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Biome.ical and e.vironme.tal Scie.ce. 1998年第1期11卷 46-60页

作者： fernando e. viteri(De.ortme.t of Nutrilional Scie.ce. and Toxicology, Unive.sity ofCalifornia at Be.ke.e. and Unite. Nations Ulive.sity,Be.ke.e. 94720, Chlifornia, USA) De.artme.t of Nutritional Scie.ce. and Toxicology University of California at Berkeley USA.

Iron de.icie.cy (ID), de.ine. as an insufficie.t supply of iron to the.ce.ls of the.body afte. iron re.e.ve. have.be.n e.hauste., is the.most pre.ale.t single.nutritional de.icie.cy, affe.ting ove. 2, 000 million pe.ple. mostly in the.de.e.oping world. Infants, small childre., adole.ce.ts and pre.nant and fe.tile.age.wome. are.most vulne.able. Only about 50 % of pe.ple.with ID de.e.op iron de.icie.cy ane.ia (IDA), since.this is a late.manife. tation of chronic ID. Base. on the.ave.age.daily iron re.uire.e.t and on the.rate.of iron re.tilization from re. ce.l he.oglobin de.truction, it can be.e.timate. that afte. iron store. have.be.n de.le.e., it take. about 4 months of ID e.ythropoie.is for adult wome. to have.a drop in he.oglobin conce.tration [Hb] of 10 g/l, if the.iron intake.is only 70 % of re.uire.e.t. IDA can be.de.ine. by a [Hb] be.ow an appropriate.cut-off point for age.se., physiological condition and altitude.above.se. le.e., or by a [Hb] incre.e.t of more.han 10 g/l to the.administration of ade.uate.dose. of iron. More.than 85 % of the.nutritional ane.ias are.IDA alone. or of iron combine. with folate.or othe. nutrie.t de.icie.cie. [WHO/UNICe./UNU, 1997; Yip, 1994].

关键词： A Ne. Conce.t in the.Control of Iron De.icie.cy ACC

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间隔补铁大鼠的肠粘膜铁含量及其生物利用率

营养学报 1993年第2期15卷 180-184页

作者：刘戌年 fernando e.viteri 新疆昌吉州人民医院昌吉831100 De.artme.t of Nutritional Scie.ce. University of CaliforniaBerkeleyUSA

雄性SD断奶大鼠32只,随机分为缺铁和铁正常两组。喂纯合成饲料,铁含量分别为0与0.8mg,每日两次喂饲。12天后再各分为每日补铁组与间隔三日补铁组,铁剂量每日与每间隔三日均为8mg,同前方式两次喂饲。于第一次补铁时喂入^(59)Fe.3.7×10~... 详细信息

雄性SD断奶大鼠32只,随机分为缺铁和铁正常两组。喂纯合成饲料,铁含量分别为0与0.8mg,每日两次喂饲。12天后再各分为每日补铁组与间隔三日补铁组,铁剂量每日与每间隔三日均为8mg,同前方式两次喂饲。于第一次补铁时喂入^(59)Fe.3.7×10~4Bq。18天后杀死大鼠,对十二指肠与小肠各段粘膜铁、肠腔遗留铁及其^(59)Fe.cpm)进行检测,并计算出^(59)Fe.用率。结果表明,每日补铁组肠粘膜与肠腔遗留铁分别为铁正常对照组的8与20倍。^(59)Fe.用率为其1/2。间隔补铁组肠粘膜铁接近铁正常对照组,^(59)Fe.用率为其2倍,肠腔内遗留铁仅为每日补铁组1/5。间隔外铁组补铁剂量小,副作用明显少于每日补铁组,肠粘膜铁吸收与利用比较理想。

关键词：间隔补铁小肠粘膜铁铁生物利用率

e.Comme.ce.Fraud De.e.tion Base. on Machine.Le.rning Te.hnique.:Syste.atic Lite.ature.Re.ie.

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Big Data Mining and Analytics 2024年第2期7卷 419-444页

作者： Abe. Mute.i fernando Bacao NOVA Information Manage.e.t School(NOVA IMS) Universidade Nova de LisboaCampus de CampolideLisboa 1070-312Portugal

The.e.comme.ce.industry’s rapid growth,acce.e.ate. by the.COVID-19 pande.ic,has le. to an alarming incre.se.in digital fraud and associate. *** e.tablish a he.lthy e.comme.ce.e.osyste.,robust cybe. se.urity and anti-fraud me.sure. are.***,re.e.rch on fraud de.e.tion syste.s has struggle. to ke.p pace.due.to limite. re.l-world *** in artificial inte.lige.ce.Machine.Le.rning(ML),and cloud computing have.re.italize. re.e.rch and applications in this *** ML and data mining te.hnique. are.popular in fraud de.e.tion,spe.ific re.ie.s focusing on the.r application in e.comme.ce.platforms like.e.ay and Face.ook are.lacking *** re.ie.s provide.broad ove.vie.s but fail to grasp the.intricacie. of ML algorithms in the.e.comme.ce.*** bridge.this gap,our study conducts a syste.atic lite.ature.re.ie. using the.Pre.e.re. Re.orting Ite.s for Syste.atic re.ie.s and Me.a-Analysis(PRISMA)*** aim to e.plore.the.e.fe.tive.e.s of the.e.te.hnique. in fraud de.e.tion within digital marke.place. and the.broade. e.comme.ce.*** the.curre.t state.of the.lite.ature.and e.e.ging tre.ds is crucial give. the.rising fraud incide.ts and associate. *** our inve.tigation,we.ide.tify re.e.rch opportunitie. and provide.insights to industry stake.olde.s on ke. ML and data mining te.hnique. for combating e.comme.ce.*** pape. e.amine. the.re.e.rch on the.e.te.hnique. as publishe. in the.past *** the.PRISMA approach,we.conducte. a conte.t analysis of 101 publications,ide.tifying re.e.rch gaps,re.e.t te.hnique.,and highlighting the.incre.sing utilization of artificial ne.ral ne.works in fraud de.e.tion within the.industry.

关键词： e.comme.ce Machine.Le.rning(ML) syste.atic re.ie. fraud de.e.tion organize. re.ail fraud

e.fe.t of particle.Froude.numbe. on sub-grid e.fe.tive.drag,filte.e. and re.idual stre.se. in fluidize. gas-particle.flows

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Particuology 2024年第12期95卷 36-48页

作者： Christian C.Milioli fernando e.Milioli De.artme.t of Me.hanical e.gine.ring School of Engineering of São CarlosUniversity of São Paulo13566-590São CarlosSPBrazil

Sub-grid e.fe.tive.drag,filte.e. and re.idual stre.se. in the.me.o-scale.of gas-particle.fluidize. flows are.intrinsically affe.te. by unde.lying micro-scale.conditions as we.l as non-local e.fe.ts re.ate. to macro-scale.*** this work we.applie. microscopic two-fluid mode.ing to e.pe.ime.t with particle.Froude.numbe. in orde. to e.aluate.the.impact of this micro-scale.condition ove. the.conce.ning me.o-scale.de.ive. sub-grid *** pe.forme. highly re.olve. simulations in pe.iodic domains for particle.Froude.numbe.s from 12.21 to 799.22,for a wide.range.of macro-scale.*** we.e.filte.e. and classifie. by range. of me.o-scale.marke.s for the.various particle.Froude.*** particle.Froude.numbe. was found to conside.ably affe.t the.structural re.ine.e.t of the.he.e.oge.e.us flow fie.ds the.e.y dire.tly impacting e.fe.tive.drag,filte.e. and re.idual *** of those.parame.e.s showe. syste.atic be.aviors in re.ation to particle.Froude.numbe.,the.e.y providing sound data for ne. sub-grid mode.ing propositions.

关键词： Fluidization Gas-particle.flows Two-fluid mode. Sub-grid analysis Multiscale.analysis

e.iomime.ic approache. toward smart bio-hybric syste.s

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Nano Re.e.rch 2018年第6期11卷 3009-3030页

作者： Zhiqiang Luo Dara e. We.ss Qingyun Liu Bozhi Tian Colle.e.of Life.Scie.ce.and Te.hnology Huazhong University of Science and Technology Wuhan 430074 China De.artme.t of Che.istry The University of Chicago Chicago IL 606d7 USA The.Jame. Franck Institute The University of Chicago Chicago IL 60637 USA The.Institute.for Biophysical Dynamics The University of Chicago Chicago IL 60637 USA

Bio-inte.rate. mate.ials and de.ice. can blur the.inte.face. be.we.n living and artificial syste.s. Microfluidics, bioe.e.tronics, and e.gine.re. nanostructure., with close.inte.actions with biology at the.ce.lular or tissue.le.e.s, have.alre.dy yie.de. a spe.trum of ne. applications. Many ne. de.igns e.e.ge. including of organ-on-a-chip syste.s, biode.radable.implants, e.e.troce.tical de.ice., minimally invasive.ne.ro-prosthe.ic tools, and soft robotics. In this re.ie., we.highlight a fe. re.e.t advance. of the.fabrication and application of smart bio-hybrid syste.s, with a particular e.phasis on the.thre.-dime.sional （3D） bio-inte.rate. de.ice. that mimic the.3D fe.ture.of tissue.scaffolds. More.ve., ne.rons inte.rate. with e.gine.re. nanostructure. for wire.e.s ne.romodulation and dynamic ne.ral output are.brie.ly discusse.. We.also discuss the.progre.s in the.construction of ce.l-e.able. soft robotics, whe.e.a tight coupling of the.synthe.ic and biological parts is crucial for e.ficie.t function. Finally, we.summarize.the.approache. for e.hancing bio-inte.ration with biomime.ic micro- and nanostructure..

关键词： bio-inte.rate. de.ice bio-hybrid syste. biomime.ics nano-bio inte.face

Be.f he.fe. fe.tility: importance.of manage.e.t practice. and te.hnological advance.e.ts

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Journal of Animal Scie.ce.and Biote.hnology 2021年第1期12卷 110-121页

作者： Sarah e.Moore. fernando H.Biase De.artme.t of Animal Scie.ce University of TennesseeKnoxvilleTNUSA De.artme.t of Animal and Poultry Scie.ce. Virginia Polytechnic Institute and State University175 West Campus DriveBlacksburgVA 24061USA.

The.de.e.opme.t of re.lace.e.t he.fe.s is at the.core.of cow-calf be.f production syste.s. In 2020, the.USDA,National Agricultural Statistics Se.vice.re.orte. 5.771 million be.f he.fe.s, 500 pounds and ove., are.unde. de.e.opme.t for cow re.lace.e.t. A compilation of data from se.e.al studie. indicate.that be.we.n 85% and 95% of the.e.he.fe.s will be.ome.pre.nant in the.r first bre.ding se.son. Se.e.al thousands of he.fe.s be.ng raise. for re.lace.e.t may not de.ive. a calf on the.r first bre.ding se.son and re.ult in e.onomic losse. to cow-calf produce.s. Many manage.e.t proce.ure. have.be.n de.e.ope. to maximize.the.re.roductive.pote.tial of be.f he.fe.s. Such approache. include. but are.not limite. to the.following: nutritional manage.e.t for controlle. we.ght gain, ide.tification of re.roductive.maturity by physiological and morphological indicators, and the.imple.e.tation of an e.trous synchronization *** imple.e.tation of manage.e.t strate.ie. has important positive.impact(s) on the.re.roductive.e.ficie.cy of *** are.limitations, howe.e., be.ause.some.he.fe.s de.me. re.dy to e.te. the.r first bre.ding se.son do not be.ome.pre.nant. In paralle., ge.e.ic se.e.tion for fe.tility-re.ate. traits in be.f he.fe.s have.not promote. major ge.e.ic gains on this particular are., most like.y due.to low he.itability of fe.ale.fe.tility traits in cattle. Te.hnologie. such as antral follicle.counting, DNA ge.otyping and RNA profiling are.be.ng inve.tigate. as a me.ns to aid in the.ide.tification of he.fe.s of low fe.tility pote.tial. To date. many polymorphisms have.be.n associate. with he.fe. fe.tility, but no DNA marke.s have.be.n ide.tifie. across he.ds. Antral follicle.count is an indication of the.ovarian re.e.ve.and is an indicator of the.re.roductive.he.lth of a he.fe.. We.have.be.n working on the.ide.tification of transcriptome.profile. in he.fe.s associate. with pre.nancy outcome. Our curre.t inve.tigations inte.rating prote.n-coding transcript abu

关键词： Be.f cattle Cow-calf Ge.omics Infe.tility

e.fe.t of Magne.ic Fie.d on a p-Type.δ-Dope. GaAs Laye.

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Chine.e.Physics Le.te.s 2010年第7期27卷 233-236页

作者： e. OZTURK De.artme.t of Physics Cumhuriyet University Sivas 58140 Turkey

The.e.e.gy le.e.s of hole. in a p-type.δ-dope. GaAs structure.unde. a magne.ic fie.d are.the.re.ically calculate. within the.frame.ork of the.e.fe.tive.mass approximation for a uniform ace.ptor distribution. The.e.e.tronic structure.is calculate. by solving the.Schrodinge. and Poisson e.uations se.f-consiste.tly. The.e.fe.t of the.magne.ic fie.d on the.pote.tial profile.change. the.de.re. of the.confine.e.t and localization, and thus this be.avior can be.use. to study the.e.syste.s in re.ions of inte.e.t, without the.ne.d to grow many diffe.e.t sample.. It is found that the.he.vy-hole.subbands contain many more.e.e.gy state. than the.light-hole.one.; the.population of the.he.vy-hole.le.e.s re.re.e.ts approximate.y 91 % of all the.carrie.s without magne.ic fie.d. With incre.sing magne.ic fie.d the.total population of the.he.vy-hole. incre.se. and the.numbe. of fille. state. change..

关键词： Magne.ic fie.d e.e.gy Fie.ds Compute.s Political syste.s

The.Asymptotics of the.He.t Se.igroup for a Ge.e.al Bounde. Domain with Mixe. Boundary Conditions

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Acta Mathe.atica Sinica,e.glish Se.ie. 2000年第4期16卷 627-636页

作者： e. M. e. Zaye. Mathe.atics De.artme.t. Faculty of Scie.ce. Zagazig Unive.sity. Zagazig. e.ypt

Small-time.asymptotics of the.trace.of the.he.t se.igroup θ（t）=Σv=1x e.p（-tμv）. whe.e.{μv} are.the.e.ge.value. of the.ue.ative.Laplacian -Δ= -Σβ=12（/xβ）2 in the.（x1, x2）-plane. is studie. for a ge.e.al bounde. domain Ω with a smooth boundary Ω. whe.e.a finite.numbe. of Dirichle.. Ne.mann and Robin boundary conditions, on the.pie.e.ise.smooth parts Γi（i=1, ..., n） of )Ω such that)Ω=∪i=1nΓ are.conside.e.. Some.ge.me.rical prope.tie. associate. with Ω are.de.e.mine.

关键词： He.t se.igroup Inve.se.proble. Mixe. boundary conditions e.ge.value.

Curre.t and future.pe.spe.tive. in the.manage.e.t and tre.tme.t of colore.tal cance.

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World Journal of Clinical Oncology 2025年第2期16卷 9-17页

作者： Sigfre.o e.Rome.o-Zoghbi e.ita Krumina fernando Lópe.-Campos Fe.ipe.Couñago De.artme.t of Radiation Oncology GenesisCare Talavera de la ReinaToledo 45600Spain De.artme.t of Radiation Oncology GenesisCare GuadalajaraGuadalajara 19004Spain De.artme.t of Radiation Oncology Hospital Universitario Ramón Y CajalMadrid 28034Spain De.artme.t of Radiation Oncology GenesisCare-Hospital Universitario Vithas Madrid La MilagrosaMadrid 28010Spain

In this e.itorial,we.re.ie.e. the.article.by Fadlallah e. al that was re.e.tly publishe. in the.World Journal of Clinical *** article.provide. a compre.e.sive.and in-de.th vie. of the.manage.e.t and tre.tme.t of colore.tal cance.(CRC),one.of the.le.ding cause. of cance.-re.ate. morbidity and mortality *** article.analyze. the.the.ape.tic modalitie. and the.r se.ue.cing,focusing on total ne.adjuvant the.apy for locally advance. re.tal *** highlighte. the.role.of immunothe.apy in tumors with high microsate.lite.instability or de.icie.t mismatch re.air,addre.sing re.e.t advance. that have.improve. prognosis and the.ape.tic re.ponse.in localize. and me.astatic *** in surgical te.hnique.,advance. radiothe.apy,and syste.ic age.ts targe.ing spe.ific mutational profile. are.also discusse.,re.le.ting on how the. re.olutionize. clinical *** tumor DNA has e.e.ge. as a promising tool for de.e.ting minimal re.idual dise.se.prognosis,and the.ape.tic monitoring,solidifying its role.in pre.ision *** re.ie. e.phasize. the.importance.of te.hnological and the.ape.tic advance.e.ts in improving clinical outcome. and pe.sonalizing CRC tre.tme.t.

关键词： Colore.tal cance. Me.astatic colore.tal cance. Total ne.adjuvant the.apy Che.oradiothe.apy Colon surge.y Re.tal surge.y Che.othe.apy Immunothe.apy

Coating of fine.y dispe.se. particle. by two-fluid nozzle

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Particuology 2018年第3期16卷 80-93页

作者： N. Hampe. e. Royde.a A. Buck e. Tsotsas The.mal Proce.s e.gine.ring Otto yon Guericke University Universitatsplatz 2 39106 Magdeburg Germany

Particle.coatings are.use. e.te.sive.y to ge.e.ate.dispe.se. solids with we.l-de.ine. prope.tie., e.g., to prote.t active.ingre.ie.ts, with most coating proce.se. using core.particle. of a diame.e. large. than 200 μm. This work contribute. to the.de.e.opme.t of a coating proce.s for fine.dispe.se. particle. （diam- e.e. le.s than 50 μm） by combining two particle.formulation proce.se., name.y, coating and spray drying. The.fe.sibility of the.ope.ation is base. on and de.onstrate. by the.innovative.application of a two-fluid nozzle. e.pe.ime.ts we.e.conducte. by using glass particle. as core.particle. and sodium be.zoate.as the.coating age.t. The.coating of fine.y dispe.se. particle. is achie.e. by the.spraying of particle. and coating solution as a homoge.e.us suspe.sion. The.aim is to cre.te.drople.s with only one.containe. particle.at the.nozzle.outle.. Afte. e.aporation of the.wate. in the.drople., a thin solid film is built on the.particle.surface. The.suspe.sion viscosity was me.sure. and compare. with e.pirical e.uations from the.lite.ature. The.liquid-film thickne.s on the.particle.surface.was calculate. to pre.ict the.building of a uniform coating laye. or agglome.ate.. In this study, the.fe.sibility of pne.matic transport through the.nozzle.and an inve.tigation of the.proce.s we.e.illustrate.. The.agglome.ation fraction and de.re. of coating of the.particle.surface.we.e.analyze. optically by scanning e.e.tron microscopy. In this way, the.influe.ce.of diffe.e.t proce.se. and suspe.sion parame.e.s on the.product quality we.e.de.e.mine..

关键词： Coating Spray drying Fine.dispe.se. particle Two-fluid nozzle