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Stacking MoS_(2) flower-like microspheres on pomelo peels-derived porous carbon nanosheets for high-efficient X-band electromagnetic wave absorption

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Nano Research 2024年第3期17卷 1607-1615页

作者： jia Zhao Zhe gu Qingguo Zhang College of Chemistry and Materials Engineering Bohai UniversityJinzhou 121013China

The key to solve increasingly severe electromagnetic(EM)pollution is to explore sustainable,easily prepared,and cost-effective EM wave absorption materials with exceptional absorption ***,instead of anchoring on carbon materials in single layer,MoS_(2) flower-like microspheres were stacked on the surface of pomelo peels-derived porous carbon nanosheets(C)to fabricate MoS_(2)@C nanocomposites by a facile solvothermal *** wave absorption performances of MoS_(2)@C nanocomposites in X-band were systematically investigated,indicating the minimum reflection loss(RLmin)of-62.3 dB(thickness of 2.88 mm)and effective absorption bandwidth(EAB)almost covering the whole X-band(thickness of 2.63 mm)with the filler loading of only 20 wt.%.Superior EM wave absorption performances of MoS_(2)@C nanocomposites could be attributed to the excellent impedance matching characteristic and dielectric loss capacity(conduction loss and polarization loss).This study revealed that the as-prepared MoS_(2)@C nanocomposites would be a novel prospective candidate for the sustainable EM absorbents with superior EM wave absorption performances.

关键词： pomelo peels-derived porous carbon nanosheets(C) MoS_(2)@C nanocomposites stacked structure electromagnetic(EM)wave absorption

Nuclear transport receptors underpin plastidial retrograde signaling

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Molecular Plant 2024年第7期17卷 993-995页

作者： Min jia Yangnan gu Department of Plant and Microbial Biology University of CaliforniaBerkeleyBerkeleyCAUSA

The nucleus integrates cytosolic and organellar signals to regulate gene expression during plant stress responses,and this process is highly dependent on shuttling of signaling molecules in and out of the *** nucleocytoplasmic transport of macromolecules is facilitated by nuclear transport receptors(NTRs).NTRs are broadly categorized into exportins,which mediate the export of cargo from the nucleus to the cytoplasm,and importins,which facilitate the import of cargo into the *** importin family comprises importin-α(IMPa)and importin-β(IMPp).IMPa proteins are adaptor proteins and composed of three functional domains:an N-terminal IMPβ-binding(IBB)domain,ten Armadillo(ARM)repeats responsible for recognizing and interacting with cargo,and an exportin-interacting domain crucial for recycling via nuclear export(Wing et al.,2022).During a nuclear transport event,*** cargo containing a classical nuclear localization signal(cNLS)through its ARM repeats and engages IMPβvia its IBB domain,forming the cargo-IMPa-IMPβternary ***βfacilitates translocation of this complex through the nuclear *** inside the nucleus,RanGTP competes with IMPa for binding to IMPβ,promoting disassembly of the transport complex and releaseofcargo.

关键词： complex. integrate ternary

Temporal and spatial regulation of biomimetic vascularization in 3D-printed skeletal muscles

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Bio-Design and Manufacturing 2024年第5期7卷 597-610页

作者： Minxuan jia Tingting Fan Tan jia xin Liu Heng Liu Qi gu Key Laboratory of Organ Regeneration and Reconstruction State Key Laboratory of Membrane BiologyInstitute of ZoologyChinese Academy of SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Department of Orthopaedics Beijing Jishuitan HospitalCapital Medical UniversityBeijing 100035China

In the intricate skeletal muscle tissue,the symbiotic relationship between myotubes and their supporting vasculature is pivotal in delivering essential oxygen and *** study explored the complex interplay between skeletal muscle and endothelial cells in the vascularization ofmuscle *** harnessing the capabilities of three-dimensional(3D)bioprinting and modeling,we developed a novel approach involving the co-construction of endothelial and muscle cells,followed by their subsequent *** findings highlight the importance of the interaction dynamics between these two cell ***,introducing endothelial cells during the advanced phases of muscle differentiation enhanced myotube ***,it stimulated the development of the vascular network,paving the way for the early stages of vascularized skeletal muscle *** methodology proposed in this study indicates the potential for constructing large-scale,physiologically aligned skeletal ***,it highlights the need for exploring the delicate equilibrium and mutual interactions between muscle and endothelial *** on the multicell-type interaction model,we can predict promising pathways for constructing even more intricate tissues or organs.

关键词： Skeletal muscle Vascularization 3D bioprinting Cell interaction

Unleashing the Power of Bio-based Thermotropic Liquid Crystal Modifiers:Toughening and Reinforcing Petroleum-based Epoxy Resin without Compromising Other Properties

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Chinese Journal of Polymer Science 2024年第8期42卷 1093-1102页

作者： Qing-Yun Lu Hong-Wei gu jia-Hui Li Qian-Qian Fan Bei-Tao Liu Yan Kou xi-Gao jian Zhi-Huan Weng State Key Laboratory of Fine Chemicals Frontiers Science Center for Smart MaterialsLiaoning Technology Innovation Center of High Performance Resin MaterialsDepartment of Polymer Science&EngineeringDalian University of TechnologyDalian 116024China Thermochemistry Laboratory Liaoning Province Key Laboratory of Thermochemistry for Energy and MaterialsDalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China

Toughening the petroleum-based epoxy resin blends with bio-based modifiers without compromising their modulus,mechanical strength,and other properties is still a big challenge in view of the *** this study,a bio-based liquid crystal epoxy resin(THMT-E P)with an s-triazine ring structure was utilized to modify a petroleum-based bisphenol A epoxy resin(E51)with 4,4'-diaminodiphenylsulfone(DDS)as a curing agent,and the blended systems were evaluated for their thermal stability,mechanical properties,and flame *** results showed that the impact strength of the blended system initially increased and then decreased with the increase in THMT-EP content,and it reached the a maximum value of 26.5 kJ/m^(2)when the THMT-EP content was 5%,which was 31.2%higher than that of E51/***,the flexural strength,modulus,and glass transition tem perature of the blended system were all simultaneously improved with the addition of *** the same time,the addition of THMT-EP enhanced the flame retardancy of the system by increasing the char yield at 700℃and decreasing the peak heat release rate and total heat release *** work paves the way for a more sustainable improvement in the comprehensive performance of epoxy resin.

关键词： Epoxy resin Toughening Bio-based Thermotropic liquid crystal

Flexible and Robust Functionalized Boron Nitride/Poly(p‑Phenylene Benzobisoxazole)Nanocomposite Paper with High Thermal Conductivity and Outstanding Electrical Insulation

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Nano-Micro Letters 2024年第2期16卷 423-437页

作者： Lin Tang Kunpeng Ruan xi Liu Yusheng Tang Yali Zhang Junwei gu Chongqing Key Laboratory of Green Synthesis and Applications College of ChemistryChongqing Normal UniversityChongqing 401331People’s Republic of China Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China

With the rapid development of 5G information technology,thermal conductivity/dissipation problems of highly integrated electronic devices and electrical equipment are becoming *** this work,“high-temperature solid-phase&diazonium salt decomposition”method is carried out to prepare benzidine-functionalized boron nitride(m-BN).Subsequently,m-BN/poly(pphenylene benzobisoxazole)nanofiber(PNF)nanocomposite paper with nacremimetic layered structures is prepared via sol–gel film transformation *** obtained m-BN/PNF nanocomposite paper with 50 wt%m-BN presents excellent thermal conductivity,incredible electrical insulation,outstanding mechanical properties and thermal stability,due to the construction of extensive hydrogen bonds andπ–πinteractions between m-BN and PNF,and stable nacre-mimetic layered ***λ∥andλ_(⊥)are 9.68 and 0.84 W m^(-1)K^(-1),and the volume resistivity and breakdown strength are as high as 2.3×10^(15)Ωcm and 324.2 kV mm^(-1),***,it also presents extremely high tensile strength of 193.6 MPa and thermal decomposition temperature of 640°C,showing a broad application prospect in high-end thermal management fields such as electronic devices and electrical equipment.

关键词： Poly(p-phenylene-2,6-benzobisoxazole)nanofiber Boron nitride Thermal conductivity Electrical insulation

A Comprehensive Study of the Association between LEPR Gene rs1137101 Variant and Risk of Digestive System Cancers

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Biomedical and Environmental Sciences 2024年第5期37卷 445-456页

作者： HU Wei Qiong ZHOU Wei guang ZHOU guang Wei LIAO jia xi SHI jia xing xiE FengYang LI Shou Heng WANG Yong FENG xian Hong gu xiu Li CHEN Bi Feng Department of Biological Science and Technology School of ChemistryChemical Engineering and Life SciencesWuhan University of TechnologyWuhan 430070HubeiChina Institute of WUT-AMU Wuhan University of TechnologyWuhan 430070HubeiChina Department of Clinical Laboratory Wuhan Xinzhou District People’s HospitalWuhan 430499HubeiChina Department of Reproductive Genetics Wuhan Huake Reproductive HospitalWuhan 430013HubeiChina

Objective The leptin receptor,encoded by the LEPR gene,is involved in tumorigenesis.A potential functional variant of LEPR,rs1137101(Gln223Arg),has been extensively investigated for its contribution to the risk of digestive system(DS)cancers,but results remain conflicting rather than ***,we performed a case–control study and subsequent meta-analysis to examine the association between rs1137101 and DS cancer *** A total of 1,727 patients with cancer(gastric/liver/colorectal:460/480/787)and 800 healthy controls were *** of rs1137101 was conducted using a polymerase chain reactionrestriction fragment length polymorphism(PCR-RFLP)assay and confirmed using Sanger ***-four eligible studies were included in the *** After Bonferroni correction,the case–control study revealed that rs1137101 was significantly associated with the risk of liver cancer in the Hubei Chinese *** meta-analysis suggested that rs1137101 is significantly associated with the risk of overall DS,gastric,and liver cancer in the Chinese *** The LEPR rs1137101 variant may be a genetic biomarker for susceptibility to DS cancers(especially liver and gastric cancer)in the Chinese population.

关键词： LEPR gene rs1137101 Digestive system cancers Genetic susceptibility Meta-analysis

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中韩梁祝传说比较研究

中南民族大学学报（人文社会科学版） 2006年第6期26卷 48-53页

作者：顾希佳杭州师范学院历史文化研究所浙江杭州310012

本文通过中韩梁祝传说大量异文的比较研究,指出相互之间的不同之处,即韩国梁祝传说中经常出现的“柳叶传情”、“腐衣殉情”等情节单元,在中国梁祝传说中十分罕见;而中国梁祝传说中的“十八相送”、“楼台相会”等情节单元,以及人们不... 详细信息

本文通过中韩梁祝传说大量异文的比较研究,指出相互之间的不同之处,即韩国梁祝传说中经常出现的“柳叶传情”、“腐衣殉情”等情节单元,在中国梁祝传说中十分罕见;而中国梁祝传说中的“十八相送”、“楼台相会”等情节单元,以及人们不习惯讲述梁祝完整故事而只讲述其中某个片断,并由许多小故事构成庞大故事群的叙事样式,在韩国梁祝传说中也很少出现。最后还分析了造成差异的原因。

关键词：梁祝传说口头叙事比较研究

Combining lymph node ratio to develop prognostic models for postoperative gastric neuroendocrine neoplasm patients

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3507-3520页

作者： Wen Liu Hong-Yu Wu jia-xi Lin Shu-Ting Qu Yi-Jie gu Jin-Zhou Zhu Chun-Fang Xu Department of Gastroenterology Changzhou Hospital of Traditional Chinese MedicineChangzhou 213000Jiangsu ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina Department of Gastroenterology Suzhou Ninth Hospital Affiliated to Soochow UniversitySuzhou 215200Jiangsu ProvinceChina

BACKGROUND Lymph node ratio(LNR)was demonstrated to play a crucial role in the prognosis of many ***,research concerning the prognostic value of LNR in postoperative gastric neuroendocrine neoplasm(NEN)patients was *** To explore the prognostic value of LNR in postoperative gastric NEN patients and to combine LNR to develop prognostic *** A total of 286 patients from the Surveillance,Epidemiology,and End Results database were divided into the training set and validation set at a ratio of 8:2.92 patients from the First Affiliated Hospital of Soochow University in China were designated as a test *** regression analysis was used to explore the relationship between LNR and disease-specific survival(DSS)of gastric NEN *** survival forest(RSF)algorithm and Cox proportional hazards(CoxPH)analysis were applied to develop models to predict DSS respectively,and compared with the 8th edition American Joint Committee on Cancer(AJCC)tumornode-metastasis(TNM)*** Multivariate analyses indicated that LNR was an independent prognostic factor for postoperative gastric NEN patients and a higher LNR was accompanied by a higher risk of *** RSF model exhibited the best performance in predicting DSS,with the C-index in the test set being 0.769[95%confidence interval(CI):0.691-0.846]outperforming the CoxPH model(0.744,95%CI:0.665-0.822)and the 8th edition AJCC TNM staging(0.723,95%CI:0.613-0.833).The calibration curves and decision curve analysis(DCA)demonstrated the RSF model had good calibration and clinical ***,the RSF model could perform risk stratification and individual prognosis prediction *** A higher LNR indicated a lower DSS in postoperative gastric NEN *** RSF model outperformed the CoxPH model and the 8th edition AJCC TNM staging in the test set,showing potential in clinical practice.

关键词： Gastric neuroendocrine neoplasm Lymph node ratio Disease-specific survival Random survival forest Predictive model

Emerging clinical relevance of microbiome in cancer:promising biomarkers and therapeutic targets

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Protein & Cell 2024年第4期15卷 239-260页

作者： jia-Hao Dai xi-Rong Tan Han Qiao Na Liu State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510050China

The profound influence of microbiota in cancer initiation and progression has been under the spotlight for years,leading to numerous researches on cancer microbiome entering clinical *** promising biomarkers and therapeutic targets,the critical involvement of microbiota in cancer clinical practice has been increasingly ***,recent progress in this field is *** describe the potential of tumor-associated microbiota as effective diagnostic and prognostic biomarkers,*** addition,we highlight the relationship between microbiota and the therapeutic efficacy,toxicity,or side effects of commonly utilized treatments for cancer,including chemotherapy,radiotherapy,and *** that microbial factors influence the cancer treatment outcome,we further summarize some dominating microbial interventions and discuss the hidden risks of these *** review aims to provide an overview of the applications and advancements of microbes in cancer clinical relevance.

关键词： microbiome cancer diagnosis prognosis therapy