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Phase-field numerical simulation of three-dimensional competitive growth of dendrites in a binary alloy

China Foundry 2018年第1期15卷 44-50页

作者： Li Feng Ya-long Gao Chang-sheng Zhu guo-sheng An Xin Deng Bei-bei Jia School of Materials and Engineering Lanzhou University of Technology State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of Technology School of Computer and Communication Lanzhou University of Technology

The normal vector of migration direction in the solid-liquid interface of dendrites was used to describe the phase-field governing equation. By using the three angles formed by the normal vector for the migration direction of the dendritic growth interface and the coordinate axes of the simulation region, the authors expressed the interfacial anisotropy equation, and built a phase-field model for the competitive growth of multiple grains. Taking a Al-2%mole-Cu binary alloy as an example, the competitive growth of multiple grains during isothermal solidification was simulated by applying parallel computing techniques. In addition, the phase field simulation results were verified by the experimental method. The simulation results show that the competitive growth of equiaxed dendrite is divided into two types: the first occurs during the process of competitive growth, the tips of primary dendrite on different grains taking part in the competition stop growing in their optimal growth direction; the second also occurs during competitive growth, the tips of primary dendrite which participate in the competition on different grains never stop growing in their optimal growth direction. The dendritic morphologies of the first competition growth type are divided into two types. Primary dendrites of grains taking part in the competition stop growing in their optimal growth direction and the competition plane enlarges when neither one wins the competition. However, when one wins the competition, the primary dendrites of grains with superiority go through the blocking grains and continue to grow in their optimal growth direction. The primary dendrites of inferior grains stop growing in their optimal growth direction and then instead grow in those areas without obstacles. The dendritic morphology of the second competition-growth type is shown to be the deformation of primary dendrites, which are mainly represented as the deflection and bending observed from different views. Compar

关键词： dendrite Al-Cu binary alloy competitive growth dendritic morphology

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Design of A Bionic Spudcan and Analysis of Penetration and Extraction Performances for Jack-up Platform

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China Ocean Engineering 2020年第1期34卷 80-88页

作者： guo sheng ZHUANG Hong TANG Wen-xian WU Wen-le LIU Qin WANG Yue-yang School of Mechanical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Jiangsu Provincial Key Laboratory of Advanced Manufacturing for Marine Mechanical Equipment Jiangsu University of Science and TechnologyZhenjiang 212003China

The mechanisms of soil structure interaction have drawn much attention in the past years in the installation and operation of jack-up platform. A bionic spudcan produced by biomimetic of egg and snail shell is proposed, and the performance of the penetration and extraction are analyzed by numerical method. The geometric contour of egg and snail shell is measured, and its mathematical model is established respectively. According to the structure of existing spudcan of jack-up platform, three kinds of typical biomimetic spudcan are designed. Furthermore, numerical analysis models of biomimetic spudcan are established respectively to study the soil structure interaction mechanism in the process of penetration and extraction, and contrastive analysis of resistance characteristics are carried out. To conclude, the results show that the biomimetic spudcan facilitates the platform installation, and it is also beneficial to the improvement of the bearing capacity of spudcan.

关键词： jack-up platform egg shell snail shell bionic design spudcan soil structure interaction

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Approach to N-Alkoxy-2-oxoindole for Mimicing SERMs Structure

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Chinese Chemical Letters 2005年第12期16卷 1593-1596页

作者： Ji Cheng CHU Dong Zhi LIU Hong sheng guo Kang ZHAO School of Chemical Engineering and Technology Tianjin University Tianjin 300072 Medical College Chinese People＇s Armed Police Force Tianjin 300071 College of Pharmaceutical and Biotechnology Tianjin UniversityTianjin 300072

Treatment of N-alkoxyamides with bis（trifluoroacetoxy）iodobenzene generated electron deficient nitrogen species, which readily cyclized onto aromatic ring to give N-alkoxy-2- oxoindoles. The effect of different subs... 详细信息

关键词： N-Alkoxyamides bis(trifluoroacetoxy)iodobenzene intramolecular cyclization

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Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5

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International Journal of Ophthalmology(English edition) 2021年第12期14卷 1834-1842页

作者： Xin Hua Peng Wu guo-sheng Gao Xiao-Lei Ye Department of Clinical Laboratory Hwa Mei HospitalUniversity of Chinese Academy of SciencesNingbo 315010Zhejiang ProvinceChina Ningbo Institute of Life and Health Industry University of Chinese Academy of SciencesNingbo 315010Zhejiang ProvinceChina Department of Clinical Laboratory Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina College of Life Sciences China West Normal UniversityNanchong 637009Sichuan ProvinceChina

AIM:To investigate the inhibitory effect of the combined use of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)and oridonin on choroidal melanoma cell lines,and to explore its underlying ***:MUM-2B and C918 cells were treated with different concentrations of TRAIL and oridonin,and MTT assay used to evaluate the inhibition rate of the two compounds on ***,the cell cycle distribution and apoptosis were detected by flow cytometry,and changes in apoptosis-related proteins such as death receptor 5(DR5),a-caspase-3,and x-linked inhibitor of apoptosis protein(XIAP)were detected by Western ***-2B cells were transfected with si-DR5,which interfered with the expression of the DR5 *** and Western blot assay were used to detect cell activity and apoptosis-related ***:When TRAIL and oridonin were simultaneously administered to the MUM-2B cells,the apoptosis rate was significantly higher than that by the two drugs ***,the effect of combined use of TRAIL and oridonin on C918 cells was not significantly different from that used *** cycle analysis showed that TRAIL and oridonin could induce G2/M arrest in MUM-2B *** Western blot results showed that the protein expression levels of the DR5,a-caspase-3,and BAX increased,while the expression levels of the anti-apoptosis-related proteins XIAP and BCL-2 were suppressed when TRAIL and oridonin simultaneously administered to MUM-2B *** the expression of DR5 gene in MUM-2B cells could reverse the inhibitory effect of oridonin and TRAIL on the proliferation and apoptosis induction of MUM-2B ***:The inhibitory effects of oridonin and TRAIL on MUM-2B cells are significantly enhanced when they were administered as a combined treatment,which may ascribe to up-regulation of DR5.

关键词： tumor necrosis factor-related apoptosisinducing ligand oridonin apoptosis choroidal melanoma

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A nonperturbative quantum electrodynamic approach to the theory of laser induced high harmonic generation

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Frontiers of physics 2015年第4期10卷 45-50页

作者： Chao Yu Jingtao Zhang Zhi-Wei Sun Zhenrong Sun Dong-sheng guo State Key Laboratory of Precision Spectroscopy Department of Physics East China Normal University Shanghai 200062 China State Key Laboratory of High-field Laser Physics Shanghai Institute of Optical and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China Key Laboratory of Microgravity Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China School of Physics Peking University Beijing 100871 China

Using nonperturbative quantum electrodynamics, we develop a scattering theory for high harmonic generation （HHG）. A transition rate formula for HHG is obtained. Applying this formula, we cal- culate the spectra of high harmonics generated from different noble gases shined by strong laser light. We study the cutoff property of the spectra. The data show that the cutoff orders of high harmonics are greater than that predicted by the ＂3.17＂ cutoff law. As a numerical experiment, the data obtained from our repeated calculations support the newly derived theoretical expression of the cutoff law. The cutoff energy of high harmonics described by the new cutoff law, in terms of the ponderomotive energy Up and the ionization potential energy Ip, is 3.34Up 1.83Ip. The higher cutoff orders predicted by this theory are due to the absorption of the extra photons, which participate only the photon-mode up-conversion and do nothing in the photoionization process.

关键词： high harmonic generation (HHG) cutoff law strong laser physics nonperturbative quantum electrodynamics transition rate formula

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Effects of Nitrogen Management on the Yield of Winter Wheat in Cold Area of Northeastern China

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Journal of Integrative Agriculture 2012年第6期11卷 1020-1025页

作者： LI Lian-peng LIU Yuan-ying LUO sheng-guo PENG Xian-long Resource and Environment College Northeast Agricultural UniversityHarbin 150030P.R.China

A plot experiment including four treatments, CK （N 105 kg ha-1 as urea, including a basal N application of 35 kg ha-I and a topdressing N 70 kg ha-1 at turned green stage） and optimized N management （OPT1, OPT2 and OPT3, applied two-thirds, one-third and two-fifths N at jointing stage, respectively, total N 60 kg ha-l）, was conducted to evaluate the effects of nitrogen management on growth and N uptake of winter wheat （Triticum aestivum）, Dongnong 1, which is the first highly cold tolerant winter wheat in China. Index of population quality, N uptake and yield were determined. The ear-bearing tiller rate was increased by above 12%, and the leaf area index, biomass and N uptake were significantly decreased （P〈O.05） at jointing stage. OPT treatments increased the grain to leaf area ratio at heading stage, the dry matter weight and N uptake after heading by 14.3-27.9%, 11.6-28.7% and 118.1-161.8 %, respectively. The yield of the OPT treatments was increased by 14.2-37.5% compared with CK, and there was a significant difference （P〈0.05） between CK and OPT1 treatments. Harvest index and N partial factor productivity （PFP, kg grain yield per kg N applied） was clearly enhanced from 0.4 and 35.6 kg, respectively for CK to an average of 0.48 （P〈0.05） and 77.6 kg （P〈0.05） in the OPT treatments. These results indicated that the optimized N management increased the harvest index, yield and N use efficiency by decreasing the N application rate and postponing N application time, improved wheat population quality, controlled excessive growth in the vegetative stages and increased dry matter and N accumulation rates after heading.

关键词： cold area winter wheat (Triticum aestivum) N management population quality yield

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Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection

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World Journal of Gastrointestinal Oncology 2023年第9期15卷 1636-1643页

作者： Jian-Jun Yin Xiao Hu Sen Hu guo-Hong sheng Department of Radiology Huangshi Maternity and Children's health HospitalAffiliated Maternity and Children's Health Hospital of Hubei Polytechnic UniversityHuangshi 435000Hubei ProvinceChina Department of Geriatrics Huangshi Central HospitalAffiliated Hospital of Hubei Polytechnic UniversityHuangshi 435000Hubei ProvinceChina

BACKGROUND Recurrence is the major challenge facing endoscopic submucosal dissection(ESD)-based treatment therapies for early gastric cancer(EGC).Urgent development of simple and easy surveillance approaches will enhance clinical treatment of the *** To explore the role of computed tomography(CT)recurrence in evaluating EGC after ESD *** We retrospectively recruited patients from our endoscopy department,between January 2002 and December 2015,and analyzed their basic characteristics,including symptoms,CT results,and results of endoscopy with biopsy,among *** Among a total of 2150 patients EGC patients surveyed,1362 met our inclusion and exclusion criteria and were therefore enrolled in our *** cohort’s sensitivity of CT for recurrent GC and specificity were 44.22%and 43.86%,respectively,with negative and positive predictive values of 40.15%(275/685)and 48.01%(325/677),*** area under the curve of arterial and venous CT values for recurrent EGC were 0.545,and 0.604,*** operating characteristic curve revealed no statistically significant differences between arterial and venous CT values for recurrent *** Enhanced CT has superior diagnostic efficacy,but less accuracy,compared to gold standard techniques in patients with recurrent EGC.

关键词： Computed tomography Early gastric cancer Gastric cancer Multi-slice spiral computed tomography

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The synthesis of micro-sized silicon carbide whiskers and the application for heat transfer enhancement

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Science China(Technological Sciences) 2014年第12期57卷 2371-2378页

作者： ZHANG Pei Gen LIANG Jian Dong YIN Li Ying guo sheng Min Jiangsu Key Laboratory of Advanced Metallic Materials School of Materials Science and Engineering Southeast University Mechanical Engineering Louisiana State University

This paper presents a simple and cost-effective method for the production of micro-sized silicon carbide whiskers at high yield and the effect on heat transfer enhancement for the whisker laden fluids. For SiC whisker synthesis, the starting powder mix- ture is obtained by milling short carbon fibers with the white ashes of rice hulls. Calcina：ion in argon, together with the subse- quent purification process, results in a high yield of SiC whiskers, which possess a diameter of 200-400 nm and a length of several tens of microns. The formation of the whiskers is discussed according to VS growth mechanism. Convective heat transfer performance in small channel tubes is then studied for fluid systems mixed with those micro-sized SiC whiskers at different concentrations. The heat transfer coefficient of SiC containing fluid can be significantly improved in comparison to the base fluid.

关键词： SiC whiskers Vapor-Solid whisker suspension heat transfer

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Rapid and Sensitive LC-MS/MS Method for Quantification of Fexofenadine in Human Plasma——Application to a Bioequivalence Study in Chinese Volunteers

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Chemical Research in Chinese Universities 2007年第5期23卷 514-517页

作者： TENG guo-sheng TENG Le-sheng WU Yi TANG Yun-biao LIU Lan-ying GU Jing-kai　 Research Center for Drug Metabolism College of Life Science School of Pharmaceutical Science Jilin University Changchun 130021 P. R. China Department of Pharmacy General Hospital of Shenyang Military Command Shenyang 110016 P. R. China

A rapid and sensitive liquid chromatography-tandem mass spectrometry method（LC-MS/MS）was developed and validated for the quantification of fexofenadine in human plasma,to conduct comparative bioavailability *** plasma was extracted with a mixture of dichloromethane-diethyl ether（volume ratio 2∶3）in a basic environment and the extract was separated on a C18 column with a mobile phase consisting of acetonitrile-methanol-10 mmol/L ammonium acetate（volume ratio 45∶45∶10）.The analytes were detected via electrospray ionization（ESI）tandem mass spectrometry in the multiple-reaction-monitoring（MRM）*** linearity was within a range of 1-1000 ng/*** intra-and inter-day precision were〈4.1% and〈4.8%,respectively,and the accuracy was in the range of 95.0%-105%.The method was applied to the quantification of fexofenadine human plasma from 20 healthy male Chinese volunteers,according to a single dose,randomized,two-way crossover design with a two-week washout *** mean values of major pharmacokinetic parameters of ρmax,AUC0-48,AUC0-∞,tmax,and t1/2 were determined from the plasma *** analysis of variance（ANOVA）did not show any significant difference between the two products of fexofenadine and 90% confidence intervals fell within the acceptable range for bioequivalence.

关键词： Fexofenadine Bioequivalence LC-MS/MS Human plasma

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Research on Inorganic Anion Recognition of Calix[4]pyrroles and Dipyrrylmethanes by Capillary Zone Electrophoresis

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Chinese Journal of Chemistry 2005年第11期23卷 1515-1518页

作者： ZHOU, Chang-Zheng QIU, Hong-Deng guo, Yong JIANG, sheng-Xiang Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical Physics Graduate School of the Chinese Academy of Sciences Lanzhou Gansu 730000 China

Capillary electrophoresis （CE） can separate charged and neutral substances with high speed and efficiency. In this paper, utilizing meso-octamethylcalix[4]pyrrole, meso-tetraspirocyclohexylcalJx[4]pyrrole, bimethyl bi（2-pyrryl）- methane and 1,1-bi（2-pyrryl）cyclohexane as additives in capillary zone electrophoresis （CZE） electrolyte, their recognition ability to inorganic anions was discussed. The dipyrrylmethanes have better recognition ability than others. Their effects on separation of seven normal inorganic anions by CZE were studied.

关键词： calixpyrrole dipyrrylmethane anion recognition capillary electrophoresis inorganic anion

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