Cellular models of stress resistance may pave ways to fight neurodegenerative diseases

作     者：Thu Nguyen Minh Pham Christian Behl 

作者机构：Institute of PathobiochemistryUniversity Medical Center of the Johannes Gutenberg UniversityMainzGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2025年第20卷第9期

页      面：2579-2580页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：supported by a grant of the Deutsche Forschungsgemeinschaft(DFG CRC1177 and joint DFG/ANR grant)(to CB) a fellowship of the Deutscher Akademischer Austauschdienst(DAAD)(to TNMP) 

主　　题：cortex resistance Alzheimer 

摘      要：Alzheimer s disease(AD),the most common form of neurodegeneration,is characterized by selective neuronal vulnerability and brain regionselective neuron *** entorhinal cortex and hippoc,ampal CA1 projection neurons are at greater risk in AD whereas other regions display resistance to ***,the cerebellum,a phylogenetically very old region,is affected only very late in the disease progression.