Emerging clinical relevance of microbiome in cancer:promising biomarkers and therapeutic targets
作者机构：State Key Laboratory of Oncology in South ChinaGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510050China
出 版 物：《Protein & Cell》 (蛋白质与细胞（英文版）)
年 卷 期：2024年第15卷第4期
页 面：239-260页
核心收录：
学科分类：0710[理学-生物学] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by grants from the Guangzhou Science and Technology Project(202206010013 to N.Liu) the Guangdong Basic and Applied Basic Research Foundation(2022A1515220010 to N.Liu) the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(22yklj07 to N.Liu)
主 题：microbiome cancer diagnosis prognosis therapy
摘 要：The profound influence of microbiota in cancer initiation and progression has been under the spotlight for years,leading to numerous researches on cancer microbiome entering clinical *** promising biomarkers and therapeutic targets,the critical involvement of microbiota in cancer clinical practice has been increasingly ***,recent progress in this field is *** describe the potential of tumor-associated microbiota as effective diagnostic and prognostic biomarkers,*** addition,we highlight the relationship between microbiota and the therapeutic efficacy,toxicity,or side effects of commonly utilized treatments for cancer,including chemotherapy,radiotherapy,and *** that microbial factors influence the cancer treatment outcome,we further summarize some dominating microbial interventions and discuss the hidden risks of these *** review aims to provide an overview of the applications and advancements of microbes in cancer clinical relevance.
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