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Source identification and global implications of black carbon

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Geoscience Frontiers 2022年第1期13卷 404-416页

作者： Erika P.Blanco-Donado Ismael L.Schneider Paulo Artaxo Jesus Lozano-osorio Luana Portz Marcos L.S.Oliveira Department of Civil and Environmental Universidad de la CostaCUCBarranquilla080002Colombia Department of Applied Physics Institute of PhysicsUniversity of São PauloSP 05508-220Brazil Universidad de Lima Avenida Javier Prado Este 4600Santiago de Surco 1503Peru

Black carbon(BC)is one of the short-lived air pollutants that contributes significantly to aerosol radiative forcing and global climate *** is emitted by the incomplete combustion of fossil fuels,biofuels,and *** environments are quite complex and thus,the use of mobile jointly with fixed monitoring provides a better understanding of the dynamics of BC distribution in such *** present study addresses the measurement of BC concentration using real-time mobile and ambient monitoring in Barranquilla,an industrialized urban area of the Colombian Caribbean.A microaethalometer(MA200)and an aethalometer(AE33)were used for measuring the BC *** absorption Ångström exponent(AAE)values were determined for the study area,for identifying the BC emission *** results of the ambient sampling show that vehicle traffic emissions prevail;however,the influence of biomass burning was also *** mean ambient BC concentration was found to be 1.04±1.03μg/m^(3) and varied between 0.5 and 4.0μg/m^(3).From the mobile measurements obtained in real traffic conditions on the road,a much higher average value of 16.1±16.5μg/m^(3) was *** parts of the city showed BC concentrations higher than 20μg/m^(3).The spatial distribution of BC concentration shows that vehicle emissions and traffic jams,a consequence of road and transport infrastructure,are the factors that most affect the BC concentration.A comparison of results obtained from two aethalometers indicates that the concentrations measured by MA200 are 9%lower than those measured by *** AAE obtained was found to vary between 1.1 and 1.6,indicating vehicular emissions as the most crucial *** addition,it was observed that the BC concentration on working days was 2.5 times higher than on the weekends in the case of mobile monitoring and 1.5 times higher in the case of ambient monitoring.

关键词： Air pollution Black carbon Spatial distribution Source apportionment AbsorptionÅngström exponent

Modern data sources and techniques for analysis and forecast of road accidents:A review

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第4期7卷 432-446页

作者： Camilo Gutierrez-osorio Cesar Pedraza Departamento de Ingeniena de Sistemas e Industrial Universidad Nacional de ColombiaBogotaColombia

Road accidents are one of the most relevant causes of injuries and death worldwide,and therefore,they constitute a significant field of research on the use of advanced algorithms and techniques to analyze and predict traffic accidents and determine the most relevant elements that contribute to road *** research of road accident prediction aims to respond to the challenge of offer tools to generate a more secure mobility environment,and ultimately,save *** paper aims to provide an overview of the state of the art in the prediction of road accidents through machine learning algorithms and advanced techniques for analyzing information,such as convolutional neural networks and long short-term memory networks,among other deep learning ***,in this article,a compendium and study of the most used data sources for the road accident forecast is *** a classification is proposed according to its origin and characteristics,such as open data,measurement technologies,onboard equipment and social media *** the analysis of the information,the different algorithms employed to make predictions about road accidents are listed and compared,as well as their applicability depending on the types of data being analyzed,along with the results obtained and their ease of interpretation and *** best results reported by the authors are obtained when two or more analytic techniques are combined,in such a way that analysis of the obtained results is *** the future challenges in road traffic forecasting lies the enhancement of the scope of the proposed models and predictions by the incorporation of heterogeneous data sources,that include geo spatial data,information from traffic volume,traffic statistics,video,sound,text and sentiment from social media,that many authors concur that can improve the precision and accuracy of the analysis and predictions.

关键词： Traffic engineering Data analysis Machine learning Road accident forecasting Traffic accident prediction

Unplanned surgery of congenital scoliosis

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Chinese Medical Journal 2022年第3期135卷 374-376页

作者： Huiliang Yang Gihye Im Ce Zhu Camilo osorio Umar Masood Chunguang Zhou Xi Yang Limin Liu Yueming Song Department of Orthopedics Orthopedic Research InstituteWest China HospitalSichuan UniversityChengduSichuan 610041China Department of Emergency Medicine Rhode Island HospitalWarren Alpert Medical School of Brown UniversityProvidenceRI 02903USA Department of Orthopedics Rhode Island HospitalWarren Alpert Medical School of Brown UniversityProvidenceRI 02903USA

To the Editor:There is a high probability of requiring unplanned surgery for congenital scoliosis(CS),but very few publications have reported the proportion of unplanned surgeries,the causes of those unplanned surgeries,and the prevalence of each *** study aimed to provide more information regarding the *** reviewed the electronic medical records of patients with CS that underwent unplanned surgeries at our hospital from 2009 to *** searching the database of West China Hospital,we found 317 CS *** these,33 cases underwent unplanned surgeries,of which five had their primary surgeries at outside *** unplanned surgery rate in our case series was 9.0%(28/312).In our case series,the most common cause of unplanned surgery for patients with CS was progressive deformity(49%,16/33),followed by implant-related complications(36%,12/33),wound-related complications(12%,4/33),and surgical error-related complications(cerebrospinal fluid[CSF]leak,3%,1/33).The most common reason for unplanned surgery in CS was progressive spinal deformity or imbalance,which accounted for 49%(16/33)of the unplanned surgeries.

关键词： surgery congenital wound

Epigenetic interventions for brain rejuvenation：anchoring age-related transposons

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Neural Regeneration Research 2018年第4期13卷 635-636页

作者： Adonis Sfera Lisa Fayard Carolina osorio Amy Price Department of Psychiatry Patton State HospitalPattonCAUSA Department of Psychiatry Loma Linda UniversityLoma LindaCAUSA Evidence-Based Medicine University of OxfordOxfordUK

Highlights：*** and homocysteine accumulation in aging neurons alter genomic *** altered methylome reactivates neuronal cell cycle,enabling transposable element *** R29/p53 axis restores age-related methylation shifts... 详细信息

关键词： Epigenetic interventions for brain rejuvenation:anchoring age-related transposons PUFAs DNA Figure TE cycle

NADPH oxidases： an overview from structure to innate mmunity-associated pathologies

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Cellular & Molecular Immunology 2015年第1期12卷 5-23页

作者： Arvind Panday Malaya K Sahoo Diana osorio Sanjay Batra Department of Pathobiological Sciences School of Veterinary Medicine Louisiana State University Baton Rouge LA USA Department of Pathology Stanford University School of Medicine Stanford CA USA Department of Environmental Toxicology Southern University and A&M College BatonRouge Louisiana 70813 Department of Biological Sciences Louisiana State University Baton Rouge LA 70803 USA

Oxygen-derived free radicals, collectively termed reactive oxygen species （ROS）, play important roles in immunity, cell growth, and ceil signaling. In excess, however, ROS are lethal to cells, and the overproduction of these molecules leads to a myriad of devastating diseases. The key producers of ROS in many cells are the NOX family of NADPH oxidases, of which there are seven members, with various tissue distributions and activation mechanisms. NADPH oxidase is a multisubunit enzyme comprising membrane and cytosolic components, which actively communicate during the host responses to a wide variety of stimuli, including viral and bacterial infections. This enzymatic complex has been implicated in many functions ranging from host defense to cellular signaling and the regulation of gene expression. NOX deficiency might lead to immunosuppression, while the intracellular accumulation of ROS results in the inhibition of viral propagation and apoptosis. However, excess ROS production causes cellular stress, leading to various lethal diseases, including autoimmune diseases and cancer. During the later stages of injury, NOX promotes tissue repair through the induction of angiogenesis and cell proliferation. Therefore, a complete understanding of the function of NOX is important to direct the role of this enzyme towards host defense and tissue repair or increase resistance to stress in a timely and disease-specific manner.

关键词： alcohol COPD NLRs NOX TLRs

Whole lesion histogram analysis of apparent diffusion coefficient predicts therapy response in locally advanced rectal cancer

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World Journal of Gastroenterology 2022年第23期28卷 2609-2624页

作者： Mayra Evelia Jiménez de los Santos Juan Armando Reyes-Pérez Victor Domínguez osorio Yolanda Villaseñor-Navarro Liliana Moreno-Astudillo Itzel Vela-Sarmiento Isabel Sollozo-Dupont Department of Radiology National Cancer InstituteMexico 14080Mexico Department of Gastrointestinal Surgery National Cancer InstituteMexico 14080Mexico

BACKGROUND Whole-tumor apparent diffusion coefficient(ADC)histogram analysis is relevant to predicting the neoadjuvant chemoradiation therapy(nCRT)response in patients with locally advanced rectal cancer(LARC).AIM To evaluate the performance of ADC histogram-derived parameters for predicting the outcomes of patients with *** This is a single-center,retrospective study,which included 48 patients with *** patients underwent a pre-treatment magnetic resonance imaging(MRI)scan for primary tumor staging and a second restaging MRI for response *** sample was distributed as follows:18 responder patients(R)and 30 non-responders(non-R).Eight parameters derived from the whole-lesion histogram analysis(ADCmean,skewness,kurtosis,and ADC10^(th),25^(th),50^(th),75^(th),90^(th) percentiles),as well as the ADCmean from the hot spot region of interest(ROI),were calculated for each patient before and after *** all data were compared between R and non-R using the Mann-Whitney U *** measures of diagnostic accuracy were applied:the receiver operating characteristic curve and the diagnostic odds ratio(DOR).We also reported intra-and interobserver variability by calculating the intraclass correlation coefficient(ICC).RESULTS Post-nCRT kurtosis,as well as post-nCRT skewness,were significantly lower in R than in non-R(both P<0.001,respectively).We also found that,after treatment,R had a larger loss of both kurtosis and skewness than non-R(Δ%kurtosis and Δ skewness,P<0.001).Other parameters that demonstrated changes between groups were post-nCRT ADC10^(th),Δ%ADC10^(th),Δ%ADCmean,and ROIΔ%***,the best diagnostic performance was achieved byΔ%kurtosis at a threshold of 11.85%(Area under the receiver operating characteristic curve[AUC]=0.991,DOR=376),followed by post-nCRT kurtosis=0.78×10^(-3)mm^(2)/s(AUC=0.985,DOR=375.3),Δskewness=0.16(AUC=0.885,DOR=192.2)and post-nCRT skewness=1.59×10^(-3)mm^(2)/s(AUC=0.815,DOR=168.6).Finally,intraclass corr

关键词： Apparent diffusion coefficient Diffusion-weighted imaging Histogram analysis Magnetic resonance imaging Locally advanced rectal cancer

Liposoluble vitamins A and E in kidney disease

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World Journal of Nephrology 2022年第3期11卷 96-104页

作者： Maria Helena Rojo-Trejo Ma Ludivina Robles-osorio Ernesto Sabath Nutrition School Universidad Autónoma de QuerétaroQuerétaro 76910Mexico Department of Renal Medicine Nutrition SchoolUniversidad Autónoma de QuerétaroQuerétaro 76090Mexico

Kidney disease(KD)is characterized by the presence of elevated oxidative stress,and this is postulated as contributing to the high cardiovascular morbidity and mortality in these *** KD(CKD)is related to high grade inflammatory condition and pro-oxidative state that aggravates the progression of the disease by damaging primary *** vitamins(vitamin A and E)are potent dietary antioxidants that have also anti-inflammatory and antiapoptotic *** deficits in CKD patients are a common issue,and multiple causes are related to them:Anorexia,dietary restrictions,food cooking methods,dialysis losses,gastrointestinal malabsorption,*** potential benefit of retinoic acid(RA)and α-tocopherol have been described in animal models and in some human clinical *** review provides an overview of RA andαtocopherol in KD.

关键词： Retinoic acid α-Tocopherol Oxidative stress Kidney disease Podocyte Cardiovascular disease

High refractive index of melanin in shiny occipital feathers of a bird of paradise

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Light(Science & Applications) 2015年第1期4卷 518-523页

作者： Doekele G Stavenga Hein L Leertouwer Daniel C osorio Bodo D Wilts Computational Physics University of Groningen9747 AGThe Netherlands School of Life Sciences University of SussexBrightonBN19QGUK Adolphe Merkle Institute University of FribourgCH-1700 FribourgSwitzerland

Male Lawes’s Parotia,a bird of paradise,use the highly directional reflection of the structurally colored,brilliant-silvery occipital feathers in their courtship *** in other birds,the structural coloration is produced by ordered melanin *** barbules of the Parotia’s occipital feathers,with thickness,3 μm,contain 6–7 layers of densely packed melanin rodlets(diameter,0.25 μm,length,2 μm).The effectively,0.2 μm thick melanin layers separated by,0.2 μm thick keratin layers create a multilayer interference *** measurements yielded peak wavelengths in the near-infrared at,1.3 μm,i.e.,far outside the visible wavelength *** the Jamin-Lebedeff interference microscopy method recently developed for pigmented media,we here determined the refractive index of the intact *** thus derived the wavelength dependence of the refractive index of the barbules’melanin to be 1.7–1.8 in the visible wavelength *** the anatomical and refractive index data in an optical multilayer model,we calculated the barbules’reflectance,transmittance and absorptance spectra,thereby confirming measured spectra.

关键词： bird of paradise interference reflector iridescence Jamin-Lebedeff microscopy multilayer

Chronic urticaria associated with lung adenocarcinoma—a paraneoplastic manifestation:A case report and literature review

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World Journal of Clinical Cases 2022年第21期10卷 7553-7564页

作者： Luisa Fernanda Jiménez Evis Adriana Castellón Juan David Marenco JoséMaria Mejía Camilo Andrés Rojas Franklin Torres Jiménez Linda Coronell Estefanie osorio-Llanes Evelyn Mendoza-Torres Faculty of Health Sciences Universidad Libre de ColombiaSeccional BarranquillaBarranquilla 08000Colombia Faculty of Exact and Natural Sciences Universidad Libre de ColombiaSeccional BarranquillaBarranquilla 08000Colombia lty of Health Sciences Universidad Libre De ColombiaSeccional BarranquillaBarranquilla 08000AtlánticoColombia

BACKGROUND Urticaria is one of the most common causes of emergency room *** is defined as an acute inflammatory dermatosis,characterized by localized degranulation of mast cells,with consequent dermal microvascular and formation of edematous and pruritic plaques called *** affects the skin and tissues of the superficial *** it is accompanied by angioedema,which is characterized by deeper edema of the dermis and subcutaneous cellular tissue known as the urticarial-angioedema *** 15%-25%of the general population has suffered at least one type of urticaria at some point during their lifetime and hyperpermeability estimated at 7.6%-16%and has experienced acute urticaria that is usually self-limited and spontaneously resolves without requiring medical *** SUMMARY We present the case of a young male patient who was referred to our department with a clinical picture of 4 mo of pruritus associated with hives of variable sizes,irregular borders,with interlesional confluence,that were non-painful,without involvement of the palms and soles of the feet but with a tendency to progression in a generalized *** had multiple emergency room visits and poor response to antihistamines and systemic *** studies demonstrated nodules in the lower lingula segment,at the level of the greater fissure and in the anterior contour of the left anterior basal segment associated with parahiliar adenopathies in the absence of findings suggestive of infectious or autoimmune *** lobectomy was performed by thoracoscopy with resection of a lung nodule in the lingula and biopsy of the para-aortic mediastinal *** histopathological report showed the presence of poorly differentiated invasive adenocarcinoma with a solid morphological and acinar pattern with immunohistochemical description of lung tissue that expresses strong positive and diffuse reaction for thyroid transcription factor 1(TTF-1)with negati

关键词： Urticaria Lung adenocarcinoma Undifferentiated carcinoma Paraneoplastic syndromes Thyroid nuclear factor 1 Case report