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Spatiotemporal characteristics and influencing factors of vegetation water use efficiency on the Tibetan Plateau in 2001–2020

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Journal of Geographical Sciences 2025年第1期35卷 39-64页

作者： HE Chenyang WANG Yanjiao YAN Feng LU qi School of Ecological and Environmental Science East China Normal University Institute of Ecological Conservation and Restoration Chinese Academy of Forestry National Climate Center China Meteorological Administration

Water use efficiency （WUE）,as a pivotal indicator of the coupling degree within the carbon–water cycle of ecosystems,holds considerable importance in assessment of the carbon–water balance within terrestrial ***,in the context of global warming,WUE evolution and its primary drivers on the Tibetan Plateau remain *** study employed the ensemble empirical mode decomposition method and the random forest algorithm to decipher the nonlinear trends and drivers of WUE on the Tibetan Plateau in 2001–*** indicated an annual mean WUE of 0.8088 gC/mm·m2across the plateau,with a spatial gradient reflecting decrease from the southeast toward the *** manifesting monotonous trends of increase or decrease in WUE accounted for 23.64%and 9.69%of the total,***,66.67%of the region exhibited trend reversals,i.e.,39.94%of the area of the Tibetan Plateau showed transition from a trend of increase to a trend of decrease,and 26.73%of the area demonstrated a shift from a trend of decrease to a trend of *** factors accounted for 70.79%of the variability in *** leaf area index and temperature served as the major driving forces of WUE variation.

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The effect of low fluoride concentrations on microdamage accumulation in mouse tibias under impact loading

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Acta Mechanica Sinica 2015年第6期31卷 944-951页

作者： qing Luo Nan Chen Yan-Heng Zhou qi-guo rong Department of Orthodontics Peking University School and Hospital of Stomatology College of Engineering Peking University

Microdamage accumulation in bone is one of the mechanisms for energy dissipation during the fracture process. Changes in the ultrastructure and composition of bone constituents due to aging or diseases could affect microdamage accumulation. Low concentration （1 mM） of sodium fluoride （NaF） has been used in this study to investigate the effect of ultrastructural changes on microdamage accumu- lation in mouse tibias following free-fall impact loadings. Twenty-two tibias were divided randomly into control and NaF-treated groups. Free-fall impact loading was conducted twice on each tibia to produce microdamage. The elas- tic modulus of NaF-treated tibias decreased significantly after the impact loadings, while there was no significant difference in the modulus of untreated samples between pre- and post-damage loadings. Microdamage morphology analysis showed that less and shorter microcracks existed in NaF-treated tibias compared with control bones. Meanwhile, more and longer microcracks were observed in tensile regions in untreated samples compared with that in compressive regions, whereas no significant difference was observed between tensile and compressive regions in NaF-treated bones. The results of this study indicate that more energy is required to generate microcracks in NaF-treated bone than in normal bone. A low concentration of fluoride treatment may increase the toughness of bone under impact loading.

关键词： Microdamage accumulation · Fluoridetreatment · Ultrastructural changes · Free-fall impact

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4个木薯优良品种在怒江干热河谷的试种初报

广东农业科学 2010年第1期37卷 30-32页

作者：刘倩刘光华张林辉王跃全程金焕郭容琦云南省农科院热带亚热带经济作物研究所云南保山678025

对引进的4个木薯品种[KU50(Ⅱ)(由泰国引进)、南植188、华南7号、华南205]在怒江干热河谷的适应性作了研究,结果表明:南植188的多项地上部分生物量测定值是4个品种中最优的,地下部分的平均单株鲜薯重量及每667 m2理论产量比其他3品种更... 详细信息

对引进的4个木薯品种[KU50(Ⅱ)(由泰国引进)、南植188、华南7号、华南205]在怒江干热河谷的适应性作了研究,结果表明:南植188的多项地上部分生物量测定值是4个品种中最优的,地下部分的平均单株鲜薯重量及每667 m2理论产量比其他3品种更高。KU50(Ⅱ)的分枝数、鲜薯个数最多,干物率最大,鲜薯淀粉含量最高而且氢氰酸含量最低;而华南205的干片淀粉含量最高;华南7号理论产量居第2位。南植188最适合在怒江干热河谷种植,KU50(Ⅱ)与华南205深加工的经济效益相对较高,具有较高的推广价值,华南7号推广价值一般。

关键词：木薯品种试种适应性

MicroRNA-155/FOXO3a在心脏手术后心房颤动患者心房组织中的表达及与心房纤维化的关系

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中国现代医学杂志 2020年第8期30卷 40-44页

作者：冶敦清祁国荣路霖王黎明青海省心脑血管病专科医院心外科青海西宁810000

目的探讨microRNA-155/叉头框蛋白O 3a(miR-155s/FOXO3a)在心脏手术后心房颤动(以下简称房颤)患者心房组织中的表达情况,及其与心房纤维化的关系。方法选取2018年2月—2019年4月青海省心脑血管病专科医院收治的风湿性心脏瓣膜病并行心... 详细信息

目的探讨microRNA-155/叉头框蛋白O 3a(miR-155s/FOXO3a)在心脏手术后心房颤动(以下简称房颤)患者心房组织中的表达情况,及其与心房纤维化的关系。方法选取2018年2月—2019年4月青海省心脑血管病专科医院收治的风湿性心脏瓣膜病并行心脏手术治疗的患者92例。根据患者病史、心电图及24 h动态心电图检查结果分为房颤组和窦性心律组。于心脏手术中采集患者右心房组织,采用qRTPCR检测心房组织中miR-155、FOXO3a mRNA相对表达量;采用免疫印迹法检测心房组织中FOXO3a和p-FOXO3a蛋白相对表达量;采用Masson染色法及计算机成像分析系统计算心房组织胶原容积分数,评价心房组织纤维化程度;采用Pearson法分析心房组织miR-155、p-FOXO3a蛋白水平与心房纤维化程度的相关性。结果房颤组左心房内径、右心房内径高于窦性心律组(P<0.05)。房颤组胶原容积分数较窦性心律组高(P<0.05)。窦性心律组miR-155 mRNA相对表达量低于房颤组(P<0.05),FOXO3a mRNA相对表达量高于房颤组(P<0.05)。房颤组p-FOXO3a蛋白相对表达量低于窦性心律组(P<0.05)。房颤组患者心房组织miR-155水平与p-FOXO3a蛋白水平呈负相关(r=-0.485,P<0.05),与胶原容积分数呈正相关(r=0.490,P<0.05),心房组织p-FOXO3a蛋白水平与胶原容积分数呈负相关(r=-0.471,P<0.05)。结论心脏手术后房颤患者心房组织中miR-155高表达,p-FOXO3a蛋白低表达,均与心房纤维化有关,共同影响房颤的发生与维持。

关键词：心房颤动 miR-155 叉头框蛋白O 3a 心房组织纤维化

A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2025年第2期20卷 503-517页

作者： qi Liu Jianye Xie Runxue Zhou Jin Deng Weihong Nie Shuwei Sun Haiping Wang Chunying Shi Department of Human Anatomy Histology and EmbryologySchool of Basic MedicineQingdao UniversityQingdaoShandong ProvinceChina Department of Neurology The Affiliated Hospital of Qingdao UniversityQingdaoShandong ProvinceChina Department of General Practice The Affiliated Hospital of Qingdao UniversityQingdaoShandong ProvinceChina

Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic ***,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in ***,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic *** metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ***,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel ***-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in *** results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor *** findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury.

关键词： angiogenesis biomaterial blood-brain barrier cerebral ischemia/reperfusion injury control release drug delivery inflammation QK peptides matrix metalloproteinase-2 neuroprotection self-assembling nanofiber hydrogel

Therapeutic and recurrence-preventing effects of qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer

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Asian Pacific Journal of Tropical Medicine 2016年第1期9卷 79-83页

作者： guo-rong Jiang Hui-Nan Ge guo-qiang Liang Liang Zhou Lu-rong Zhang Suzhou Academy of Wumen Chinese Medicine Suzhou Hospital of Traditional Chinese Medicine

Objective:To explore the therapeutic and recurrence-preventing effects of qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ***:A total of 138 SD rats were selected to make rat models with gastric ulcer induced by acetic acid(24 rats with sham operation served as sham operation group),and were randomly divided into model group(n=30),western medicine group(n=30),traditional Chinese medicine(TCM) group(n=24) and combination group(combined western medicine and TCM group,n=30).Western medicine group was gavaged with omeprazole in the morning and with iso-volumetric distilled water in the afternoon;TCM group and TCM sham operation group were gavaged with iso-volumetric distilled water in the morning and with qi-Replenishing and Blood-Activating Formula in the afternoon;combination group was gavaged with omeprazole in the morning and with qi-Replenishing and Blood-Activating Formula in the afternoon;sham operation group and model group were gavaged with iso-volumetric distilled water both in the morning and *** indexes and degree of mucosal degree in rats at different time points after gavage were *** days after gavage,interleukin(IL)-1β was given to induce ulcer recurrence so as to observe the recurrent severity and rate of ulcer in each ***:Compared with model group and western medicine group,treatment in combination group could prominently reduce the ulcer index of rats with peptic ulcer,and increase the healing rate and inhibition rate of peptic *** IL-1β-induced ulcer recurrence,combination group was significantly superior to model group and western medicine group in ulcer recurrent rate[50%(3/6) vs.100%(6/6)]and ***:Basic acid-suppression therapy combined with qi-Replenishing and BloodActivating Formula can effectually improve the ulcer healing quality and reduce ulcer recurrence.

关键词： qi-Replenishing and Blood-Activating Formula Gastric ulcer Recurrence prevention Ulcer index Damage severity

Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 763-778页

作者： Minghuang Gao Xinyue Wang Shijie Su Weicheng Feng Yaona Lai Kongli Huang Dandan Cao qi Wang Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina Institute of Clinical Pharmacology Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina The Sixth Affiliated Hospital Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to antigen delivery and immune cell activation. The advent of novel genomic technologies has enabled rapid progress in the characterization of myeloid and lymphoid cells and their interactions with meningeal lymphatic vessels within the central nervous system. In this review, we provide an overview of the multifaceted roles of meningeal lymphatic vessels within the context of the central nervous system immune network, highlighting recent discoveries on the immunological niche provided by meningeal lymphatic vessels. Furthermore, we delve into the mechanisms of crosstalk between meningeal lymphatic vessels and immune cells in the central nervous system under both homeostatic conditions and neurodegenerative diseases, discussing how these interactions shape the pathological outcomes. Regulation of meningeal lymphatic vessel function and structure can influence lymphatic drainage, cerebrospinal fluid-borne immune modulators, and immune cell populations in aging and neurodegenerative disorders, thereby playing a key role in shaping meningeal and brain parenchyma immunity.

关键词： central nervous system meningeal lymphatic vessels immunity myeloid cells lymphatic cells neurodegenerative disease

大岗山毛竹林中主要树种生态位及DCA排序分析

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江西农业大学学报 2012年第6期34卷 1163-1170,1185页

作者：杨清培王兵郭起荣杨光耀赵广东余定坤宋庆妮江西农业大学/江西省竹子种质资源与利用重点实验室江西南昌330045 中国林业科学研究院森林生态环境与保护研究所北京100091 国家林业局国际竹藤中心北京100102

为探讨竹林中毛竹(Phyllostachys edulis)与木本植物间的生态位关系,主要采用Levins、MacArthur-Levins和Pearson等指数,对江西大岗山天然毛竹林中20个主要树种的生态位宽度、生态位重叠及种间相关性等生态特征进行了分析和DCA排序研究... 详细信息

为探讨竹林中毛竹(Phyllostachys edulis)与木本植物间的生态位关系,主要采用Levins、MacArthur-Levins和Pearson等指数,对江西大岗山天然毛竹林中20个主要树种的生态位宽度、生态位重叠及种间相关性等生态特征进行了分析和DCA排序研究。结果表明:毛竹是竹林中最强的优势种,其生态位最宽(BA=0.711),且对其他树种生态位重叠度较大(Oij>0.30),而其他多数树种对毛竹生态位重叠度则较小(Oji<0.25),说明它对其他树种具有较明显竞争优势。同时,竹林内种间负关联种对数占67.89%,大多树种间存在较大的生态异质性与资源利用差异性,它们可长期共存,形成较为稳定的竹木混交林,尤其是毛竹与丝栗栲、山乌桕、杉木等树种更易形成竹阔(杉)混交林。

关键词：毛竹林生态位 DCA排序大岗山

DcR3 and survivin are highly expressed in colorectal carcinoma and closely correlated to its clinicopathologic parameters

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第9期10卷 675-682页

作者： qi-lian LIANG Bi-rong WANG guo-hong LI Department of Medical Oncology Affiliated Hospital of Guangdong Medical College Zhanjiang 524001 China

Objective: To investigate the expression of death decoy receptor 3 (DcR3) and survivin in colorectal carcinoma. Methods: Tumor and normal tissues were taken from a total of 100 colorectal carcinoma patients during surgery, and the expression of DcR3 and survivin was examined by immunohistochemistry, Western blotting, and reverse transcription-polymerase chain reaction (RT-PCR) analyses. Results: RT-PCR showed that the expression levels of DcR3 mRNA (0.846±0.242, P<0.01) and survivin mRNA (0.7835±0.2392, P<0.01) in colorectal cancer tissues were significantly higher than those in adjacent normal tissues. Western blotting showed that the expression levels of DcR3 protein (0.795±0.261, P<0.01) and survivin protein (0.6765±0.1351, P<0.01) in tumor tissues were significantly higher than those in non-cancer tissues. The immunohistochemical streptavidin-peroxidase (SP) method showed that the positive expression rates of DcR3 and survivin were 67.0% and 58.0% in colorectal cancer tissues, and 18.0% and 3.0% in non-cancerous colorectal tissues (P<0.05), respectively. The positive correlations of DcR3 (P<0.01) and survivin (P<0.01) to the differentiation of colorectal carcinoma cells, lymph node metastasis, and patho-logical stage were observed. The expression of DcR3 and survivin was found to be positively correlated to clinicopathologic parameters of colorectal carcinoma. Conclusion: The overexpressed DcR3 and survivin in colorectal cancer may contribute to the development of the cancer. The monitoring of these two proteins may be useful for the diagnosis, differentiation, metastasis, and determination of stages of colorectal carcinoma.

关键词： Death decoy receptor 3 (DcR3) Survivin Colorectal carcinoma