Telomere elongation in parthenogenetic stem cells

作     者：Yu Yin Na Liu Xiaoying Ye Renpeng Guo Jie Hao Fang Wang Lin Liu 

作者机构：State Key Laboratory of Medicinal Chemical BiologyDepartment of Cell Biology and GeneticsCollege of Life SciencesNankai UniversityTianjin 300071China 

出 版 物：《Protein & Cell》 (蛋白质与细胞（英文版）)

年 卷 期：2014年第5卷第1期

页      面：8-11页

核心收录：

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1007[医学-药学(可授医学、理学学位)] 1002[医学-临床医学] 07[理学] 08[工学] 071009[理学-细胞生物学] 09[农学] 0703[理学-化学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：supported by the National Basic Research Program (973 Program) 国家自然科学基金 

主　　题：Telomere Length Somatic Cell Nuclear Transfer Relative Telomere Length Telomere Elongation Longe Telomere 

摘      要：Dear Editor, Parthenogenetic embryonic stem （pES） cells, generated from oocytes by artificial activation without involvement of fertilization, show differentiation and pluripotency as evi- denced by their capacity to generate germline chimeras and all pES pups by tetraploid embryo complementation, indi- cating the ability of pES cells to form all cell types in the body （Chen et al., 2009; Liu et al., 2011）. Indeed, pES cells can repair injured muscle （Koh et al., 2009） and cardiomyocytes with reduced risk of tumorigenesis （Liu et al., 2013）,