检索结果-南通市图书馆

TK50/AP复合物三维纳米网格结构的构筑及其性能研究

在线全文

学校读者我要写书评

暂无评论

化学研究与应用 2024年第4期36卷 704-712页

作者：李岚龙亭宇游婷冯晓军段晓惠西南科技大学环境友好能源材料国家重点实验室四川绵阳621010 西安近代化学研究所陕西西安710065

为了改善1,1’-二羟基-5,5’-联四唑二羟胺盐(TK50)的释能特性,采用冰模板法构筑了TK50/高氯酸铵(AP)(TK50/AP)复合物三维纳米网格结构。通过场发射扫描电子显微镜、X射线粉末衍射、差示扫描量热仪、比表面积和孔径分析仪、热-红联用仪... 详细信息

为了改善1,1’-二羟基-5,5’-联四唑二羟胺盐(TK50)的释能特性,采用冰模板法构筑了TK50/高氯酸铵(AP)(TK50/AP)复合物三维纳米网格结构。通过场发射扫描电子显微镜、X射线粉末衍射、差示扫描量热仪、比表面积和孔径分析仪、热-红联用仪及激光点火装置对其形貌、微结构、热分解和燃烧性能进行了研究。结果表明,TK50/AP复合物的三维纳米网格结构包含大量的中孔(2~6 nm),比表面积和孔体积分别为7.059m^(2)·g^(-1)和0.09 cm^(3)·g^(-1)。XRD衍射峰强度大大降低,由Scherrer公式计算的平均晶粒度为83.80 nm。DSC曲线有2个放热峰,位于228.1℃处尖锐的强放热峰,其峰温较原料TK50提前12℃,活化能增加144.86 kJ·mol^(-1);位于325.6℃处弱的宽峰,其峰温较原料AP提前105.6℃,活化能增加24.21 kJ·mol^(-1)。热-红联用测试结果表明复合物的热分解速率更快、能量释放更完全。TK50/AP复合物表现出高效稳定的激光点火燃烧(LIC)性能,点火延迟时间从原料TK50的50 ms、混合物的60 ms降低到20 ms,激光点火阈值从原料TK50的25.12 mJ、混合物的12.56 mJ降低到6.28 mJ。复合物的纳米尺寸效应和多孔网格结构优异的传热传质特性是其热分解和LIC性能显著改善的主要原因。

关键词： TK50 AP 冰模板三维纳米网格热分解激光点火燃烧

Temperature Distribution of Iron Ore Pellet Bed in Grate

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2012年第2期19卷 7-11页

作者： feng jun-xiao XIE Zhi-yin CHEN Yan-mei School of Mechanical Engineering University of Science and Technology Beijing Beijing 100083 China

The temperature distribution of iron ore pellet bed in grate has a significant effect on pellet production and quality control, but the related work is scarce. A well-designed test was successfully carried out by means of tracking measurement and the temperature distribution and variation in pellet layers were obtained. The effects of blast tem- perature, blast velocity and oxidation reaction on the pellet layer temperature were studied. According to the analy- sis, the inlet air temperature in the up-draught drying zone （UDD） and blast temperature in the Preheating I （PH I） zone should be raised, and the length of the down-draught drying zone （DDD） should be properly increased.

关键词： grate iron ore pellet bed temperature distribution industrial test

Recent advances in vacancy engineering for reliable lithiumsulfur batteries

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第2期43卷 455-477页

作者： Wen-Dong Liu xiao Tang jun-An feng Chao-Yue Zhang Hao Liu Chuan Shi xiao-Xian Zhao Jian-jun Song College of Physics School of Chemistry and Chemical EngineeringQingdao UniversityQingdao266071China Faculty of Science Centre for Clean Energy TechnologySchool of Mathematical and Physical SciencesUniversity of Technology SydneySydneyNSW2007Australia Department of Chemistry College of ScienceHebei Agricultural UniversityBaoding071001China

The high-energy-density and low-cost features endow lithium-sulfur batteries with broad application ***,many drawbacks,especially the detrimental shuttle effect,have hindered the further development of *** response,a lot of new structures have been applied to suppress the shuttle effect and promote the development of ***,vacancy engineering has gained the attention of researchers due to its unique electronic *** review aims to analyze the application of vacancy engineering in ***,the electrochemistry of LSBs has been systematically discussed and the existing challenges as well as improvement tactics of LSBs have also been ***,the preparation methods and characterization technologies of various vacancies are summarized,including oxygen vacancies,sulfur vacancies,selenium vacancies,other anion vacancies,cation vacancies,*** latest applications of vacancy engineering in LSBs are also summarized in this ***,some prospects and insights for further investigation and practical application of vacancy engineering in LSBs are put forward.

关键词： Lithium-sulfur batteries(LSBs) Defects Vacancy engineering Electronic structure Shuttle effect

Diagnosis and treatment of biliary mucinous cystic neoplasms: A single-center experience

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 495-501页

作者： jun-jun Jia Ya-Fen Cheng Mei-Bao feng Li Liu Ming-Qi Shuai xiao-Dong Shen xiao-feng Tang Shu-Sen Zheng Division of Hepatobiliary and Pancreatic Surgery Department of Surgerythe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of International Healthcare Center the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Pathology the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Library the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Background: Biliary mucinous cystic neoplasms(BMCNs) are rare hepatobiliary cystic tumors, which can be divided into noninvasive and invasive types. This study aimed to investigate the diagnosis, treatment, and prognosis of BMCNs in a large single center. Methods: We analyzed 49 patients with BMCNs confirmed by postoperative pathology at the First Afflliated Hospital, Zhejiang University School of Medicine between January 2007 and December 2021. Results: Among the 49 patients, 37 were female(75.5%), and the average age was 57.04 years. Common symptoms included abdominal discomfort, jaundice and fever, while 22 patients(44.9%) had no symptoms. Serum carbohydrate antigen(CA) 19-9 and CA125 concentrations were elevated in 34.8% and 19.6% of patients, respectively. Forty-eight patients had tumors in the intrahepatic bile ducts and only one had a tumor in the extrahepatic bile duct. Forty-eight patients with noninvasive intrahepatic BMCNs were further analyzed in terms of pathological features: 34(70.8%) had low-grade intraepithelial neoplasms(LGINs), and 14(29.2%) had high-grade intraepithelial neoplasms(HGINs). The potential immunohistochemical markers of BMCNs were cytokeratin(CK) 19, CK7, estrogen receptor and progesterone receptor. Follow-up data for 37 patients with intrahepatic BMCNs were obtained. The median overall survival(OS) of BMCNs was not reached. The longest survival time was 137 *** 5-and 10-year OS rates were 100% and 85.4%, respectively. The 5-and 10-year recurrence-free survival(RFS) rates were 93.9% and 80.2%, respectively. Conclusions: BMCNs are rare cystic neoplasms that commonly occur in middle-aged females. BMCNs can only be diagnosed and classified by postoperative pathology, as there are no specific clinical presentations, serological indicators or imaging modalities for preoperative diagnosis. Complete surgical resection is necessary for BMCNs, and the postoperative prognosis is favorable.

关键词： Biliary mucinous cystic neoplasms Low-grade intraepithelial neoplasms High-grade intraepithelial neoplasms Overall survival Recurrence-free survival

Shear-thinning Catechol-modified Chitosan Hydrogel Loaded with Silver Nanoparticles for Endoscopic Submucosal Dissection

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第8期42卷 1147-1155页

作者： Wen-jun feng Yan-He Wu xiao-Yang Liu Zheng-Ke Wang MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China

Shear-thinning hydrogels have emerged for endoscopic submucosal dissection,while wound intervention after surgery has rarely been ***,a catechol-modified chitosa n hydrogel with shear-thinning property was developed for simultaneously facilitating endoscopic submucosal dissection and postoperative wound *** from the shear-thinning and self-healing characteristics,the asprepared hydrogel showed easily endoscopic *** also performed very well as submucosal cushion,which could remain above 70%after injection for 120 min in ex vivo porcine large intestine *** fact,the cushion height of normal saline dramatically decreased to 46%of the initial height at 30 *** nanoparticles encapsulated into the network endowed the hydrogel with almost reached 100%antibacterial effect against *** and *** hemolysis ratio of the hydrogel was calculated to be as low as 0.8%.Combined with good hemocompatibility and cytocompatibility,the as-prepared hydrogel displayed much higher in vivo wound closu re and healing efficacy than normal *** results demonstrated the superiority of the shear-thinning chitosan hydrogel in facilitating clinical endoscopic submucosal dissection surgery.

关键词： Shear-thinning hydrogel Endoscopic mucosal dissection Wound healing Catechol-modified chitosan Silver nanoparticles

Metamorphic P-T conditions and ages of garnet-biotite schists in the Dahongshan Group from the southwestern Yangtze Block

在线全文

学校读者我要写书评

暂无评论

Acta Geochimica 2024年第4期43卷 707-718页

作者： jun-xiao Ma Guang-shu Yang Yong-feng Yan xiao-Fei Xu Yun-hua Ren Hui Zhao xiao-jun Zheng Yuan Qin Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming 650093China Geological Team 306 of Yunnan Non-Ferrous Metals Geological Bureau Kunming 650217China Yunnan Provincial Bureau of Non-Ferrous Geology Kunming 650051China

The Dahongshan Group,situated at the southwestern margin of the Yangtze Block,represents a geological unit characterized by relatively high-grade metamorphism in the *** paper investigates the garnet-biotite schist from the Laochanghe Formation of the Dahongshan Group,employing an integrated approach that includes petrological analysis,phase equilibrium modeling,and zircon U-Pb *** schist is mainly composed of garnet,biotite,plagioclase,quartz,rutile,and *** equilibrium modeling revealed the peak metamorphic conditions of 8-9 kbar and 635-675°*** further integrating the prograde metamorphic profile of garnet and geothermobarometric results,a clockwise P-T metamorphic evolution path is constructed,which includes an increase in temperature and pressure during the prograde ***-ICP-MS zircon U-Pb dating and zircon Ti thermometry constrains the post-peak metamorphic age of 831.2±7.2 *** with previously reported results,it is revealed that the southwestern margin of the Yangtze Block experienced a large-scale regional metamorphism during the Neoproterozoic(890-750 Ma),which is related to the collisional orogenic *** may be associated with the late-stage assembly of the Rodinia supercontinent or with local compression and subduction processes during the breakup of the Rodinia supercontinent.

关键词： Southwestern Yangtze Block Dahongshan Group Phase equilibrium modeling Zircon U-Pb dating Neoproterozoic metamorphism

β-Elemene induces apoptosis and autophagy in colorectal cancer cells through regulating the ROS/AMPK/mTOR pathway

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2022年第1期20卷 9-21页

作者： WANG Guo-Yu ZHANG Lei GENG Ya-Di WANG Bin feng xiao-jun CHEN Zhao-Lin WEI Wei JIANG Ling Department of Pharmacy the First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui230001China Institute of Clinical Pharmacology Anhui Medical UniversityHefei 230001China Department of Pharmacy Hefei Cancer HospitalChinese Academy of SciencesHefei 230031China

β-Elemene is an effective anti-cancer ingredient extracted from the genus Curcuma(Zingiberaceae familiy).In the present study,we demonstrated thatβ-elemene inhibited the proliferation of colorectal cancer cells and induced cell cycle arrest in the G2/M *** addition,β-elemene induced nuclear chromatin condensation and cell membrane phosphatidylserine eversion,decreased cell mitochondrial membrane potential,and promoted the cleavage of caspase-3,caspase-9 and PARP proteins,indicating apoptosis in colorectal cancer *** the same time,β-elemene induced autophagy response,and the treated cells showed autophagic vesicle bilayer membrane structure,which was accompanied by up-regulation of the expression of LC3B and ***,β-elemene increased ROS levels in colorectal cancer cells,promoted phosphorylation of AMPK protein,and inhibited mTOR protein *** the experiments in vivo,β-elemene inhibited the tumor size and induced apoptosis and autophagy in nude *** summary,β-elemene inhibited the occurrence and development of colon cancer xenografts in nude mice,and significantly induced apoptosis and autophagy in colorectal cancer cells in *** effects were associated with regulation of the ROS/AMPK/mTOR *** offered a molecular basis for the development ofβ-elemene as a promising anti-tumor drug candidate for colorectal cancer.

关键词： β-Elemene Colorectal cancer Apoptosis Autophagy AMPK mTOR

Unveiling the Re,Cr,and I diffusion in saturated compacted bentonite using machine-learning methods

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第6期35卷 65-77页

作者： Zheng-Ye feng jun-Lei Tian Tao Wu Guo-jun Wei Zhi-Long Li xiao-Qiong Shi Yong-Jia Wang Qing-feng Li Department of Engineering Huzhou UniversityHuzhou 313000China Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006China College of Physics Science and Technology Shenyang Normal UniversityShenyang 110034China

The safety assessment of high-level radioactive waste repositories requires a high predictive accuracy for radionuclide diffusion and a comprehensive understanding of the diffusion *** this study,a through-diffusion method and six machine-learning methods were employed to investigate the diffusion of ReO_(4)^(−),HCrO_(4)^(−),and I−in saturated compacted bentonite under different salinities and compacted dry *** machine-learning models were trained using two *** dataset contained six input features and 293 instances obtained from the diffusion database system of the Japan Atomic Energy Agency(JAEA-DDB)and 15 *** other dataset,comprising 15,000 pseudo-instances,was produced using a multi-porosity model and contained eight input *** results indicate that the former dataset yielded a higher predictive accuracy than the *** gradient-boosting exhibited a higher prediction accuracy(R2=0.92)and lower error(MSE=0.01)than the other machine-learning *** addition,Shapley Additive Explanations,Feature Importance,and Partial Dependence Plot analysis results indicate that the rock capacity factor and compacted dry density had the two most significant effects on predicting the effective diffusion coefficient,thereby offering valuable insights.

关键词： Machine learning Effective diffusion coefficient Through-diffusion experiment Multi-porosity model Global analysis

Ferritinophagy: A new idea for liver diseases regulated by ferroptosis

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 160-170页

作者： Zi-Bing Qian jun-feng Li Wan-Yuan Xiong xiao-Rong Mao The First Clinical Medical College of Lanzhou University Lanzhou 730000China Institute of Infectious Diseases The First Hospital of Lanzhou UniversityLanzhou 730000China Department of Infectious Disease The First Hospital of Lanzhou UniversityLanzhou 730000China

Background:The discovery of regulatory cell death has led to a breakthrough in the therapeutic *** forms of cell death,such as necrosis,apoptosis,pyroptosis,autophagy,and ferroptosis,play an important role in the development of liver *** general,more than one form of cell death pathways is responsible for the disease ***,it is particularly important to study the regulation and interaction of various cell death forms in liver *** sources:We performed a PubMed search up to November 2022 with the following keywords:ferritinophagy,ferroptosis,and liver *** also used terms such as signal path,inducer,and inhibitor to supplement the query ***:This review summarized the basic characteristics of ferritinophagy and ferroptosis and the regulation of ferroptosis by ferritinophagy and reviewed the key targets and treatment strategies of ferroptosis in different liver ***:Ferritinophagy is a potential therapeutic target in ferroptosis-related liver diseases.

关键词： Ferritinophagy Ferroptosis Liver disease