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Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model

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Asian Pacific Journal of Tropical Biomedicine 2023年第5期13卷 214-221页

作者： Xuan-Hai Do Trong Nghia nguyen Thanh Chung Dang Thi Thanh Mai nguyen Trung Nhan nguyen Van Nhat Truong Do Huu Tho Le Xuan Hai nguyen Hoang Phu Dang giang-linh nguyen Dinh-Khanh Hoang Van-Quan Le Van-Mao Can Department of Practical and Experimental Surgery Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Reconstructive and Microsurgery Craniofacial and Reconstructive Surgery CentreMilitary Central Hospital 108Hanoi 10000Vietnam Department of Anatomic Pathology Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Faculty of Chemistry University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh City 70000Vietnam Faculty of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi 10000Vietnam Department of Ultrasound Imaging Diagnostics CentreMilitary Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Functional Diagnostics Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Pathophysiology Vietnam Military Medical UniversityHanoi 10000Vietnam

Objective:To investigate the anti-inflammatory and analgesic effects of Solanum procumbens on complete Freund’s adjuvantinduced arthritis rat ***:We isolated and identified five compounds in the ethanolsoluble Solanum procumbens extract(SP)with anti-inflammatory effects,including ursolic acid,β-sitosterol,hexadecanoic acid,cisvaccenic acid,and vanillic ***,we investigated the anti-inflammatory effects of SP on rheumatoid arthritis symptoms,including paw volumes,local temperatures,withdrawal latency,and mechanical withdrawal threshold at the hind paw and white blood cell(WBC)number from complete Freund’s adjuvant-induced arthritis rat ***:We have successfully established a complete Freund’s adjuvant-induced arthritis rat model at a low dose(1 mg/mL).SP extract significantly reduced paw volumes(P<0.05),prolonged withdrawal latencies(P<0.05),decreased local temperature,and increased the mechanical withdrawal threshold(P<0.05),but only SP extract at the dose of 300 mg/kg significantly decreased WBC ***:SP extract could be a potential medication candidate with anti-inflammatory effects for arthritis,but it requires further investigation into the mechanism of the SP and its effectiveness on other models as well as clinical trials.

关键词： Solanum procumbens Arthritis Anti-inflammation Complete Freund's adjuvant Rats

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Cellular models of stress resistance may pave ways to fight neurodegenerative diseases

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Neural Regeneration Research 2025年第9期20卷 2579-2580页

作者： Thu nguyen Minh Pham Christian Behl Institute of Pathobiochemistry University Medical Center of the Johannes Gutenberg UniversityMainzGermany

Alzheimer's disease(AD),the most common form of neurodegeneration,is characterized by selective neuronal vulnerability and brain regionselective neuron *** entorhinal cortex and hippoc,ampal CA1 projection neurons are at greater risk in AD whereas other regions display resistance to ***,the cerebellum,a phylogenetically very old region,is affected only very late in the disease progression.

关键词： cortex resistance Alzheimer

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Shear strength model of the reinforced concrete beams with embedded through-section strengthening bars

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Frontiers of Structural and Civil Engineering 2022年第7期16卷 843-857页

作者： linh Van Hong BUI Phuoc Trong nguyen Faculty of Civil Engineering Ho Chi Minh City Open UniversityHo Chi Minh City 700000Vietnam

In this study,finite element(FE)analysis is utilized to investigate the shear capacity of reinforced concrete(RC)beams strengthened with embedded through-section(ETS)*** of critical variables on the beam shear strength,including the compressive strength of concrete,stiffness ratio between ETS bars and steel stirrups,and use of ETS strengthening system alone,are parametrically investigated.A promising method based on the bond mechanism between ETS strengthening and concrete is then proposed for predicting the shear resistance forces of the strengthened *** expression for the maximum bond stress of the ETS bars to concrete is *** new expression eliminates the difficulty in the search and selection of appropriate bond parameters from adhesion *** results obtained from the FE models and analytical models are validated by comparison with those measured from the ***,the model proposed in this study demonstrates better performance and more accuracy for prediction of the beam shear-carrying capacity than those of existing *** results obtained from this study can also serve researchers and engineers in selection of the proper shear strength models for design of ETS-strengthened RC beams.

关键词： embedded through-section strengthening fiber-reinforced polymer finite element shear strength model bond mechanism

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Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 467-500页

作者： Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models Duc-Dam nguyen nguyen Viet Tiep Quynh-Anh Thi Bui Hiep Van Le Indra Prakash Romulus Costache Manish Pandey Binh Thai Pham Faculty of Civil Engineering University of Transport TechnologyThanh XuanHa Noi100000Vietnam Faculty of Hydraulic Engineering Hanoi University of Civil EngineeringHa Noi100000Vietnam DDG(R)Geological Survey of India Gandhinagar382010India Research Institute of the University of Bucharest Bucharest050663Romania National Institute of Hydrology and Water Management Bucharest013686Romania Department of Civil Engineering Transilvania University of BrasovBrasov500152Romania Danube Delta National Institute for Research and Development Tulcea820112Romania Marwadi University Research Center(MURC) Marwadi UniversityRajkotGujaratBharat360003India Department of Civil Engineering Faculty of Engineering&TechnologyMarwadi UniversityRajkotGujaratBharat360003India

This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and ***,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and *** models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to *** factors were instrumental in predicting the output variable,which was the probability of landslide *** analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other *** AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of *** results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.

关键词： Landslide susceptibility map spatial analysis ensemble modelling information values(IV)

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Effects of pressure relief holes on coal burst:Insights from true-triaxial unloading tests

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3378-3394页

作者： Fuqiang Ren Murat Karakus giang nguyen Thomas Bruning School of Civil Engineering University of Science and Technology LiaoningAnshan114051China Mining and Petroleum Engineering The University of AdelaideAdelaideSouth Australia5005Australia State Key Laboratory for Geomechanics&Deep Underground Engineering China University of Mining and TechnologyBeijing100083China School of Architecture and Civil Engineering The University of AdelaideSouth Australia5005Australia

Drilling pressure relief is one of the methods to reduce the risk of coal bursts in deep ***,the effect of the drill hole orientations has not been studied well enough to understand their impact on the burst failure *** this study,we investigated two designs of drill hole *** first design includes drill holes located on the upper free face of the rectangular samples and labelled as upper hole(UH)and centre hole(CH)e the long axes of the drill holes are aligned with minor principal stress,s3,*** second design includes drill holes at the top(TH)and the side(SH)of the rectangular samples in which the long axes of the drill holes are aligned with the maximum,s1,and intermediate principal stress,s2,directions,*** coal samples with the proposed drill hole orientations were subjected to the true-triaxial unloading coal burst *** results show that the drill holes reduce the risk of coal ***,we found that the intensity of coal burst was significantly reduced with the SH-type,followed by the *** also observed that the coal burst intensity is reduced better for the CH,UH,TH,and SH-type drilling ***,it was found that the orientations of drill holes have little influence on the failure mode(splitting).The acoustic emission(AE)activities for coal with drill holes noticeably decreased,especially for the UH and CH *** drill holes reduced the upper limit of the AE entropy(chaos of microcracks generation).However,regarding reducing the coal burst risk,the TH and SH are less effective than UH and CH.

关键词： Coal burst Triaxial unloading Drilling orientation Ejection characteristic Acoustic emission(AE)

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Construction of a High‑Performance Composite Solid Electrolyte Through In‑Situ Polymerization within a Self‑Supported Porous Garnet Framework

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Nano-Micro Letters 2024年第5期16卷 56-70页

作者： An‑giang nguyen Min‑Ho Lee Jaekook Kim Chan‑Jin Park Department of Materials Science and Engineering Chonnam National University77 Yongbong‑roBuk‑guGwangju 61186South Korea

Composite solid electrolytes(CSEs)have emerged as promising candidates for safe and high-energy–density solid-state lithium metal batteries(SSLMBs).However,concurrently achieving exceptional ionic conductivity and interface compatibility between the electrolyte and electrode presents a significant challenge in the development of high-performance CSEs for *** overcome these challenges,we present a method involving the in-situ polymerization of a monomer within a self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZT)to produce the *** synergy of the continuous conductive LLZT network,well-organized polymer,and their interface can enhance the ionic conductivity of the CSE at room ***,the in-situ polymerization process can also con-struct the integration and compatibility of the solid electrolyte–solid electrode *** synthesized CSE exhibited a high ionic conductivity of 1.117 mS cm^(-1),a significant lithium transference number of 0.627,and exhibited electrochemical stability up to 5.06 V ***/Li+at 30℃.Moreover,the Li|CSE|LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) cell delivered a discharge capacity of 105.1 mAh g^(-1) after 400 cycles at 0.5 C and 30℃,corresponding to a capacity retention of 61%.This methodology could be extended to a variety of ceramic,polymer electrolytes,or battery systems,thereby offering a viable strategy to improve the electrochemical properties of CSEs for high-energy–density SSLMBs.

关键词： Scalable tape-casting method Self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12) Composite solid electrolyte LiF-and B-rich interphase layers

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A Complex Fuzzy LSTM Network for Temporal-Related Forecasting Problems

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Computers, Materials & Continua 2024年第9期80卷 4173-4196页

作者： nguyen Tho Thong nguyen Van Quyet Cu nguyen Giap nguyen Long giang Luong Thi Hong Lan Institute of Information Technology Vietnam Academy of Science and TechnologyHoang Quoc VietCau GiayHanoi100000Vietnam Academic Affairs Department Thai Nguyen University of EducationThai Nguyen250000Vietnam Center of Science and Technology Research and Development Thuongmai UniversityHo Tung MauCau GiayHanoi100000Vietnam Faculty of Information Technology Hanoi University of IndustryBac Tu LiemHanoi100000Vietnam

Time-stamped data is fast and constantly growing and it contains significant information thanks to the quick development ofmanagement platforms and systems based on the Internet and cutting-edge information communication *** the time series data including time series prediction has many practical *** new techniques were developed for use with various types of time series data in the prediction *** those,this work suggests a unique strategy to enhance predicting quality on time-series datasets that the timecycle matters by fusing deep learning methods with fuzzy *** order to increase forecasting accuracy on such type of time-series data,this study proposes integrating deep learning approaches with fuzzy ***,it combines the long short-termmemory network with the complex fuzzy set theory to create an innovative complex fuzzy long short-term memory model(CFLSTM).The proposed model adds a meaningful representation of the time cycle element thanks to a complex fuzzy set to advance the deep learning long short-term memory(LSTM)technique to have greater power for processing time series *** on standard common data sets and real-world data sets published in the UCI Machine Learning Repository demonstrated the proposedmodel’s utility compared to other well-known forecasting *** results of the comparisons supported the applicability of our proposed strategy for forecasting time series data.

关键词： Complex fuzzy set long short-term memory(LSTM) CFLSTM T-CFLSTM

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Discrete-time sliding mode control with power rate exponential reaching law of a pneumatic artificial muscle system

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Control Theory and Technology 2022年第4期20卷 514-524页

作者： Quy-Thinh Dao Trung-Kien Le Tri Van-Anh nguyen Manh-linh nguyen School of Electrical and Electronic Engineering Hanoi University of Science and TechnologyDai Co VietHanoi 11615Vietnam

This paper develops a discrete-time sliding mode controller with a power rate exponential reaching law approach to enhance the performance of a pneumatic artificial muscle system in both reaching time and chattering *** proposed method dynamically adapts to the variation of the switching function,which is based on an exponential term and a power rate term of the sliding ***,the controlled system can achieve high tracking performance while still obtain chattering-free ***,the effectiveness of the proposed method is validated through multiple experimental tests,focused on a dual pneumatic artificial muscle ***,experimental results show the effectiveness of the proposed approach in this paper.

关键词： Pneumatic artificial muscle Discrete-time sliding mode control Exponential reaching law Chattering

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Effect of loading rate and time delay on the tangent modulus method(TMM)in coal and coal measured rocks

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International Journal of Coal Science & Technology 2022年第6期9卷 51-63页

作者： Zulfiqar Ali Murat Karakus giang D.nguyen Khalid Amrouch School of Civil Environmental and Mining EngineeringUniversity of AdelaideAdelaideSA 5000Australia Australian School of Petroleum and Energy University of AdelaideAdelaideSA 5000Australia Geology&Sustainable Mining Mohammed VI Polytechnic University43150 BenguerirMorocco

Non-destructive techniques of in-situ stress measurement from oriented cored rocks have great potential to be developed as a cost cost-effective and reliable alternative to the conventional overcoring and hydraulic fracturing *** tangent modulus method(TMM)is one such technique that can be applied to oriented cored rocks to measure in-situ *** the deformation rate analysis(DRA),the rock specimen is subjected to two cycles of uniaxial compression and the stress-tangent modulus curve for the two cycles is obtained from the stress-strain curve.A bending point in the tangent modulus curve of the first cycle is observed,separating it from the tangent modulus curve of the second *** point of separation between the two curves is assumed to be the previously applied maximum stress.A number of experiments were conducted on coal and coal measured rocks(sandstone and limestone)to understand the effect of loading conditions and the time *** specimens were preloaded,and cyclic compressions were applied under three different modes of loading,four different strain rates,and time delays of up to one *** bending point in the stress-tangent modulus curves occurred approximately at the applied pre-stress levels under all three loading modes,and no effect of loading rate was observed on the bending points in ***,a clear effect of time delay was observed on the TMM,contradicting the DRA *** could be due to the sensitivity of TMM and the range of its applicability,all of which need further investigation for the in-situ stress measurement.

关键词： Tangent modulus method TMM Deformation rate analysis DRA Time delay Strain rate

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Double-loop Control Structure Using Proportional Resonant and Sequence-decoupled Resonant Controllers in Static Coordinates for Dynamic Voltage Restorer

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Chinese Journal of Electrical Engineering 2019年第3期5卷 10-19页

作者： Vu Thai Hung Hongchun Shu Le Ngoc giang nguyen Duc The School of Electric Power Engineering Kunming University of Science and TechnologyKunming 650500China AD-AF Academy of Viet Nam Son TayHa Noi 100000Viet Nam

Among incidents on grids,the sag/swell voltage is considered as the most frequent *** solve this problem,custom power devices are *** particular,the dynamic voltage restorer(DVR)is a modern and efficient customer *** are used to mitigate voltage sag/swells and harmonics on the load bus,thus protecting the sensitive *** DVR is a serial compensator that applies a voltage to the point of common coupling to maintain the voltage of sensitive load at the nominal *** improve the performance of DVRs,in this study,the control strategy of the two-stage loop circuit is *** external voltage control loop uses a sequence-decoupled resonant(SDR)controller,and the inner current-control loop uses the proportional resonant(PR)controller implemented in the stationary frameαβ.

关键词： Dynamic voltage restorer PR controller SDR controller nonlinear load

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