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Contrast Normalization Strategies in Brain Tumor Imaging:From Preprocessing to Classification

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1539-1562页

作者： Samar M.Alqhtani Toufique A.Soomro Faisal bin Ubaid ahmed Ali Muhammad Irfan Abdullah A.Asiri Department of Information Systems College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Electronic Engineering The University of LarkanoLarkanaSindh75660Pakistan Computer Science Department Sukkur IBA UniversitySukkurSindh65200Pakistan Eletrical Engineering Department Sukkur IBA UniversitySukkurSindh65200Pakistan Electrical Engineering Department College of EngineeringNajran UniversityNajran61441Saudi Arabia Radiological Sciences Department College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia

Cancer-related to the nervous system and brain tumors is a leading cause of mortality in various *** resonance imaging(MRI)and computed tomography(CT)are utilized to capture brain *** plays a crucial role in the diagnosis of brain tumors and the examination of other brain ***,manual assessment of MRI images by radiologists or experts is performed to identify brain tumors and abnormalities in the early stages for timely ***,early diagnosis of brain tumors is intricate,necessitating the use of computerized *** research introduces an innovative approach for the automated segmentation of brain tumors and a framework for classifying different regions of brain *** proposed methods consist of a pipeline with several stages:preprocessing of brain images with noise removal based on Wiener Filtering,enhancing the brain using Principal Component Analysis(PCA)to obtain well-enhanced images,and then segmenting the region of interest using the Fuzzy C-Means(FCM)clustering technique in the third *** final step involves classification using the Support Vector Machine(SVM)*** classifier is applied to various types of brain tumors,such as meningioma and pituitary tumors,utilizing the Contrast-Enhanced Magnetic Resonance Imaging(CE-MRI)*** proposed method demonstrates significantly improved contrast and validates the effectiveness of the classification framework,achieving an average sensitivity of 0.974,specificity of 0.976,accuracy of 0.979,and a Dice Score(DSC)of ***,this method exhibits a shorter processing time of 0.44 s compared to existing *** performance of this method emphasizes its significance when compared to state-of-the-art methods in terms of sensitivity,specificity,accuracy,and *** enhance the method further in the future,it is feasible to standardize the approach by incorporating a set of classifiers to increase the robustness of the brain classi

关键词： Brain tumor magnetic resonance imaging principal component analysis fuzzy c-clustering support vector machine

Preparation and Characterization of Vitamin-D Incorporated Marshmallow

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Open Journal of Medicinal Chemistry 2024年第2期14卷 15-28页

作者： Muhammad Ajmal Rubina Bibi Rauf Imran Muhammad ahmed bin Azher College of Pharmacy University of Punjab Lahore Pakistan Department of Chemistry Government College Women University Sialkot Pakistan

This project looks at a novel way to enhance the sensory experience of vitamin D ingestion by incorporating it into marshmallows. This investigation used a human panel taste test with twelve individuals, an index of swelling, and a stability evaluation. Samples of vitamin D infused marshmallows were prepared and given to participants in the human panel taste test, which evaluated mouthfeel and flavor. By analyzing dissolving behavior, the swelling index test revealed unexpected erosion. In addition, a temperature threshold for storage conditions was found through a temperature sensitivity test. All of these techniques assessed the feasibility and palatability of vitamin D supplementation with marshmallow flavor, offering insights into both the possible advantages and difficulties. The marshmallow infusion technique effectively covered up the disagreeable taste of vitamin D pills, leading to reviews that were overwhelmingly favorable (“Moderate Sweet”) and that indicated a pleasant mouthfeel. During the swelling index test, it showed erosion behavior, suggesting a certain kind of dissolution that is advantageous for nutritional absorption. Furthermore, the study discovered a temperature sensitivity threshold, highlighting how crucial proper storage conditions are.

关键词： Vitamin D Marshmellow Infusion Taste Making Supplement Adherence Nutrient Delivery

Improved Manta Ray Foraging Optimizer-based SVM for Feature Selection Problems:A Medical Case Study

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Journal of Bionic Engineering 2024年第1期21卷 409-425页

作者： Adel Got Djaafar Zouache Abdelouahab Moussaoui Laith Abualigah ahmed Alsayat Faculty of informatics University of Science and Technology Houari BoumedieneAlgiersAlgeria LRIA Laboratory University of Science and Technology Houari BoumedieneAlgiersAlgeria Computer Science Department University of Mohamed El Bachir El IbrahimiBordj Bou ArreridjAlgeria Computer Science Department University of Ferhat AbbasSetifAlgeria Computer Science Department Prince Hussein Bin Abdullah Faculty for Information TechnologyAl al-Bayt UniversityMafraq 25113Jordan Department of Computer Science College of Computer and Information SciencesJouf UniversityJoufSaudi Arabia Department of Electrical and Computer Engineering Lebanese American University13-5053ByblosLebanon Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman 19328Jordan MEU Research Unit Middle East UniversityAmman 11831Jordan Applied science research center Applied science private universityAmman 11931Jordan School of Computer Sciences Universiti Sains Malaysia11800 PenangMalaysia School of Engineering and Technology Sunway University Malaysia27500 Petaling JayaMalaysia

Support Vector Machine(SVM)has become one of the traditional machine learning algorithms the most used in prediction and classification ***,its behavior strongly depends on some parameters,making tuning these parameters a sensitive step to maintain a good *** the other hand,and as any other classifier,the performance of SVM is also affected by the input set of features used to build the learning model,which makes the selection of relevant features an important task not only to preserve a good classification accuracy but also to reduce the dimensionality of *** this paper,the MRFO+SVM algorithm is introduced by investigating the recent manta ray foraging optimizer to fine-tune the SVM parameters and identify the optimal feature subset *** proposed approach is validated and compared with four SVM-based algorithms over eight benchmarking ***,it is applied to a disease Covid-19 *** experimental results show the high ability of the proposed algorithm to find the appropriate SVM’s parameters,and its acceptable performance to deal with feature selection problem.

关键词： Support vector machine Parameters tuning Feature selection Bioinspired algorithms Manta ray foraging optimizer

Interplay of serum biomarkers bilirubin andγ-glutamyltranspeptidase in predicting cardiovascular complications in type-2 diabetes mellitus

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World Journal of Diabetes 2024年第6期15卷 1074-1078页

作者： Ebtesam Abdullah Al-Suhaimi Abdullah ahmed Al-Rubaish Scientific Research and Innovation Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia King Abdulaziz and his Companions Foundation for Giftedness and Creativity“Mawhiba” Riyadh 11372Saudi Arabia College of Medicine Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia

This editorial synthesizes insights from a series of studies examining the interplay between metabolic and oxidative stress biomarkers in cardiovascular disease(CVD),focusing particularly on type-2 diabetes mellitus(T2DM)and acute coronary syndrome(ACS).The central piece of this synthesis is a study that investigates the balance between oxidative stress and antioxidant systems in the body through the analysis of serum bilirubin andγ-glutamyltranspeptidase(γ-GGT)levels in T2DM patients with *** study highlights serum bilirubin as a protective antioxidant factor,while elevatedγ-GGT levels indicate increased oxidative stress and correlate with major adverse cardiovascular *** to this,other research contributions revealγ-GGT’s role as a risk factor in ACS,its association with cardiovascular mortality in broader populations,and its link to metabolic syndrome,further elucidating the metabolic dysregulation in *** collective findings from these studies underscore the critical roles ofγ-GGT and serum bilirubin in cardiovascular health,especially in the context of T2DM and *** providing a balanced view of the body’s oxidative and antioxidative mechanisms,these insights suggest potential pathways for targeted interventions and improved prognostic assessments in patients with T2DM and *** synthesis not only corroborates the pivotal role ofγ-GGT in cardiovascular pathology but also introduces the protective potential of antioxidants like bilirubin,illuminating the complex interplay between T2DM and heart *** studies collectively underscore the critical roles of serum bilirubin andγ-GGT as biomarkers in cardiovascular health,particularly in T2DM and ACS contexts,offering insights into the body’s oxidative and antioxidative *** synthesis of research supports the potential of these biomarkers in guiding therapeutic strategies and improving prognostic assessments for patients with T2DM and some CVD.

关键词： Type-2 diabetes mellitus Acute coronary syndrome Serum biomarkers γ-glutamyltranspeptidase Bilirubin Cardiovascular disease

Surface morphology and cell viability of samarium(Ⅲ) oxide/chromium(Ⅲ) oxide/graphene oxide/polycaprolactone targeting wound dressing

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Journal of Rare Earths 2024年第3期42卷 555-561,I0005页

作者： Muteb H.Alshammari ahmed Onayzan Alshammari Mohamed Tharwat Elabbasy Rafat Zreiq Faris Mohammed Albati M.A.El-Morsy A.A.Menazea Department of Health Informatics College of Public Health and Health InformaticsUniversity of Ha'ilHa'ilSaudi Arabia Department of Surgery College of MedicineUniversity of Ha'ilHa'ilSaudi Arabia Department of Public Health College of Public Health and HealthInformaticsHalUniversityHa'il2440Saudi Arabi Food Control Department Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt Applied Science Research Center Applied Science Private UniversityAmman541350Jordan College of Shariah and Law Ha'il UniversityHa'il2440Saudi Arabia College of Science and Humanities in Al-Kharj Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Department Faculty of ScienceUniversity of DamittaNew Damietta34517.Egyp Spectroscopy Department Physics Research InstituteNational Research CentreDokki12622GizaEgypt

Combinations of metal and lanthanide oxides have been done through casted films for potential medical applications. In this regard, samarium(Ⅲ) oxide/chromium(Ⅲ) oxide/graphene oxide(GO)/polycaprolactone(PCL) based films nano-composites(NCs) were fabricated, pointing their utilization as a biological scaffold for wound dressing purposes. Also, samarium(Ⅲ) oxide and chromium(Ⅲ) oxide have been merged as promising optical constituents due to their unique optical behavior. The structural and compositional examination of the studied NCs was executed by X-ray diffraction(XRD), Raman, and field emission scanning electron microscopy(FESEM). The Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCL NC exhibits a surface with a lower roughness degree owing to the presence of GO. Cr_(2)O_(3)shows size reduction upon GO insertion to reach 1.2 μm as the average grain size, whilst Sm_(2)O_(3)records an average grain size of less than 1 μm. As well, the polymeric nano-compositions exhibit variation in contact angle values that hit 29.76°± 3.52°for Sm_(2)O_(3)/PCL, and 48.62°± 1.37°for Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCL as the second lowest contact angle. The optical behavior contributes to absorption edge relocation along the x-axis from 1.7 eV for pure PCL, to 2.65 eV for Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCL. Regarding biological responses, the cell exposed to 2.5 μg/m L of Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCL shows cell viability of 119.31%, while 5 μg/m L hits 99.6%. Additionally, the resulting cell attachment micrographs show layers of fibroblast tissue, besides the proliferation and growth of cultivated cells. Thus, the Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCL scaffold provides 3D proliferation of fibroblast cells endorsing the wound healing process.

关键词： Wound healing Wound dressing Polycaprolactone Sm_(2)O_(3) Cr_(2)O_(3) Rare earths

Impact of Action Observation Therapy along with Usual Physiotherapy Intervention of Individual with Alzheimer’s Disease

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Advances in Alzheimer's Disease 2024年第1期13卷 1-10页

作者： Zahid bin Sultan Nahid Faruq ahmed Tuhin Ahammed Md Kutub Uddin Md Sirazul Islam S M Maruf Hossain Sajib Md Rafiqul Islam Department of Physiotherapy Saic College of Medical Science and Technology Mirpur Bangladesh Department of Physiotherapy Centre for the Rehabilitation of the Paralysed (CRP) Savar Bangladesh Department of Physiotherapy Centre for the Rehabilitation of the Paralysed (CRP) Mymensingh Bangladesh Department of Physiotherapy Centre for the Rehabilitation of the Paralysed (CRP) Mirpur Bangladesh Department of Physiotherapy State College of Health Sciences Dhaka Bangladesh

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairments in the initial stage, which lead to severe cognitive dysfunction in the later stage. Action observation therapy (AOT) is a multisensory cognitive rehabilitation technique where the patient initially observes the actions and then tries to perform. The study aimed to examine the impact of AOT along with usual physiotherapy interventions to reduce depression, improve cognition and balance of a patient with AD. A 67 years old patient with AD was selected for this study because the patient has been suffering from depression, dementia, and physical dysfunction along with some other health conditions like diabetes and hypertension. Before starting intervention, a baseline assessment was done through the Beck Depression Inventory (BDI) tool, the Mini-Cog Scale, and the Berg Balance Scale (BBS). The patient received 12 sessions of AOT along with usual physiotherapy interventions thrice a week for four weeks, which included 45 minutes of each session. After four weeks of intervention, the patient demonstrated significant improvement in depression, cognition, and balance, whereas the BDI score declined from moderate 21/63 to mild 15/63 level of depression. The Mini-Cog score improved from 2/5 to 4/5, and the BBS score increased from 18/56 to 37/56. It is concluded that AOT along with usual physiotherapy intervention helps to reduce depression, improve cognition and balance of people with AD.

关键词： Alzheimer’s Disease Action Observation Therapy Physiotherapy Intervention

Burden of routine orthopedic implant removal a single center retrospective study

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World Journal of Orthopedics 2024年第2期15卷 139-146页

作者： Ammar K AlOmran Nader Alosaimi ahmed A Alshaikhi Omar M Bakhurji Khalid J Alzahrani Basil Ziyad Salloot Tamim Omar Alabduladhem ahmed I AlMulhim Arwa Alumran Department of Orthopedic College of MedicineImam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia Health Information Management and Technology Department Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia

BACKGROUND Open reduction and internal fixation represent prevalent orthopedic procedures,sparking ongoing discourse over whether to retain or remove asymptomatic *** consensus on this matter is paramount for orthopedic *** study aims to quantify the impact of routine implant removal on patients and healthcare facilities.A retrospective analysis of implant removal cases from 2016 to 2022 at King Fahad Hospital of the University(KFHU)was conducted and subjected to statistical *** these cases,44%necessitated hospitalization exceeding one day,while 56%required only a single *** exhibited a 55%need for extended hospital stays,contrasting with 22.8%among the pediatric *** complication rate was 6%,with all patients experiencing at least one ***,34.1%required sick leave and 4.8%exceeded 14 *** anesthesia was predominant(88%).Routine implant removal introduces unwarranted complications,particularly in adults,potentially prolonging *** procedure strains hospital resources,tying up the operating room that could otherwise accommodate critical *** defined institutional guidelines are imperative to regulate this *** To measure the burden of routine implant removal on the patients and *** This is a retrospective analysis study of 167 routine implant removal cases treated at KFHU,a tertiary hospital in Saudi *** were collected in the orthopedic department at KFHU from February 2016 to August 2022,which includes routine asymptomatic implant removal cases across all age *** indications such as infection,pain,implant failure,malunion,nonunion,restricted range of motion,and prominent hardware were *** who had external fixators removed or joints replaced were also *** Between February 2016 and August 2022,360 implants were retrieved;however,only 167 of those who met the inclusion criteria were included in this

关键词： Implant removal Healed fracture Orthopedic implant Complications Healthcare system

Spinal dural arteriovenous fistula:a comprehensive review of the history,classification systems,management,and prognosis

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Chinese Neurosurgical Journal 2024年第1期10卷 48-56页

作者： Ali Alkhaibary Ahoud Alharbi Nada Alnefaie Hajar Alammar Alshaymaa M.Arishy Noor Alghanim Yazeed M.Aldhfyan Arwa Albaiahy Yahya H.Khormi Wael Alshaya Saad AlQahatani ahmed Aloraidi ahmed Alkhani Sami Khairy College of Medicine King Saud Bin Abdulaziz University for Health SciencesRiyadhSaudi Arabia King Abdullah International Medical Research Center RiyadhSaudi Arabia Division of Neurosurgery Department of SurgeryKing Abdulaziz Medical CityMinistry of National Guard-Health AffairsRiyadhSaudi Arabia Department of Neurosurgery National Neurosciences InstituteKing Fahad Medical CityRiyadhSaudi Arabia College of Medicine Jazan UniversityJazanSaudi Arabia Department of Neurosurgery King Faisal Specialist Hospital and Research CenterRiyadhSaudi Arabia Department of Surgery Faculty of MedicineJazan UniversityJazanSaudi Arabia

Spinal dural arteriovenous fistulas account for the majority of spinal vascular *** are typically located in the thoracolumbar region and are diagnosed in the middle-aged and elderly *** spinal dural arteriovenous fistulas have been postulated to be acquired,their exact development remains ***,the arteriovenous shunt is situated close to the spinal nerve root,inside the dura mater,where the blood from the radiculomeningeal artery and radicular vein *** history,there have been multiple classification systems of spinal arteriovenous shunts since *** were mainly based on the evolution of diagnostic studies as well as the treatment of these *** classification systems have undergone significant changes over the *** intracranial dural arteriovenous fistula,spinal dural arteriovenous fistula is progressive in *** neurological manifestations,due to venous congestion,tend to be insidious as well as *** include sensory deficits,such as paresthesia,bilateral and/or unilateral radicular pain affecting the lower limbs,and gait *** dural arteriovenous fistulas can be suspected on magnetic resonance imaging/magnetic resonance angiography and confirmed by digital subtraction angiography(DSA).The management includes surgery,endovascular therapy,and in selected cases,*** treatment goal of spinal dural arteriovenous fistula is to halt the progression of the *** prognosis depends on both the duration of symptoms as well as the clinical condition prior to *** present article comprehensively reviews the pathophysiology,changes in classification systems,natural history,clinical manifestations,radiological features,management,and prognosis.

关键词： Connection Endovascular Myelopathy Vascular

Comparative Analysis of Polyphenolic and Antioxidant Constituents in Dried Seedlings and Seedless Acacia nilotica Fruits

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Journal of Analysis and Testing 2018年第4期2卷 352-355页

作者： Amani AbdErahman Olalere Olusegun Abayomi AbdElhafiz Eltahir ahmed Abdurahman Hamid Nour Rosli bin Mohd Yunus ghada Mohamed Ibrahim Nassereldeen ahmed Kabbashi Faculty of Science and Technology Omdurman Islamic UniversityOmdurmanSudan Faculty of Chemical and Natural Resources Engineering Universiti Malaysia PahangGambangMalaysia Faculty of Animal Production Bahri UniversityBahriSudan International Islamic University Malaysia MalaysiaKOEBTE EngineeringKuala LumpurMalaysia

The phenolic and antioxidant constituents in Acacia nilotica fruits have become an important source of medicinal and thera-peutic benefit with powerful biological *** study investigated the phenolic content and antioxidant capacity of powdered Acacia fruits with seeds and without *** phenolic content and antioxidant capacities in them were deter-mined using Folin-Ciocalteu and DPPH free radical-scavenging *** total phenolic and antioxidants of *** with seeds were spectrophotometrically determined to be 47.61 and 6.18%greater than when the seeds were removed from the dried fruits,*** LC-MS/QTOF analysis shows the presence of 282 and 214 phenolic compounds in the methanol extracts of *** with seeds and without seeds,*** present study,therefore,revealed that dried *** fruits with seeds have higher total phenolic content,antioxidant capacity,and bioactive constituents,which indi-cated that they have more medicinal value than fruits without seeds.

关键词： Acacia nilotica Liquid chromatography-mass spectrometry Total phenolic content DPPH antioxidant capacity