral ankles and a lower score for the Faces Pain *** treatment effects persisted to the 8th week post-injection,but returned to baseline values at the 12th week post-injection,except for the pain *** Botulinum toxin injection can thus be considered as a treatment option for lower extremity spasticity,joint contracture,and pain derived from CS.

关键词： Cockayne syndrome Botulinum toxin Spasticity Pain Ataxia Case report

Image Reconstructions from Limit Views and Angle Coverage Data for a Stationary Multi-Pinhole SPECT System

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Tsinghua Science and Technology 2010年第1期15卷 44-49页

作者： hsieh Hohui HSIAO Ingtsung Department of Medical Imaging and Radiological Sciences Chang Gung UniversityTaoyuan 333 Molecular Imaging Center Chang Gung Memorial HospitalTaoyuan 333

The goal of this paper is to investigate different reconstruction methods for solving the limited angle problem in reconstructing the projection data from a stationary multi-pinhole system based on a three-head clinical single photon emission computed tomography （SPECT） camera. Three iterative recon- struction approaches were studied including maximum likelihood expectation maximization （MLEM）, maximum a posteriori expectation maximization （MAPEM） with a smoothing prior, and an alternating optimization schemes from MLEM and total variation （TV） optimization. A three-headed multipinhole SPECT was simulated with apertures of nine 1-mm pinholes each, and covered scanning volume of 6-mm diameter. The reconstructions were optimized for various iterations based on visual inspections, and finally 20 iterations were applied for each method. For both MLEM-TV and MAPEM-TV, various initial reconstructions before TV optimization were studied. The smoothing parameter for MAPEM and the gradient descent constant for TV were also investigated through visual comparison. The preliminary results showed the 3 reconstruction methods generated compatible images, and can restore the images from projection data suffering limited angular sampling. However, MLEM was noisy for low-count and highly limited angle data, and thus suitable smoothing in MAPEM alleviated this problem, initial reconstructions were necessary for better edge enhancement in TV. The conclusion is that TV might be potential in producing more edge-enhanced images if all parameters were optimized.

关键词： multipinhole single photon emission computed tomography (SPECT) iterative reconstruction total variation (TV) optimization

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PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer

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中国肺癌杂志 2015年第6期18卷 345-350页

作者： Yang WANG Zhidong XU Jian-Hua MAO David.hsieh Alfred AU David M. JABLONS Hui LI liang YOU Thoracic Surgery Department Beijing Chao-Yang Hospital Capital University of Medical Science Thoracic Oncology Laboratory Department of Surgery Comprehensive Cancer Center University of California Life Sciences Division Lawrence Berkeley National Laboratory University of California Division of Diagnostic Pathology Comprehensive Cancer Center University of California

Background and objective Maintenance of genomic integrity is essential to ensure normal organismal development and to prevent diseases such as ***-Set7(also known as Set8)is a cell cycle regulated enzyme that catalyses monomethylation of histone 4 at Lys20(H4K20me1)to promote chromosome condensation and prevent DNA *** studies show that CRL4CDT2-mediated ubiquitylation of PR-Set7 leads to its degradation during S phase and after DNA *** might occur to ensure appropriate changes in chromosome structure during the cell cycle or to preserve genome integrity after DNA *** We developed a new model of lung tumor development in mice harboring a conditionally expressed allele of *** have therefore used a mouse model to demonstrate for the first time that Cul4A is oncogenic in *** this model,staining of PR-Set7 in the preneoplastic and tumor lesions in Adeno Cre-induced mouse lungs was *** we identified higher protein level changes ofγ-tubulin and pericentrin by *** The level of PR-Set7 down-regulated in the preneoplastic and adenocarcinomous lesions following over-expression of *** also identified higher levels of the proteins pericentrin andγ-tubulin in Cul4A mouse lungs induced by Adeno *** PR-Set7 is a direct target of Cul4A for degradation and involved in the formation of lung tumors in the conditional Cul4A transgenic mouse model.

关键词：临床诊断医学肺疾病

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