Liposoluble vitamins A and E in kidney disease

作     者：Maria Helena Rojo-Trejo Ma Ludivina Robles-Osorio Ernesto Sabath 

作者机构：Nutrition SchoolUniversidad Autónoma de QuerétaroQuerétaro 76910Mexico Department of Renal MedicineNutrition SchoolUniversidad Autónoma de QuerétaroQuerétaro 76090Mexico 

出 版 物：《World Journal of Nephrology》 (世界肾病学杂志（英文版）)

年 卷 期：2022年第11卷第3期

页      面：96-104页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Retinoic acid α-Tocopherol Oxidative stress Kidney disease Podocyte Cardiovascular disease 

摘      要：Kidney disease(KD)is characterized by the presence of elevated oxidative stress,and this is postulated as contributing to the high cardiovascular morbidity and mortality in these *** KD(CKD)is related to high grade inflammatory condition and pro-oxidative state that aggravates the progression of the disease by damaging primary *** vitamins(vitamin A and E)are potent dietary antioxidants that have also anti-inflammatory and antiapoptotic *** deficits in CKD patients are a common issue,and multiple causes are related to them:Anorexia,dietary restrictions,food cooking methods,dialysis losses,gastrointestinal malabsorption,*** potential benefit of retinoic acid(RA)and α-tocopherol have been described in animal models and in some human clinical *** review provides an overview of RA andαtocopherol in KD.