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Comparison of Effects of Liuzijue Exercise and Conventional Respiratory Training on Patients after Cardiac Surgery:A Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2023年第7期29卷 579-589页

作者： ZHANG Qiao-li GE Min CHEN Cheng fan fu-dong JIN Yan ZHANG Ning WANG Lei Department of Rehabilitation Medicine Nanjing Drum Tower HospitalClinical College of Nanjing University of Chinese MedicineNanjing 210008China Department of Rehabilitation College of Acupuncture and Moxibustion and Massage Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China Department of Cardio-Thoracic Surgery Nanjing Drum Tower Hospitalthe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008China Department of Ultrasound Nanjing Drum Tower Hospitalthe Affi liated Hospital of Nanjing University Medical SchoolNanjing 210008China

Objective To evaluate the feasibility and safety of Liuzijue exercise(LE)for the clinical effect in patients after cardiac *** Totally 120 patients who underwent cardiac surgery and were admitted to the Cardiothoracic Intensive Care Unit of Nanjing Drum Tower Hospital between July and Oclober,2022 were allocated to the LE group,the conventional respiratory training(CRT)group,and the control group by a random number table at a ratio of 1:1:1;40 patients in each *** patients received routine treatment and cardiac *** group and CRT group respectively performed LE and CRT once a day for 30 min for 7 *** group did not receive specialized respiratory *** forced vital capacity,forced expiratory volume in 1 s,peak inspiratory flow rate,peak expiratory flow rate,maximum inspiratory pressure,maximum expiratory pressure,modified Barthel index(MBI),and Hamilton Rating Scale for Anxiety(HAM-A)were evaluated before,after 3 and 7 days of *** addition,the postoperative length of hospital stay(LOS)and the adverse events that occurred during the intervention period were *** A total of 107 patients completed the study,120 patients were included in the *** 3 days of intervention,the pulmonary function,respiratory muscle strength,MBI and HAM-A of all 3 groups improved compared with that before the intervention(Pfunction and respiratory muscle strength were significantly improved in the CRT and LE groups(Pfunction and respiratory muscle strength in the LE group were significantly improved comp

关键词： Liuzijue exercise pulmonary function Liuzijue exercise pulmonary function respiratory muscle strength activities of daily living respiratory muscle strength activities of daily living anxiety cardiac surgery

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Efficacy of intraperitoneal thermochemotherapy and immunotherapy in intraperitoneal recurrence after gastrointestinal cancer resection

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World Journal of Gastroenterology 2002年第6期8卷 1019-1022页

作者： Qing-Guo fu fan-dong Meng Xiao-dong Shen Ren-Xuan Guo,The Second General Surgery Department of The First Clinical College,China Medical University,Shenyang 110001,Liaoning Province,China The Second General Surgery Department of The First Clinical College China Medical University Shenyang 110001 Liaoning Province China. qingguofu@***

AIM:To investigate the prophylactic and therapeutic efficacy of intraperitoneal IL-2 innunotherapy following intraperitoneal thermochemotheray int the metastasis and recurrence of gastric and colorectal cancer after o... 详细信息

关键词：胃肠癌切除术手术后腹膜内复发腹膜内化疗免疫疗法治疗效果

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Preliminary characterization of acute aortic dissection in the mainland of China

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Chinese Medical Journal 2011年第11期124卷 1726-1730页

作者： WANG dong-jin fan fu-dong WANG Qiang LI Qing-guo ZHOU Qing WU Zhong SHI Guang-fei Nanjing Drum Tower Hospital Department of IntegratedTraditional and Western Medicine First Clinical College NanjingUniversity of Traditional Chinese Medicine Nanjing Jiangsu210046 China Department of Cardiothoracic Surgery Department of Cardiology AffiliatedDrum Tower Hospital of Nanjing University Medical SchoolNanjing Jiangsu 210008 China

Objective To explore the differences in the characteristics of acute aortic dissection （AAD） among less and more economically developed countries with various cultures and races. Data sources Reports from the International Registry of Acute Aortic Dissection （IRAD） and the mainland of China （MC） were collected by searching the PubMed Database and the Chinese Journal full-text Database from January 2000 to March 2009. Study selection Those reports from IRAD and MC containing larger numbers of cases and complete patients＇ information were selected, which focused on concrete issues of diagnosing or managing AAD were excluded if they were not able to reflect the overall characteristics of this condition. And the data from the article containing the largest number oatients reDorted bv the same medical center in MC were taken into statistics.

关键词： acute aortic dissection mainland of China the International Registry of Acute Aortic Dissection clinical feature

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恶意透支型信用卡诈骗罪中“催收”问题研究

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河北法学 2012年第3期30卷 186-190页

作者：樊辅东浙江省衢州市柯城区人民检察院浙江衢州324000

根据目前的法律及司法解释,"经二次催收不还"是构成恶意透支的一个必要条件,发卡银行必须实施"催收"行为。由于法律及司法解释并未对催收的含义、催收方式、催收效力认定作出明确规定,导致实践中产生很多争议问题,给认定恶意透支带来困... 详细信息

根据目前的法律及司法解释,"经二次催收不还"是构成恶意透支的一个必要条件,发卡银行必须实施"催收"行为。由于法律及司法解释并未对催收的含义、催收方式、催收效力认定作出明确规定,导致实践中产生很多争议问题,给认定恶意透支带来困难。结合工作实践,通过对立法本意的阐释,对"催收"的本质特征进行分析,提出"催收"是发卡银行向持卡人主张信用卡债权的一种民事行为,"催收"属于犯罪构成的实体要件,"催收"的效力不以对方是否收到催收信息为必要条件。之后对各种催收方式进行归纳分析,并对如何认定催收效力进行论证,最后对立法提出相应建议。

关键词：信用卡诈骗恶意透支催收催收方式催收效力

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Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li dongqing Sun Shaliu fu Lei Gu Xin Shao Qinqin Wang Xin dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao fangqing Zhao Jing-dong J.Han Qi Liu Xiaohui fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

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Development and Application of Equation of State for Square-Well Chain-Like Fluid with Variable Interaction Range

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华东理工大学学报（自然科学版） 2009年第6期35卷 946-946页

作者： LIU Hong-lai LI Jin-long HE Chang-chun fan dong- fu PENG Chang-jun State Key Laboratory of Chemical Engineering Department of Chemistry East China University of Science and Technology Shanghai 200237 China

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老年人急性肺血栓栓塞症的临床表现和危险因素探讨

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中华老年医学杂志 2013年第1期32卷 37-40页

作者：范晓红王春范阜东杨媛华南京大学医学院附属鼓楼医院老年科 210008 南京大学医学院附属鼓楼医院心胸外科 210008 北京朝阳医院呼吸科

目的探讨老年人急性肺栓塞患者临床表现和危险因素的差异。方法将141例经CT肺动脉造影（CTPA）或直接肺动脉造影或放射性核素肺灌注显像结合临床资料确诊的急性肺栓塞患者按年龄分为老年组78例和非老年组63例，比较两组临床表现和危险... 详细信息

目的探讨老年人急性肺栓塞患者临床表现和危险因素的差异。方法将141例经CT肺动脉造影（CTPA）或直接肺动脉造影或放射性核素肺灌注显像结合临床资料确诊的急性肺栓塞患者按年龄分为老年组78例和非老年组63例，比较两组临床表现和危险因素的差异，并选取同时段在我院进行常规体检的100例为对照组，采用多元Logistic回归模型分析老年人急性肺栓塞危险因素。结果老年组和非老年组呼吸困难、咳嗽、胸闷、胸痛的患病率分别为88．5％（69例）与84．1％（53例）、76．9%（60例）与69．8％（44例）、56．4％（44例）与63．5％（40例）、15．4％（12例）与25．4％（16例），两组比较差异无统计学意义（均为P〉0．05），但老年组咯血的患病率9．0％（7例），低于非老年组23．8％（15例）（P〈0．05），老年组无症状患者9．0％（7例）比非老年组1．6％（1例）多，但差异无统计学意义（P〉0．05）；老年组的危险因素多见于糖尿病（X^2=7．41，P〈0．01）、高血压（X^2=14．51，P〈0．01）、慢性阻塞性肺疾病（COPD）（X^2=7．42，P〈0．01）和既往脑卒中（X^2=4．91，P〈0．05），老年组的独立危险因素分别为COPD（OR：3．29，95％CI：1．04～10．46）、既往深静脉血栓史（OR：4．72，95％CI：1．68～13．27）、恶性肿瘤（OR：4．35，95％CI：1．00～18．13，）和既往脑卒中（OR：5．13，95％CI：1．15～24．52）；非老年组为既往深静脉血栓史（OR：11．94，95％CI：3．35～42．60）和恶性肿瘤（OR：11．44，95％CI：1．44～89．92）。结论老年急性肺栓塞患者的临床表现与非老年组相似，多不典型，虽然呼吸困难仍为最常见的临床表现，但不明原因的咳嗽和胸闷应警惕；COPD、恶性肿瘤、既往深静脉血栓和脑卒中史均为老年人急性肺栓塞的独立危险因素，需注意加以鉴别。

关键词：肺栓塞危险因素因素分析,统计学

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Surfing the nano-wave:Emerging trends in cancer diagnostics and therapy

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Nano Research 2025年第1期18卷 520-544页

作者： Genping fu Yuting Weng Yunfan Li Carl Ho Yiyu fu Wenxuan Wang Songbin fu Wenjing Sun Jie Lin Xiaoyu fan Binbin Jia Mengdi Cai Linlin Li Laboratory of Medical Genetics Harbin Medical UniversityHarbin 150081China Key Laboratory of Preservation of Human Genetics Resources and Disease Control in China(Harbin Medical University) Ministry of EducationHarbin 150081China Beijing Key Laboratory for Optical Materials and Photonic Devices Department of ChemistryCapital Normal UniversityBeijing 100048China College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Washington University School of Medicine in St.Louis St.LouisMO 63110USA Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Aix-Marseille College Wuhan University of TechnologyWuhan 430070China

Facing the growing global challenge posed by cancer,the quest for more accurate and potent cancer diagnostic and therapeutic strategies continues to require a multidisciplinary integration *** review firstly summarizes various types of nanoparticles in cancer ***,it offers a comprehensive overview of signalenhancing techniques for visualizing in situ tumors,along with multimodal diagnostic methods for detecting *** for tumor therapy,cutting-edge drug delivery methods that can cross biological barriers and the pinpoint targeting of tumor lesions for precise medical intervention are *** the domain of therapeutic diagnostics,we elucidate the theoretical underpinnings and structural paradigms that underlie a spectrum of advanced diagnostic and therapeutic ***,we present a compendium of publications delineating the clinical applications of each nano-based theragnostic integration ***,this comprehensive review discusses the safety concerns pertaining to the clinical application of nanoparticles and proposes some strategic recommendations to enhance the precision and safety of theragnostic-guided,nanotechnology-based clinical practices.A deeper understanding of nanomaterials,together with intimate interdisciplinary collaborations,nano-wave will most probably guide human beings to win the battle against cancers.

关键词： nanoparticles drug delivery gastric cancer glioma glioblastoma

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Dynamic evolution of Co species and morphological reconstruction on Co-N-C during the nitrate reduction reaction in neutral solution

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Nano Research 2025年第1期18卷 164-172页

作者： Yuanlin fu Xiaoting Yang Ya Yu Kang Zhou Xiaoyang Ye Aoxiang Zhang Xiaojiao Hou Bingbing Chen fuqiang fan Yuhang Li Yu fu Department of Chemistry College of SciencesNortheastern UniversityShenyang 110819China Department of Physical Education Shen Yang Institute of Science and TechnologyShenyang 110167China Sungrow Power Supply Co. Ltd.Hefei 230088China

The electrochemical nitrate reduction reaction(eNO_(3)^(-)RR)is considered an effective approach for converting nitrate-containing wastewater to *** adsorption and activation of NO_(3)^(-)is the critical step for many materials and the high energy barrier inhibits the continuation of the reduction *** Co nanoparticles encapsulated in the carbon layer we prepared spontaneously react with NO_(3)^(-)and the resulting Co^(2+)is then reduced by electroreduction to Co^(0),which circulates *** resulted in overcoming the energy input required for NO_(3)^(-)adsorption and conversion,thereby increasing the catalytic *** the same time,the morphology of the catalyst reconstructed from a dodecahedron to an interwoven nanosheet structure and the increased surface area also gives it better *** obtained Co(OH)_(2)@Co-N-C has an excellent eNO_(3)^(-)RR of 2774.7μg·h^(-1)·cm^(-2)with a Faraday efficiency of 81.4%in neutral *** the same time,the material-modified electrode can run stably for more than 100 *** work provides a new idea for the design of Co-based catalysts for eNO_(3)^(-)RR.

关键词： electrochemical nitrate reduction reaction Co-based catalyst dynamic evolution of Co species morphological reconstruction

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骨髓干细胞移植治疗缺血性心脏病的现状与前景

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心血管病学进展 2008年第5期29卷 778-781页

作者：范阜东王东进南京大学医学院附属鼓楼医院江苏南京210008

心肌梗死后的瘢痕形成及心室重塑严重影响缺血性心脏病人的预后,而常规治疗手段又往往难以奏效,因此关于干细胞移植等的临床研究越来越多,现就骨髓干细胞的分类、移植方法和遇到的问题、前景等作简要介绍。

关键词：缺血性心脏病骨髓干细胞移植

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