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Integrated positron emission tomography and computed tomography in preoperative lymph node staging of non-small cell lung cancer

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Chinese Medical Journal 2014年第4期127卷 607-613页

作者： Xu N Jiao Y fang wg Wang MZ Zhu ZH Zhang YQ Department of General Internal Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences &amp Peking Union Medical College Beijing 100730 China Department of Respiratory Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences &amp Peking Union Medical College Beijing 100730 China Department of Nuclear Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences &amp Peking Union Medical College Beijing 100730 China

Background Integrated positron emission tomography and computed tomography （PET/CT） is increasingly used for the preoperative nodal staging of non-smail cell lung cancer （NSCLC）.The aim of this study was to evaluate the accuracy of PET/CT in comparison with CT in detection of nodal metastasis and preoperative nodal staging in patients with NSCLC,and to analyze the causes of the PET/CT false-negative and false-positive *** Consecutive patients with pathologically proven NSCLC who underwent staging using PET/CT from July 2008 to February 2012 were evaluated *** staging was pathologically confirmed on tissue specimens obtained at *** accuracy of PET/CT and CT in the assessment of intrathoracic nodal involvement was determined using histological results as the reference *** regression was used to define the causes of the false-negative and false-positive *** A total of 528 lymph node stations were evaluated in 101 *** nodes were positive for malignancy in 43 out of 101 patients （42.6%）,and 101 out of 528 nodal stations （19.2%）.PET/CT was significantly more accurate for nodal staging than *** sensitivity,specificity,positive and negative predictive values,and accuracy of PET/CT for detecting nodal metastasis were 51.5%,95.8%,74.3%,89.3%,and 87.3% and the corresponding data by CT were 45.5%,87.1%,45.5%,87.1%,and 79.2%,***/CT confers significantly higher specificity,positive predictive value,and accuracy than CT in detecting nodal ***-negative results by PET/CT are significantly associated with smaller lymph node size,whereas false-positive results are related to a combination of inflammatory disorders and larger lymph node *** PET/CT confers significantly higher accuracy than CT in nodal staging,and is more specific and accurate than CT in detecting nodal metastasis but has a low sensitivity and high false-negative rate.

关键词： positron emission tomography computed tomography non-small cell lung cancer preoperative lymph node staging

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Energy Harvesting in the Wake of An Inverted C-Shaped Bluff Body

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China Ocean Engineering 2024年第1期38卷 68-80页

作者： WANG Jun-lei LI Shen-fang Md.Mahbub ALAM ZHU Hong-jun HU Guo-biao School of Mechanical and Power Engineering Zhengzhou UniversityZhengzhou 450000China Center for Turbulence Control Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China Internet of Things Thrust The Hong Kong University of Science and Technology(Guangzhou)Guangzhou 511400China

This paper proposes a novel wake-induced vibration(WIV)-based energy harvesting system consisting of two bluff *** inverted C-shaped bluff body is stationary installed at the upstream position to generate an interference wake street,and a cylinder bluff body equipped with a transducer is elastically suspended at the downstream position to harness WIV *** hydrodynamics and energy harvesting(EH)performance of the proposed system are investigated via experimental *** reduced velocity(U*)ranging from 2 to 14(the corresponding Reynolds number ranging from 15100 to 106200)is considered in the present *** is found that the wake generated by the inverted C-shaped bluff body significantly affects the EH *** the opening angle(α)of the C-shaped bluff body increases the vibration amplitude of the downstream cylinder,thereby increasing the harvested *** the spacing(L)between two bluff bodies is two times the cylinder diameter(D),the wake-induced vibration(WIV)mode is observed,while the combined WIV and wake galloping(wg)mode occurs whenαis 150°,and L equals 3D or *** average drag coefficient becomes negative when L is 2D,3D,or *** carefully configuring a C-shaped bluff body,the wake generated by it can bring an augmenting effect on the vibration of the downstream EH *** example,the RMS power output of the proposed EH system reaches a maximum of 0.31 W at U*=8 and L=4D,which is 300%greater than that of its traditional ***,after a number of case stud-ies,it is identified that the proposed EH system can achieve the best performance whenαis 150°and L=2D.

关键词： wake-induced vibration vortex-induced vibration galloping energy harvesting bluff body

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武汉市成人甲状腺容积调查及相关影响因素分析

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中华地方病学杂志 2024年第7期43卷 564-569页

作者：陈芳杨燕徐文秀罗华堂武汉市疾病预防控制中心血吸虫病与地方病防制所武汉

目的了解武汉市成人甲状腺容积及甲状腺肿状况, 分析其相关影响因素, 为修订成人甲状腺肿诊断标准提供依据。方法 2019年12月至2021年11月, 在武汉市13个区, 采用多阶段整群随机抽样方法, 每个区抽取2个社区或乡镇, 每个社区或乡镇按纳... 详细信息

目的了解武汉市成人甲状腺容积及甲状腺肿状况, 分析其相关影响因素, 为修订成人甲状腺肿诊断标准提供依据。方法 2019年12月至2021年11月, 在武汉市13个区, 采用多阶段整群随机抽样方法, 每个区抽取2个社区或乡镇, 每个社区或乡镇按纳入排除标准选取16岁以上常住居民100人, 进行一般资料收集、甲状腺超声检查、尿碘检测、体格检查, 并分析甲状腺容积的影响因素。结果共抽取武汉市16岁以上成人2 578人, 男性1 168人、女性1 410人, 年龄为(41.79 ± 13.01)岁。成人甲状腺容积中位数(四分位数间距)为6.36(4.88, 8.11)ml, 甲状腺肿大率为0.70%(18/2 578), 甲状腺结节检出率为35.49%(915/2 578);尿碘中位数(四分位数间距)为185.32(107.93, 277.08)μg/L。经Spearman相关分析, 武汉市成人甲状腺容积与其身高、体重、身体质量指数(BMI)、体表面积(BSA)均呈正相关(r = 0.12、0.22、0.21、0.20, 均P < 0.001)。经多元线性回归分析, 得到回归方程:甲状腺容积= 7.72 + 1.19 ×是否患甲状腺结节- 1.04 ×性别+ 0.15 ×年龄分组, 患甲状腺结节者甲状腺容积大于未患者、男性大于女性、高龄组大于低龄组。结论武汉市成人甲状腺肿大率较低, 性别、年龄、是否患甲状腺结节以及身高、体重、BMI、BSA等身体测量因素是甲状腺容积的影响因素。

关键词：成人甲状腺容积甲状腺肿影响因素

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冷轧压下率对300wg钢组织织构的影响

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河南冶金 2024年第3期32卷 11-14页

作者：谢芳陈建华袁武新余钢铁股份有限公司江西新余338000

通过对退火板300wg钢进行不同冷轧压下率的相关试验,分析研究冷轧压下率对300wg钢组织性能及内部织构的影响规律。试验结果表明:随着冷轧压下率的不断提高,冷轧后的铁素体晶粒组织在轧制力作用下沿轧制方向不断被拉长,沿板厚方向呈不断... 详细信息

通过对退火板300wg钢进行不同冷轧压下率的相关试验,分析研究冷轧压下率对300wg钢组织性能及内部织构的影响规律。试验结果表明:随着冷轧压下率的不断提高,冷轧后的铁素体晶粒组织在轧制力作用下沿轧制方向不断被拉长,沿板厚方向呈不断压缩,晶粒尺寸不断变大,晶粒位错密度也不断增加;冷轧压下率从0提升至25%时,钢板维氏硬度急剧升高,冷轧压下率从25%至75%时,钢板维氏硬度变化不明显;冷轧后的300wg钢在γ纤维织构上的{111}和{111}织构得到了加强。

关键词： 300wg钢压下率晶粒组织织构

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Simultaneous recovery of carbon and sulfur resources from reduction of CO_2 with H_2S using catalysts

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Journal of Energy Chemistry 2016年第1期25卷 110-116页

作者： Hui Su Yuyang Li Ping Li Yongxiu Chen Zhizhi Zhang Xiangchen fang State Key Laboratory of Chemical Engineering East China University of Science and Technology Fushun Research Institute of Petroleum & Petrochemicals Sinopec

An approach to the simultaneous reclamation of carbon and sulfur resources from CO2 and H2S has been proposed and effectively implemented with the aid of catalysts. A brief thermodynamic study reveals the potential of direct reduction of CO2 with H2S（15：15 mol% balanced with N2） for selective production of CO and elemental sulfur. The experiments carried out in a fixed-bed flow reactor over the temperature range of 400–800 °C give evidence of the importance of the employment of catalysts. Both the conversions of the reactants and the selectivities of the target products can be substantially promoted over most catalysts studied. Nevertheless, little difference appears among their catalytic performance. The results also prove that the presence of CO2 can remarkably enhance H2S conversion and the sulfur yield in comparison with H2S direct decomposition. A longtime reaction test on Mg O catalyst manifests its superior durability at high temperature（700 °C） and huge gas hourly space velocity（100,000 h-1）. Free radicals initiated by catalysts are supposed to dominate the reactions between CO2 and H2S.

关键词： Carbon dioxide Hydrogen sulfide Simultaneous recovery Reduction Catalyst

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原花青素对泥鳅生长、免疫功能及抗氧化能力的影响

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饲料工业 2024年第4期45卷 55-61页

作者：方琼亚孔祎頔李民李科刘晓蕊刘海惠王桂芹吉林农业大学动物科学技术学院动物生产及产品质量安全教育部重点实验室现代农业技术教育部国际合作联合实验室吉林省动物营养与饲料科学重点实验室吉林长春130118

研究旨在探究原花青素(Oligomeric proanthocyanidins,OPC)对泥鳅生长、免疫功能及抗氧化能力的影响。在基础饲料中分别添加0、100、200、400 mg/kg和800 mg/kg OPC[分别记为对照(CON)、OPC100、OPC200、OPC400、OPC800组],饲喂300尾初始体重为(2.13±0.01)g的泥鳅。进行8周的饲养试验后,测定泥鳅的生长性能、血清免疫指标及肝脏、肠道中抗氧化酶活性。结果表明:随着OPC添加量的增加,泥鳅的特定生长率(SGR)、终末体质量(FBW)、增重率(wg)和蛋白质效率(PER)显著升高(P<0.05),饲料系数(FCR)显著下降;OPC400组泥鳅肥满度显著下降(P<0.05),OPC200、400组的泥鳅肝体比显著降低(P<0.05);OPC400、800组的泥鳅血清中的谷草转氨酶(AST)显著降低(P<0.05);OPC200、400、800组泥鳅血清中的谷丙转氨酶(ALT)显著降低(P<0.05),显著提高血清中补体4(C4)和溶菌酶(LYS)水平(P<0.05),且各组补体3(C3)含量均显著升高(P<0.05);OPC400、800组的肝脏中过氧化氢酶(CAT)和谷胱甘肽-S-转移酶(GST)活性显著升高(P<0.05);OPC200、400、800组的肠道中CAT、谷胱甘肽过氧化物酶(GSH-Px)、GST、超氧化物歧化酶(SOD)及肝脏中SOD和谷胱甘肽(GSH)活性显著高于对照组(P<0.05),且各组肠道中GSH活性均显著提升(P<0.05),而所有组肝脏和肠道的丙二醛(MDA)含量显著下降(P<0.05);综上,饲料中添加200~400 mg/kg OPC能够增强泥鳅生长、改善免疫能力和提高抗氧化能力。

关键词：原花青素泥鳅生长免疫功能抗氧化能力

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Spontaneous emission rate enhancement of nano-structured silicon by surface plasmon polariton

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Frontiers of Optoelectronics 2012年第1期5卷 51-62页

作者： Xue FENG fang LIU Yidong HUANG State Key Laboratory of Integrated Optoelectronics Department of Electronic EngineeringTsinghua UniversityBeijing 100084China

Surface plasmon polariton （SPP） is an attractive candidate to improve internal quantum efficiency （QE） of spontaneous emission （SE） from nano-structured silicon （Si） including nano-porous silicon （NP-Si） and silicon nanocrystal （Si-NC）. Since the SPP resonant frequency of common metals, e.g., gold （Au）, silver （Ag）, copper （Cu）, and aluminum （A1）, is too high, the SPP resonance has to be engineered to match the luminescence from nano- structured Si. For this purpose, we have proposed and demonstrated three approaches including metal-rich Au（1-a）-SiO2（a） cermet SPP waveguide （wg）, com- pound layer structure wg and metallic grating. In this paper, those approaches are reviewed and discussed. According to the calculated results, such three methods could effectively enhance SE rate from NP-Si or Si-NCs and show potential in developing high efficiency Si based light sources with electric pump.

关键词： spontaneous emission (SE) silicon nanocrys-tal (Si-NC) surface plasmon polariton (SPP) Purcell effect

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DRG改革背景下运用灰色关联度法提高临床路径管理效果分析

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中国社会医学杂志 2024年第1期41卷 37-40页

作者：房莉胡旻慧李佺杨青罗艺武汉市肺科医院湖北武汉430030

目的探讨医院临床路径实施中的重点管理工作,以提高临床路径实施效果,为医院疾病诊断相关分组(diagnosis related groups,DRG)支付改革提供保障。方法通过灰色关联度分析法对武汉市某肺科专科医院2019年1-12月纳入临床路径管理的病例... 详细信息

目的探讨医院临床路径实施中的重点管理工作,以提高临床路径实施效果,为医院疾病诊断相关分组(diagnosis related groups,DRG)支付改革提供保障。方法通过灰色关联度分析法对武汉市某肺科专科医院2019年1-12月纳入临床路径管理的病例进行分析,筛选出重点指标加强管理,比较管理前后覆盖率、入径率、平均住院天数和平均住院费用等临床路径相关指标。使用秩和检验比较2019年、2020年和2021年完成临床路径管理的患者病种(组)权重/分值(relative weight,RW)区间分组之间差异情况。结果临床路径实施效率影响因素从大到小排序为覆盖率(0.953 4)>入径率(0.948 2)>平均住院天数(0.942 5)>变异完成率(0.805 8)>正常完成率(0.782 8)>变异退出率(0.718 9),经过强化重点工作管理以后,临床路径相关指标覆盖率、入径率和入径完成率均有所提高,平均住院天数有所降低,2019年、2020年和2021年完成临床路径管理的患者RW区间分组≥2的比例逐年提高,平均住院费用处于平稳不增状态。结论灰色关联度分析有助于明确临床路径开展中的重点工作,对重点指标加强管理,起到了良好的监管效果,进一步促进DRG改革有效落实。

关键词：灰色关联度法临床路径疾病诊断相关分组

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Relationship between left-behind status and cognitive function in older Chinese adults: a prospective 3-year cohort study

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General Psychiatry 2023年第3期36卷 148-157页

作者： Hong-Guang Zhang fang Fan Bao-Liang Zhong Helen Fung-Kum Chiu Department of Psychiatry Affiliated Wuhan Mental Health CenterTongji Medical College of Huazhong Universityof Science&TechnologyWuhanHubeiChina Department of Psychiatry Wuhan Mental Health CenterWuhanHubeiChina Department of Clinical Psychology Wuhan Hospital for PsychotherapyWuhanHubeiChina Department of Psychiatry The Chinese University of Hong KongHong KongChina

Background Due to the inaccuracy of the traditional geographical distance-based definition of left-behind status,data on the negative effect of left-behind status on cognitive function among older adults are *** This study examined the cross-sectional and longitudinal associations of left-behind status with cognitive function in older Chinese *** left-behind status definition was based on the frequency of face-to-face parent-child *** Data from a nationally representative sample of 8682 older adults(60+years)in 2015(5658 left behind and 3024 non-left behind),of which 6933 completed the follow-up in 2018,were obtained from the China Health and Retirement Longitudinal ***-behind older adults werebroadlydefined as those aged 60+years who had living adult children and saw their children less than once per *** cognitive function was assessed with a composite cognitive test with higher total scores indicating better cognitive *** Left-behind older adults had significantly lower cognitive test scores than non-left-behind older adults in both 2015(11.1(6.0)vs 13.2(5.9),t=15.863,p<0.001)and 2018(10.0(6.6)vs 12.4(6.7),t=14.177,p<0.001).After adjusting for demographic factors,lifestyle factors,chronic medical conditions and the baseline cognitive test score(in the longitudinal analysis only),on average,the cognitive test score of left-behind older adults was 0.628 lower than their non-left-behind counterparts in 2015(t=5.689,p<0.001).This difference in cognitive test scores attenuated to 0.322 but remained significant in 2018(t=2.733,p=0.006).Conclusions Left-behind older Chinese adults have a higher risk of poor cognitive function and cognitive decline than their non-left-behind *** efforts targeting left-behind older adults,such as encouraging adult children to visit their parents more regularly,are warranted to maintain or delay the progression of cognitive decline.

关键词： function cognitive maintain

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The effects of maltodextrin/starch in soy protein isolate–wheat gluten on the thermal stability of high-moisture extrudates

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Journal of Integrative Agriculture 2023年第5期22卷 1590-1602页

作者： XIE Si-han WANG Zhao-jun HE Zhi-yong ZENG Mao-mao QIN fang Benu ADHIKARI CHEN Jie State Key Laboratory of Food Science and Technology Jiangnan UniversityWuxi 214122P.R.China Collaborative Innovation Center of Food Safety and Quality Control Jiangnan UniversityWuxi 214122P.R.China Analysis Centre Jiangnan UniversityWuxi 214122P.R.China School of Science RMIT UniversityMelbourneVIC 3083Australia

This study aimed to investigate the interaction between maltodextrin/starch of different molecular weight distributions and soy protein isolate (SPI)–wheat gluten (wg) matrix during high-moisture *** maltodextrins (dextrose equivalent (DE):10 and 20) and wheat starch were extruded with SPI–wg blend in a system of 65,70,and 75%moisture to investigate their effects on texture and thermal *** 5%maltodextrin (DE10) in the SPI–wg matrix improved the fiber structure and thermal *** wheat starch was thoroughly gelatinized during subsequent sterilization,the fiber structure and thermal stability were also *** was found that the plasticization caused by small-molecular weight saccharides and enhanced phase separation caused by large-molecular weight saccharides changed the melting temperature of blends and significantly improved the texture and thermal stability of extrudates.

关键词： high-moisture extrusion protein saccharide fiber structure textural properties rheology plasticization phase separation

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