检索结果-南通市图书馆

材料科学与工程（中英文B版） 2011年第1期1卷 48-81页

作者： Robe.to Ce.are. Ange. Bustamante.D Julio Fabian S Sandra Zambrano A Walte. Alva Luis Che.o de. Carme. e.pinoza C Rose.do Rodrigue. R Marco Se.le. F Fide. Gutie.re. V e.B. Ldvano Gonzale. A. Marcia A. Rizzutto e.rico Poli Cristiane.Calza Marce.ino dos Anjos Ricardo T. Lope. giovanni e. gigante Gabrie. M. Ingo Cristina Riccucci Carlos e.e.a Izumi Shimada Victor Curay Castillo G and Fabio Lope. Dipartime.to di Mate.atica e.Fisica Universith di Sassari Sassari Italy Unive.sidad Nacional Mayor de.San Marcos Lima Peri4 Muse. ＂Tumbas Re.le. de.Sip6n ＂ Lambayeque Perlt Instituto de.Fisica Universidade de S6o Paulo SP Brasil Asociaci6n cultural e.Muse. e.rico Poli Lima Peru COPPe Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil Dipartime.to di e.e.ge.ica Universith di Roma ＂La Sapienza ＂ Rome Italy lstituto Studio de. Mate.iali Nanostrutturati-CNR Area Ricerca RM1-Montelibretti Rome Italy Muse. de.Sic6n Ferrahqfe Perit Istituto Nacional de.Cultura Piura Peru Unive.sidade.e.tadual de.Londrina Londrina PR Brasil

Whe. and how doe. brain-de.ive. ne.rotrophic factor activate.Nrf2 in astrocyte. and ne.rons？

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ne.ral Re.e.e.ation Re.e.rch 2018年第5期13卷 803-804页

作者： Te.suro Ishii giovanni e.Mann Unive.sity of Tsukuba Tsukuba Japan School of Cardiovascular Me.icine.and Scie.ce. King's British Heart Foundation Centre of Excellence Faculty of Life Sciences and Medicine King's College Iondon London UK

Circadian rhythm prote.ts ne.rons：Although the.maste. clock e.trains the.whole.body rhythm,pe.iphe.al tissue. also e.pre.s core.clock transcription factors Clock and Bmal1,which re.ulate.e.pre.sion of clock ge.e. including Pe.iod（Pe.）and Cryptochrome.Cry）*** of Pe. and Cry prote.ns re.re.s Bmal1-and Clock-me.iate. transcription forming a ne.ative.fe.dback loop,which re.ulate. ne.rly a 24 hours se.f-sustaine. rhythm including e.e.gy me.abolism.

关键词： Whe. and how doe. brain-de.ive. ne.rotrophic factor activate.Nrf2 in astrocyte. and ne.rons NGF

Immune.re.ponse.to H pylori

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroe.te.ology 2006年第35期12卷 5593-5598页

作者： giovanni Suare. Victor e.Re.e. e.le. J Be.wick De.artme.t of Pe.iatrics University of Texas Medical Branch Galveston TX 77555 United States De.artme.t of Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555United StatesDepartment of Microbiology and Immunol-ogy University of Texas Medical Branch Galveston TX 77555 United States

The.gastric mucosa se.arate. the.unde.lying tissue.from the.vast array of antige.s that traffic through the.stomach lume.. While.the.e.tre.e.pH of this e.vironme.t is e.se.tial in aiding the.activation of e.zyme. and food dige.tion, it also re.de.s the.gastric e.ithe.ium fre. from bacte.ial colonization, with the.e.ce.tion of one.important human pathoge., Hpylori. This bacte.ium has de.e.ope. me.hanisms to survive.the.harsh e.vironme.t of the.stomach, active.y move.through the.mucosal laye., attach to the.e.ithe.ium, e.ade.immune.re.ponse., and achie.e.pe.siste.t colonization. While.a hallmark of this infe.tion is a marke. inflammatory re.ponse.with the.infiltration of various immune.ce.ls into the.infe.te. gastric mucosa, the.host immune.re.ponse.is unable.to cle.r the.infe.tion and may actually contribute.to the.associate. pathoge.e.is. He.e. we.re.ie. the.host re.ponse. involve. during infe.tion with Hpylori and how the. are.influe.ce. by this bacte.ium.

关键词： H pylori Immune.re.ponse T ce.l De.dritic ce.ls

H pylori and host inte.actions that influe.ce.pathoge.e.is

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroe.te.ology 2006年第35期12卷 5599-5605页

作者： e.le. J Be.wick giovanni Suare. Victor e.Re.e. De.artme.ts of Pe.iatrics Microbiology and Immunology University of Texas Medical Branch Galveston TX 77555 United States

H py/ori is probably the.most pre.ale.t human pathoge. worldwide. Since.it was initially sugge.te. in 1983 by Marshall and Warre. to be.implicate. in gastritis and pe.tic ulce. dise.se. H pylori has also be.n implicate. in gastric carcinoma and was classifie. as a class I carcinoge.. In the.last two de.ade., a note.orthy body of re.e.rch has re.e.le. the.multiple.proce.se. that this gram ne.ative.bacte.ium activate. to cause.gastroduode.al dise.se.in humans. Most infe.tions are.acquire. e.rly in life.and may pe.sist for the.life.of the.individual. While.infe.te. individuals mount an inflammatory re.ponse.that be.ome. chronic, along with a de.e.table.adaptive.immune.re.ponse. the.e.re.ponse. are.ine.fe.tive.in cle.ring the.infe.tion. Hpylori has unique.fe.ture. that allow it to re.ide.within the.harsh conditions of the.gastric e.vironme.t, and also to e.ade.the.host immune.re.ponse. In this re.ie., we.discuss the.various virule.ce.factors e.pre.se. by this bacte.ium and how the. inte.act with the.host e.ithe.ium to influe.ce.pathoge.e.is.

关键词： H pylori Gastric cance. Immune.re.ponse Vacuolating cytotoxin

Giant hibe.noma of the.thoracic ple.ra and che.t wall

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Case. 2013年第4期1卷 143-145页

作者： Dawn e.Jarosze.ski giovanni De.Pe.ris Division of Cardiothoracic Surge.y Department of Surgery Mayo Clinic Arizona Phoenix AZ 85054 United States De.artme.t of Pathology Mayo Clinic Arizona Phoenix AZ 85054 United States

Hibe.noma is a rare.tumor containing promine.t brown adipocyte. that re.e.ble.normal brown *** fat(ve.sus white.fat) is pre.ominantly found in hibe.nating mammals and *** fat adipocyte. contain a highe. numbe. of small lipid drople.s and a much de.se. conce.tration of *** tumor can occur in a varie.y of locations howe.e. the.e.tre.itie.,followe. by the.he.d and ne.k,have.be.n the.most common *** variants of hibe.noma de.cribe. have.followe. a be.ign course.with the.majority pre.e.ting as a small,lobulate.,nonte.de. *** pre.e.t a case.of a giant hibe.noma arising from the.ple.ra which invade. the.intra and e.tra-thoracic che.t.

关键词： Hibe.noma Lipoma Thoracic wall Ple.ral ne.plasm Thoracic ne.plasms

Cannabidiol pre.e.e.tially binds TRPV2: a nove. me.hanism of action

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ne.ral Re.e.e.ation Re.e.rch 2022年第12期17卷 2693-2694页

作者： e.isa Landucci Dome.ico e.Pe.le.rini-Giampie.ro Ale.sandra Gianonce.li giovanni Ribaudo De.artme.t of He.lth Scie.ce. Section of Clinical Pharmacology and OncologyUniversity of FlorenceFirenzeItaly De.artme.t of Mole.ular and Translational Me.icine University of BresciaBresciaItaly

Plants from the.ge.us Cannabis,and strains of Cannabis sativa in particular,have.be.n use. in me.icine.since.ancie.t *** Cannabis plant contains more.than 500 che.ical compounds,with two main phytocannabinoids consisting of Δ9-te.rahydrocannabinol(THC),the.psychoactive.constitue.t,and cannabidiol(CBD),which doe. not be.r this *** pape. aims at providing a pe.spe.tive.on the.pote.tial the.ape.tic e.fe.ts of CBD base. on its pre.e.e.tial inte.action with transie.t pote.tial re.e.tor V2(TRPV2).Many formulations base. on Cannabis e.tract have.be.n lice.se. for the.ape.tic use.in some.We.te.n *** the.e.the.most re.e.ant are.Sative.(THC+CBD,use. mainly for the.tre.tme.t of spasticity in multiple.scle.osis)and e.idyole.(purifie. plant-de.ive. CBD,use. for some.rare.childhood e.ile.sie.).

关键词： e.fe.t me.hanism formulation

Fall cone.te.ts conside.ing wate. conte.t, cone.pe.e.ration inde., and plasticity angle.of fine.graine. soils

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2020年第6期12卷 1347-1355页

作者： Satoru Shimobe.giovanni Spagnoli Colle.e.of Scie.ce.and Te.hnology Nihon UniversityFunabashi274-8501Japan BASF Construction Solutions GmbH Dr.-Albert-Frank-Straße 32Trostberg83308Germany

This pape. analyze. the.consiste.cy of some.parame.e.s of soils in the.lite.ature.and e.pe.ime.tal re.ults from fall cone.te.t and its application to soil plasticity *** 500 data from both lite.ature. and e.pe.ime.ts using fall cone.and Casagrande.me.hods we.e.compile. to asse.s the.re.ationships among spe.ifie. wate. conte.t,cone.pe.e.ration inde. e.T,and plasticity angle.e.T of fine.raine. *** re.ults indicate.that no unique.corre.ation e.ists among b,liquid limit of the.fall cone.te.t(LLc)and *** wate. conte.t at 1 mm cone.pe.e.ration e.0T corre.ate. we.l with b,plasticity ratio e.pT(*** ratio of plastic limit to liquid limit),and ***,the.pote.tial of using the.btan a diagram to classify soil plasticity was also discusse..

关键词： Atte.be.g limits Fall cone.te.t Plasticity angle Wate. conte.t Cone.pe.e.ration inde. Plasticity ratio

How be.ie.able.are.publishe. laboratory data?A de.pe. look into syste.-compliance.and e.astic modulus

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2021年第3期13卷 487-499页

作者： Aly Abde.aziz giovanni Grasse.li De.artme.t of Civil and Mine.al e.gine.ring University of Toronto35 St.George StreetTorontoOntarioM5S 1A4Canada

e.astic modulus(e.inte.pre.ation is de.atable.with limite. lite.ature.de.ailing the.impact of *** addre.s this impact,a compre.e.sive.te.ting sche.ule.using an aluminium 6061(Al)sample.is carrie. out on se.e.al syste.s unde. various te.t *** is chose. as it is e.trude. and adhe.e. to we.l de.ine. shape.tole.ance. and e.astic prope.tie..A robust me.hod,using the.Savitzky-Golay filte.,is introduce. to ide.tify significant slope.change. in the.stre.se.train *** the.load in the.te.t syste. is we.l de.ine.,the.re.orde. de.ormation is corre.te. to the.e.pe.te. value.of Al re.ulting in a syste.-compliance.*** re.ults across the.te.ting syste.s and te.t se.ups showe. significant variance.with the.re.orde. e.always lowe. than the.anticipate. *** numbe. of compone.ts within the.syste. ove. which the.de.ormation is me.sure. had the.most significant impact,lowe.ing the.e.pe.te. e.by up to 50%.Additionally,the.syste.-compliance.factor is inconsiste.t across diffe.e.t syste.s and ***,it is e.ide.tly prove. that e.ch se.up must be.se.arate.y e.aluate. for its syste.-compliance.and that no single.value.e.ists across syste.s and *** findings are.the. proje.te. onto a se.ie. of uniaxial compre.sive.stre.gth(UCS)te.ts carrie. out on Stanste.d granite.SS GR)*** corre.te. e.50 and e.vg value. for syste.-compliance.of the.sample. are.within1%for e.ch syste. as oppose. to be.ng50%*** findings conclude.that it is de.me. ne.e.sary and of utmost importance.that the.de.ormation be.corre.te. to accommodate.the.syste.compliance.to obtain re.iable.re.ults.

关键词： Syste.-compliance e.astic modulus Stre.se.train Compre.sive.stre.gth of rock

H pylori re.e.tor MHC classⅡcontribute. to the.dynamic gastric e.ithe.ial apoptotic re.ponse

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroe.te.ology 2006年第33期12卷 4689-4693页

作者： David A Bland giovanni Suare. e.le. J Be.wick Johanna C Sie.ra Victor e.Re.e. the.Unive.sity of Te.as Me.ical Branch at Galve.ton TX 77555-0366 United States

AIM： To inve.tigate.the.role.of MHC class Ⅱ in the.modulation of gastric e.ithe.ial ce.l apoptosis induce. by H pylori infe.tion. Me.HODS： Afte. stimulating a human gastric e.ithe.ial ce.l line.with bacte.ia or agonist antibodie. spe.ific for MHC class Ⅱ and CD95, the.quantitation of apoptotic and anti-apoptotic e.e.ts, including caspase.activation, BCL-2 activation, and FADD re.ruitme.t, was pe.forme. with a fluorome.ric assay, a cytome.ric be.d array, and confocal microscopy, re.pe.tive.y. Re.ULTS： Pre.re.tme.t of N87 ce.ls with the.anti-MHC class ⅡIgM antibody RFD1 re.ulte. in a re.uction in global caspase.activation at 24 h of H pylori infe.tion. Whe. caspase.3 activation was spe.ifically me.sure., crosslinking of MHC class Ⅱ re.ulte. in marke.ly re.uce. caspase.activation, while.simple.ligation of MHC class Ⅱ did not. Crosslinking of MHC class Ⅱ also re.ulte. in an incre.se. activation of the.anti-apoptosis mole.ule.BCL-2 compare. to simple.ligation. Confocal microscope.analysis de.onstrate. that the.pre.re.tme.t of gastric e.ithe.ial ce.ls with a crosslinking anti-MHC class Ⅱ IgM blocke. the.re.ruitme.t of FADD to the.ce.l surface. CONCLUSION： The.ability of MHC class Ⅱ to modulate.gastric e.ithe.ial apoptosis is at le.st partially de.e.de.t on its crosslinking. The.crosslinking of this mole.ule.has anti-apoptotic e.fe.ts during the.e.rlie. time.points of Hpylori infe.tion. This e.fe.t is possibly me.iate. by the.ability of MHC class Ⅱ to modulate.the.activation of the.pro-apoptotic re.e.tor Fas by blocking the.re.ruitme.t of the.acce.sory mole.ule.FADD, and this de.ay in apoptosis induction could allow for prolonge. cytokine.se.re.ion by Hpylori-infe.te. gastric e.ithe.ial ce.ls.

关键词： Hpylori e.ithe.ium Apoptosis Class Ⅱ MHC

Ge.fluids Hoste. in the.De.p Crust: From Syste.atics to Parame.rization of the.r Significance

在线全文

学校读者我要写书评

暂无评论

Acta Ge.logica Sinica(e.glish e.ition) 2021年第S1期95卷 31-33页

作者： giovanni MARTINe.LI INGV Istituto Nazionale.di Ge.fisica e.Vulcanologia Department of PalermoPalermoItaly Northwe.t Institute.of e.o-e.vironme.t and Re.ource. Chinese Academy of SciencesLanzhouChina Ke. Laboratory of Pe.role.m Re.ource. Gansu Province/Key Laboratory of Petroleum Resources ResearchInstitute of Geology and GeophysicsChinese Academy of SciencesLanzhouChina

e.rthquake.is a sudde. re.e.se.of e.e.gy due.to fault *** se.e.ity of the.damage. can be.minimize. by de.e.opme.t of a culture.of pre.e.tion which include. the.Se.smic Hazard Asse.sme.t,microzonation studie. and appro... 详细信息

关键词： probabilistic se.smic hazard asse.sme.t de.e.ministic se.smic hazard asse.sme.t he.ium isotope. ge.che.ical prospe.tion e.rthquake.pre.ursors