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Chinese Chemical Letters 2017年第2期28卷 297-301页

作者： Zun-Qi liu Yang liu Yuan Chen Wu-Qiang Zhao Wei-na fang Chemical Engineering College Xinjiang Agricultural University Urumqi 830052 China

A novel inorganic-organic hybrid supramolecular compound,[（3-nitroanilinium^＋）（18-crown-6）][IO4]（CH3OH）（1）,was discovered as phase-transition materials displaying dielectric anomalous *** yellow block crystal formed by N-H…O hydrogen bonding that made contact through the cavity of 18-crown-6 was characterized by single-crystal X-ray diffraction,elemental analysis,infrared analysis,thermogravimetric analysis,differential scanning calorimetry,and potential-energy *** scanning calorimetry measurements indicate that the compound experiences a reversible phase transition at around 220 ***-dependent dielectric measurements further confirm the phase ***-energy calculations demonstrate that the phase transition occurs due to the molecular order-disorder rotation of CH3OH,whereas the space grouping of the crystal remains unchanged.

关键词： Phase transition Crystal structure Molecular rotation Dielectric anomaly

Ammonia pyrolysis oxidation excited by nanosecond pulsed discharge:Global/fluid models hybrid solution

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Journal of Energy Chemistry 2025年第1期100卷 385-396页

作者： Mingming Zhang Hanyu Wu Qi Chen Jiaxin Yang Bonan liu School of Mechanical Electronic and Control Engineering Beijing Jiaotong University China University of Petroleum

The kinetic characteristics of plasma-assisted oxidative pyrolysis of ammonia are studied by using the global/fluid models hybrid solution ***,the stable products of plasma-assisted oxidative pyrolysis of ammonia are *** results show that the consumption of NH3/O2and the production of N2/H2change linearly with the increase of voltage,which indicates the decoupling of nonequilibrium molecular excitation and oxidative pyrolysis of ammonia at low ***,the detailed reaction kinetics mechanism of ammonia oxidative pyrolysis stimulated by a nanosecond pulse voltage at low pressure and room temperature is *** on the reaction path analysis,the simplified mechanism is *** detailed and simplified mechanism simulation results are compared with experimental data to verify the accuracy of the simplified ***,based on the simplified mechanism,the fluid model of ammonia oxidative pyrolysis stimulated by the nanosecond pulse plasma is established to study the pre-sheath/sheath behavior and the resultant consumption and formation of key *** results show that the generation,development,and propagation of the pre-sheath have a great influence on the formation and consumption of *** consumption of NH3by the cathode pre-sheath is greater than that by the anode pre-sheath,but the opposite is true for OH and O（1S）.However,within the sheath,almost all reactions do not ***,by changing the parameters of nanosecond pulse power supply voltage,it is found that the electron number density,electron current density,and applied peak voltages are not the direct reasons for the structural changes of the sheath and ***,the discharge interval has little effect on the sheath structure and gas mixture *** research results of this paper not only help to understand the kinetic promotion of non-equilibrium excitation in the process of oxidative pyrolysis but also help to explore th

关键词： nanosecond pulsed discharge Ammonia Oxidative pyrolysis Fluid model Global model

Micro-strain regulation strategy to stabilize perovskite lattice based on the categories and impact of strain on perovskite solar cells

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Journal of Energy Chemistry 2025年第1期100卷 578-604页

作者： Caixia Li Wenwu liu Shiji Da Lingbin Kong Fen Ran State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of Technology School of Materials Science and Engineering Lanzhou University of Technology

Photovoltaic metal halide perovskite solar cells(PSCs) convert light to electricity more efficiently than crystalline silicon cells, and the cost of materials used to make them is lower than that of silicon *** efficiency is not a core issue affecting the application of perovskite solar cells in special *** present, stability is the major technical encounters that hinders its further commercial development. Microstrain in PSCs is currently a significant factor responsible for the device's instability. Strain-induced ion migration is widely believed to accelerate perovskite degradation even when external stimuli are ***, it is imperative to study strain to enhance the stability of PSCs. This paper reviews recent developments to understand strain's origin and effect mechanisms on performance of PSCs, including ion migration,failure behavior, defect formation, and its effect on photoelectric properties, stability, and ***, several well-known strain management strategies are systematically introduced based on the strain effect mechanism and strain engineering on the film, providing more clues for further preparation with increased stability. The manipulation of external physical strain applied from films to entire devices has been extensively studied. Furthermore, recommendations for future research directions and chemical approaches have been provided. It is emphasized that strain engineering plays a crucial role in improving the efficiency and longevity of PSCs. Tensile strain causes rapid degradation, while moderate compressive strain and external strain control could improve properties and stability. Efforts should focus on controlling compressive strain to mitigate residual tensile strain and introducing it in a controlled manner. Future research endeavors may focus on exploring these pathways to improve the efficiency and lifespan of PSCs.

关键词： Halide perovskite solar cells Strain origins Strain effects Strain management

Perioperative anesthesia management in pediatric liver transplant recipient with atrial septal defect:A case report

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World Journal of Clinical Cases 2022年第29期10卷 10638-10646页

作者： Lan liu Pei Chen Li-Li fang Li-na Yu Department of Anesthesiology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Anesthesiology Hangzhou Women's HospitalHangzhou 310008Zhejiang ProvinceChina

BACKGROUND Preoperative conditions in pediatric liver transplant recipients are understandably *** with adults,children have lesser compensatory abilities and demand greater precision during procedural *** the setting of endstage liver disease,the heightened perioperative risk of coexistent cardiovascular pathology may impact graft survival as *** for anesthesia and perioperative management are thus more rigorous,calling for individualized treatments that reflect specific cardiovascular constraints and proposed surgical *** SUMMARY Reports of perioperative anesthesia management and liver transplant prognostication in pediatric patients with concurrent atrial septal defects are ***,we detail the course of liver transplantation in a child with dual afflictions,focusing on perioperative anesthesia management and the important contributions of the anesthesiologist(pre-and perioperatively) to a positive therapeutic outcome,despite the clinical hurdles *** Children with atrial septal defects bear substantially more than customary perioperative risk during orthotopic liver transplants,given their compromised cardiopulmonary reserves and functional *** preoperative cardiovascular assessments,including use of agitated-saline contrast echocardiography(to characterize intracardiac shunting) and multidisciplinary deliberation,may offer insights into structural cardiac pathophysiologic effects and transplantrelated hemodynamic changes that impact new *** the same time,active and effective monitoring and other measures should be taken to maintain hemodynamic stability in the perioperative period,avoid entry of bubbles into the circulation,and ease congestion in newly grafted *** efforts are crucial for transplantation success and graft survival.

关键词： Pediatric liver transplant Atrial septal defect Anesthesia Case report

Dissemination of Traditional Chinese Medicine in Germany from an Intercultural Perspective: A Brief Introduction of Franz Hübotter

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Chinese Medicine and Culture 2021年第3期4卷 188-193页

作者： fang‑Chao liu Institut für Archäologische Wissenschaften Denkmalwissenschaften and KunstgeschichteOtto‑Friedrich‑Universität BambergBamberg 96047Germany

Traditional Chinese medicine(TCM)is the cultural heritage of all *** not only embodies the cultural crystallization of the region and the nation,but also performs the important mission of curing the lives,saving the sick and maintaining the health of the *** the history of the spread of Chinese medicine to the West,foreign missionaries have played an important role,and researches about this role have continued in *** the history of Chinese medicine in Germany,there is a pivotal figure named Franz Hübotter(1881-1967),who broke through the deadlock in the academic research of Chinese medicine in the 19th century in Germany,but the discussion on his contribution has been comparatively rare in *** works and translations are not only of medical value,but are also valuable historically,culturally,and *** historical development of TCM has the authenticity of history,the integrity of the environment,and the richness of the *** experts have explored and verified the value of *** and scholars are mainly concerned with the dissemination of knowledge from an intercultural *** paper provides a primitive and objective introduction to Franz Hübotter,hoping to trigger off the secondary research among scholars of different professional backgrounds and to expand professional thinking,and then get over the barriers of disciplines.

关键词： Contributions to the Knowledge of Chinese and Tibetan Mongolian Pharmacology Franz Hübotter traditional Chinese medicine

Telomere elongation in parthenogenetic stem cells

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Protein & Cell 2014年第1期5卷 8-11页

作者： Yu Yin na liu Xiaoying Ye Renpeng Guo Jie Hao fang Wang Lin liu State Key Laboratory of Medicinal Chemical Biology Department of Cell Biology and GeneticsCollege of Life SciencesNankai UniversityTianjin 300071China

Dear Editor, Parthenogenetic embryonic stem （pES） cells, generated from oocytes by artificial activation without involvement of fertilization, show differentiation and pluripotency as evi- denced by their capacity to generate germline chimeras and all pES pups by tetraploid embryo complementation, indi- cating the ability of pES cells to form all cell types in the body （Chen et al., 2009; liu et al., 2011）. Indeed, pES cells can repair injured muscle （Koh et al., 2009） and cardiomyocytes with reduced risk of tumorigenesis （liu et al., 2013）,

关键词： Telomere elongation parthenogenetic stem cells artificial activation

The effects of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents:a meta-analysis

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Neural Regeneration Research 2025年第5期20卷 1513-1520页

作者： Xueyun Shao Longfei He Yangyang liu Physical Education School Shenzhen UniversityShenzhenGuangdong ProvinceChina Shenzhen Institute of Neuroscience ShenzhenGuangdong ProvinceChina

Brain-derived neurotrophic factor is a crucial neurotrophic factor that plays a significant role in brain health. Although the vast majority of meta-analyses have confirmed that exercise interventions can increase brain-derived neurotrophic factor levels in children and adolescents, the effects of specific types of exercise on brain-derived neurotrophic factor levels are still controversial. To address this issue, we used meta-analytic methods to quantitatively evaluate, analyze, and integrate relevant studies. Our goals were to formulate general conclusions regarding the use of exercise interventions, explore the physiological mechanisms by which exercise improves brain health and cognitive ability in children and adolescents, and provide a reliable foundation for follow-up research. We used the Pub Med, Web of Science, Science Direct, Springer, Wiley Online Library, Weipu, Wanfang, and China national Knowledge Infrastructure databases to search for randomized controlled trials examining the influences of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents. The extracted data were analyzed using Review Manager 5.3. According to the inclusion criteria, we assessed randomized controlled trials in which the samples were mainly children and adolescents, and the outcome indicators were measured before and after the intervention. We excluded animal experiments, studies that lacked a control group, and those that did not report quantitative results. The mean difference(MD;before versus after intervention) was used to evaluate the effect of exercise on brain-derived neurotrophic factor levels in children and adolescents. Overall, 531 participants(60 children and 471 adolescents, 10.9–16.1 years) were included from 13 randomized controlled trials. Heterogeneity was evaluated using the Q statistic and I^(2) test provided by Review Manager software. The meta-analysis showed that there was no heterogeneity among the studies(P = 0.67,

关键词： adolescents brain-derived neurotrophic factor children exercise meta-analysis randomized controlled trials

The role of axon guidance molecules in the pathogenesis of epilepsy

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Neural Regeneration Research 2025年第5期20卷 1244-1257页

作者： Zheng liu Chunhua Pan Hao Huang Department of Neurology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence suggests that axon guidance molecules play a role in the structural and functional modifications of neural networks and that the dysregulation of these molecules is associated with epilepsy susceptibility. In this review, we discuss the essential role of axon guidance molecules in neuronal activity in patients with epilepsy as well as the impact of these molecules on synaptic plasticity and brain tissue remodeling. Furthermore, we examine the relationship between axon guidance molecules and neuroinflammation, as well as the structural changes in specific brain regions that contribute to the development of epilepsy. Ample evidence indicates that axon guidance molecules, including semaphorins and ephrins, play a fundamental role in guiding axon growth and the establishment of synaptic connections. Deviations in their expression or function can disrupt neuronal connections, ultimately leading to epileptic seizures. The remodeling of neural networks is a significant characteristic of epilepsy, with axon guidance molecules playing a role in the dynamic reorganization of neural circuits. This, in turn, affects synapse formation and elimination. Dysregulation of these molecules can upset the delicate balance between excitation and inhibition within a neural network, thereby increasing the risk of overexcitation and the development of epilepsy. Inflammatory signals can regulate the expression and function of axon guidance molecules, thus influencing axonal growth, axon orientation, and synaptic plasticity. The dysregulation of neuroinflammation can intensify neuronal dysfunction and contribute to the occurrence of epilepsy. This review delves into the mechanisms associated with

关键词： axon guidance drug-resistant epilepsy epilepsy nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity neurons synaptic remodeling

不同热处理蛋黄脂质对小鼠学习认知能力下降的缓解能力

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食品工业科技 2025年第1期46卷 367-376页

作者：吴瑶刘铭坤方冰张明合肥工业大学食品与生物工程学院安徽合肥230061 中国农业大学营养与健康系北京100083 北京工商大学食品与健康学院北京100048

为探讨不同温度处理下蛋黄脂质对小鼠学习认知能力下降的缓解能力的差异。本研究利用小鼠认知障碍模型,比较95℃(水浴30 min)和121℃(灭菌锅加热30 min)热处理蛋黄脂质组分改善小鼠学习认知能力的差异。研究结果表明,相较于121℃热处理... 详细信息

为探讨不同温度处理下蛋黄脂质对小鼠学习认知能力下降的缓解能力的差异。本研究利用小鼠认知障碍模型,比较95℃(水浴30 min)和121℃(灭菌锅加热30 min)热处理蛋黄脂质组分改善小鼠学习认知能力的差异。研究结果表明,相较于121℃热处理的蛋黄脂质,95℃热处理的蛋黄脂质更有效地降低了Tau蛋白的磷酸化和Aβ1-40、GSK-3β表达,下调了促炎因子的表达,其提升小鼠的学习记忆能力的效果更好。95℃热处理蛋黄脂质中的多不饱和脂肪酸以及DHA较121℃热处理的蛋黄脂质显著增加(P<0.05)。因此,过度的加热条件,会破坏蛋品中DHA等多不饱和脂肪酸,削弱蛋黄脂质的改善认知的生物活性。本研究为蛋制品的热加工工艺的优化提供参考依据。

关键词：蛋黄脂质热处理学习和记忆

Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3287-3301页

作者： Ziwei Fan Mengxian Jia Jian Zhou Zhoule Zhu Yumin Wu Xiaowu Lin Yiming Qian Jiashu Lian Xin Hua Jianhong Dong Zheyu fang Yuqing liu Sibing Chen Xiumin Xue Juanqing Yue Minyu Zhu Ying Wang Zhihui Huang Honglin Teng Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Neurology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina

The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord *** of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be *** possesses an anti-inflammatory biological ***,its roles and the underlying molecular mechanisms in spinal cord injury remain *** this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in *** promoted M2 polarization through inactivating the cGAS/STING/NF-κB ***,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord ***,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal *** together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.

关键词： cGAS/STING functional recovery microglia neuroinflammation neuroprotection nuclear factor-κB polarization spinal cord injury tryptanthrin